Search results for " High pressure liquid"

showing 5 items of 705 documents

Non-Occupational Exposure to Pesticides: Experimental Approaches and Analytical Techniques (from 2019)

2021

© 2021 by the authors.

pesticide residuesNon occupationalenvironmental exposurePharmaceutical ScienceOrganic chemistryReview010501 environmental scienceshuman health01 natural sciencesGas Chromatography-Mass SpectrometryMass SpectrometryAnalytical ChemistryGlobal populationHuman healthQD241-441Environmental healthDrug DiscoveryPlaguicidesHealth Status IndicatorsHumansPesticidesPhysical and Theoretical ChemistrySolvent extractionestimated intakesChromatography High Pressure Liquid0105 earth and related environmental sciencesPesticide residueSolid Phase Extraction010401 analytical chemistryindirect estimationdirect estimationEnvironmental exposureQuímicaPesticide0104 chemical scienceswastewater-based epidemiologyChemistry (miscellaneous)Human exposureSolventsMolecular MedicineEnvironmental scienceMolecules
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Degradation of an alkaloid pheromone from the pale-brown chafer, Phyllopertha diversa (Coleoptera: Scarabaeidae), by an insect olfactory cytochrome P…

1999

AbstractThe pale-brown chafer, Phyllopertha diversa, utilizes an unusual alkaloid, 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione, as its sex pheromone. This compound is rapidly degraded in vitro by the antennal protein extracts from this scarab beetle. Demethylation at the N-1 position and hydroxylation of the aromatic ring have been identified as the major catabolic pathways. The enzyme responsible for the pheromone degradation is membrane-bound, requires NAD(P)H for activity and is sensitive to cytochrome P450 inhibitors, such as proadifen and metyrapone. The ability to metabolize this unusual pheromone was not detected in 12 species tested, indicating that the P450 system, specific to male P…

pheromone-degrading enzymemedia_common.quotation_subjectBiophysicsInsectOlfactionscarab beetleBiochemistryMass SpectrometryHydroxylationchemistry.chemical_compoundAlkaloidsCytochrome P-450 Enzyme SystemStructural BiologyMicrosomesBotanyGeneticsAnimalsCytochrome P-450 Enzyme InhibitorsEnzyme InhibitorsSex AttractantsMolecular BiologyChromatography High Pressure LiquidDemethylationmedia_commonbiologyMolecular StructureProadifenCytochrome P450Cell BiologyMetyraponeProadifenColeopteraBiochemistrychemistrySex pheromonebiology.proteinQuinazolinesPheromoneInsect ProteinsChromatography Thin Layerpheromone inactivationolfactionFEBS letters
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Low levels of both xanthine dehydrogenase and of cellular retinol binding protein are responsible for retinoic acid deficiency in malignant human mam…

2009

The seeming impairment of retinoid metabolism in human breast tumor cells has been attributed to the lower expression of cellular retinol binding proteins (CRBPs), of alcohol/retinol dehydrogenases, or aldehyde/retinaldehyde dehydrogenases. In a previous study we indicated that xanthine dehydrogenase (XDH) is able to oxidize actively both all-trans-retinol (t-ROL) bound to the CRBP (holo-CRBP) and all-trans-retinaldehyde (t-RAL) to all-trans-retinoic acid (t-RA) in human mammary epithelial cells (HMEC). Since both XDH and CRBP are required for the biosynthesis of t-RA, we have inspected their bioavailability in both estrogen-responsive and nonresponsive human mammary epithelial cancer cells…

retinoic acid biosynthesis tumor mammary cellsXanthine DehydrogenaseCellular differentiationRetinoic acidBreast NeoplasmsTretinoinBiologyGeneral Biochemistry Genetics and Molecular BiologyCell Linechemistry.chemical_compoundHistory and Philosophy of ScienceBiosynthesisCell Line TumorSettore BIO/10 - BiochimicaHumansMammary Glands HumanRadiometryChromatography High Pressure LiquidGeneral NeuroscienceRetinolRetinol-Binding Proteins CellularMolecular biologyRetinol binding proteinBiochemistrychemistryXanthine dehydrogenaseCell cultureCancer cell
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Evaluation of the Behavior of Phenolic Compounds and Steviol Glycosides of Sonicated Strawberry Juice Sweetened with Stevia (Stevia rebaudiana Berton…

2019

In this study, the influence of stevia addition and sonication processing parameters on the phenolic content and profile as well as the steviol glycosides of strawberry juice-based samples was investigated. For this purpose, three matrices&mdash

sonicationSonicationgreen stevia powder ; strawberry juice ; antioxidant compounds ; steviol glycosides ; sonicationPharmaceutical ScienceSteviol01 natural sciencesFragariaArticleAntioxidantsAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistryantioxidant compoundsGlucosidesPhenolsDrug DiscoveryFood scienceSteviosidePhysical and Theoretical Chemistrysteviol glycosidesstrawberry juiceChromatography High Pressure Liquidchemistry.chemical_classificationFlavonoidsbiologyPlant Extracts010401 analytical chemistryOrganic ChemistryGlycoside04 agricultural and veterinary sciencesSweetnessgreen stevia powderbiology.organism_classification040401 food scienceStevia0104 chemical sciencesStevia rebaudianachemistryChemistry (miscellaneous)Molecular MedicineKaempferolDiterpenes KauraneMolecules
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Determination of glyphosate and its metabolite aminomethylphosphonic acid in fruit juices using supported-liquid membrane preconcentration method wit…

2005

Abstract The application of supported-liquid membrane (SLM) technique for effective extraction of N -(phosphonomethyl)glycine (glyphosate) and its primary metabolite aminomethylphosphonic acid (AMPA) from juices (orange, grapefruit, apple and blackcurrant) in combination with HPLC-UV detection after derivatization with p -toluenesulphonyl chloride (TsCl) is presented. The influence of various parameters such as the composition of acceptor phase, flow-rate, concentration of analytes, on the performance of extraction procedure, was studied. It was shown that by appropriate manipulation of SLM parameters the level of detection could be significantly improved. The influence of SLM conditions on…

supported-liquid membrane extractionMetaboliteGlycineOrganophosphonatesTetrazolesaminomethylphosphonic acidfruit juiceBiochemistryHigh-performance liquid chromatographyChlorideAnalytical ChemistryBeveragesTosyl Compoundschemistry.chemical_compoundglyphosatemedicineSample preparationAminomethylphosphonic acidDerivatizationChromatography High Pressure LiquidChromatographyOrganic ChemistryPrimary metaboliteMembranes ArtificialIsoxazolespesticidesGeneral MedicinechemistryFruitGlyphosateCalibrationSpectrophotometry UltravioletHPLCmedicine.drugJournal of Chromatography A
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