Search results for " Humans"
showing 10 items of 2466 documents
Multidrug and broad-spectrum cephalosporin resistance among Salmonella enterica serotype enteritidis clinical isolates in southern Italy.
2002
ABSTRACT From 1992 to 1997, only six sporadic isolates of Salmonella enterica serotype Enteritidis from patients with cases of gastroenteritis in southern Italy exhibited resistance to broad-spectrum cephalosporins. Five isolates produced SHV-12, and one isolate encoded a class C β-lactamase. The bla SHV-12 gene was located in at least two different self-transferable plasmids, one of which also carried a novel class 1 integron.
The socio-ecology of zoonotic infections
2011
The resurgence of infectious diseases of zoonotic origin observed in recent years imposes a major morbidity/mortality burden worldwide, and also a major economic burden that extends beyond pure medical costs. The resurgence and epidemiology of zoonoses are complex and dynamic, being influenced by varying parameters that can roughly be categorized as human-related, pathogen-related, and climate/environment-related; however, there is significant interplay between these factors. Human-related factors include modern life trends such as ecotourism, increased exposure through hunting or pet owning, and culinary habits, industrialization sequelae such as farming/food chain intensification, globali…
Current and future challenges in HCV: insights from an Italian experts panel
2017
Background: The recent availability of direct acting antiviral drugs (DAAs) has drastically changed hepatitis C virus (HCV) treatment scenarios, due to the exceedingly high rates of sustained virological response (SVR) and excellent tolerability allowing for treatment at all disease stages. Methods: A panel of Italian experts was convened twice, in November 2016 and January 2017, to provide further support on some open issues and provide guidance for personalized HCV care, also in light of forthcoming regimens. Results and conclusions: Treatment recommendations issued by international and national liver societies to guide clinicians in the management of HCV infection are constantly updated …
El Derecho internacional de las migraciones: entre la crisis y la renovación
2019
The international migration regime currently in force is manifestly insufficient for the regulation and governance of migration flows. The irreducible collision between the right of persons to leave their country and the right of States to reject the admission of migrants in its territory has led, in practice, to a vicious circle resulting in an increase in irregular migration and the multiplication of dramatic situations that hurt humanitarian feelings. In view of this situation, the United Nations promoted the adoption in January of 2019 of two instruments seeking to establish a new framework for international cooperation in this field: a Global Compact on Refugees and a Global Compact on…
Nile Red lifetime reveals microplastic identity
2020
Microplastic pollution is recognized as a worldwide environmental problem. The increasing daily use and release of plastics into the environment have led to the accumulation of fragmented microplastics, with potentially awful consequences for the environment, and animal and human health. The detection and identification of microplastics are of utmost importance, but available methods are still limited. In this work, a new approach is presented for the analysis of microplastics based on hydrophobic fluorescence staining with Nile Red, using spectrally resolved confocal fluorescence microscopy and fluorescence lifetime imaging microscopy (FLIM). Significant differences were observed in the em…
The migrant crisis in the Mediterranean Sea: Empirical evidence on policy interventions
2021
Abstract This paper presents a novel set of empirical evidence to explore several hypotheses regarding the migrant crisis in the Mediterranean Sea. The political instability in transit countries, such as Libya, that made pre-existent repatriation policies ineffective, called for several search-and-rescue operations in the Mediterranean, which in turn have been wrongly accused of fostering illegal immigration and increasing deaths at sea. The empirical results show that the main determinants of the departures are several root causes at the departing African countries, underlining the importance of fighting human smuggling networks. The paper suggests a change in migration studies’ perspectiv…
Minerali, piante, animali e uomini: indagine lessicale sul rapporto tra i regni naturali e l’ambiente nella Grecia antica
2021
L’articolo indaga il rapporto che sussiste nella Grecia antica tra la terra e i cosiddetti «regni naturali» (minerale, vegetale, animale, umano) alla luce del lessico utilizzato per indicarlo e mostra che, a differenza di quanto avviene presso di noi, esso è spesso analogo per tutti e quattro gli ambiti. L’azione della terra (o altri elementi eco-sistemici) nei confronti degli elementi che appartengono ai diversi regni, infatti, è tendenzialmente designata dagli stessi verbi (vengono presi in considerazione phýein, ghennán, bóskein, tréphein, phérein, anadidónai): la terra phýei (e ugualmente possono essere usati anche gli altri verbi) sia uomini, sia animali, sia piante, sia minerali. Th…
Harmful effect of immunotherapy in children with combined snail and mite allergy
2002
Abstract Background: With respect to allergy, the possibility of cross-reactivity between snail and mite is well recognized, and anecdotal reports suggesting that allergen immunotherapy with mite extract can worsen snail-induced allergy exist. Objective: We describe the effect of immunotherapy in 4 children with snail-mite allergy. Methods: Four children (1 boy and 3 girls; 9-13 years of age) had consistent clinical histories (mild immediate respiratory symptoms after ingestion) and positive skin reactions for allergy to snail. They also had mite-induced asthma and were therefore prescribed subcutaneous specific immunotherapy and subsequently followed. Results: Several months (8-25) after s…
A Revised Timescale for Human Evolution Based on Ancient Mitochondrial Genomes
2013
Summary Background Recent analyses of de novo DNA mutations in modern humans have suggested a nuclear substitution rate that is approximately half that of previous estimates based on fossil calibration. This result has led to suggestions that major events in human evolution occurred far earlier than previously thought. Results Here, we use mitochondrial genome sequences from ten securely dated ancient modern humans spanning 40,000 years as calibration points for the mitochondrial clock, thus yielding a direct estimate of the mitochondrial substitution rate. Our clock yields mitochondrial divergence times that are in agreement with earlier estimates based on calibration points derived from e…
A human post-mortem brain model for the standardization of multi-centre MRI studies
2015
Multi-centre MRI studies of the brain are essential for enrolling large and diverse patient cohorts, as required for the investigation of heterogeneous neurological and psychiatric diseases. However, the multi-site comparison of standard MRI data sets that are weighted with respect to tissue parameters such as the relaxation times (T1, T2) and proton density (PD) may be problematic, as signal intensities and image contrasts depend on site-specific details such as the sequences used, imaging parameters, and sensitivity profiles of the radiofrequency (RF) coils. Water or gel phantoms are frequently used for long-term and/or inter-site quality assessment. However, these phantoms hardly mimic t…