Search results for " Invasive"

showing 10 items of 711 documents

Myc Promoter-Binding Protein-1 (MBP-1) Is a Novel Potential Prognostic Marker in Invasive Ductal Breast Carcinoma

2010

BackgroundAlpha-enolase is a glycolytic enzyme that catalyses the formation of phosphoenolpyruvate in the cell cytoplasm. α-Enolase and the predominantly nuclear Myc promoter-binding protein-1 (MBP-1) originate from a single gene through the alternative use of translational starting sites. MBP-1 binds to the P2 c-myc promoter and competes with TATA-box binding protein (TBP) to suppress gene transcription. Although several studies have shown an antiproliferative effect of MBP-1 overexpression on several human cancer cells, to date detailed observations of α-enolase and MBP-1 relative expression in primary tumors versus normal tissues and their correlation with clinicopathological features ha…

CytoplasmAlpha-enolasePROGRESSIONAged 80 and overRegulation of gene expressionMultidisciplinaryQRGenetics and Genomics/Gene ExpressionMiddle AgedPrognosisPathology/Molecular PathologyNUDE-MICETransport proteinCarcinoma DuctalDNA-Binding ProteinsGene Expression Regulation NeoplasticProtein Transportmedicine.anatomical_structureGLYCOLYTIC ENZYMEOncology/Breast CancerMedicineCELL LUNG-CANCER; ALPHA-ENOLASE; PROTEOMIC ANALYSIS; GLYCOLYTIC ENZYME; NUDE-MICE; GENE; IDENTIFICATION; PROGRESSION; EXPRESSION; METASTASESFemalePROTEOMIC ANALYSISEnolase MBP-1 Breast cancer ImmunohistochemistryResearch ArticleAdultEXPRESSIONScienceCELL LUNG-CANCERBreast NeoplasmsBiologyDNA-binding proteinBiomarkers TumormedicineHumansNeoplasm InvasivenessGeneAgedCell NucleusIDENTIFICATIONBinding proteinALPHA-ENOLASEGENEMolecular biologySettore BIO/18 - GeneticaCell nucleusMETASTASESCytoplasmPhosphopyruvate Hydratasebiology.proteinPLoS ONE
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The short-term efficacy and safety of artificial total disc replacement for selected patients with lumbar degenerative disc disease compared with ant…

2018

PurposeTo systematically compare the efficacy and safety of lumbar total disc replacement (TDR) with the efficacy and safety of anterior lumbar interbody fusion (ALIF) for the treatment of lumbar degenerative disc disease (LDDD).MethodsThe electronic databases PubMed, Web of Science and the Cochrane Library were searched for the period from the establishment of the databases to March 2018. The peer-reviewed articles that investigate the safety and efficacy of TDR and ALIF were retrieved under the given search terms. Quality assessment must be done independently by two authors according to each item of criterion. The statistical analyses were performed using RevMan (version 5.3) and Stata (v…

Databases FactualIntervertebral Disc DegenerationCochrane Librarylaw.inventionDatabase and Informatics MethodsMathematical and Statistical Techniques0302 clinical medicineRandomized controlled triallawMedicine and Health SciencesRange of Motion ArticularDatabase Searching030222 orthopedicsMultidisciplinaryQStatisticsRMetaanalysisResearch AssessmentHospitalsTreatment OutcomeResearch DesignMeta-analysisPhysical SciencesObservational StudiesMedicineRange of motionResearch ArticleTotal Disc Replacementmedicine.medical_specialtySystematic ReviewsClinical Research DesignScienceSurgical and Invasive Medical ProceduresResearch and Analysis MethodsDegenerative disc disease03 medical and health sciencesLumbarmedicineHumansStatistical Methodsbusiness.industryEvidence-based medicinemedicine.diseaseSurgeryHealth CareSpinal FusionHealth Care FacilitiesObservational studyAdverse EventsbusinessPublication BiasMathematics030217 neurology & neurosurgeryPLOS ONE
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Risk factors for residual disease at re-TUR in a large cohort of T1G3 patients

2021

Item does not contain fulltext Introduction and objectives: The goals of transurethral resection of a bladder tumor (TUR) are to completely resect the lesions and to make a correct diagnosis in order to adequately stage the patient. It is well known that the presence of detrusor muscle in the specimen is a prerequisite to minimize the risk of under staging. Persistent disease after resection of bladder tumors is not uncommon and is the reason why the European Guidelines recommended a re-TUR for all T1 tumors. It was recently published that when there is muscle in the specimen, re-TUR does not influence progression or cancer specific survival. We present here the patient and tumor factors th…

Detrusor musclemedicine.medical_specialty030232 urology & nephrologyUrologyDiseaseLogistic regression03 medical and health sciencesTumor Status0302 clinical medicineRe-transurethral resection of the bladderRecurrenceRisk FactorsUrological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15]MedicineHumansStage (cooking)Non-muscle invasive bladder cancer; Re-transurethral resection of the bladder; Residual disease; Recurrence; ProgressionNeoplasm StagingRetrospective StudiesUnivariate analysisCarcinoma Transitional CellProgressionbusiness.industryRetrospective cohort studyGeneral MedicineResidual diseaseReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Settore MED/24medicine.anatomical_structureUrinary Bladder NeoplasmsConcomitantNon-muscle invasive bladder cancerbusiness
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Tumors of the central nervous system in children and adolescents.

2011

Multimodal treatment approaches for children with tumors of the central nervous system (CNS) have markedly contributed to improved survival. Before 1970, the survival rate among children with medulloblastoma, the most common malignant CNS tumor in children, was about 20%. At present, in contrast, cure can be achieved in more than 75% of children with a favorable constellation of risk factors. In this review article for clinicians, we give an overview of the current understanding of the pathology, presenting manifestations, early diagnosis, and treatment of CNS tumors in children and adolescents.We report the research findings of the German Treatment Network "HIT" and selectively review the …

Diagnostic ImagingMalePediatricsmedicine.medical_specialtyAdolescentIntracranial PressureQuality Assurance Health CareCentral nervous systemImproved survivalReview ArticleCentral Nervous System NeoplasmsGermanymedicineMultimodal treatmentHumansNeoplasm InvasivenessCNS TUMORSChildSurvival rateNeoplasm StagingMedulloblastomabusiness.industryInfantGeneral Medicinemedicine.diseasePrognosisCombined Modality TherapyReview articlemedicine.anatomical_structureTreatment OutcomeChild PreschoolImmunologyFemaleNeoplasm GradingMalignant CNS TumorbusinessFollow-Up StudiesDeutsches Arzteblatt international
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Fractal-structured multifocal intraocular lens

2017

[EN] In this work, we present a new concept of IOL design inspired by the demonstrated properties of reduced chromatic aberration and extended depth of focus of Fractal zone plates. A detailed description of a proof of concept IOL is provided. The result was numerically characterized, and fabricated by lathe turning. The prototype was tested in vitro using dedicated optical system and software. The theoretical Point Spread Function along the optical axis, computed for several wavelengths, showed that for each wavelength, the IOL produces two main foci surrounded by numerous secondary foci that partially overlap each other for different wavelengths. The result is that both, the near focus an…

DiffractionOptical PhenomenaFocus (geometry)VisionSocial Scienceslcsh:MedicinePhysics::Optics01 natural sciences0302 clinical medicineMedicine and Health SciencesPsychologylcsh:ScienceLens (Anatomy)PhysicsMultidisciplinaryPhysicsOphthalmic ProceduresCataract SurgeryOptical LensesWavelengthFractalsOptical EquipmentPhysical SciencesEngineering and TechnologySensory PerceptionAnatomyDiffractionResearch ArticlePoint spread functionOcular AnatomyGeometryEquipmentSurgical and Invasive Medical ProceduresIn Vitro TechniquesProsthesis DesignProof of Concept Study010309 optics03 medical and health sciencesFractalOpticsOcular SystemOptical transfer function0103 physical sciencesChromatic aberrationPrototypesComputer Simulationbusiness.industrylcsh:RBiology and Life SciencesModels TheoreticalMultifocal Intraocular LensesOptical axisTechnology DevelopmentFISICA APLICADAWaves030221 ophthalmology & optometryEyeslcsh:QbusinessHeadMathematicsNeuroscience
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Extension d'Ambrosia artemisiifolia L. dans le département de la Côte d'Or

2006

International audience

ENVAHISSANTE[SDV] Life Sciences [q-bio][SDE] Environmental SciencesAMBROISIEASTERACEAE[SDV]Life Sciences [q-bio][SDE]Environmental SciencesPLANTE INVASIVEAMBROSIA ARTEMISIIFOLIA L.ComputingMilieux_MISCELLANEOUS
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Intrinsic competition between two European egg parasitoids of the brown marmorated stink bug

2020

Following the accidental introduction and spread of the invasive polyphagous agricultural pest Halyomorpha halys (Stål) (Hemiptera: Pentatomidae), the two European egg parasitoids Anastatus bifasciatus (Geoffroy) (Hymenoptera: Eupelmidae) and Ooencyrtus telenomicida (Vassiliev) (Hymenoptera: Encyrtidae) have been investigated for inundative biological control. Since the competititve outcome between the two generalist parasitoids is difficult to predict, intrinsic competition was investigated with a time-course development study. Both species readily oviposited in H. halys eggs containing eggs and early instar larvae of the competitor, but oviposition decreased when eggs contained late insta…

EcologyOoencyrtus telenomicidamedia_common.quotation_subjectBiological pest controlBiologybiology.organism_classificationInvasive speciesCompetition (biology)Anastatus bifasciatus biological control Halyomorpha halys invasive species multiparasitism Ooencyrtus telenomicidaSettore AGR/11 - Entomologia Generale E ApplicataInsect ScienceBrown marmorated stink bugAgronomy and Crop Sciencemedia_commonJournal of Applied Entomology
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The invasion history of Elodea canadensis and E. nuttallii (Hydrocharitaceae) in Italy from herbarium accessions, field records and historical litera…

2022

AbstractWe analysed the invasion history of two North American macrophytes (Elodea canadensis and E. nuttallii) in Italy, through an accurate census of all available herbarium and field records, dating between 1850 and 2019, and a rich literature collection describing the initial introduction and naturalisation phase that supports the results obtained by the occurrence records. Elodea canadensis arrived in Italy before 1866 and had two invasion phases, between the 1890s and 1920s and between the 1990s and 2000s; E. nuttallii, probably arrived in the 1970s, started invading in 2000 and the invasion is still ongoing. Botanical gardens and fish farming played a crucial role in dispersal and na…

EcologySettore BIO/02 - Botanica SistematicaHerbarium sampleInvasive specieaquatic alien speciesfloristic recordsherbarium samplesHistorical recordinvasive speciesMacrophytesAquatic alien species Invasive species Freshwater Herbarium samples Floristic records Historical records MacrophytesFreshwateraquatic alien species; invasive species; freshwater; herbarium samples; floristic records; historical records; macrophyteshistorical recordsFloristic recordEcology Evolution Behavior and SystematicsSettore BIO/03 - Botanica Ambientale e ApplicataAquatic alien specie
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New Data on Native and Alien Vascular Flora of Sicily (Italy): New Findings and Updates

2023

In this paper, based on fieldwork and herbaria surveys, new data concerning the presence of 32 native and alien vascular species for Sicily (Italy) are provided. Among the native species, the occurrence of the following taxa is reported for the first time or confirmed after many decades of non-observation: Aira multiculmis, Arum maculatum, Carex flacca subsp. flacca, Mentha longifolia, Oxybasis chenopodioides, Najas minor and Xiphion junceum. Furthermore, we document the presence of three native species (Cornus mas, Juncus foliosus and Limonium avei) that, despite being repeatedly observed in Sicily and reported in the literature, are inexplicably omitted by the most recent authoritative ch…

Ecologyfloristic recordbiological invasionsbiodiversity recordfloristic recordsbiological invasionPlant Sciencemediterranean floraregional florainvasive plantmediterranean flora; biodiversity records; distribution range; exotic species; floristic records; invasive plants; regional flora; species occurrence; biological invasions; alien species managementexotic speciebiodiversity recordsinvasive plantsdistribution rangespecies occurrenceexotic speciesalien species managementEcology Evolution Behavior and Systematics
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Aortic valve stenosis: Treatments options in elderly high-risk patients

2016

Not available

Elderly patientsTranscatheter aortic valve implantationMinimaly invasive surgerySymposium: Transcatheter aortic valve implantationAortic valve stenosiAortic valve stenosis; Elderly patients; Minimaly invasive surgery; Risck stratification; Transcatheter aortic valve implantation; Cardiology and Cardiovascular Medicine; Geriatrics and GerontologyAortic valve stenosisGeriatrics and GerontologyRisck stratificationCardiology and Cardiovascular MedicineElderly patient
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