Search results for " Interaction"
showing 10 items of 5187 documents
The strong coupling constant: State of the art and the decade ahead
2022
This document provides a comprehensive summary of the state-of-the-art, challenges, and prospects in the experimental and theoretical study of the strong coupling $\alpha_s$. The current status of the seven methods presently used to determine $\alpha_s$ based on: (i) lattice QCD, (ii) hadronic $\tau$ decays, (iii) deep-inelastic scattering and parton distribution functions fits, (iv) electroweak boson decays, hadronic final-states in (v) e+e-, (vi) e-p, and (vii) p-p collisions, and (viii) quarkonia decays and masses, are reviewed. Novel $\alpha_s$ determinations are discussed, as well as the averaging method used to obtain the PDG world-average value at the reference Z boson mass scale, $\…
$\Lambda_c^{\pm}$ production in pp collisions with a new fragmentation function
2020
Physical review / D D 101(11), 114021 (2020). doi:10.1103/PhysRevD.101.114021
Design, Synthesis, Chemical and Biochemical Insights Into Novel Hybrid Spirooxindole-Based p53-MDM2 Inhibitors With Potential Bcl2 Signaling Attenuat…
2021
The tumor resistance to p53 activators posed a clinical challenge. Combination studies disclosed that concomitant administration of Bcl2 inhibitors can sensitize the tumor cells and induce apoptosis. In this study, we utilized a rapid synthetic route to synthesize two novel hybrid spirooxindole-based p53-MDM2 inhibitors endowed with Bcl2 signaling attenuation. The adducts mimic the thematic features of the chemically stable potent spiro [3H-indole-3,2′-pyrrolidin]-2(1H)-ones p53-MDM2 inhibitors, while installing a pyrrole ring via a carbonyl spacer inspired by the natural marine or synthetic products that efficiently inhibit Bcl2 family functions. A chemical insight into the two synthesized…
Emotions and Activity Recognition System Using Wearable Device Sensors
2021
Nowadays machines have become extremely smart, there are a lot of existing services that seemed to be unexpectable and futuristic decades or even a few years ago. However, artificial intelligence is still far from human intelligence, machines do not have feelings, consciousness, and intuition. How can we help machines to learn about human feelings and understand their needs better? People take their devices wherever they go, what can devices tell us about their owners? Personal preferences and needs are dependent on emotional and situational contexts. Therefore, emotional and activity aware gadgets would be more intuitive and provide more appropriate information to users. Contemporary weara…
Ohjausvuorovaikutuksen laatu ja esiopettajien työhyvinvointi: kontekstitekijöiden ja työstä palautumisen merkitys
2022
Tämän tutkimuksen tavoitteena oli selvittää, missä määrin ohjausvuorovaikutuksen laatu ja esiopettajien työhyvinvointi (koettu stressi ja työstä palautuminen) vaihtelevat suhteessa esiopetuksen kontekstitekijöihin eli esiopetuksen toteutuspaikkaan (päiväkoti tai koulu), ryhmäkokoon ja esiopettajan työkokemukseen. Lisäksi selvitettiin, muuntaako esiopettajien työstä palautuminen ohjausvuorovaikutuksen laadun ja koetun stressin välisiä yhteyksiä esiopetusvuoden aikana. Tutkimukseen osallistui 47 esiopettajaa esiopetusvuoden syksyllä ja keväällä. Ohjausvuorovaikutuksen laatua arvioitiin CLASS Pre-K –havainnointityökalun avulla kolmella osa-alueella: tunnetuki, toiminnan organisointi ja ohjauks…
Added-Mass Based Efficient Fluid–Structure Interaction Model for Dynamics of Axially Moving Panels with Thermal Expansion
2020
The paper considers the analysis of a traveling panel, submerged in axially flowing fluid. In order to accurately model the dynamics and stability of a lightweight moving material, the interaction between the material and the surrounding air must be taken into account. The lightweight material leads to the inertial contribution of the surrounding air to the acceleration of the panel becoming significant. This formulation is novel and the case complements our previous studies on the field. The approach described in this paper allows for an efficient semi-analytical solution, where the reaction pressure of the fluid flow is analytically represented by an added-mass model in terms of the panel…
Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella
2017
The α-proteobacterial genus Bartonella comprises a group of ubiquitous mammalian pathogens that are studied as a model for the evolution of bacterial pathogenesis. Vast abundance of two particular phylogenetic lineages of Bartonella had been linked to enhanced host adaptability enabled by lineage-specific acquisition of a VirB/D4 type IV secretion system (T4SS) and parallel evolution of complex effector repertoires. However, the limited availability of genome sequences from one of those lineages as well as other, remote branches of Bartonella has so far hampered comprehensive understanding of how the VirB/D4 T4SS and its effectors called Beps have shaped Bartonella evolution. Here, we repor…
Stepmothers in narratives : negotiations on relatedness
2018
This study contributes to the existing stepmother research by focusing on interaction as an aspect of stepmother identity construction. Accordingly, identity is seen as negotiated through interaction with other family members. A narrative approach applied to 58 stories written by Finnish stepmothers yielded three identity types: identity restricted by a biological mother, stepmother-centred identity, and team parenthood identity. The most dominant feature, common to all the stories, was that stepmothers perceived themselves primarily in relation to the children’s biological mothers, a stance that often led them to feel threatened. Stepmother identity construction appeared to be problematic …
Predictions of exclusive $\Upsilon$ photoproduction at the LHC and future colliders
2022
The cross section for exclusive $\Upsilon$ ultraperipheral photoproduction at present and future colliders is determined using the low $x$ gluon PDF extracted from an analysis of exclusive $J/\psi$ measurements performed at HERA and the LHC. Predictions are given at next-to-leading order in collinear factorisation over a wide $\gamma p$ centre-of-mass energy range, calculated assuming the non-relativistic approximation for the $\Upsilon$ wave function, and with skewing corrections incorporated.
Open-source QCD analysis of nuclear parton distribution functions at NLO and NNLO
2019
We present new sets of nuclear parton distribution functions (nPDFs) at next-to-leading order (NLO) and next-to-next-to-leading order (NNLO). Our analyses are based on deeply inelastic scattering data with charged-lepton and neutrino beams on nuclear targets. In addition, a set of proton baseline PDFs is fitted within the same framework with the same theoretical assumptions. The results of this global QCD analysis are compared to existing nPDF sets and to the fitted cross sections. Also, the uncertainties resulting from the limited constraining power of the included experimental data are presented. The published work is based on an open-source tool, xFitter, which has been modified to be ap…