Search results for " Lamin"
showing 8 items of 148 documents
Practical Strategies for Stable Operation of HFF-QCM in Continuous Air Flow
2013
Currently there are a few fields of application using quartz crystal microbalances (QCM). Because of environmental conditions and insufficient resolution of the microbalance, chemical sensing of volatile organic compounds in an open system was as yet not possible. In this study we present strategies on how to use 195 MHz fundamental quartz resonators for a mobile sensor platform to detect airborne analytes. Commonly the use of devices with a resonant frequency of about 10 MHz is standard. By increasing the frequency to 195 MHz the frequency shift increases by a factor of almost 400. Unfortunately, such kinds of quartz crystals tend to exhibit some challenges to obtain a reasonable signal-to…
Variable kinematics models for multilòayered smart plates
2015
Families of layer-wise and equivalent single layer advanced finite elements for the geometrically nonlinear analysis of smart multilayered plates are formulated in a unified framework. The proposed modeling strategy reduces the multifield problems to an effective mechanical plate by the condensation of the electromechanical state into the plate kinematics, which is assumed as a variable order expansion along the plate thickness. Numerical results are presented to validate the proposed modeling approach and finite elements and to investigate their features.
Remodeling Pattern of Spinal Canal after Full Endoscopic Uniportal Lumbar Endoscopic Unilateral Laminotomy for Bilateral Decompression: One Year Repe…
2022
Objective: There is limited literature on repetitive postoperative MRI and clinical evaluation after Uniportal Lumbar Endoscopic Unilateral Laminotomy for Bilateral Decompression. Methods: Clinical visual analog scale, Oswestry Disability Index, McNab’s criteria evaluation and MRI evaluation of the axial cut spinal canal area of the upper end plate, mid disc and lower end plate were performed for patients who underwent single-level Uniportal Lumbar Endoscopic Unilateral Laminotomy for Bilateral Decompression. From the evaluation of the axial cut MRI, four types of patterns of remodeling were identified: type A: continuous expanded spinal canal, type B: restenosis with delayed expansio…
Experimental Investigation on Stiffness and Strength of Single-Lap Z-Pinned Joints in a Laminated CFRP Stress-Ribbon Strip
2016
Carbon fiber-reinforced polymer (carbon-polymer) is an advanced lightweight composite material with high strength and excellent resistance to corrosion and fatigue. Over the past decades, application of fiber-reinforced polymers has been spread from the aerospace to other branches of industry such as automobile and civil engineering. Unidirectional carbon-polymers have a high potential for replacing steel in tensile members. Recently, the first carbonpolymer stress-ribbon bridge has been constructed in Germany. The non-laminated strip-loop carbon-polymer thin strips were used as the load bearing components in this bridge. In comparison with the laminated components, the applied cables are c…
Two-dimensional materials: from hybrid magnetic multilayers to superconducting single layers
2013
El trabajo descrito en esta tesis se encuadra en el ámbito de los materiales laminares con propiedades magnéticas de interés empleados como sistemas químicamente versátiles. En cuanto a su versatilidad química, los materiales laminares constituyen un ejemplo clásico de lo que se denomina una estructura anfitrión, capaz de albergar por intercalación otras especies químicas en su interior de forma mas o menos ordenada. Dos son las familias de compuestos estudiadas en este trabajo: los hidróxidos dobles laminares (layered double hydroxides, LDHs) que exhiben un comportamiento magnético químicamente modulable y los dicalcogenuros de los metales de transición (transition metals dichalcogenides, …
A Quantitative Analysis of the Thermoelastic Effect in CFRP Composite Materials
2010
In this study the thermoelastic signal from carbon fibre-reinforced plastic (CFRP) laminates is investigated. A comparison between the theoretical and experimental values of the thermoelastic signal is reported, with the theoretical predictions obtained from two different quantitative models. These models are based on the classic thermoelastic effect law extended to the case of orthotropic materials (by using the mesomechanical or bulk approach), and the modified law assuming that the surface resin-rich layer behaves as a strain witness of the laminate. It is found that the theoretical predictions of the two models can be strongly and differently influenced by the intrinsic orthotropy of ca…
The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress.
2021
Summary: Chromatin organization plays a crucial role in tissue homeostasis. Heterochromatin relaxation and consequent unscheduled mobilization of transposable elements (TEs) are emerging as key contributors of aging and aging-related pathologies, including Alzheimer’s disease (AD) and cancer. However, the mechanisms governing heterochromatin maintenance or its relaxation in pathological conditions remain poorly understood. Here we show that PIN1, the only phosphorylation-specific cis/trans prolyl isomerase, whose loss is associated with premature aging and AD, is essential to preserve heterochromatin. We demonstrate that this PIN1 function is conserved from Drosophila to humans and prevents…
Progressive non-linear damage of variable angle tow composite plates by a Ritz approach
2022
In this work a Ritz model for progressive non-linear damage analysis of variable angle tow composite plates is presented. The damage is treated in the framework of continuum damage mechanics and its evolution is based on a linear softening law with which four damage indices are computed for degrading the mechanical properties of the material. A set of analyses have been carried out to investigate how damage evolves in VAT composite plates under progressive loading.