Search results for " Inhibition"
showing 10 items of 435 documents
INHIBITION OF POLYPHENOL OXIDASE FROM EGGPLANT.
2005
Sexual Dysfunctions and Their Association with the Dual Control Model of Sexual Response in Men and Women with High-Functioning Autism
2019
Adults with an Autism Spectrum Disorder (ASD) are characterized by impairments in social interaction and communication, repetitive and stereotyped interests and behaviours as well as hyper- and/or hyposensitivities. These disorder specific symptoms could be associated with the development of sexual disorders. The Dual Control Model of Sexual Response presents one approach that is frequently used to explain the emergence of sexual dysfunctions. The aim of the present study was to assess the extent of symptoms of sexual dysfunctions in men and women with ASD and to evaluate their association with the individual propensity of sexual excitation and inhibition as defined by the Dual Control Mode…
Citronellal and citronellol as growth inhibitors of freshwater cyanobacteria
2014
Cyanobacteria possess a very high tolerance relative to environmental factors, so they can be found in almost every aquatic habitat: oceans, freshwaters, hot springs, soils and bare rocks. Nowadays these microorganisms are thought to cause the formation of intensive blooms which result from water eutrophication. In order to suppress blooms in aquatic ecosystems, it is important to limit the growth of blue-green algae, preferably using environment-friendly procedures. In this article we present how two aliphatic, natural monoterpenes: citronellal and citronellol, influence the growth of cyanobacteria. Three species of freshwater cyanobacteria: Anabaena sp., Nodularia moravica and Chroococcus…
The Application of CRISPR/Cas9 Technology for Cancer Immunotherapy: Current Status and Problems
2022
Cancer is one of the main causes of disease-related deaths in the world. Although cancer treatment strategies have been improved in recent years, the survival time of cancer patients is still far from satisfied. Cancer immunotherapy, such as Oncolytic virotherapy, Immune checkpoints inhibition, Chimeric antigen receptor T (CAR-T) cell therapy, Chimeric antigen receptor natural killer (CAR-NK) cell therapy and macrophages genomic modification, has emerged as an effective therapeutic strategy for different kinds of cancer. However, many patients do not respond to the cancer immunotherapy which warrants further investigation to optimize this strategy. The clustered regularly interspaced short …
Corticospinal and intracortical excitability is modulated in the knee extensors after acute strength training
2022
The corticospinal responses to high-intensity and low-intensity strength-training of the upper limb are modulated in an intensity-dependent manner. Whether an intensity-dependent threshold occurs following acute strength training of the knee extensors (KE) remains unclear. We assessed the corticospinal responses following high-intensity (85% of maximal strength) or low-intensity (30% of maximal strength) KE strength-training with measures taken during an isometric KE task at baseline, post-5, 30 and 60-min. Twenty-eight volunteers (23 ± 3 years) were randomized to high-intensity (n = 11), low-intensity (n = 10) or to a control group (n = 7). Corticospinal responses were evoked with transcra…
Self‐control and health‐related behaviour : The role of implicit self‐control, trait self‐control, and lay beliefs in self‐control
2019
Objectives: We tested unique contribution of trait self‐control, implicit self‐control, and lay beliefs in self‐control beliefs to the prediction of health‐related behaviours. We also tested whether relations between trait self‐control and health‐related behaviour, and between implicit self‐control and health‐related behaviours, were moderated by self‐control beliefs. Design: Cross‐sectional, correlational. Methods: Students (N = 176) completed self‐report measures of trait self‐control, lay beliefs that self‐control is limited or non‐limited, non‐planning, participation in health‐related behaviours (impulsive eating, impulsive drinking, exercise avoidance, watching diet, alcohol consumptio…
Rats with elevated genetic risk for metabolic syndrome exhibit cognitive deficiencies when young
2021
Metabolic syndrome (MetS) is a known risk factor for cognitive decline. Using polygenic rat models selectively bred for high and low intrinsic exercise capacity and simultaneously modelling as low and high innate risk factor for MetS respectively, we have previously shown that adult animals with lower exercise capacity/higher MetS risk perform poorly in tasks requiring flexible cognition. However, it is not known whether these deficits in cognition are present already at young age. Also, it is unclear whether the high risk genome is related also to lower-level cognition, such as sensory gating measured as prepulse inhibition. In this study, young and adult (5-8 weeks and ∼9 months) rats sel…
Activity level in left auditory cortex predicts behavioral performance in inhibition tasks in children
2022
Funding Information: We are grateful to Hanna-Maija Lapinkero, Suvi Karjalainen, Maria Vesterinen & Janne Rajaniemi for help with data collection and to Amit Jaiswal, Erkka Heinilä and Jukka Nenonen for their help with preprocessing and scripting. This work was supported by EU project ChildBrain (Horizon2020 Marie Skłodowska-Curie Action (MSCA) Innovative Training Network (ITN) – European Training Network (ETN), grant agreement no. 641652) and the Academy of Finland grant number 311877. Publisher Copyright: © 2022 Sensory processing during development is important for the emerging cognitive skills underlying goal-directed behavior. Yet, it is not known how auditory processing in children is…
Genotype determining aerobic exercise capacity associates with behavioral plasticity in middle-aged rats
2023
Good aerobic fitness associates positively with cognitive performance and brain health and conversely, low aerobic fitness predisposes to neurodegenerative diseases. To study how genotype together with exercise, started at older age, affects brain and behavior, we utilized rats that differ in inherited aerobic fitness. Rats bred for Low Capacity for Running (LCR) are shown to display less synaptic plasticity and more inflammation in the hippocampus and perform worse than rats bred for a High Capacity for Running (HCR) in tasks requiring flexible cognition. Here we used middle-aged (∼ 16 months) HCR and LCR rats to study how genotype and sex associate with anxiety and neural information filt…
Modelling of the cometabolic decomposition of 4-chlorophenol and phenol by the Stenotrophomonas maltophilia KB2 strain
2017
Zaprezentowano model rozkładu 4-chlorofenolu przez szczep Stenotrophomonas maltophilia KB2 w obecności fenolu jako substratu wzrostowego. Opracowanie tego modelu wymagało wykonania czterech serii badań: biodegradacji różnych dawek czystego fenolu, biodegradacji różnych dawek czystego 4-CP, biodegradacji 4-CP w obecności fenolu przy różnym stosunku stężeń obu substratów oraz biodegradacji 4-CP przez komórkiw fazie spoczynku, indukowane wstępnie fenolem. Szczegółowo omówiono sposoby wyznaczania poszczególnych parametrów równań opisujących szybkość degradacji substratów wzrostowego i niewzrostowego oraz przyrostu biomasy. W oparciu o stworzoną bazę danych obliczono m.in. stałe półnasycenia KSg…