Search results for " First"

showing 10 items of 329 documents

Endoscopic hemostasis followed by preventive transarterial embolization in high-risk patients with bleeding peptic ulcer: 5-year experience

2019

Abstract Background Upper gastrointestinal bleeding (UGIB) due to peptic ulcer disease is one of the leading causes of death in patients with non-variceal bleeding, resulting in up to 10% mortality rate, and the patient group at high risk of rebleeding (Forrest IA, IB, and IIA) often requires additional therapy after endoscopic hemostasis. Preventive transarterial embolization (P-TAE) after endoscopic hemostasis was introduced in our institution in 2014. The aim of the study is an assessment of the intermediate results of P-TAE following primary endoscopic hemostasis in patients with serious comorbid conditions and high risk of rebleeding. Methods During the period from 2014 to 2018, a tota…

Malemedicine.medical_specialtyLeft gastric arteryTransarterial embolizationmedicine.medical_treatmentlcsh:SurgeryNon-variceal gastrointestinal bleeding030230 surgeryGastroduodenal artery03 medical and health sciences0302 clinical medicineRecurrencePreventivemedicine.arterymedicineHumansEmbolizationAgedAged 80 and overbusiness.industryMortality rateHemostasis Endoscopiclcsh:Medical emergencies. Critical care. Intensive care. First aidlcsh:RD1-811lcsh:RC86-88.9Middle Agedmedicine.diseaseEmbolization TherapeuticSurgeryPeptic Ulcer HemorrhageTreatment OutcomeEmergency MedicineFemale030211 gastroenterology & hepatologySurgeryFresh frozen plasmaUpper gastrointestinal bleedingPacked red blood cellsRockall scorebusinessResearch ArticleWorld Journal of Emergency Surgery
researchProduct

Identification of calcium sensing receptor (CaSR) mRNA-expressing cells in normal and injured rat brain

2009

Calcium sensing receptor (CaSR), isolated for the first time from bovine and human parathyroid, is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expr…

Malemedicine.medical_specialtyTime FactorsCentral nervous systemHippocampusCell CountSettore BIO/11 - Biologia MolecolareBiologySettore BIO/09 - Fisiologiachemistry.chemical_compoundSeizuresInternal medicineSettore BIO/10 - BiochimicaCaSRmedicineAnimalsRNA MessengerRats WistarIbotenic AcidMolecular BiologyIn Situ HybridizationNeuronsKainic AcidGeneral NeuroscienceDentate gyrusBrainColocalizationImmunohistochemistryRatsOligodendrogliamedicine.anatomical_structureEndocrinologynervous systemchemistryBrain InjuriesNeurogliaNeurology (clinical)Pyramidal cellCaSR; BrainCalcium sensing receptor (CaSR) isolated for the first time from bovine and human parathyroid is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expression in neurons and oligodendrocytes whereas it was not found expressed both in the microglia and in astrocytes. One week after kainate-induced seizure CaSR was found in the injured CA3 region of the hippocampus and very interestingly it was found up-regulated in the neurons of CA1-CA2 and dentate gyrus. Similarly 1 week following ibotenic acid injection in the hippocampus CaSR mRNA expression was increased in oligodendrocytes both in the lesioned area and in the contralateral CA1-CA3 pyramidal cell layers and dentate gyrus. One week after needle-induced mechanical lesion an increase of labeled cells expressing CaSR mRNA was observed along the needle track. In conclusion the present results contribute to extend available data on cell type-expressing CaSR in normal and injured brain and could spur to understand the role of CaSR in repairing processes of brain injury.Receptors Calcium-SensingIbotenic acidDevelopmental BiologyAstrocyte
researchProduct

Some approximation properties of ( p , q ) $(p,q)$ -Bernstein operators

2016

This paper is concerned with the $(p,q)$ -analog of Bernstein operators. It is proved that, when the function is convex, the $(p,q)$ -Bernstein operators are monotonic decreasing, as in the classical case. Also, some numerical examples based on Maple algorithms that verify these properties are considered. A global approximation theorem by means of the Ditzian-Totik modulus of smoothness and a Voronovskaja type theorem are proved.

MapleDiscrete mathematicsModulus of smoothnesslcsh:MathematicsApplied Mathematics010102 general mathematicsApproximation theoremRegular polygonMonotonic functionFunction (mathematics)Type (model theory)engineering.materialVoronovskaja type theoremlcsh:QA1-93901 natural sciences010101 applied mathematics( p q ) $(pq)$ -Bernstein operatorsengineeringDiscrete Mathematics and Combinatorics0101 mathematics( p q ) $(pq)$ -calculusK-functionalAnalysisMathematicsDitzian-Totik first order modulus of smoothnessJournal of Inequalities and Applications
researchProduct

Daily use of high-potency cannabis is associated with more positive symptoms in first-episode psychosis patients: The EU-GEI case-control study

2021

The work was supported by: Clinician Scientist Medical Research Council fellowship (project reference MR/M008436/1) to MDF; the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South London at King’s College Hospital NHS Foundation Trust to DQ; DFG Heisenberg professorship (no. 389624707) to UR. National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and King’s College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. The EU-GEI Project is funded by t…

Marijuana AbuseIMPACTPoison controlCannabis usecannabis-associated psychosis0302 clinical medicineSCHIZOPHRENIASettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.health care economics and organizationsApplied PsychologyRISKOUTCOMESbiologyHuman factors and ergonomics/dk/atira/pure/subjectarea/asjc/2700/2738psychopathologyCannabis use; cannabis-associated psychosis; first episode psychosis; psychopathology; psychotic experiences; symptom dimensions3. Good healthPsychiatry and Mental healthSchizophreniaHEALTHPsychopathologyPsychosismedicine.medical_specialtyDISORDERSeducationsymptom dimensions03 medical and health sciencesInjury preventionfirst episode psychosismedicineHumanspsychotic experiencesPsychiatryABUSESettore MED/25 - PsichiatriaSUBSTANCE USEMETAANALYSISCannabisbusiness.industryCase-control studyOriginal Articlesmedicine.diseasebiology.organism_classification030227 psychiatrypsychotic experiencePsychotic Disordersfirst episode psychosiCase-Control StudiesONSETGene-Environment Interaction/dk/atira/pure/subjectarea/asjc/3200/3202Cannabisbusinesscannabis-associated psychosi030217 neurology & neurosurgery
researchProduct

Thermo-mechanical analyses and ways of optimization of the helium cooled DEMO First Wall under RCC-MRx rules

2017

Abstract The EUROfusion Consortium develops a design of a fusion power demonstrator plant (DEMO) in the framework of the European “Horizon 2020” innovation and research program. One of the key components in the fusion reactor is the Breeding Blanket (BB) surrounding the plasma, ensuring tritium self-sufficiency, heat removal for conversion into electricity, and neutron shielding. Among the 4 candidates for the DEMO BB, 2 of them use helium as coolant (HCPB, HCLL), and another one (DCLL) uses helium to cool down the First Wall (FW) only. Due to uncertainties regarding the plasma Heat Flux (HF) load the DEMO BB integrated FW will have to cope with, a set of sensitive thermal and stress analys…

Materials scienceRCC-MRxNuclear engineeringchemistry.chemical_elementBlanket01 natural sciences7. Clean energy010305 fluids & plasmasStress (mechanics)[SPI]Engineering Sciences [physics]Materials Science(all)0103 physical sciencesGeneral Materials ScienceCast3M010306 general physicsDEMOHeliumSettore ING-IND/19 - Impianti NucleariCivil and Structural EngineeringSteady stateBreeding BlanketMechanical EngineeringThermo-mechanicFusion powerCoolantFirst WallchemistryCreepHeat fluxNuclear Energy and EngineeringHCLLDEMO; Breeding; Blanket; HCLL; RCC-MRx; Thermo-mechanics; Cast3M; First WallMaterials Science (all)
researchProduct

Optimal Paths on Urban Networks Using Travelling Times Prevision

2012

We deal with an algorithm that, once origin and destination are fixed, individuates the route that permits to reach the destination in the shortest time, respecting an assigned maximal travel time, and with risks measure below a given threshold. A fluid dynamic model for road networks, according to initial car densities on roads and traffic coefficients at junctions, forecasts the future traffic evolution, giving dynamical weights to a constrained 𝐾 shortest path algorithm. Simulations are performed on a case study to test the efficiency of the proposed procedure.

Mathematical optimizationTraffic congestion reconstruction with Kerner's three-phase theoryArticle SubjectComputer scienceFluid dynamic model; K shortest path algorithm; Travelling times previsionGeneral EngineeringTraffic simulationK shortest path algorithmMeasure (mathematics)lcsh:QA75.5-76.95Computer Science ApplicationsTraffic congestionFluid dynamic modelModeling and SimulationShortest path problemComputer Science::Networking and Internet Architecturelcsh:Electronic computers. Computer scienceTravelling times previsionDijkstra's algorithmConstrained Shortest Path FirstSimulationTraffic waveModelling and Simulation in Engineering
researchProduct

Gli aspetti fiscali delle attività di rigenerazione e riuso di beni a fini di interesse generale.

2017

E’ possibile attribuire un riconoscimento, una legittimazione ed una regolamentazione giuridica all'opera prestata dai privati nell'attività di rigenerazione e riuso di beni di interesse comune? La leva fiscale può essere considerata come strumento per favorire lo sviluppo di queste attività? Alla prima domanda possiamo rispondere che il concetto, oggi in evoluzione, di sussidiarietà orizzontale, sembra essere lo strumento più idoneo per inquadrare giuridicamente le azioni di privati cittadini che volontariamente decidono di prendersi cura di beni comuni ai più diversi livelli (beni immobili o mobili concernenti il patrimonio artistico/culturale o, più in generale, fruibili da una collettiv…

May we give legitimacy and a legal shape to citizens' activities directed to regeneration and re-use of goods of common interest? Taxation (i.e. tax expenses) can encourage these activities? We may answer the first question that the evolving concept of the so said “sussidiarietà orizzontale” seems to be the most appropriate tool to give the actions of private citizens directed to take care of common goods (i.e. cultural heritage or goods that can be used by a given community) a legal framework. To answer the second question we have to face the issue concerning the relationship between taxation and “sussidiarietà orizzontale” notably if tax expenses can be considered in any way a developing tool for the latter. This paper aim to face these issues.Settore IUS/12 - Diritto Tributario
researchProduct

Perceived major experiences of discrimination, ethnic group, and risk of psychosis in a six-country case-control study

2021

AbstractBackgroundPerceived discrimination is associated with worse mental health. Few studies have assessed whether perceived discrimination (i) is associated with the risk of psychotic disorders and (ii) contributes to an increased risk among minority ethnic groups relative to the ethnic majority.MethodsWe used data from the European Network of National Schizophrenia Networks Studying Gene-Environment Interactions Work Package 2, a population-based case−control study of incident psychotic disorders in 17 catchment sites across six countries. We calculated odds ratios (OR) and 95% confidence intervals (95% CI) for the associations between perceived discrimination and psychosis using mixed-…

Mediation (statistics)LIFE EVENTSMIGRATIONPopulationEthnic groupLogistic regressionpsychosiOdds03 medical and health sciences0302 clinical medicineMINORIAS ÉTNICASSCHIZOPHRENIAMedicinepsychosisfirst-episodeeducationCase−controlApplied PsychologyTRAUMACase-control discrimination first-episode minority ethnic group multi-country psychosis psychotic disorderFirst episodemulti-countryeducation.field_of_studyminority ethnic groupCONSEQUENCESbusiness.industryAbsolute risk reductionPATHWAYSOdds ratiopsychotic disorderCase-controlMEDIATION ANALYSIS030227 psychiatryPsychiatry and Mental health[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]HEALTHbusinessCHILDHOOD ADVERSITIES030217 neurology & neurosurgeryDemographydiscrimination
researchProduct

New records of amphipod crustaceans along the Israeli Mediterranean coast, including a rare Mediterranean endemic species, Maera schieckei Karaman & …

2020

A survey has been carried out at four Israeli rocky sites to evaluate the diversity of the amphipod fauna on various hard substrates, still scarcely monitored, as potential pabulum for amphipod crustacean species. A survey of shallow rocky reefs along the Mediterranean coast of Israel recovered 28 species and integrated the Amphipoda checklist for the country ofIsrael with 12 newly-recorded species. Such renewed national list includes Maera schieckei Karaman & Ruffo, 1971, a rare species endemic to the Mediterranean Sea, recorded here for the first time from the southern Levant Basin. The species, described from specimens collected in the Tyrrhenian Sea in 1970, has been only record…

Mediterranean climateAmphipodaSouthern LevantArthropodaFaunaRare speciesSettore BIO/05 - ZoologiaMediterranean BasinMaeridaeMediterranean seaLevant SeaMediterranean SeaAnimaliaAmphipodaEndemismMalacostracalcsh:QH301-705.5Ecology Evolution Behavior and SystematicsEcologybiologyEcologyCrustacean amphipodsMedCrustacean amphipods first records endemism Mediterranean Sea Levant Seabiology.organism_classificationHadzioideaMaeraGeographylcsh:Biology (General)endemismMaera schieckeifirst records
researchProduct

Use of cone-beam computed tomography to evaluate root and canal morphology of mandibular first and second molars in Turkish individuals

2013

Objective: The aim of this study was to investigate the root and canal morphology of mandibular first and second molars in a Turkish population by using cone beam computed tomography (CBCT). Study design: CBCT images of mandibular first (n = 823) and second molar (n = 925) teeth from 605 Turkish patients were analyzed. The root canal configurations were classified according to the method of Vertucci. Results: The majority of mandibular molars (95.8% of first molars, 85.4% of second molars) had two separate roots; however, three roots were identified in 2.06% of first molars and 3.45% of second molars. C-shaped canals occurred 0.85% of first molars and 4.1% of second molars. Three canals wer…

MolarAdultMaleCone beam computed tomographyMorphology (linguistics)TurkeyRoot canalDentistryOdontologíaMandibleMandibular first molarEndodonticsMandibular second molarstomatognathic systemmedicineHumansTooth RootGeneral DentistryRetrospective StudiesOrthodonticsDental Pulp Cavitybusiness.industryMandibleCone-Beam Computed Tomography:CIENCIAS MÉDICAS [UNESCO]MolarCiencias de la saludstomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryResearch-ArticleFemalesense organsDental Pulp Cavitybusiness
researchProduct