Search results for " Ip"
showing 10 items of 320 documents
La casa ipertestuale. Le stanze e lo spazio-soglia
2008
Il saggio descrive i risultati di un'esperienza di seminario/workshop extracurriculare, svoltosi a Palermo nel 2005 (dal titolo: “Futura. Come abiteremo domani”). La metafora dell’ipertesto, spesso utilizzata da architetti, filosofi e urbanisti come metafora significativa per descrivere la condizione metropolitana contemporanea, risulta particolarmente efficace quale rappresentazione sintetica dell’idea di casa che abbiamo inteso indagare, per alcune sue qualità essenziali che trovano immediato riscontro nelle nuove modalità dell’abitare. All’interno del tema più generale della casa “ipertestuale”, la sperimentazione diretta dal Emanuele Palazzotto ha inteso esplorare alcune possibilità di …
L'aborto ricorrente spontaneo
2004
Numerose ipotesi etiopatogenetiche sono state fatte riguardo l'abortività ricorrente e svariate terapie sono state adottate nel tempo.Oggi le nuove prospettive riguardano la correlazione ARS e trombofilia.
Proxy Mobile IPv6-Based Seamless Handover
2013
A prospective next generation wireless network is expected to integrate harmoniously into an IP-based core network. It is widely anticipated that IP-layer handover is a feasible solution to global mobility. However, the performance of IP-layer handover based on basic Mobile IP (MIP) cannot support real time services very well due to long handover delay. The Internet Engineering Task Force (IETF) Network-based Localized Mobility Management (NETLMM) working group developed a network-based localized mobility management protocol called Proxy Mobile IPv6 (PMIPv6) to reduce the handoff latency of MIPv6. Moreover, PMIPv6 provides the IP with the mobility to support User Equipments (UEs) without it…
Obesità viscerale, rischio cardiometabolico e ipertrofia ventricolare sinistra: ruolo dell'adiponectina plasmatica
Lo studio è stato disegnato allo scopo di valutare la prevalenza delle comorbilità cardio-metaboliche e le modificazioni morfologiche della struttura del ventricolo sinistro in una coorte di pazienti suddivisi sulla scorta dei valori normali o ridotti di adiponectina.L'obiettivo principale dello studio è stato quello di analizzare se la riduzione dell'adiponectina plasmatica possa essere considerata un marker di rischio cardiometabolico.
Lipase elevation and type 1 diabetes mellitus related to immune checkpoint inhibitor therapy – A multicentre study of 90 patients from the German Der…
2021
Abstract Aim Immune checkpoint inhibition (ICI) triggers immune-related adverse events (irAEs). The relevance of lipase elevation remains unclear. Patients and methods Skin cancer patients with newly detected serum lipase elevation (at least twofold upper normal limit) or newly diagnosed type I diabetes mellitus upon ICI therapy were retrospectively collected at 14 German skin cancer centres. Results We identified 68 patients with lipase elevation occurring after a median time of 19 (range 1–181) weeks on ICI, 15 (22%) thereof had symptoms consistent with pancreatitis. Forty-seven patients (73%) had other irAE, mainly colitis. Discontinuation (n = 24, 35%) or interruption (n = 26, 38%) of I…
Relationships between metabolic syndrome and left ventricular mass in hypertensive patients. Does sex matter ?
2008
Several studies documented an association between metabolic syndrome (MetS) and left ventricular (LV) hypertrophy. However, only in a few of these studies the impact of MetS on left ventricular mass (LVM) was separately analysed by gender, with conflicting results. The aim of our study was to verify, in a wide sample of essential hypertensive patients, the influence of gender, if any, on the relationship between MetS and LVM. We enrolled 475 non-diabetic subjects (mean age: 46 +/- 11 years), with mild-to-moderate essential hypertension, of whom 40% had MetS, defined on the basis of Adult Treatment Panel III (ATPIII) criteria. All the patients underwent a 24-h ambulatory blood pressure monit…
Plasma Aldosterone and Its Relationships With Left Ventricular Mass in Essential Hypertensive Patients With the Metabolic Syndrome
2008
BACKGROUND: The association of aldosterone with the metabolic syndrome (MetS) has not been fully elucidated. The aim of our study was to evaluate the relationships of plasma aldosterone concentration (PAC) with MetS and left ventricular mass (LVM) in nondiabetic Caucasian patients with essential hypertension. METHODS: Measurements were taken with the patients off antihypertensive medications. The measurements included 24-h blood pressure (BP) readings, plasma renin activity (PRA) and aldosterone, and an echocardiogram. RESULTS: Subjects with MetS (n = 201) had higher age-adjusted PAC (10.2 +/- 5.8 vs. 11.6 +/- 5.9 ng/dl; P = 0.01) and greater age-adjusted LVM indexed for height2.7 (LVMH2.7)…
Effects of hypocaloric very-low-carbohydrate diet vs. Mediterranean diet on endothelial function in obese women
2009
Obesity is a cardiovascular risk factor associated with endothelial dysfunction, but the effect of different weight loss strategies on endothelial function is not known. The effect of diet on endothelial function in two hypocaloric diets, a very-low-carbohydrate diet (A) and a Mediterranean diet (M), was measured by brachial artery flow-mediated dilation (FMD). Design Using a longitudinal, randomized, open study design, subjects were engaged in a 2-month weight loss diet. FMD, inflammatory cytokines [interleukin-6 (IL-6) and tumour necrosis factor-alpha] and a marker of oxidative stress [8-iso-prostaglandin F2alpha (8-iso-PGF2alpha)] were measured in subjects on three occasions: before init…
Dall’iperestetica all’anestetica: la negazione dell’umano nella società dell’apparenza
2021
Viviamo nella “società dell’immagine” che ottunde la sensibilità e produce indifferenza. Il saggio mette a fuoco la ricerca ossessiva di una bellezza superficiale e apparente in ogni ambito della vita quotidiana e la conseguente perdita dei valori morali. Per contrastare questa anestetizzazione dovuta all’esasperata tendenza all’eccesso e al superamento dei limiti del giusto, del necessario, del conveniente e del bello, il saggio propone di recuperare l’antica dimensione etico-estetica del bello in linea con alcuni interessi dell’Everyday Aesthetics. We live in the "society of the image" that obtunds sensitivity and produces indifference. The essay focuses on the obsessive search for a shal…
BAG3 and friends: co-chaperones in selective autophagy during aging and disease.
2011
There is a reciprocal change in the expression of two members of the BAG (Bcl-2-associated athanogen) family, BAG1 and BAG3, during cellular aging and under acute stress ("BAG1-BAG3-switch"). BAG3 was recently described as a mediator of a novel macroautophagy pathway that uses the specificity of heat shock protein 70 (HSP70) to misfolded proteins and also involves other protein partners, such as HSPB8. Also crucial for induction and execution of autophagy are sequestosome-1/p62 (SQSTM1/p62) and LC3, an autophagosome-associated protein. In this novel pathway, BAG3 mediates the targeting and transport of degradation-prone substrates into aggresomes via the microtubule-motor dynein. Interestin…