Search results for " IA"
showing 10 items of 86 documents
FUNCTIONAL ASSESSMENT OF OLDER PERSONS: ROLE OF COMPREHENSIVE GERIATRIC ASSESSMENT IN GERIATRIC ONCOLOGY
2010
Patterns of Innate or Acquired Resistance to Anticancer Drugs: Our Experience to Overcome It
2021
Drug resistance, which is often of a multiple type, can be defined as the ability of cancer cells to obtain resistance to both conventional and novel chemotherapy agents. It remains a major problem to solve in cancer therapy. The mechanisms of resistance are multifactorial, and in our cellular models of acute myeloid leukemia, hepatocellular carcinoma, and triple-negative breast cancer, it involves the NF-κB pathway. In our opinion, multitarget molecules can be considered as privileged compounds capable of attacking and reversing the resistant phenotype. In the phenomena of both innate and acquired drug resistance that we have been studying since 1998 to today and up to 2016 under the guida…
Immune escape of AKT overexpressing ovarian cancer cells
2012
Platinum-resistance is the most crucial problem for treatment of ovarian cancer. There is a clinical need for new treatment strategies which overcome platinum resistance. As survival is strongly influenced by immunological parameters, immunotherapeutic strategies appear promising. Therefore a better understanding of the interaction between ovarian tumour cells and cells of the immune system is a necessary prerequisite. In the present study we aimed to enlighten the interactions between platinum resistant and platinum sensitive ovarian cancer cells and natural-killer (NK)-cells. Modified FATAL assay was used for determining the killing efficiency of NK-cells for the parental A2780 cells and …
Impact of intra-aortic balloon counterpulsation on all-cause mortality among patients with Takotsubo syndrome complicated by cardiogenic shock: resul…
2023
Abstract Aims Takotsubo syndrome (TTS) is an acute and reversible left ventricular dysfunction and can be complicated by cardiogenic shock (CS). However, few data are available on optimal care in TTS complicated by CS. Aim of this study was to evaluate short- and long-term impact of intra-aortic balloon pumping (IABP) on mortality in this setting. Methods and results In a multi-centre, international registry on TTS, 2248 consecutive patients were enrolled from 38 centres from Germany, Italy, and Spain. Of the 2248 patients, 212 (9.4%) experienced CS. Patients with CS had a higher prevalence of diabetes (27% vs. 19%), male sex (25% vs. 10%), and right ventricular involvement (10% vs. 5%) (P …
Producción de personas, reproducción de representaciones. Reflexiones sobre dos programas de capacitación en liderazgo
2020
The present paper addresses the question of the role Executive Education performs in the strengthening and reproduction of neoliberal ideology. It aims to critically reflect on the way selected contents and teaching activities operate jointly enabling or inhibiting certain perspectives regarding work in organizations. Two Leadership training programs are analyzed in this article, currently delivered by the two most prestigious business schools in Argentina: IAE Business School, and Torcuato Di Tella Business School. I begin with a general description of each one and proceed analyzing their educational proposals. Finally, the critical review reveals their consistency with a set of social rep…
Participating Laboratories. Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and isl…
2008
Designing ecolabels in order to mitigate market failures: an application to agrofood products
2007
For the market for ecofriendly characteristics of agrofood producs effectively, ùeans of mitigationg asymmetric information, informational overload and public goods properties are necessary. Ecolabel success requires a design and an implementation capable of mitigating simultaneously these three sources of market failures. Our contribution differs from many to date by (1) introducing and analyzing the informational overload as a source of market falure and (2) considering the ecolabel, not only as tool to re-establish information summetry between the producer and consumer but also as a way to overcome international overload and public goods problems. We analyze how these sources of market f…
Accumuler le capital humain tout au long de la vie: Quels facteurs prédictifs de la participation à la formation permanente?
2003
This article addresses the main predictors of adult education, using statistical methods different from those generally used by social science researchers. Its aim is twofold. First, it seeks to explain in a simple and comprehensible manner the methodological value of these methods (in relation to the use of structural models); secondly, it demonstrates the concrete usefulness of these methods on the basis of a recent piece of research on the data from the International Adult Literacy Survey (IALS).
Measurements and Observations in the XXI century (MOXXI) : innovation and multi-disciplinarity to sense the hydrological cycle
2018
ISI Document Delivery No.: FV7JXTimes Cited: 4Cited Reference Count: 249Tauro, Flavia Selker, John van de Giesen, Nick Abrate, Tommaso Uijlenhoet, Remko Porfiri, Maurizio Manfreda, Salvatore Caylor, Kelly Moramarco, Tommaso Benveniste, Jerome Ciraolo, Giuseppe Estes, Lyndon Domeneghetti, Alessio Perks, Matthew T. Corbari, Chiara Rabiei, Ehsan Ravazzani, Giovanni Bogena, Heye Harfouche, Antoine Brocca, Luca Maltese, Antonino Wickert, Andy Tarpanelli, Angelica Good, Stephen Alcala, Jose Manuel Lopez Petroselli, Andrea Cudennec, Christophe Blume, Theresa Hut, Rolf Grimaldi, SalvatoreTaylor & francis ltdAbingdon; To promote the advancement of novel observation techniques that may lead to new so…
TRACE Code Analyses for the IAEA ICSP on “Integral PWR Design Natural Circulation Flow Stability and Thermo-Hydraulic Coupling of Containment and Pri…
2011
Considering the world energy demand increase in order to fulfill an environmental and economic sustainability, the energy policy of each country has to diversify the sources of energy and use stable, safe energy production option able of producing electricity in a clean way contributing in cutting the CO2 emission. In the framework of the sustainable development, today the use of advanced nuclear power plant, have an important role in the environmental and economic sustainability of country energy strategy. In the last 20 years, in fact, the international community, taking into account the operational experience of the nuclear reactors, starts the development of new advanced reactor designs…