Search results for " Laboratory"

showing 2 items of 622 documents

Infection-induced chromatin modifications facilitate translocation of herpes simplex virus capsids to the inner nuclear membrane

2021

Herpes simplex virus capsids are assembled and packaged in the nucleus and move by diffusion through the nucleoplasm to the nuclear envelope for egress. Analyzing their motion provides conclusions not only on capsid transport but also on the properties of the nuclear environment during infection. We utilized live-cell imaging and single-particle tracking to characterize capsid motion relative to the host chromatin. The data indicate that as the chromatin was marginalized toward the nuclear envelope it presented a restrictive barrier to the capsids. However, later in infection this barrier became more permissive and the probability of capsids to enter the chromatin increased. Thus, although …

virusesGene ExpressionVirus ReplicationPathology and Laboratory Medicineherpes simplex -virusChlorocebus aethiopsCapsidsMedicine and Health SciencesSimplexvirusBiology (General)Mass DiffusivityStainingChromosome BiologyPhysicsChromatinChemistryMedical MicrobiologyViral PathogensPhysical SciencesVirusesHerpes Simplex Virus-1EpigeneticsCellular Structures and OrganellesPathogenskapsidiResearch ArticleHerpesvirusesNuclear EnvelopeQH301-705.5Biological Transport ActiveViral StructureResearch and Analysis MethodsinfektiotMicrobiologydiffuusio (fysikaaliset ilmiöt)CapsidNuclear MembraneVirologyGeneticsAnimalsherpesviruksetVero CellsMicrobial PathogensCell NucleusChemical PhysicsOrganismsBiology and Life SciencesHerpes SimplexCell Biologybiochemical phenomena metabolism and nutritionRC581-607Viral ReplicationHerpes Simplex VirusNuclear StainingSpecimen Preparation and TreatmentImmunologic diseases. AllergyDNA viruses
researchProduct

La grammaire à l’école élémentaire française : un enseignement sous tension…

2022

La question de l’enseignement de la langue à l’école reste sensible en France et entraine régulièrement des débats et des controverses qui dépassent le cadre scolaire. La grammaire cristallise ces oppositions tant au niveau linguistique, didactique et pédagogique, politique, institutionnel, social… Nous sommes de fait face à un enseignement sous tension. Notre proposition tentera d’interroger et de croiser deux dimensions, les savoirs prescrits et les savoirs enseignés. Cette mise en interaction se fera selon deux axes: sur un axe diachronique, nous proposerons une analyse de quelques textes institutionnels qui se succèdent depuis vingt ans pour comprendre les attentes ministérielles dans u…

“UNESCO:CIENCIAS DE LAS ARTES Y LAS LETRAS”Linguistics and Languagepronoms anafòricsdiscovery-learninglaboratori de gramàticaexplicit knowledge of languagegrammar laboratoryanaphoric pronounsaprenentatge per descobrimentLanguage and Linguisticsconeixement explícit de la llenguaCaplletra. Revista Internacional de Filologia
researchProduct