Search results for " Infection"

Jugular pacing lead extraction with laser sheath: a case report.

2010

Over the past 20 years, the number of patients with pacemakers (PM) or implantable cardioverter defibrillators has risen markedly; consequently, an increasing number of lead-removal procedures have become necessary. A 64-year-old woman presenting with an infected device pocket and positive bacterial cultures ( Staphylococcus aureus ) was admitted to our department for lead removal; in 1991, she underwent VVI PM implantation for atrioventricular II degree Mobitz 1 block, and a unipolar lead was introduced via the left jugular vein. The procedure was performed in our Electrophysiology Lab with a cardiac surgeon on standby, using an excimer laser system emitting the energy at the tip of a flex…

P343 Procalcitonin role in the management of lower respiratory tract infections in preschool children

2017

Introduction One of the major advantage of procalcitonin compared to other parameters is its highly and early increase in response to bacterial infection. The increased procalcitonin levels can be observed 3 to 6 hours after infectious challenge. It is a parameter that made a significant contribution to the clinical diagnosis, severity of infection and in the same time procalcitonin kinetics cand be used to assess the effectiveness of treatment. Methods A single- centre observational study consecutively enrolled 70 preschool children with lower respiratory tract infections who were hospitalised in Paediatric Clinic Hospital of Sibiu between January 2013 and January 2017. Procalcitonin, were…

Atherosclerosis, inflammation and Chlamydia pneumoniae

2009

Coronary heart disease is the single most common cause of illness and death in the developed world. Coronary atherosclerosis is by far the most frequent cause of ischemic heart disease, and plaque disruption with superimposed thrombosis is the main cause of the acute coronary syndromes of unstable angina, myocardial infarction, and sudden death. Atherosclerosis is the result of a complex interaction between blood elements, disturbed flow, and vessel wall abnormality, involving several pathological processes: inflammation, with increased endothelial permeability, endothelial activation, and monocyte recruitment; growth, with smooth muscle cell proliferation, migration, and matrix synthesis; …

Epidemiology of pneumococcal disease in children in Germany

2001

UNLABELLED Recently published and as yet unpublished data allow a reasonable estimate of the annual burden of pneumococcal disease in Germany. At least 277,000 episodes of otitis media and at least 2,000 episodes of sinusitis occur in children under the age of 5 y. Pneumococcal meningitis was found in 200 children under the age of 16 y; the estimate for all age groups ranges from 450 to 1100 cases. Of approximately 150,000 cases of ambulatory pneumococcal pneumonia, at least 63,000-105,000 patients are hospitalized each year. CONCLUSION Further studies of pneumococcal epidemiology in Germany are needed, and continued surveillance will be necessary for a better understanding of the overall b…

The paradox of the evidence about invasive fungal infections prevention

2016

Invasive fungal infections (IFIs) are characterized by high morbidity and mortality in non-neutropenic critically ill patients. Attributable mortality due to Candida spp. infections ranges from about 42 to 63 % [1, 2]. Data from large observational and retrospective studies show an association between early antifungal treatment and improved survival [3, 4]. Updated clinical practice guidelines for the management of candidiasis have been recently published [5]. In 2006, Playford et al. published a Cochrane systematic review investigating the use of antifungal agents for prevention of IFIs in non-neutropenic critically ill patients [6]. In that review, the outcome of proven IFI was defined as…

How to manage aspergillosis in non-neutropenic intensive care unit patients.

2014

Invasive aspergillosis has been mainly reported among immunocompromised patients during prolonged periods of neutropenia. Recently, however, non-neutropenic patients in the ICU population have shown an increasing risk profile for aspergillosis. Associations with chronic obstructive pulmonary disease and corticosteroid therapy have been frequently documented in this cohort. Difficulties in achieving a timely diagnosis of aspergillosis in non-neutropenic patients is related to the non-specificity of symptoms and to lower yields with microbiological tests compared to neutropenic patients. Since high mortality rates are typical of invasive aspergillosis in critically ill patients, a high level …

Best practices, challenges and innovations in pediatrics in 2019

2020

AbstractThis paper runs through key progresses in epidemiology, pathomechanisms and therapy of various diseases in children that were issued in the Italian Journal of Pediatrics at the end of last year. Novel research and documents that explore areas such as allergy, critical care, endocrinology, gastroenterology, infectious diseases, neonatology, neurology, nutrition, and respiratory tract illnesses in children have been reported. These observations will help to control childhood illnesses.

Endemic Treponemal Infections in International Adoptees and Immigrant Children: How Common are they?

2011

VIH et noma au Burkina Faso

2012

Summary Introduction Noma is a “gangrenous” disease beginning in gums and spreading to other parts of the face. It usually occurs in undernourished children with bad orodental hygiene. Its incidence in adults is increasing. HIV infection is very common in African countries. We had for objective to compare noma characteristics in patients with, or without, HIV. Material and methods This retrospective and descriptive study included patients managed for noma in our unit from January 1988 to December 2007. The clinical, epidemiological, and outcome data of patients treated for noma were compared according to HIV infection status. Results Two hundred and twelve patients were included and 14 (6.6…

Cancer of the Penis

2021

Penile carcinoma is a rare and aggressive disease. Its incidence is related with age over 60 and presence of comorbidities such as HPV infection. The higher incidence rate is reached in developing countries. Penile carcinoma is generally a squamous cell carcinoma and it is frequently foregone by a premalignant lesion. Because of its short time to progression, an early detection is mandatory. Good physical examination is the first step toward a correct diagnosis and staging. CT scan and chest X-ray are useful for nodal stage while US and MRI can provide a preoperative assessment of local invasion. Surgical approach depends on invasion and nodal involvement, varying from a local laser ablatio…