Search results for " Fourier"

showing 10 items of 478 documents

DFT studies on armchair (5, 5) SWCNT functionalization. Modification of selected structural and spectroscopic parameters upon two-atom molecule attac…

2015

Abstract Density functional theory (DFT) studies on adsorption of several gaseous homo- and hetero-diatomic molecules (AB) including H2, O2, N2, NO and CO on external surface of H-capped pristine armchair (5, 5) single-walled carbon nanotube (SWCNT) were conducted. Structures of C70H10 and the corresponding C70H10–AB adducts were fully optimized at the B3LYP/6-311G* level of theory. Calculated HOMO/LUMO energy gaps (Eg), 13C NMR chemical shifts and IR/Raman parameters were analyzed and critically compared with available experimental data. Significant changes of carbon NMR atom chemical shifts (up to −100 ppm) and shielding anisotropies (up to −180 ppm) at sites of addition were observed. Fu…

Models MolecularNanotubeMaterials scienceMagnetic Resonance SpectroscopyIR/RamanMolecular ConformationElectrons02 engineering and technologyCarbon nanotube010402 general chemistrySpectrum Analysis Raman01 natural scienceslaw.inventionsymbols.namesakeComputational chemistrylawSpectroscopy Fourier Transform InfraredMaterials ChemistryMoleculeDFT and GIAO NMRHOMO/LUMO gapPhysical and Theoretical ChemistryHOMO/LUMOSpectroscopyNanotubes CarbonChemical shiftsingle-walled karbon nanotube (SWCNT)Carbon-13 NMR021001 nanoscience & nanotechnologyComputer Graphics and Computer-Aided Design0104 chemical sciencessymbolsPhysical chemistryQuantum TheoryThermodynamicsDensity functional theory0210 nano-technologyRaman spectroscopyabsorptionJournal of Molecular Graphics and Modelling
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On the molecular structure of human neuroserpin polymers

2012

The polymerization of serpins is at the root of a large class of diseases; the molecular structure of serpin polymers has been recently debated. In this work, we study the polymerization kinetics of human neuroserpin by Fourier Transform Infra Red spectroscopy and by time-lapse Size Exclusion Chromatography. First, we show that two distinct neuroserpin polymers, formed at 45 and 85°C, display the same isosbestic points in the Amide I' band, and therefore share common secondary structure features. We also find a concentration independent polymerization rate at 45°C suggesting that the polymerization rate-limiting step is the formation of an activated monomeric species. The polymer structures…

Models MolecularSize-exclusion chromatographySerpinBiochemistryProtein Structure Secondaryserpinopathieprotein aggregationchemistry.chemical_compoundStructural BiologyNeuroserpinCatalytic DomainSpectroscopy Fourier Transform InfraredPolymer chemistryHumansMolecular BiologyProtein secondary structureSerpinschemistry.chemical_classificationIsosbestic pointChemistryNeuropeptidesserpinPolymerSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)KineticsCrystallographyMonomerprotein aggregation; serpins; serpinopathies; serpin polymerization; FTIRPolymerizationFTIRChromatography GelProtein Multimerizationserpin polymerization
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Conformational investigation of ?,?-dehydropeptides.N-acetyl-(E)-dehydrophenylalanineN?-methylamide: conformational properties from infrared and theo…

2005

N-Acetyl-(E)-dehydrophenylalanine N'-methylamide [Ac-(E)-DeltaPhe-NHMe], one of a few representative (E)-alpha,beta-dehydroamino acids, was studied by FTIR in dichloromethane and acetonitrile. To support spectroscopic interpretations and to gain some deeper insight into the Ac-(E)-DeltaPhe-NHMe molecule, the Ramachandran potential energy surface was calculated by the B3LYP/6-31G*//HF/3-21G method and the conformers localized were fully optimized at the B3LYP/6-31 + G** level. The spectra and calculations were compared with those of the related molecules Ac-DeltaAla-NHMe and Ac-(Z)-DeltaPhe-NHMe. The title compound assumes two conformational states in equilibrium in dichloromethane solution …

Models MolecularStereochemistryPhenylalanineMolecular ConformationRing (chemistry)Biochemistrychemistry.chemical_compoundStructural BiologySpectroscopy Fourier Transform InfraredDrug DiscoveryMoleculeAcetonitrileMolecular BiologyConformational isomerismPharmacologyMethylene ChlorideHydrogen bondOrganic ChemistryHydrogen BondingGeneral MedicineMethylamideSolutionschemistryPotential energy surfaceThermodynamicsMolecular MedicineRamachandran plotJournal of Peptide Science
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The Molecular and Crystal Structure of tert-Butyl N.ALPHA.-tert-Butoxycarbonyl-L-(S-trityl)cysteinate and the Conformation-Stabilizing Function of We…

2001

The title compound, C31H37NO4S [systematic name: (R)-tert-butyl-2-[(tert-butoxycarbonyl)amino]-3-(tritylsulfanyl)propanoate] is an L-cysteine derivative with three functions: NH2, COOH and SH, blocked by protecting groups tert-butoxycarbonyl, tert-butyl and trityl, respectively. The main chain of the molecule adopts the extended, nearly all-trans C5 conformation with the intramolecular N-H...O=C hydrogen bond. The urethane group is not involved in any intermolecular hydrogen bonding. Only weak intermolecular hydrogen bonds and hydrophobic contacts are observed in the crystal structure. These are C-H...O hydrogen bonds and CH/pi interactions with donor...acceptor distances, C...O ca. 3.5 A a…

Models MolecularStereochemistryPopulationMolecular ConformationCrystallography X-RayRing (chemistry)chemistry.chemical_compoundSpectroscopy Fourier Transform InfraredDrug DiscoveryMoleculeCysteineC5 conformationWeak hydrogen bondseducationConformational isomerismeducation.field_of_studyS-tritylcysteineChemistryHydrogen bondCrystal structureIntermolecular forceHydrogen BondingGeneral ChemistryGeneral MedicineFTIR spectroscopyIntramolecular forceIndicators and ReagentsGasesAb initio calculationsMethyl groupChemical and Pharmaceutical Bulletin
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Complexes of Glycolic Acid with Nitrogen Isolated in Argon Matrices. II. Vibrational Overtone Excitations

2019

Structural changes of glycolic acid (GA) complex with nitrogen induced by selective overtone excitation of the &nu

Models Molecularhydrogen bondMolecular StructureNitrogentechnology industry and agriculturematrix isolationVibrationcomputational chemistryArticlevibrational spectroscopyGlycolateslcsh:QD241-441lcsh:Organic chemistrySpectroscopy Fourier Transform Infraredvibrational overtonesense organscarboxylic acidArgonskin and connective tissue diseasesMolecules
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Structural and Molecular Characterization of meso-Substituted Zinc Porphyrins: A DFT Supported Study

2011

Structural parameters of a range of over 100 meso-substituted zinc porphyrins were reviewed and compared to show how far the nature of the functional group may affect the interatomic distances and bond angles within the porphyrin core. It was proved that even despite evident deformations of the molecular structure, involving twisting of the porphyrin's central plane, the coupled π-bonding system remains flexible and stable. DFT calculations were applied to a number of selected porphyrins representative for the reviewed compounds to emphasize the relevance of theoretical methods in structural investigations of complex macrocyclic molecular systems. Experimental and DFT-simulated IR spectral …

Models Molecularzinc porphyrins; molecular structure; DFT theoretical calculations; IR spectraPorphyrinsSpectrophotometry InfraredStereochemistrySurface PropertiesPharmaceutical Sciencechemistry.chemical_elementInfrared spectroscopyContext (language use)molecular structureZincCrystallography X-RayVibrationArticleAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundDFT theoretical calculationslcsh:Organic chemistryComputational chemistryDrug Discoveryzinc porphyrins molecular structure DFT theoretical calculations IR spectraSpectroscopy Fourier Transform InfraredMoleculeMoietyComputer SimulationPyrrolesPhysical and Theoretical ChemistryIR spectraOrganic ChemistryPorphyrinzinc porphyrinsZincMolecular geometrychemistryModels ChemicalChemistry (miscellaneous)Functional groupMicroscopy Electron ScanningMolecular MedicineQuantum TheoryMolecules
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On Fourier integral operators with Hölder-continuous phase

2018

We study continuity properties in Lebesgue spaces for a class of Fourier integral operators arising in the study of the Boltzmann equation. The phase has a H\"older-type singularity at the origin. We prove boundedness in $L^1$ with a precise loss of decay depending on the H\"older exponent, and we show by counterexamples that a loss occurs even in the case of smooth phases. The results can be seen as a quantitative version of the Beurling-Helson theorem for changes of variables with a H\"older singularity at the origin. The continuity in $L^2$ is studied as well by providing sufficient conditions and relevant counterexamples. The proofs rely on techniques from Time-frequency Analysis.

Modulation spaceApplied Mathematics010102 general mathematicsMathematical analysisShort-time Fourier transformPhase (waves)Hölder conditionFourier integral operators; modulation spaces; short-time Fourier transform; Analysis; Applied Mathematics01 natural sciencesBoltzmann equationFourier integral operatorMathematics - Functional Analysis010101 applied mathematicsSingularityshort-time Fourier transformFourier integral operators0101 mathematicsLp spacemodulation spacesMathematical PhysicsAnalysisMathematics
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Enzyme-accelerated and structure-guided crystallization of calcium carbonate: Role of the carbonic anhydrase in the homologous system

2014

Abstract The calcareous spicules from sponges, e.g. from Sycon raphanus, are composed of almost pure calcium carbonate. In order to elucidate the formation of those structural skeletal elements, the function of the enzyme carbonic anhydrase (CA), isolated from this species, during the in vitro calcium carbonate-based spicule formation, was investigated. It is shown that the recombinant sponge CA substantially accelerates calcium carbonate formation in the in vitro diffusion assay. A stoichiometric calculation revealed that the turnover rate of the sponge CA during the calcification process amounts to 25 CO2 s−1 × molecule CA−1. During this enzymatically driven process, initially pat-like pa…

Molecular Sequence DataInorganic chemistryBiomedical Engineeringchemistry.chemical_elementCalciumBiochemistryCalcium Carbonatelaw.inventionBiomaterialschemistry.chemical_compoundSponge spiculelawSpectroscopy Fourier Transform InfraredAnimalsAmino Acid SequenceSycon raphanusCrystallizationMolecular BiologyCarbonic AnhydrasesMineralsbiologyGeneral MedicineElementsbiology.organism_classificationPoriferaCrystallographySpongeCalcium carbonatechemistryCrystallizationCalcareousBiotechnologyBiomineralizationActa Biomaterialia
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Vibrational analysis of iron and zinc phosphate conversion coating constituents

2001

Abstract The FT-MIR/FT-FIR and NIR-FT-Raman spectra of orthorhombic α -Zn 3 (PO 4 ) 2 ·4H 2 O (α-hopeite) and monoclinic Zn 2 Fe(PO 4 ) 2 ·4H 2 O (phosphophyllite), including deuterated samples, have been measured in the polycrystalline state at room temperature and below. The distribution of vibrational levels was related to the results of complete unit-cell group analyses. The number of uncoupled OD stretching modes of α-hopeite (isotopically dilute samples) strongly exceeds that expected from the number of hydrogen positions of the structure reported. In contrast, unequivocal assignment of the four hydrogen bonds of phosphophyllite has been performed. The distortion of the phosphate tetr…

Molecular StructureHydrogenHydrogen bondAnalytical chemistryZinc phosphatechemistry.chemical_elementHydrogen BondingSpectrum Analysis RamanPhosphateAtomic and Molecular Physics and OpticsPhosphatesAnalytical Chemistrychemistry.chemical_compoundchemistryDeuteriumZinc CompoundsSpectroscopy Fourier Transform InfraredOrthorhombic crystal systemFerrous CompoundsCrystalliteCrystallizationInstrumentationSpectroscopyMonoclinic crystal systemSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
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Synthesis, structure and properties of N-acetylated derivatives of methyl 5-amino-1H-[1,2,4]triazole-3-carboxylate.

2004

Methyl 5-amino-1H-[1,2,4]triazole-3-carboxylate hydrochloride (1). and free ester (2). were obtained and 2 was reacted with Ac(2)O to give the acetylated products 3-6. Compounds 1-6 were studied using HPLC, GC-MS, FTIR and multinuclear NMR spectroscopy, including the cross-polarisation magic angle spinning (CPMAS) technique. The results of the acetylation of 2 were compared to those of the acetylation of 5-amino-1H-[1,2,4]triazole, and for 2 a significant decrease in the susceptibility to acetylation was found. The reaction of 2 with Ac(2)O at 20 degrees C, regardless of the amount and the concentration of the latter, including neat Ac(2)O, proceeds fully regioselectively and leads to one p…

Molecular StructureStereochemistryHydrochlorideTriazole124-TriazoleAcetylationEstersGeneral ChemistryGeneral MedicineNuclear magnetic resonance spectroscopyTriazolesMedicinal chemistryGas Chromatography-Mass SpectrometryAcylationchemistry.chemical_compoundHydrolysischemistryAcetylationDrug DiscoverySpectroscopy Fourier Transform InfraredMagic angle spinningCarboxylateChromatography High Pressure LiquidChemicalpharmaceutical bulletin
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