Search results for " Feasibility Studie"

showing 5 items of 15 documents

Intensity modulated radiation therapy with simultaneous integrated boost in early breast cancer irradiation. Report of feasibility and preliminary to…

2015

To investigate the feasibility and tolerance in the use of adjuvant intensity modulated radiation therapy (IMRT) and simultaneous integrated boost in patients with a diagnosis of breast cancer after breast-conserving surgery.Between September 2011 to February 2013, 112 women with a diagnosis of early breast cancer (T1-2, N0-1, M0) were treated with IMRT and simultaneous integrated boost after breast-conserving surgery in our institution. A dose of 50Gy in 25 fractions was prescribed to the whole breast and an additional dose of radiation was prescribed on the tumour bed. A dose prescription of 60Gy in 25 fractions to the tumour bed was used in patients with negative margins after surgery, w…

Oncologymedicine.medical_treatmentSegmentalMastectomy SegmentalSeverity of Illness IndexBreast cancerNuclear Medicine and ImagingDuctalIntensity-Modulated80 and overBreastMastectomyAdjuvantEarly breast cancerAged 80 and overCarcinoma Ductal BreastSIBRadiotherapy DosageMiddle AgedOncologyBreast cancer; IMRT; SIB; Toxicity; Adult; Aged; Aged 80 and over; Breast Neoplasms; Carcinoma Ductal Breast; Carcinoma Lobular; Esthetics; Feasibility Studies; Female; Follow-Up Studies; Humans; Mastectomy Segmental; Middle Aged; Radiodermatitis; Radiotherapy Dosage; Radiotherapy Adjuvant; Severity of Illness Index; Radiotherapy Intensity-Modulated; Oncology; Radiology Nuclear Medicine and ImagingToxicityFemaleRadiologyRadiodermatitisRadiologyAdjuvantSimultaneous integrated boostAdultmedicine.medical_specialtyEstheticsBreast NeoplasmsLobularBreast cancerInternal medicineSeverity of illnessmedicineHumansRadiology Nuclear Medicine and imagingIMRTAgedToxicityRadiotherapybusiness.industryCarcinomaIntensity-modulated radiation therapymedicine.diseaseAcute toxicityBreast cancer; IMRT; SIB; Toxicity; Oncology; Radiology Nuclear Medicine and ImagingCarcinoma LobularFeasibility StudiesRadiotherapy AdjuvantRadiotherapy Intensity-ModulatedbusinessFollow-Up Studies
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Electrochemotherapy for advanced cutaneous angiosarcoma: A European register-based cohort study from the International Network for Sharing Practices …

2019

Abstract Background Cutaneous angiosarcoma (cAS) is a highly aggressive malignancy that challenges the radicality of surgical treatment. Electrochemotherapy (ECT), a skin-directed treatment based on cytotoxic chemotherapy combined with local electric pulses, may be an intraoperative adjunct and a new opportunity in the therapeutic strategy. This cohort study reports the experience with ECT as an option. Methods Data on patients with locally-advanced/metastatic cAS who underwent ECT between October 2013 and October 2018 at eight European centres were prospectively submitted to the InspECT (International network for sharing practices of ECT) register. Patients received therapy according to th…

Register basedmedicine.medical_specialtyElectrochemotherapySkin NeoplasmsElectrochemotherapyHemangiosarcomaSkin metastasesTumour controlPainKaplan-Meier EstimateMalignancyCutaneous angiosarcomaCohort Studies03 medical and health sciencesBleomycin0302 clinical medicineAntibioticsSkin Ulcermedicine80 and overHumansAngiosarcomaCutaneous angiosarcoma; Electrochemotherapy; Skin metastases; Skin-directed therapies; Tumour control; Aged; Aged 80 and over; Antibiotics Antineoplastic; Bleomycin; Cohort Studies; Electrochemotherapy; Feasibility Studies; Female; Hemangiosarcoma; Humans; Kaplan-Meier Estimate; Middle Aged; Pain; Patient Reported Outcome Measures; Prospective Studies; Registries; Skin Neoplasms; Skin Ulcer; Treatment OutcomePatient Reported Outcome MeasuresProspective StudiesRegistriesSkin-directed therapiesAgedAged 80 and overInternational networkAntibiotics Antineoplasticbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseAntineoplasticmedicine.anatomical_structureTreatment OutcomeTolerability030220 oncology & carcinogenesisScalpFeasibility Studies030211 gastroenterology & hepatologySurgeryFemaleRadiologybusinessCohort studyInternational journal of surgery (London, England)
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Feasibility of the Allergy Questionnaire for Athletes (AQUA © ) in pediatric age

2018

A burden of respiratory and allergic symptoms up to almost 60% has been observed in young and adult athletes, influencing physical performances1 . The Allergy Questionnaire for Athletes (AQUA©) is a validated screening tool for the prediction of the atopic status in adult athletes2 ; it was recently tested in Belgian young elite athletes (12-14 years old)3 , but its actual feasibility and suitability for children and adolescent was not evaluated. Indeed, there is evidence that children are prone to employ "satisficing" response strategies, answering every question positively/negatively, or simply not answering4 . Therefore, the present cross-sectional survey was carried out to assess feasib…

medicine.medical_specialtyAllergyCross-sectional studyself-reports.ImmunologyMEDLINEAtopy03 medical and health sciences0302 clinical medicinemedicineImmunology and Allergy030212 general & internal medicineAsthmayoung athletesSettore M-EDF/02 - Metodi E Didattiche Delle Attivita' SportivebiologyAthletesbusiness.industrySettore MED/09 - MEDICINA INTERNAAQUA© questionnaireAdolescent; Athletes; Child; Cross-Sectional Studies; Feasibility Studies; Female; Humans; Hypersensitivity; Male; Sports; Surveys and Questionnaires; Pediatrics Perinatology and Child Health; Immunology and Allergy; ImmunologyPediatric ageself-reportsmedicine.diseasebiology.organism_classification030228 respiratory systemFamily medicinePediatrics Perinatology and Child Healthallergy symptoms AQUA© questionnaire feasibility linguistic adaptation young athletes missing answers self-reports.businessSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' Motorieallergy symptomsfeasibilityPediatric Allergy and Immunology
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Smartphone-based ecological momentary assessment (EMA) in psychiatric patients and student controls: A real-world feasibility study

2020

Abstract Background Smartphone-based ecological momentary assessment (EMA) is a promising methodology for mental health research. The objective of this study is to determine the feasibility of smartphone-based active and passive EMA in psychiatric outpatients and student controls. Methods Two smartphone applications —MEmind and eB2— were developed for behavioral active and passive monitoring. The applications were tested in psychiatric patients with a history of suicidal thoughts and/or behaviors (STB), psychiatric patients without a history of STB, and student controls. Main outcome was feasibility, measured as response to recruitment, retention, and EMA compliance. Secondary outcomes were…

medicine.medical_specialtyEcological Momentary AssessmentMEDLINEMESH: SmartphoneRisk monitoringAge and sex[INFO.INFO-MC]Computer Science [cs]/Mobile Computing03 medical and health sciences0302 clinical medicineHumansMedicineIn patientSuicidal patientsStudentsPsychiatryMESH: Ecological Momentary AssessmentResponse rate (survey)MESH: Humansbusiness.industryEcology[SCCO.NEUR]Cognitive science/NeuroscienceMobile ApplicationsMental health030227 psychiatryClinical PracticePsychiatry and Mental healthClinical PsychologyMESH: Students[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthFeasibility StudiesSmartphoneMESH: Mobile ApplicationsMESH: Feasibility Studiesbusiness030217 neurology & neurosurgeryJournal of Affective Disorders
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Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: Study protocol for a pilot randomized controlled trial, the PROT…

2018

Background Adding cyclic short sustained inflations (sigh) to assisted ventilation yields optimizes lung recruitment, decreases heterogeneity and reduces inspiratory effort in patients with acute hypoxemic respiratory failure (AHRF). These findings suggest that adding sigh to pressure support ventilation (PSV) might decrease the risk of lung injury, shorten weaning and improve clinical outcomes. Thus, we conceived a pilot trial to test the feasibility of adding sigh to PSV (the PROTECTION study). Methods PROTECTION is an international randomized controlled trial that will be conducted in 23 intensive care units (ICUs). Patients with AHRF who have been intubated from 24 h to 7 days and under…

procedurePressure supportTime Factorsgenetic structuresbreathingmedicine.medical_treatmentMedicine (miscellaneous)Pilot Projects[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractintensive care unitlaw.inventionPositive-Pressure RespirationStudy Protocol0302 clinical medicineMechanical ventilationRandomized controlled triallawtime factorClinical endpointpatient safetyMulticenter Studies as TopicPharmacology (medical)030212 general & internal medicinerandomized controlled trial (topic)Intervention study; Mechanical ventilation; Positive-pressure ventilation; Pressure support; Recruitment; Sigh; Ventilator-induced lung injury; Weaning; Feasibility Studies; Humans; Hypoxia; Intubation Intratracheal; Lung; Multicenter Studies as Topic; Pilot Projects; Positive-Pressure Respiration; Recovery of Function; Respiratory Insufficiency; Time Factors; Treatment Outcome; Randomized Controlled Trials as Topic; Medicine (miscellaneous); Pharmacology (medical)HypoxiaLungpathophysiologyendotracheal intubationRandomized Controlled Trials as TopicVentilator-induced lung injurylcsh:R5-920Intervention studyadultpilot studyfeasibility studytreatment outcome Feasibility Studie3. Good healthTreatment OutcomeAnesthesiapositive end expiratory pressureBreathingmulticenter study (topic)oxygenationRecruitmentlcsh:Medicine (General)Respiratory Insufficiencyrespiratory tract intubationcirculatory and respiratory physiologyHumanextubationPressure support ventilationWeaningLung injuryArticleSpontaneous breathing trialNO03 medical and health sciencesIntensive care[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]medicineIntubation IntratrachealHumanscontrolled studyPilot ProjectSightreatment failureMechanical ventilationhypoxemiapressure support ventilationtreatment durationbusiness.industrylung inflationrespiratory failureconvalescenceRecovery of Functionmajor clinical studymortalitywater acute respiratory failurehospital dischargeIntratracheal030228 respiratory systemrandomized controlled trialFeasibility StudiesbusinessPositive-pressure ventilationIntubationclinical protocol
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