Search results for " Isomerization"

showing 7 items of 27 documents

Conformational properties of N-acetyl-N-methyl-alpha,beta-dehydroalanine N'-methylamide.

2006

The conformational properties of Ac-Delta(Me)Ala-NHMe (N-acetyl-N-methyl-alpha,beta-dehydroalanine N'-methylamide), as the simplest model of N-methyl-alpha,beta-dehydroamino acids, was examined with theoretical methods and in comparison with Ac-DeltaAla-NHMe and Ac-DeltaAla-NMe(2). The N-terminal amide of the Delta(Me)Ala residue easily adopts the configuration cis and the torsion angles phi, psi are highly flexible. The Delta(Me)Ala residue is a conformational flexibilizer as compared to the parent DeltaAla, which is a conformational stiffener. This seems to be the reason why Delta(Me)Ala is found in small natural cyclic peptides, where it ensures the conformational flexibility necessary f…

chemistry.chemical_classificationModels MolecularAlanineMolecular StructureStereochemistryBiophysicsMolecular ConformationHydrogen BondingMethylamideAmidesGeneral Biochemistry Genetics and Molecular BiologyCis trans isomerizationCyclic peptidechemistry.chemical_compoundResidue (chemistry)chemistryModels ChemicalDehydroalanineAmideTheoretical methodsPeptidesActa biochimica Polonica
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Modified photobehavior of carboxylic acid derivatives induced by protonation

1987

Abstract A series of carboxylic acid derivatives 1–6 containing a second interacting function have been converted into the corresponding O -protonated species or acylium ions upon treatment with 96% sulfuric acid or oleum, respectively, at room temperature. The resulting stable cations have been spectroscopically characterized and submitted to irradiation. Cis-trans photoisomerization was observed in the ionic speciesderived from trans -crotonic, fumaric and maleic acids, and maleic anhydride. By contrast protonated crotonolactone 5a+ was found to be photostable. Finally, protonated α-bromobutyrolactone 6a+ was clean and efficiently dehydrohalogenated to 5a+ upon irradiation. Since the norm…

chemistry.chemical_classificationPhotoisomerizationChemistryCarboxylic acidOrganic ChemistryMaleic anhydrideSulfuric acidProtonationBiochemistryMedicinal chemistryCis trans isomerizationOleumchemistry.chemical_compoundDrug DiscoveryOrganic chemistryAliphatic compoundTetrahedron
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Photoswitchable coordination compounds

2001

Photoswitchable compounds represent an attractive class of materials in coordination chemistry. Recent progress dealing with transition metal compounds involving photo-induced changes of the magnetic and/or optical properties to long-lived metastable states are covered in the present review article. The basic photophysical phenomena together with representative examples such as nitroprusside derivatives, relevant spin crossover complexes, stilbenoid complexes and finally Prussian blue analogues are discussed. Some possible applications regarding energy and information storage are suggested at the end.

chemistry.chemical_classificationPrussian blueChemistryInformation storageNanotechnologyPhotomagnetismLIESSTCoordination complexInorganic Chemistrychemistry.chemical_compoundTransition metalPhoto isomerizationComputational chemistrySpin crossoverMaterials ChemistryPhysical and Theoretical ChemistryCoordination Chemistry Reviews
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Thermal Rearrangements of Perchlorohexatrienes-Structures and Experimental and Theoretical Evaluation of Pathways to Isomerization and Cyclization

2009

We have prepared trans- (1) and cis-octachloro-1,3,5-hexatriene (2) by known routes and studied their thermal behavior experimentally and theoretically by ab initio calculations. The three double bonds in 1 and 2 are completely decoupled due to steric hindrance by the eight Cls, as indicated by calculations as well as the single-crystal X-ray structure of 1. The cis isomer 2 can be isomerized to the trans isomer 1 by heating it to 220–250 °C either neat or dissolved in high-boiling solvents, leading to a roughly 2:1 mixture of trans and cis isomers. Calculations at several different levels of theory predict 1 and 2 to be isoenergetic within 2 kJ mol–1. Unimolecular cis/trans isomerization i…

chemistry.chemical_classificationSteric effectsDouble bondFlash vacuum pyrolysisOrganic ChemistryPhotochemistryCis trans isomerizationchemistry.chemical_compoundchemistryOrganic chemistryCyclopentenePhysical and Theoretical ChemistryIsomerizationCis–trans isomerismFulveneEuropean Journal of Organic Chemistry
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On the role of the triplet state in the cis/trans isomerization of rhodopsin: A CASPT2//CASSCF study of a model chromophore

2011

The possibility of population of the lowest-lying triplet state (T1) in the early events of the photochemical isomerization process of a model chromophore of Rhodopsin (Rh) has been analyzed using multireference perturbation theory (CASPT2//CASSCF) methods. It is shown that the characteristics of the isomerization process namely small S1−T1 gap, presence of hydrogen out of plane active vibrational modes, and existence of a dense manifold of vibrational states, render possible the fulfilment of the conditions needed for the population of T1. The possible consequences for the photochemistry and photophysics of Rh are also discussed. © 2011 Wiley Periodicals, Inc. Int J Quantum Chem 111:3431–3…

education.field_of_studybiologyChemistrytripletPopulationChromophoreCondensed Matter PhysicsPhotochemistryInternal conversion (chemistry)Atomic and Molecular Physics and OpticsCis trans isomerizationIntersystem crossingrhodopsinComputational chemistryRhodopsinPHOTOISOMERIZATIONCASPT2//CASSCFbiology.proteinPhysical and Theoretical ChemistryTriplet stateeducationIsomerization
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The Boulton-Katritzky Reaction: A Kinetic Study of the Effect of 5-Nitrogen Substituents on the Rearrangement of Some (Z)-phenylhydrazones of 3-Benzo…

2014

The kinetics of the ring-into-ring conversion of some new (Z)-phenylhydrazones of 3-benzoyl-1,2,4-oxadiazole containing different nitrogen-substituents at C-5 (3b-d; X = NHMe, NMe2, and NHCOMe) into the relevant triazoles 4b-d have been examined in a wide range of pS+ (0.1-11.9) in 1:1 (v/v) dioxane/water solution. The obtained results have been compared with previous data concerning the (Z)-phenyl-hydrazone of 5-amino-3-benzoyl-1,2,4-oxadiazole (3a; X = NH2). All of the studied (Z)-phenylhydrazones rearrange through three different pathways (specific acid-catalysed, uncatalysed and general base-catalysed). The different effects of the substituents on the course of the rearrangement in the …

hydrazoneKinetics Rearrangement Heterocycles Hydrazones IsomerizationrearrangementkineticSettore CHIM/06 - Chimica OrganicaKinetics / Rearrangement / Heterocycles / Hydrazones / Isomerizationisomerizationheterocycle
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Conformational-Dependent Photodissociation of Glycolic Acid in an Argon Matrix

2023

Ultraviolet-induced photodissociation and photo-isomerization of the three most stable conformers (SSC, GAC, and AAT) of glycolic acid are investigated in a low-temperature solid argon matrix using FTIR spectroscopy and employing laser radiation with wavelengths of 212 nm, 226 nm, and 230 nm. The present work broadens the wavelength range of photochemical studies of glycolic acid, thus extending the understanding of the overall photochemistry of the compound. The proposed kinetic model for the photodissociation of glycolic acid proceeds from the lowest energy conformer (SSC). The model suggests that ultraviolet light induces isomerization only between the SSC and GAC conformers and between …

photochemistrymatrix isolationGeneral Medicinedissociationreaktiomekanismithydroxy acidglycolic acidisomerizationvibrational spectroscopychemical kineticshajoaminen (kemia)reaction mechanismvalokemiaglycolic acid; hydroxy acid; dissociation; isomerization; chemical kinetics; reaction mechanism; matrix isolation; vibrational spectroscopy; photochemistryPhotochem
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