Search results for " LAB"
showing 10 items of 2393 documents
Relaciones laborales y participación sindical: expansión y crisis
2012
El presente número monográfico de Arxius se presenta como una revisión sistemática de los cambios registrados en la Comunidad Valenciana en las dos últimas décadas. Es en este marco en el que se sitúa el análisis que seguidamente se aporta sobre la evolución de las relaciones laborales y la participación sindical que toma como punto de referencia las consideraciones sobre el tema ya realizadas para el período anterior y publicadas en el volumen colectivo La sociedad valenciana de los 90 (García Ferrando, 1992), con objeto de identificar y evaluar en su caso los procesos de expansión y cambio acumulados en dichos ámbitos, con especial referencia al impacto de los más recientes procesos de cr…
La auditoría sociolaboral como herramienta para la gestión de las Relaciones Laborales
2013
En el presente texto presentamos la auditoría sociolaboral como un instrumento de futuro clave para la gestión de los recursos humanos y las relaciones laborales en las organizaciones en el contexto actual. Auditoría entendida como la herramienta capaz de generar los indicadores ¿datos e informaciones- suficientes en cantidad y calidad para afrontar adecuadamente el proceso de toma de decisiones. Pero para que esta herramienta aporte todas sus ventajas, materialice todos sus beneficios para la organización, es necesaria la superación de resistencias existentes en la misma (desconocimiento, miedos y creencias falsas que tienen las organizaciones) y que se conviertan en aspectos clave para su…
La auditoria sociolaboral: una herramienta por descubrir (y utilizar)
2014
Auditoriaren erabilerak erakundeetan, giza baliabideen kudeaketarako tresna gisa, ziurgabetasuna besterik ez du sortu bere eraginkortasunarengan. 2012an Valentziako Unibertsitateko Soziologia eta Gizarte Antropologia sailak hasitako ikerketa batek errealitate hori berretsi du eta agerian jarri du egungo erakundeek kontrol, analisi, ikasketa edo ikerkuntza barne prozesuei auditoria prozesu deitzeko dituzten erresistentziak. Ikerketak azaltzen dituen zailtasunen artetik batek bereziki deitu du gure arreta: noiz baiezta dezakegu erakunde baten gaineko auditoria egiten ari garela? Hori aztertu, ikasi edo ikertzen dugun bakoitzean? Zein betekizun behar ditu analisi, ikerketa edo ikerkuntza proze…
Agile methodologies in times of pandemic: acquisition of employment skills in higher education
2022
PurposeThis research aims to focus on analysing the opinion of university students on the effects that agile methodologies are having on their education during this time of pandemic that is affecting the normal functioning of on-site universities. Specifically, the authors intend to analyse the effect that different constructs have on the development of their skills for labour markets through the application of agile methodologies in blended learning. Thus, the authors will analyse the effects of intrinsic motivation, the interactivity of the system, the involvement of students, their engagement to these activities and their level of satisfaction with this training process.Design/methodolog…
Chemiluminescence response of ß-glucan stimulated leukocytes isolated from different tissues and peritoneal cavity of Dicentrarchus labrax
2003
Abstract The respiratory burst of leukocytes isolated from sea bass ( Dicentrarchus labrax ) pronephros, peritoneal cavity (P.C.), spleen and blood, was measured by a chemiluminescence (CL) assay after stimulation with β-glucan. The CL response by P.C. and pronephros leukocytes was significantly higher than that expressed by a similar number of cells separated from spleen and blood. This probably reflects the observation that the proportion of macrophages and neutrophils was highest in the populations of leukocytes from peritoneal cavity and pronephros. Comparative observations showed a higher degree of yeast phagocytosis by leukocytes taken from peritoneal cavity than the pronephros. Moreo…
Confinement stress in sea bass (Dicentrarchus labrax) depresses peritoneal leukocyte cytotoxicity
2002
Fish respond to stressful conditions via neuroendocrine responses (primary response) which result in increased levels of plasma cortisol which is considered immunosuppressive. Sea bass were confined at low (10 kg/m3) and high (60 kg/m3) density for 3-48 h. Plasma cortisol and glucose were evaluated and two principal cellular immune responses were assayed. A significant increase in plasma cortisol and glucose levels, as well as osmolarity, was found following stress. In addition, phagocytic activity, as shown by reactive oxygen species (ROS) production by challenged head kidney phagocytes and cytotoxic activity of eosinophilic granule cells from peritoneal cavity against K562 tumour cell lin…
PGC-1α signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina.
2013
Retinal ganglion cells (RGCs), used as a common model of central nervous system injury, are particularly vulnerable to metabolic and oxidative damage. However, molecular mechanisms underlying this sensitivity have not been determined in vivo . PGC-1α (encoded by PPARGC1A ) regulates adaptive metabolism and oxidative stress responses in a tissue- and cell-specific manner. Aberrant PGC-1α signaling is implicated in neurodegeneration, but the mechanism underlying its role in central nervous system injury remains unclear. We provide evidence from a mouse model that PGC-1α expression and activity are induced in adult retina in response to metabolic and oxidative challenge. Deletion of Ppargc1a d…
Preclinical Retinal Neurodegeneration in a Model of Multiple Sclerosis
2012
Neurodegeneration plays a major role in multiple sclerosis (MS), in which it is thought to be the main determinant of permanent disability. However, the relationship between the immune response and the onset of neurodegeneration is still a matter of debate. Moreover, recent findings in MS patients raised the question of whether primary neurodegenerative changes can occur in the retina independent of optic nerve inflammation. Using a rat model of MS that frequently leads to optic neuritis, we have investigated the interconnection between neurodegenerative and inflammatory changes in the retina and the optic nerves with special focus on preclinical disease stages. We report that, before manif…
Phosphodiesterase inhibition induces retinal degeneration, oxidative stress and inflammation in cone-enriched cultures of porcine retina.
2013
nherited retinal degenerations affecting both rod and cone photoreceptors constitute one of the causes 74 of incurable blindness in the developed world. Cyclic guanosine monophosphate (cGMP) is crucial in the 75 phototransduction and, mutations in genes related to its metabolism are responsible for different retinal 76 dystrophies. cGMP-degrading phosphodiesterase 6 (PDE6) mutations cause around 4e5% of the retinitis 77 pigmentosa, a rare form of retinal degeneration. The aim of this study was to evaluate whether phar- 78 macological PDE6 inhibition induced retinal degeneration in cone-enriched cultures of porcine retina 79 similar to that found in murine models. PDE6 inhibition was induced…
AISF position paper on liver transplantation and pregnancy: Women in Hepatology Group, Italian Association for the Study of the Liver (AISF)
2016
After the first successful pregnancy in a liver transplant recipient in 1978, much evidence has accumulated on the course, outcomes and management strategies of pregnancy following liver transplantation. Generally, liver transplantation restores sexual function and fertility as early as a few months after transplant. Considering that one third of all liver transplant recipients are women, that approximately one-third of them are of reproductive age (18-49 years), and that 15% of female liver transplant recipients are paediatric patients who have a >70% probability of reaching reproductive age, the issue of pregnancy after liver transplantation is rather relevant, and obstetricians, paedi…