Search results for " Intensive care Unit"

showing 10 items of 139 documents

No-touch methods of terminal cleaning in the intensive care unit: results from the first large randomized trial with patient-centred outcomes

2017

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Cross infectionmedicine.medical_specialtySepsiICU-acquired infections; Multidrug resistant organisms; Sepsis; Terminal cleaningIntensive Care UnitMEDLINEMultidrug resistant organismCritical Care and Intensive Care MedicineArticlelaw.inventionSepsis03 medical and health sciencesICU-acquired infection0302 clinical medicineRandomized controlled triallawSepsismedicineHumans030212 general & internal medicineTerminal cleaningIntensive care medicineCross Infectionbusiness.industryMultidrug resistant organismslcsh:Medical emergencies. Critical care. Intensive care. First aid030208 emergency & critical care medicinelcsh:RC86-88.9medicine.diseaseIntensive care unitTerminal cleaningIntensive Care UnitsEmergency medicineICU-acquired infections; Multidrug resistant organisms; Sepsis; Terminal cleaning; Humans; Cross Infection; Intensive Care Units; Critical Care and Intensive Care MedicinebusinessICU-acquired infectionsPatient centredHumanCritical Care
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Work environment, volume of activity and staffing in neonatal intensive care units in Italy: results of the SONAR-nurse study

2016

Background Neonatal units’ volume of activity, and other quantitative and qualitative variables, such as staffing, workload, work environment, care organization and geographical location, may influence the outcome of high risk newborns. Data about the distribution of these variables and their relationships among Italian neonatal units are lacking. Methods Between March 2010-April 2011, 63 neonatal intensive care units adhering to the Italian Neonatal Network participated in the SONAR Nurse study. Their main features and work environment were investigated by questionnaires compiled by the chief and by physicians and nurses of each unit. Twelve cross-sectional monthly-repeated surveys on diff…

Cross-sectional studyStaffingWorkloadCritical Care NursingPediatrics03 medical and health sciences0302 clinical medicineSettore MED/38 - Pediatria Generale E SpecialisticaNursing030225 pediatricsIntensive careCritical care nursingSurveys and QuestionnairesNeonatalIntensive Care Units NeonatalMedicineHumansSurveys and Questionnaire030212 general & internal medicineLocationWorkplaceCross-Sectional Studiebusiness.industryResearchNurse-Patient RelationInfant NewbornPatient AcuityInfantWorkloadPatient AcuityPerinatology and Child HealthNewbornInfant Newborn; Intensive Care Units Neonatal; Nurse-Patient Relations; Patient Acuity; Workload; Cross-Sectional Studies; Humans; Infant Newborn; Intensive Care Units Neonatal; Italy; Surveys and Questionnaires; Critical Care Nursing; Pediatric Nursing; Workload; WorkplacePediatric NursingInfant Newborn; Intensive Care Units Neonatal; Nurse-Patient Relations; Patient Acuity; WorkloadIntensive Care UnitsCross-Sectional StudiesItalyWorkforceInfant; Intensive care units; Neonatal; Newborn; Nurse-patient relations; Patient acuity; Workload; Cross-Sectional Studies; Humans; Infant Newborn; Intensive Care Units Neonatal; Italy; Surveys and Questionnaires; Critical Care Nursing; Pediatric Nursing; Workload; Workplace; Pediatrics Perinatology and Child HealthPediatric nursingbusinessNurse-Patient RelationsHuman
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A novel VIM‐type metallo‐beta‐lactamase (VIM‐14) in a Pseudomonas aeruginosa clinical isolate from a neonatal intensive care unit

2011

AbstractA Pseudomonas aeruginosa highly resistant to carbapenems was isolated in a neonatal intensive care unit in Palermo, Italy. The strain was found to carry a novel VIM‐type enzyme, classified as VIM‐14. The novel enzyme differs from VIM‐4 in a G31S mutation. VIM‐14 was harboured in a class 1 integron with a new organization. The integron carried the genes aac7, blaVIM‐14, blaOXA‐20 and aac4 in that order.

DNA BacterialMicrobiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaNeonatal intensive care unitSettore MED/17 - Malattie Infettivemetallo-b-lactamaseAntibiotic resistancemetallo-β-lactamasemedicine.medical_treatmentMolecular Sequence DataMicrobial Sensitivity TestsBiologySettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeIntegronbeta-LactamasesIntegronscarbapenemlaw.inventionMicrobiologyAntibiotic resistancelawDrug Resistance Multiple BacterialIntensive Care Units Neonatalpolycyclic compoundsmedicineHumansVIM-14Antibacterial agentBase SequencePseudomonas aeruginosaInfant Newbornmetallo‐β‐lactamaseAntibiotic resistance; carbapenems; metallo-b-lactamase; Pseudomonas aeruginosa; VIM-14Sequence Analysis DNAGeneral Medicinebiochemical phenomena metabolism and nutritionbacterial infections and mycosesbiology.organism_classificationIntensive care unitInfectious DiseasesPseudomonas aeruginosaBeta-lactamasebiology.proteinbacteriacarbapenemsVIM‐14PseudomonadaceaeClinical Microbiology and Infection
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Antimicrobial Lessons From a Large Observational Cohort on Intra-abdominal Infections in Intensive Care Units

2021

Severe intra-abdominal infection commonly requires intensive care. Mortality is high and is mainly determined by disease-specific characteristics, i.e. setting of infection onset, anatomical barrier disruption, and severity of disease expression. Recent observations revealed that antimicrobial resistance appears equally common in community-acquired and late-onset hospital-acquired infection. This challenges basic principles in anti-infective therapy guidelines, including the paradigm that pathogens involved in community-acquired infection are covered by standard empiric antimicrobial regimens, and second, the concept of nosocomial acquisition as the main driver for resistance involvement. I…

Drug Resistancemedicine.disease_causeSeverity of Illness Indexlaw.invention0302 clinical medicineENTEROBACTERIACEAElawDrug Resistance Multiple BacterialMedicine and Health SciencesPharmacology (medical)Cross InfectionbiologyBacterialAntimicrobialIntensive care unitAnti-Bacterial AgentsCommunity-Acquired InfectionsEuropeIntensive Care UnitsAnti-Bacterial Agents; Community-Acquired Infections; Critical Illness; Cross Infection; Europe; Humans; Intensive Care Units; Intraabdominal Infections; Microbial Sensitivity Tests; Peritonitis; Sepsis; Severity of Illness Index; Drug Resistance Multiple BacterialESCHERICHIA-COLI030220 oncology & carcinogenesisKLEBSIELLA-PNEUMONIAEBLOOD-STREAM INFECTIONSPYELONEPHRITISMultiplemedicine.medical_specialtyCritical IllnessMicrobial Sensitivity TestsPeritonitisEnterococcus faecalisNO03 medical and health sciencesIntra‑abdominal InfectionsAntibiotic resistanceFOODSepsisIntensive careInternal medicinemedicineHumansFLUOROQUINOLONE RESISTANCEPseudomonas aeruginosabusiness.industrySeptic shockMORTALITYbiology.organism_classificationmedicine.diseaseRISK-FACTORSIntraabdominal Infectionsbusiness030217 neurology & neurosurgeryEnterococcus faecium
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Determinants of COVID-19 Vaccine Rollouts and Their Effects on Health Outcomes

2022

Background Vaccination against the coronavirus disease (SARS-CoV-2) is understood to be the key way out of the COVID-19 pandemic. Limited evidence exists on the determinants of vaccine rollouts and their health effects at the country level. Objective Examine the determinants of COVID-19 vaccine rollouts and their effects on health outcomes. Methods Ordinary least squares regressions with standard errors clustered at the country level for Cross-section and Panel daily data of vaccinations and various health outcomes (new COVID-19 cases, fatalities, intensive care unit (ICU) admissions) for an unbalanced sample of about 200 countries during the period 16 December 2020 to 20 June 2021. Results…

Economics and Econometricsand (iii) COVID-19 cases in neighboring countries can lead to an increase in a country's domestic caseload and hamper efforts in taming its own local outbreak. Conclusions: By providing an early broad overview of the quantitative empirical estimates of the determinants of vaccine rollouts and the effects of COVID-19 vaccines our paper can help policymakers make informed decisions about local and global distributions of vaccines as well as related policy tools such as containment measure.Coronavirus disease 2019 (COVID-19)business.industryHealth PolicyNational accountsOutbreakGeneral Medicine(ii) vaccine deployment significantly reduces new COVID-19 infections Intensive Care Unit (ICU) admissions and fatalities and is more effective when coupled with stringent containment measures or when a country is experiencing a large outbreakVaccination against the coronavirus disease (SARS-CoV-2) is understood to be the key way out of the COVID-19 pandemic. Limited evidence exists on the determinants of vaccine rollouts and their health effects at the country level. Objective: Examine the determinants of COVID-19 vaccine rollouts and their effects on health outcomes. Methods: Ordinary least squares regressions with standard errors clustered at the country level for Cross-section and Panel daily data of vaccinations and various health outcomes (new COVID-19 cases fatalities intensive care unit (ICU) admissions) for an unbalanced sample of about 200 countries during the period 16 December 2020 to 20 June 2021. Results: We find evidence that: (i) early vaccine procurement domestic production of vaccines the severity of the pandemic a country's health infrastructure and vaccine acceptance are significant determinants of the speed of vaccination rolloutHealth outcomesIntensive care unitlaw.inventionVaccinationProcurementlawEnvironmental healthPandemicGeneral Earth and Planetary SciencesMedicinebusinessGeneral Environmental ScienceIMF Working Papers
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Enteral feeding policies for extremely low birth weight infants. A survey in 74 Italian neonatal intensive cAre units

1999

Background: Enterai feeding for infants with birth weight1000 g (ELBWI) is still a controversial issue. The aim of the present survey was to ascertain the attitudes of Italian neonatal intensive care units (NICUs) regarding this point. Method: A questionnaire, with multiple choice answers, regarding the timing of enteral feeding, its progression, the different techniques utilised, the eventual use of fortifiers and the interrupting criteria, was mailed to 92 Italian NICUs. Results: 74 NICUs all over the country participated in the study.1153 ELBWI were hospitalised in 1996 in these Units. Enterai feeding for babies between 501 g and 750 g is started on the 1st day of life in 23.3% of the NI…

Extremely low birthweight infantsEnteral feedingHuman milkNeonatal intensive care units
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An ensemble approach to short-term forecast of COVID-19 intensive care occupancy in Italian Regions

2020

Abstract The availability of intensive care beds during the COVID‐19 epidemic is crucial to guarantee the best possible treatment to severely affected patients. In this work we show a simple strategy for short‐term prediction of COVID‐19 intensive care unit (ICU) beds, that has proved very effective during the Italian outbreak in February to May 2020. Our approach is based on an optimal ensemble of two simple methods: a generalized linear mixed regression model, which pools information over different areas, and an area‐specific nonstationary integer autoregressive methodology. Optimal weights are estimated using a leave‐last‐out rationale. The approach has been set up and validated during t…

FOS: Computer and information sciencesStatistics and ProbabilityTime FactorsOccupancyCoronavirus disease 2019 (COVID-19)Computer science01 natural sciencesGeneralized linear mixed modelSARS‐CoV‐2law.inventionclustered data; COVID-19; generalized linear mixed model; integer autoregressive; integer autoregressive model; panel data; SARS-CoV-2; weighted ensembleMethodology (stat.ME)panel data010104 statistics & probability03 medical and health sciences0302 clinical medicinelawCOVID‐19Intensive careEconometricsHumansclustered data030212 general & internal medicine0101 mathematicsPandemicsStatistics - MethodologySARS-CoV-2Reproducibility of ResultsCOVID-19General Medicineweighted ensembleIntensive care unitResearch PapersTerm (time)integer autoregressiveIntensive Care UnitsAutoregressive modelItalyNonlinear Dynamicsgeneralized linear mixed modelinteger autoregressive modelclustered data; COVID-19; generalized linear mixed model; integer autoregressive; integer autoregressive model; panel data; SARS-CoV-2; weighted ensemble; COVID-19; Humans; Intensive Care Units; Italy; Nonlinear Dynamics; Pandemics; Reproducibility of Results; Time Factors; ForecastingStatistics Probability and UncertaintySettore SECS-S/01Settore SECS-S/01 - StatisticaPanel dataResearch PaperForecasting
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Personal protective equipment and intensive care unit healthcare worker safety in the COVID-19 era (PPE-SAFE): An international survey

2020

Purpose To survey healthcare workers (HCW) on availability and use of personal protective equipment (PPE) caring for COVID-19 patients in the intensive care unit (ICU). Materials and method A web-based survey distributed worldwide in April 2020. Results We received 2711 responses from 1797 (67%) physicians, 744 (27%) nurses, and 170 (6%) Allied HCW. For routine care, most (1557, 58%) reportedly used FFP2/N95 masks, waterproof long sleeve gowns (1623; 67%), and face shields/visors (1574; 62%). Powered Air-Purifying Respirators were used routinely and for intubation only by 184 (7%) and 254 (13%) respondents, respectively. Surgical masks were used for routine care by 289 (15%) and 47 (2%) for…

Face shieldMalebusiness.product_categoryHot TemperatureInfectious Disease TransmissionAllied Health PersonnelNursesCritical Care and Intensive Care MedicineOccupational safety and healthlaw.inventionPatient-to-Professional0302 clinical medicinelawSurveys and QuestionnairesPersonal protective equipmentHealth careMedicine and Health SciencesViralRespiratorRespiratory Protective DevicesHealth care workersHealth services researchHeadacheMasksMiddle AgedIntensive care unitEuropeIntensive Care UnitsFemaleSafetyCoronavirus InfectionsEye Protective DevicesThirstAdultmedicine.medical_specialtyCOVID-19; Health care workers; Intensive care; Personal protective equipment; Safety; Adult; Africa; Allied Health Personnel; Asia; Betacoronavirus; COVID-19; Coronavirus Infections; Europe; Eye Protective Devices; Female; Gloves Protective; Headache; Hot Temperature; Humans; Infectious Disease Transmission Patient-to-Professional; Intensive Care Units; Male; Masks; Middle Aged; North America; Nurses; Oceania; Pandemics; Personal Protective Equipment; Personnel Staffing and Scheduling; Physicians; Pneumonia Viral; Respiratory Protective Devices; SARS-CoV-2; South America; Surgical Attire; Surveys and Questionnaires; Thirst; Health Personnel; Occupational HealthInfectious Disease Transmission Patient-to-ProfessionalAsiaHealth PersonnelPneumonia ViralGlovesOceaniaPersonnel Staffing and SchedulingArticle03 medical and health sciencesBetacoronavirusIntensive carePhysiciansmedicineHumansSurgical AttirePersonal protective equipmentPandemicsOccupational Healthbusiness.industrySARS-CoV-2COVID-19030208 emergency & critical care medicinePneumoniaSouth AmericaProtective030228 respiratory systemCOVID-19Personal protective equipmentSafety Health care workersIntensive careIntensive careEmergency medicineAfricaNorth AmericabusinessGloves ProtectiveJournal of Critical Care
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Prevalence and 30-Day Mortality in Hospitalized Patients With Covid-19 and Prior Lung Diseases.

2021

Patients with pre-existing respiratory diseases in the setting of COVID-19 may have a greater risk of severe complications and even death.A retrospective, multicenter, cohort study with 5847 COVID-19 patients admitted to hospitals. Patients were separated in two groups, with/without previous lung disease. Evaluation of factors associated with survival and secondary composite end-point such as ICU admission and respiratory support, were explored.1,271 patients (22%) had a previous lung disease, mostly COPD. All-cause mortality occurred in 376 patients with lung disease (29.5%) and in 819 patients without (17.9%) (Previous lung disease is a risk factor for mortality in patients with COVID-19.…

HOPE-COVID-19 Health Outcome Predictive Evaluation for COVID-19Respiratory diseasesOriginal30-Day mortalityenfermedades respiratoriasACE2 angiotensin converting enzyme IIlaw.invention0302 clinical medicineCQ/HCQ chloroquine/hydroxychloroquinelawCOPDrespiratory diseasesPrognosisICU intensive care unitIntensive care unitSTROBE strengthening the reporting of observational studies in epidemiologypronósticomedicine.anatomical_structureEPOCCohort studyPulmonary and Respiratory Medicinemedicine.medical_specialty30-day mortalityRT-PCR real time reverse transcriptase-polymerase chain reactionSARS-CoV-2 severe acute respiratory syndrome coronavirus 2WHO World Health OrganizationMERS middle east respiratory syndrome03 medical and health sciencesInternal medicinemedicineCOPDCOVID-19 2019 novel coronavirusRisk factorIQR interquartile rangeLungmortalidad a 30 díasbusiness.industryFEV1 forced expiratory volume in one secondCOVID-19Retrospective cohort studymedicine.diseaseHR hazard ratioICS inhaled corticosteroidsCI confidence intervalCoronavirusCOPD chronic obstructive pulmonary disease030228 respiratory systemRespiratory failureILD interstitial lung diseaseMiddle East respiratory syndromeprognosisHFNC high flow nasal cannulabusiness
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Update I. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19

2020

Purpose To assess efficacy and safety of chloroquine (CQ)/hydroxychloroquine (HCQ) for treatment or prophylaxis of COVID-19 in adult humans. Materials and methods MEDLINE, PubMed, EMBASE and two pre-print repositories (bioRxiv, medRxiv) were searched from inception to 8th June 2020 for RCTs and nonrandomized studies (retrospective and prospective, including single-arm, studies) addressing the use of CQ/HCQ in any dose or combination for COVID-19. Results Thirty-two studies were included (6 RCTs, 26 nonrandomized, 29,192 participants). Two RCTs had high risk, two ‘some concerns’ and two low risk of bias (Rob2). Among nonrandomized studies with comparators, nine had high risk and five moderat…

ICU Intensive care unit;medicine.medical_treatmentCritical Care and Intensive Care MedicineRR Risk Ratio0302 clinical medicineChloroquineRCT Randomized clinical trialMedicineHCQ Hydroxychloroquine;Prospective StudiesProspective cohort studyChloroquine COVID-19 Hydroxychloroquine Mortality SARS-CoV-2ChloroquineECG Electrocardiogram;Rob2 Revised tool for Risk of Bias in randomized trials;CI Confidence interval;Coronavirus InfectionsPost-Exposure ProphylaxisHydroxychloroquinemedicine.drugmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Pneumonia ViralMEDLINEContext (language use)Antiviral AgentsArticleWHO World Health OrganizationBetacoronavirus03 medical and health sciencesInternal medicineHumansMortalityCOVID-19 Coronavirus disease 2019;Post-exposure prophylaxisPandemicsRetrospective StudiesCQ Chloroquine;SARS-CoV-2ROBINS-I Risk of Bias in Non-randomized Studies of Interventions;business.industryCOVID-19030208 emergency & critical care medicineHydroxychloroquineRetrospective cohort studyHCWs Healthcare workers;NOS Newcastle Ottawa Scale;COVID-19 Drug Treatment030228 respiratory systembusinessHR Hazard Ratio;Journal of Critical Care
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