Search results for " IMA"

Study of bubble size distribution in bubbling fluidized beds via Digital Image Analysis Technique

2008

Fragment‐ and Negative Image‐Based Screening of Phosphodiesterase 10A Inhibitors

2019

A novel virtual screening methodology called fragment‐ and negative image‐based (F‐NiB) screening is introduced and tested experimentally using phosphodiesterase 10A (PDE10A) as a case study. Potent PDE10A‐specific small‐molecule inhibitors are actively sought after for their antipsychotic and neuroprotective effects. The F‐NiB combines features from both fragment‐based drug discovery and negative image‐based (NIB) screening methodologies to facilitate rational drug discovery. The selected structural parts of protein‐bound ligand(s) are seamlessly combined with the negative image of the target's ligand‐binding cavity. This cavity‐ and fragment‐based hybrid model, namely its shape and electr…

'Beyond the Floats of Cloud': The Variable Geometry of the Frostian Sky

2014

International audience; "

On the use of composite indicators for mobile communications network management in smart sustainable cities

2020

Beyond 5G networks will be fundamental towards enabling sustainable mobile communication networks. One of the most challenging scenarios will be met in ultra-dense networks that are deployed in densely populated areas. In this particular case, mobile network operators should benefit from new assessment metrics and data science tools to ensure an effective management of their networks. In fact, incorporating architectures allowing a cognitive network management framework could simplify processes and enhance the network&rsquo

Multispectral filter arrays: Recent advances and practical implementation

2014

Thanks to some technical progress in interferencefilter design based on different technologies, we can finally successfully implement the concept of multispectral filter array-based sensors. This article provides the relevant state-of-the-art for multispectral imaging systems and presents the characteristics of the elements of our multispectral sensor as a case study. The spectral characteristics are based on two different spatial arrangements that distribute eight different bandpass filters in the visible and near-infrared area of the spectrum. We demonstrate that the system is viable and evaluate its performance through sensor spectral simulation. Multispectral filter arrays: Recent advan…

Imagem corporal positiva e redes sociais na população adulta da área metropolitana de Buenos Aires

2021

Resumen: La imagen corporal positiva presenta una función protectora preeminente ante los medios de comunicación actuales, sin embargo, a la fecha no se cuenta con estudios que la vinculen con las redes sociales. El objetivo de este trabajo fue estudiar la asociación entre la motivación y usos de redes sociales y la imagen corporal positiva, considerando diferencias por sexo y grupos de edad. La muestra contó con 180 participantes, 94 varones (52.2 %) y 86 mujeres (47.8 %), edades de 18 a 65 años (M = 31.03; DE = 13.34). Los instrumentos utilizados fueron el BAS-2 y una encuesta sobre redes sociales. La imagen corporal positiva presentó asociación negativa con dos escalas de la motivación p…

Wyobraźnia teoriopolityczna: kilka uwag na marginesie książki "Rebelia i reakcja. Rewolucja 1905 roku i plebejskie doświadczenie polityczne" Wiktora …

2017

Nauki spoeczne, rozumiane jako krytyczne i nieneutralne ze swej natury, winny być wyposażone w określone kompetencje i wrażliwości. C. W. Mills jako taką kompetencję określił wyobraźnię socjologiczną - będącą badaniem nakierowanym na związek historii i biografii, a którą w późniejszym czasie Anthony Giddens zinterpretował jako trzy podstawowe wrażliwości: historyczna, antropologiczna, krytyczna. Przełożeniem na nauki polityczne byłaby wyobraźnia teriopolityczna, na którą składałyby się takie parametry m.in. jak historyczność zjawisk politycznych, antysubstancjalizm, samoświadomość badawcza. Dookreślenie wyobraźni teoriopolitycznej proponuję w kontekście pracy Wiktora Marca "Rebelia i reakcj…

A Method to Extract the Complete Fiber Network Topology of Planar Fibrous Tissues and Scaffolds.

2010

Improving fabrication protocols and design strategies, investigating on how scaffold architecture affects cell morphology, metabolism and phenotypic expression, predicting mechanical behaviors, have increasingly become crucial goals in the development of engineered tissue scaffolds. In the present study, an image-based analysis approach that provides an automatic tool to fully characterize engineered tissues fiber network topology was developed. The following micro architectural features are detected: fiber angle distribution, fiber connectivity, fiber overlap spatial density, fiber diameter. In order to demonstrate the potential of this approach Electrospun poly(ester urethane)urea (ES-PEU…

Shoulder ultrasound: current concepts and future perspectives

2021

Ultrasonography is an established and effective imaging technique that can be used to evaluate articular and periarticular structures around the shoulder. It has been shown to be useful in a wide range of rotator cuff diseases (e.g. tendon tears, rotator cuff calcific tendinopathy and bursitis) as well as non-rotator cuff abnormalities (instability, synovial joint diseases and nerve entrapment syndrome). A scanning protocol is highly recommended to reduce the rate of operators’ errors by following a standardized scheme including a list of main structures. Shoulder ultrasound has several advantages: it is a relatively cheap and widely available technique, free from ionizing radiation, that c…

Cooperative sound design: a protocol analysis

2016

Formal protocol analysis and linkographic representations are well-established approaches in design cognition studies, in the visual domain. We introduce the method and tools in the auditory domain, by analysing a case of collaborative sound design. We show how they can provide relevant qualitative and quantitative information about the efficiency of the creative process.