Search results for " Functional"

showing 10 items of 1811 documents

On Limits at Infinity of Weighted Sobolev Functions

2022

We study necessary and sufficient conditions for a Muckenhoupt weight $w \in L^1_{\mathrm{loc}}(\mathbb R^d)$ that yield almost sure existence of radial, and vertical, limits at infinity for Sobolev functions $u \in W^{1,p}_{\mathrm{loc}}(\mathbb R^d,w)$ with a $p$-integrable gradient $|\nabla u|\in L^p(\mathbb R^d,w)$. The question is shown to subtly depend on the sense in which the limit is taken. First, we fully characterize the existence of radial limits. Second, we give essentially sharp sufficient conditions for the existence of vertical limits. In the specific setting of product and radial weights, we give if and only if statements. These generalize and give new proofs for results of…

matematiikkaMetric Geometry (math.MG)46E36 (46E30 26B35 42B35)MuckenhouptFunctional Analysis (math.FA)Mathematics - Functional AnalysisSobolevMathematics - Analysis of PDEsMathematics - Metric GeometryFOS: MathematicsAsymptoticSobolev functionsLimitdifferentiaaliyhtälötfunktiotAnalysisAnalysis of PDEs (math.AP)
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Effect of a HIIT protocol on the lower limb muscle power, ankle dorsiflexion and dynamic balance in a sedentary type 1 diabetes mellitus population: …

2020

Background Type 1 diabetes mellitus (T1DM) is commonly associated with premature loss of muscle function, ankle dorsiflexion and dynamic balance. Those impairments, usually, lead to physical functionality deterioration. High-intensity interval training is an efficient and safety methodology since it prevents hypoglycemia and not requires much time, which are the main barriers for this population to practice exercise and increase physical conditioning. We hypothesized that a 6-week HIIT program performed on a cycle ergometer would increase lower limb muscle power, ankle dorsiflexion range of motion and dynamic balance without hypoglycemic situations. Methods A total of 19 diagnosed T1DM sub…

medicine.medical_specialtyActivities of daily livingAnatomy and PhysiologyPopulation030209 endocrinology & metabolismSquatPhysical functionalitymedicine.disease_causeGeneral Biochemistry Genetics and Molecular BiologyInterval trainingWeight-bearingHigh-intensity training03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationmedicineeducationDynamic balanceLead (electronics)Exerciseeducation.field_of_studybusiness.industryGeneral Neuroscience030229 sport sciencesGeneral MedicineKinesiologyDiabetes and EndocrinologyType 1 diabetesGeneral Agricultural and Biological SciencesbusinessRange of motionPeerJ
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Constipation severity is associated with productivity losses and healthcare utilization in patients with chronic constipation

2014

OBJECTIVE: We sought to evaluate the association between constipation severity, productivity losses and healthcare utilization in a national sample of Italian patients with chronic non-organic constipation (CC). METHODS: We enrolled 878 outpatients with CC. Clinical and demographic data were collected by physicians during clinical examinations. Patients completed a self-administered questionnaire (Patient Assessment of Constipation-Symptoms, PAC-SYM; Work Productivity and Activity Impairment; healthcare utilization, and Symptoms Checklist 90 Revised - Somatization Scale, SCL-90 R). RESULTS: Mean PAC-SYM score was 1.62 ± 0.69. Mean weekly sick time due to constipation was 2.7 ± 8.6 h and pro…

medicine.medical_specialtyConstipationChronic constipation; Cost-of-illness study; Direct cost; Functional constipation; Healthcare utilization; Indirect cost; Irritable bowel syndrome; Productivity loss; Oncology; Gastroenterologymacromolecular substancesIndirect costsdirect costMedicineIn patientIntensive care medicineProductivitycost-of-illness studyIrritable bowel syndromeirritable bowel syndromeChronic constipation; cost-of-illness study; direct cost; functional constipation; healthcare utilization; indirect cost; irritable bowel syndrome; productivity lossChronic constipationChronic constipationbusiness.industryGastroenterologyhealthcare utilizationfunctional constipationOriginal Articlesmedicine.diseaseproductivity lossOncologyHealthcare utilizationindirect costPhysical therapyFunctional constipationmedicine.symptombusinessUnited European Gastroenterology Journal
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Progression criteria in loading exercise programmes in lower limb tendinopathy: a protocol for a systematic review and meta-analysis

2019

IntroductionLower limb tendinopathies have high rates of incidence and prevalence. Their symptomatology affects the functional capacity of people to exercise and work, being an important cause of economic and social burden. The evidence from the last decades points to therapeutic exercise as the first-line treatment in tendinopathies due to its good short-term and long-term clinical outcomes. However, there is no consensus about how the load progression should be managed throughout the therapeutic exercise programmes.Methods and analysisThis systematic review will be conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The present p…

medicine.medical_specialtyFisioteràpiaPsychological interventionScopusexercise prescriptionPhysical exerciseLower limbRehabilitation Medicine03 medical and health sciences0302 clinical medicineMeta-Analysis as Topicsystematic reviewProtocolHumansMedicine1506patellar tendinopathy030212 general & internal medicine1727Pain Measurementgluteal tendinopathyExercise ToleranceAchilles tendinopathybusiness.industrydoseGeneral MedicinePhysical Functional Performancemedicine.diseaseExercise TherapySystematic reviewLower ExtremityResearch DesignMeta-analysisTendinopathyPhysical therapyTendinopathybusinessExercise prescription030217 neurology & neurosurgerySystematic Reviews as Topic
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Effects of the functional orthopaedic therapy on masticatory muscles activity

2017

Background The purpose of this study was to examine surface electromyographic (sEMG) activity of masticatory muscles before and after functional orthopaedic therapy with Sander appliance. Material and Methods Ten adolescents (5 girls, 5 boys) with an Angle Class II, division I malocclusion, 9-13 years old, were submitted to sEMG before and after functional orthopaedic therapy. To verify the neuromuscular equilibrium, the standardized EMG activities of right and left masseter and anterior temporal muscles were recorded during maximum voluntary clench, and analysed calculating: POC (index of the symmetric distribution of the muscular activity determined by the occlusion); TC (index of presenc…

medicine.medical_specialtyFunctional therapyOrthodonticsElectromyography03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationOcclusionmedicineGeneral DentistrySander appliancemedicine.diagnostic_testbusiness.industryElectromyographyResearch030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Masticatory forceMasticatory musclesUNESCO::CIENCIAS MÉDICASFunctional applianceMalocclusionbusinessMasticatory muscle030217 neurology & neurosurgeryElectromyography; Functional appliance; Masticatory muscles; Sander appliance
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Restoring Neurological Physiology: The Innovative Role of High-Energy MR-Guided Focused Ultrasound (HIMRgFUS). Preliminary Data from a New Method of …

2017

Background Tremor is a disabling condition, common to several neurodegenerative diseases. Lesioning procedures and deep brain stimulation, respectively, of the ventralis intermedius nucleus for intentional tremor, and of the subthalamic nucleus for parkinsonian resting tremor, have been introduced in clinical practice for patients refractory to medical treatment. The combination of high-energy focused ultra-sound (HIFUS) with sophisticated magnetic resonance (MR) instrumentation, together with accurate knowledge of the stereotactic brain coordinates, represents a revolution in neuromodulation. Methods At the Neurosurgical Clinic and the Radiology Department of the University of Palermo,, tw…

medicine.medical_specialtyParkinson's diseaseDeep brain stimulationmedicine.medical_treatmentNeurosurgical ProcedureSeverity of Illness IndexNeurosurgical ProceduresFocused ultrasoundMRI-guided focused ultrasound (MRgFUS)03 medical and health sciences0302 clinical medicineTremormedicineHumans030212 general & internal medicineResting tremorVentral Thalamic Nucleimedicine.diagnostic_testEssential tremorSettore MED/27 - Neurochirurgiabusiness.industryEssential tremor; functional neurosurgery; lesioning surgery; MRI-guided focused ultrasound (MRgFUS); Parkinson’s disease; brain; high-intensity focused ultrasound ablation; humans; magnetic resonance imaging; neurosurgical procedures; severity of illness index; surgery computer-assisted; tremor; ventral thalamic nucleiSettore MED/37 - NeuroradiologiaBrainMagnetic resonance imagingLesioning surgerymedicine.diseaseMagnetic Resonance ImagingNeuromodulation (medicine)nervous system diseasesSurgerySubthalamic nucleusFunctional neurosurgerySurgery Computer-AssistedParkinson’s diseaseEssential tremorHigh-Intensity Focused Ultrasound AblationSettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness030217 neurology & neurosurgeryHuman
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SUBFRACTIONS AND SUBPOPULATIONS OF HDL: AN UPDATE

2014

High-density lipoproteins (HDL) are classified as atheroprotective because they are involved in transport of cholesterol to the liver, known as "reverse cholesterol transport (RCT)" exerting antioxidant and anti-inflammatory activities. There is also evidence for cytoprotective, vasodilatory, antithrombotic, and anti-infectious activities for these lipoproteins. HDLs are known by structural, metabolic and biologic heterogeneity. Thus, different methods are able to distinguish several subclasses of HDL. Different separation techniques appear to support different HDL fractions as being atheroprotective or related with lower cardiovascular (CV) risk. However, HDL particles are not always prote…

medicine.medical_specialtyPharmacologyBiologySystemic inflammationBiochemistrychemistry.chemical_compoundRisk FactorsInternal medicineDrug DiscoveryAntithromboticmedicineAnimalsHumansHdl functionalityPharmacologyCholesterolOrganic ChemistryReverse cholesterol transportBiomarker (cell)EndocrinologychemistryCardiovascular DiseasesMolecular MedicineSeparation methodlipids (amino acids peptides and proteins)Hdl subfractionscardiovascular risk electrophoresis high-density lipoprotein nuclear magnetic resonance proteome subclasses subfractions ultracentrifugation.medicine.symptomLipoproteins HDL
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Muscle Strength and Physical Performance Are Associated with Reaction Time Performance in Older People

2021

Background: Functional mobility and muscle strength are well known risk factors for sarcopenia. Furthermore, possible associations have been suggested between predisposing factors of sarcopenia and reaction time among the elderly. This study aims to analyze possible associations of functional mobility and muscle strength and reaction times in a population of people aged &gt

medicine.medical_specialtySarcopeniaHealth Toxicology and MutagenesisPopulationPhysical fitnessAnciano030209 endocrinology & metabolismPhysical functionelderlyArticlesarcopenia03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationphysical functionReaction TimeMedicineHumans030212 general & internal medicineMuscle StrengtheducationMuscle SkeletalAgededucation.field_of_studyInflamaciónHand Strengthbusiness.industryPublic Health Environmental and Occupational HealthRPhysical Functional Performancemusculoskeletal systemmedicine.diseaseConfidence intervalCross-Sectional StudiesPhysical performanceNutriciónSarcopeniaMuscle strengthphysical fitnessreaction timesMedicinebusinessOlder peopleDesarrollo fisiológicohuman activitiesInternational Journal of Environmental Research and Public Health
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Lomitapide treatment highly affects lipoprotein profile and HDL functionality in patients with familial hypercholesterolemia

2015

medicine.medical_specialtybusiness.industryFamilial hypercholesterolemiamedicine.diseaseLomitapidechemistry.chemical_compoundEndocrinologychemistryInternal medicinemedicineIn patientHdl functionalityCardiology and Cardiovascular MedicinebusinessLipoproteinAtherosclerosis
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Long-term clinical and radiological outcomes following anterior cervical discectomy and fusion by zero-profile anchored cage

2018

Objectives: The purpose of this study was to extend the results of our previous study providing a minimum of 4-year follow-up results of a prospective study following implantation of a cervical cage with an integrated fixation system. Summary of Background Data: The use of cervical intersomatic cages with an integrated fixation system for anterior cervical discectomy and fusion (ACDF) has increased rapidly in this last decade. In addition to immediate stabilization, these implants allow avoidance of anterior plating and iliac crest bone-grafting. Methods: Patients were studied prospectively, and data were collected and analyzed. Intersomatic cages with an integrated fixation system were use…

medicine.medical_specialtylcsh:Diseases of the musculoskeletal systemVisual analogue scaleAnterior cervical discectomy and fusionIliac crest03 medical and health sciencesFixation (surgical)0302 clinical medicinemedicineProspective cohort studycervical disc herniation030222 orthopedicsCobb anglebusiness.industryAnterior cervical discectomy fusionSurgerymedicine.anatomical_structurecervical spondylosis functional scoresOrthopedic surgeryOriginal ArticleSurgeryNeurology (clinical)Implantlcsh:RC925-935business030217 neurology & neurosurgeryJournal of Craniovertebral Junction and Spine
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