Search results for " LAB"
showing 10 items of 2393 documents
La remuneración por desempeño en el ámbito educativo público
2017
La labor de los maestros de escuela es un trabajo complejo y difícil de evaluar. No obstante, existen varias propuestas para evaluar el trabajo de los maestros y vincular el salario a la calidad de la docencia impartida. En este estudio se analizan las diferentes posibilidades para evaluar la docencia: i) la evaluación de conductas de los maestros (evaluación del desempeño) ii) Retribuir al maestro dependiendo de las notas obtenidas por sus alumnos en exámenes estatales (retribución por cumplimiento de objetivos). Desde esta perspectiva se analiza las ventajas e inconvenientes de los dos sistemas y cómo diseñar un sistema retributivo que distinga los buenos de los malos profesores de forma …
The impact of kaizen events on improving the performance of automotive components first tier suppliers
2009
Purpose of this paper: The aim of this paper is to explore the possibility of improving production indicators by implementing Kaizen Events. The teams are composed of both managers and operators with the aim of developing and/or implementing improvements in a period of from 3 to 5 days. Methodology: The empirical research will consist of the description of the results obtained in 11 industrial companies from the automotive components industry In each of the companies, we have followed up different interventions over a 9-12 month period. Findings: We shall present the initial situation; the activities carried out by the company and the evolution of the manufacturing performance approximately…
Looking for a virtuous pattern of growth. Some insights for discussion
2016
Este artículo busca arrojar un poco más de luz en el actual debate «manufacturas frente a servicios» y su papel en el crecimiento económico, tomando como punto de partida la Comunicación de la CE Por un Renacimiento Industrial Europeo. Se presentan dos criterios para evaluar las razones que justifican el apoyo a determinados sectores económicos (ya sea manufacturas o servicios): 1. la capacidad de generar empleo y 2. la capacidad de presentar un crecimiento positivo de la productividad. El artículo evalúa las manufacturas y los servicios en función de estos dos criterios, utilizando la base de datos PREDICT, caracterizada por su elevada desagregación sectorial. La conclusión a la que se lle…
Remote, web-based laboratory for Programmable Logic Devices
2009
Abstract This work proposes a web-based laboratory for remotely testing FPGA programs on an evaluation board. Using a web browser, the user can download a device configuration file (previously generated with the FPGA commercial tool) and test it in a real FPGA board located in a remote laboratory at the University facilities. The user can control inputs and check outputs’ state. This preliminary study tries to evaluate the possibilities that can be offered to the user, and the restrictions that might apply. Additionally, it describes the proposed infrastructure (hardware and software) needed to successfully deal with all the interesting features that a remote lab system for programmable log…
A new technique for real-time analysis of caspase-3 dependent neuronal cell death
2007
Several markers are available to identify cells undergoing programmed cell death, but so far they are only applicable on fixed material. Therefore, no information on the kinetics of apoptosis can be obtained, although apoptosis is a dynamic cell process. Here, we describe a new technique that allows the real-time observation of the onset of apoptosis in primary neurons. Neurons are transfected with a plasmid that codes for a fluorescent protein localized in the soma. Upon activation of caspase-3, which represents the point-of-no-return in the apoptosis process, the fusion protein is cleaved and as a consequence translocates into the nucleus. The onset of apoptosis is thus visualized by tran…
Apoptosis causes lumen formation during angiogenesis in vitro.
2002
Peroxisome proliferator-activated receptor δ (PPARδ) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis
2005
Activation of peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma plays beneficial roles in cardiovascular disorders such as atherosclerosis and heart reperfusion. Although PPARalpha and gamma have been documented to reduce oxidative stress in the vasculature and the heart, the role of PPARdelta remains poorly studied.We focused on PPARdelta function in the regulation of oxidative stress-induced apoptosis in the rat cardiomyoblast cell line H9c2. Using semi-quantitative reverse transcriptase-polymerase chain reaction (RT-PCR), we showed that PPARdelta is the predominantly expressed isotype whereas PPARalpha was weakly detected. By performing cell viability assays, we …
Fundamentos del régimen jurídico de las invenciones laborales en Cuba. Un estudio comparado con el modelo español
2018
El crecimiento económico se impulsa en gran medida por la innovación que garantiza nuevas oportunidades de producción más eficientes para los agentes innovadores al ver favorecida su capacidad productiva. El efecto de este proceso sobre el crecimiento dependerá, entre otras cuestiones, de la influencia que provoquen las innovaciones, del grado en que estas se difundan hacia el resto de los sectores y de cuán profundas sean las relaciones de complementariedad productiva de los agentes innovadores con el resto del engranaje productivo. De tal forma, en esta correlación, a medida que la innovación se materializa en la expansión o creación de sectores y actividades específicas que incitan la pr…
Features of TAP-independent MHC class I ligands revealed by quantitative mass spectrometry.
2008
TAP is responsible for transferring cytosolic peptides into the ER, where they can be loaded onto MHC molecules. Deletion of TAP results in a drastic reduction of MHC class I surface expression and alters the presented peptide pattern. This key molecule in antigen processing is tackled by several viruses and lost in some tumors, rendering the altered cells less vulnerable to T cell-based immune surveillance. Using the TAP-deficient cell line LCL721.174 and its TAP-expressing progenitor cell line LCL721.45, we identified and quantified more than 160 HLA ligands, 50 of which were presented TAP-independently. Peptides which were predominantly presented on the TAP-deficient LCL721.174 cell line…
Refolding of the integral membrane protein light-harvesting complex II monitored by pulse EPR
2009
The major light-harvesting chlorophyll a / b complex (LHCII) of the photosynthetic apparatus in plants self-organizes in vitro. The recombinant apoprotein, denatured in dodecyl sulfate, spontaneously folds when it is mixed with its pigments, chlorophylls, and carotenoids in detergent solution, and assembles into structurally authentic LHCII in the course of several minutes. Pulse EPR techniques, specifically double-electron-electron resonance (DEER), have been used to analyze protein folding during this process. Pairs of nitroxide labels were introduced site-specifically into recombinant LHCII and shown not to affect the stability and function of the pigment-protein complex. Interspin dist…