Search results for " Kir"

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

2001

Researchers worldwide with information about the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer were invited to provide that data in a schematized format for inclusion in a collaborative database called RASCAL (The Kirsten ras in-colorectal-cancer collaborative group). Our results from 2721 such patients have been presented previously and for the first time in any common cancer, showed conclusively that different gene mutations have different impacts on outcome, even when the mutations occur at the same site on the genome. To explore the effect of Ki-ras mutations at different stages of colorectal cancer, more patients were recruited to the database, whi…

Eeva-Liisa Mannerin ”Kirjoituskone” : geneettinen, mediateknologinen ja konseptuaalinen näkökulma

2019

Consumer behavior with augmented reality in retail: a review and research agenda

2021

Driven by the rapid technological development and adoption of augmented reality (AR) in retail, academic research has grown rapidly. Our purpose is to understand the reasons why consumers use augmented reality in retail and what outcomes retailers can expect. This study presents a systematic literature review and summarizes the current empirical knowledge on consumer behavior with AR in retail. This topic remains scattered between various literature streams showing that the potential of AR to create value for consumers lays in its ability to generate utilitarian and hedonic value, to improve decision-making, and to enhance personalization of the virtual self. Then, this study warns about ne…

Employee trust repair: A systematic review of 20 years of empirical research and future research directions

2021

Employee trust, and increasingly its absence, is a critical topic for researchers and practitioners interested in social relations in the context of work and organizing. Employee trust repair is particularly important in the current disrupted work environment, due to unpredictable changes such as the Covid-19 pandemic and the uncertainty those bring to our lives. It is not surprising that employee trust is attracting increasing interest among researchers and practitioners alike. In this article, we systematically review and take stock of the research on trust repair conducted in the past two decades to provide comprehensive insights and future research directions for researchers and manager…

Autobiographical reading

2010

In my book, I have attempted the elaboration of a system for rereading 20th-century Hungarian autobiographies, by way of putting the emphasis on theoretical considerations. (From the “Death of the Author” to the Resurrection of the Author, Stereotypes in Autobiographical Reading) The major analytical aspects of the Autobiographical Reading focuses on the language based means of the representation of the Self. (Language and Subject, Staging the Self, Inter-Replacing Play of Image and Representation, Relationship between the Narrating and the Narrated Autobiographical Self, Memory and Identity) The choice of this subject matter is justified first of all by the fact that the conditions for the…

Ajan arvoituksia : fiktiivinen ajan kokemus Cormac McCarthyn romaanissa No country for old men

2013

Tarkastelen pro gradu -tutkielmassani inhimillisen ajan kokemuksen representaatioita Cormac McCarthyn romaanissa No Country for Old Men (2005). Tutkimuksessani selvitän, minkälaisen kuvan teoksen henkilöhahmojen kokemukset antavat ihmisen tavasta kokea aikaa. Lähtökohtanani on Paul Ricœurin ajatus, että fiktio kykenee luomaan ajan kokemuksen variaatioita, joiden avulla lukija voi rikastuttaa omaa ymmärrystään ajallisuudesta. Työn teoriaosuudessa esittelen erilaisia aikakäsityksiä monitieteisestä näkökulmasta. Tärkeimpänä rajanvetona on Ricœuriä seuraten eronteko objektiivisen kosmologisen ajan ja subjektiivisen fenomenologisen ajan välille. Lisäksi tarkastelen kaunokirjallisuuden kykyä ja k…

www.climateofburundi.org

2010

Daily rainfall and air temperature data were collected by IGEBU. For a given station, the number of missing daily rainfall data, MRDm (days), was determined for each month of the recording period. The monthly rainfall depth, Pm (mm), and the monthly number of rainy days, NRDm (days),were determined for each month with a complete record of daily rainfall data. For a given month, Pm was obtained by summing the daily rainfall depth values and NRDm was obtained by counting the number of days of the month characterized by a daily rainfall depth greater than zero. The number of missing daily temperature data, MTDm (days), was also determined for each month of the recording period. The mean of the…

Role of HLA-B α-3 domain amino acid position 194 in HIV disease progression

2013

HLA class I molecules play a role in the regulation of innate immune response. Therefore, the interaction of HLA class I molecules with different activating and inhibitory receptors leads to balancing the immune response. Among the different family of receptors, NK receptors KIR3DL1/S1 and LIR1, play a major role. Aim of this study was to evaluate the role of amino acid polymorphic positions of HLA class I molecules interacting with NK receptors in HIV progression. In order to minimize the influence of viral variability, a cohort of children with a nosocomial monophyletic HIV-1 infection from the Benghazi Children Hospital has been evaluated. To assess the role of single amino acid position…

NELLI vie tiedonlähteille

2006

Ruolo dell'interazione NK/KIR nella storia naturale delle infezioni virali

2017

Immunological mechanisms involved in the genesis of the immune response against viral infections take into account the activation of both innate adaptative response. Innate immune defenses trigger a rapid local response, which is often sufficient to control viral infection, and promotes the subsequent activation of specific immune defenses. Natural killer (NK) cells that constitute a subpopulation of lymphocyte-related cells are a key factor of innate immune response and play a role in defense against viral infections by killing infected cells or by producing cytokines and interacting with adaptative immune system's cells. Killer immunoglobulin-like receptors (KIRs) regulate the activation …