Search results for " IS"
showing 10 items of 5661 documents
Substituted Dibenzothiophenes I: Synthesis, Chromatography, Mass Spectrometry and Structure Elucidation by1H NMR Spectroscopy
1992
Abstract Some polychlorinated and polymethylated dibenzothiophenes have been synthesized to serve as model compounds in environmental analysis. In order to obtain pure isomers, the synthesis mixtures have been fractionated with reversed-phase high performance liquid chromatography. In spite of a high sensitivity, mass spectrometry does not provide any reliable way to determine the precise structures of different isomers. Therefore, 1H NMR spectroscopy has been utilized as an aid in their analysis. The structures for two isomeric tetramethyldibenzothiophenes could be suggested on the basis of their 1H NMR spectra. Also some proposals for possible structures of two isomeric trimethyldibenzoth…
Concept of Spectrobiopsy Facing Gliomas: Rational and Future Perspectives Related to Target Therapy
2020
Gliomas represent the most common primary intracranial tumors with an estimated incidence of 31% of all central nervous system neoplasms. Lesions originated from glial cells are extremely heterogeneous, ranging from low grade to high grade with different clinical and biological malignancy. Glioblastoma multiforme (GBM) is the most aggressive and frequent primary malignant tumor of the central nervous system in adults. Even though in the past decades considerable efforts have been made in the therapeutic management of this type of tumor,2 the prognosis after diagnosis of GBM remains extremely poor, reaching a median overall survival of 12–18 months. In 2016 the World Health Organization clas…
Magnetic Resonance Spectrobiopsy for Prediction of Isocitrate Dehydrogenase Mutation in Glioma
2020
Despite the existence of multimodal therapy paradigm, high-grade gliomas (HGGs) remain devastating tumors associated with one of the worst prognoses. Glioblastoma (GBM) is the most frequent reported histologic type with a median survival, after surgery and combined treatment with chemotherapy and radiotherapy, ranging from 12 to 16 months. The poor prognosis is due to the lack of therapeutic efficacy of chemical agents and irradiation in hypoxic tumor areas. Experimental studies have investigated several molecules with the aim to counteract several downstream signaling important in tumor progression, unfortunately without conclusive results. Several studies have shown that the extent of res…
Parasite infection alters host stable-isotope composition under controlled feeding
2016
1) Stable isotopes are widely used for studying trophic relationships, but variation driven by environmental conditions or food availability complicates the interpretation of trophic dynamics. Parasites are ubiquitous and known to affect physiological functions of their hosts, but only few studies have assessed the effects of parasites on isotope composition of hosts. 2) We measured the changes in two of the most commonly used stable isotopes in food-web studies, nitrogen (i.e. 15N:14N ratio; denoted as δ15N) and carbon (13C:12C; δ13C) in Daphnia hosts exposed to infection by a parasitic micosporidian in the laboratory. Isotopic signatures of hosts fed a standardised controlled diet were co…
Assessment of allyl isothiocyanate as a fumigant to avoid mycotoxin production during corn storage
2016
The occurrence of fungi and mycotoxins in foods modify sensorial properties and represents a health risk for consumers, and the use of natural antimicrobials may be an alternative to reduce this problem. The objective of this study was evaluate the potential of allyl isothiocyanate (AITC) in inhibit the production of mycotoxins in corn kernels by Aspergillus parasticus, Fusarium tricinctum, Fusarium verticillioides, Alternaria alternata and Gibberela zeae. Kernels were treated with gaseous AITC at 50, 100 or 500 μL/L during 48 h in hermetic flasks. Then, flasks were opened for 24 h and 100 g of corn were inoculated with 105 conidia/g of either fungal species. Flasks were kept at 23 °…
The Dark Side of the Web—A Risk for Children and Adolescents Challenged by Isolation during the Novel Coronavirus 2019 Pandemic
2021
In response to the global novel coronavirus disease 2019 (COVID-19) pandemic, many countries around the world adopted social isolation measures to contain the spread of the virus.1 For children and adolescents, limitations in faceto-face activities and interactions with their traditional peer groups has been a frustrating experience. After disease containment measures, which included school closures, social distancing, and home quarantine, children and adolescents faced a prolonged state of physical isolation from their peers, teachers, extended family, and community networks that affects their emotional and behavioral health.2 Parents and pediatricians are reporting signs of mental distres…
COVID-19 Confinement and Health Risk Behaviors in Spain
2021
The World Health Organization (WHO) has declared a world pandemic due to COVID-19. In response, most affected countries have enacted measures involving compulsory confinement and restrictions on free movement, which likely influence citizens' lifestyles. This study investigates changes in health risk behaviors (HRBs) with duration of confinement. An online cross-sectional survey served to collect data about the Spanish adult population regarding health behaviors during the first 3 weeks of confinement. A large sample of participants (
Cuestiones varias en torno a la determinación de la filiación por doble paternidad
2018
The article 7.3 of the law 14/2006, of May 26 on technologies of human assisted reproduction establishes the possibility of determining legally the double maternity of married women and not separated legally or of fact, when the not biological mother consents that filiation decides to his favor the respect of the born son of his spouse. In the suppositions not regulated in the mentioned rule the Supreme Court in relation with equal women?s homosexuality in judgment of December 5, 2013 and January 15, 2014 applies the civil code and allows to determine judicially the maternity by means of the exercise of an action of claim for possession of status foreseen in the article 131. In the present …
Why reg. (eu) no. 1103/2016 and 1104/2016 impact on the european citizens daily life?
2021
Why families do need the tools and instruments implemented by PSEFS Project? Why this is not an issue for lawyers, judges and University professors only. The answer to this question is that Reg. (EU) no. 1103/2016 and no. 1104/2016 impact on the European citizens daily life. We follow the problems of a young couple in order to have a better understanding and an evidence of this statement.
Cinesiterapia global en la enfermedad arterial periférica
2010
En el caso de la cinesiterapia global indicada en la enfermedad arterial periférica, se incluye el protocolo de marcha a velocidad y/o inclinación programadas. Éste busca incrementar progresivamente la distancia recorrida hasta la aparición de dolor claudicante, y en el se distinguen tres fases diferenciadas: el calentamiento, la pauta de esfuerzo y el enfriamiento.