Search results for " Large"

Efficacy and safety of yttrium 90 ibritumomab tiuxetan in patients with relapsed or refractory diffuse large B-cell lymphoma not appropriate for auto…

2007

A prospective, multicenter, nonrandomized phase 2 trial was conducted to evaluate the efficacy and safety of a single dose of yttrium-90 (90Y) ibritumomab tiuxetan in elderly patients in first relapsed or primary refractory diffuse large B-cell lymphoma (DLBCL) ineligible for stem-cell transplantation. Patients had been previously treated with chemotherapy (group A, n = 76) or chemotherapy plus rituximab (group B, n = 28). Patients in group A were further divided into patients in whom induction therapy had failed (stratum AI, n = 33) and patients who had relapsed after achieving complete response (CR; stratum AII, n = 43). The overall response rate (ORR) was 52% and 53% in strata AI and AII…

Lymphoma occurring in patients over 90 years of age: characteristics, outcomes, and prognostic factors. A retrospective analysis of 234 cases from th…

2013

International audience; BACKGROUND: Lymphoma occurring in patients aged 90 or older is not uncommon, and its incidence is expected to increase over time. Management of these patients is difficult given their underlying fragility and the lack of information regarding this population. PATIENTS AND METHODS: We retrospectively analyzed 234 patients diagnosed with lymphoma at the age of 90 years or older (90+) between 1990 and 2012 to describe their characteristics, management, outcomes and prognostic factors. RESULTS: The median age was 92 years; 88% were B-cell lymphomas consisting mainly in diffuse large B-cell lymphoma. The median overall survival (OS) was 7.2 months (range, 0-92 months) for…

Long-lasting remission of primary hepatic lymphoma and hepatitis C virus infection achieved by the alpha-interferon treatment

2004

Primary hepatic lymphoma is a rare but well-defined lymphoma entity that often pursues an aggressive clinical course. Most cases have been described in hepatitis C virus (HCV)-related chronic liver disease patients. Although anthracycline-based chemotherapy has been reported to be highly effective, the best therapeutic strategy has not been defined yet. The prognosis is dismal especially in patients treated with chemotherapy alone or when an advanced liver disease is present. Herein, we describe a case of primary hepatic large B-cell non-Hodgkin’s lymphoma, in a patient with HCV chronic infection. After a minor response with eight cycles of CHOP chemotherapy, a complete and sustained remiss…

Prognostic factors in a large multi-institutional series of papillary renal cell carcinoma.

2011

OBJECTIVES To investigate cancer-related outcomes and prognostic factors of papillary renal cell carcinoma (pRCC) in a large multicentre data set. Oncological outcome and prognostic factors of pRCC have been limitedly evaluated in comparison with the most common RCC subtype, clear cell RCC. PATIENTS AND METHODS From a multicentre retrospective database, including 5463 patients who were surgically treated for RCC at 16 Italian academic centres between 1995 and 2007, 577 patients with pRCC were identified. Univariable and multivariable Cox regression models were performed to identify prognostic factors predictive of recurrence-free survival (RFS) and cancer-specific survival (CSS) after surge…

Large deflection of magneto-electro-elastic laminated plates

2014

Abstract A model for the large deflection analysis of magneto-electro-elastic laminated plates is derived. The first order shear deformation theory and the von Karman stress function approach are employed. A set of resolving partial differential equations involving kinematical variables and the stress function is obtained as a consequence of the preliminary condensation of the electro-magnetic state to the plate kinematics. A closed form solution for simply-supported plates is presented. Numerical results are carried out for plates consisting of piezoelectric BaTiO 3 and piezomagnetic CoFe 2 O 4 layers. These results show the influence of large deflections on the plate response and could be…

VET workers’ problem-solving skills in technology-rich environments: European approach

2014

International journal for research in vocational education and training 1 (2014) 1, S. 57-80

Convergence in critical fuel moisture and fire weather thresholds associated with fire activity in the pyroregions of Mediterranean Europe

2021

Wildfires are becoming an increasing threat to many communities worldwide. There has been substantial progress towards understanding the proximal causes of increased fire activity in recent years at regional and national scales. However, subcontinental scale examinations of the commonalities and differences in the drivers of fire activity across different regions are rare in the Mediterranean zone of the European Union (EUMed). Here, we first develop a new classification of EUMed pyroregions, based on grouping different ecoregions with similar seasonal patterns of burned area. We then examine the thresholds associated with fire activity in response to different drivers related to fuel moist…

Musiikillinen aikakokemus Steve Reichin sävellyksessä Music for a Large Ensemble

2006

Update of the search for supersymmetric particles in scenarios with Gravitino LSP and Sleptons NLSP

2001

An update of the search for sleptons, neutralinos and charginos in the context of scenarios where the lightest supersymmetric particle is the gravitino and the next-to-lightest supersymmetric particle is a slepton, is presented, together with the update of the search for heavy stable charged particles in light gravitino scenarios and Minimal Supersymmetric Standard Models. Data collected in 1999 with the DELPHI detector at centre-of-mass energies around 192, 196, 200 and 202 GeV were analysed. No evidence for the production of these supersymmetric particles was found. Hence, new mass limits were derived at 95% confidence level.

Photon events with missing energy at root s=183 to 189 GeV

2000

The production of single photons has been studied in the reaction e+e- -> gamma + invisible particles at centre-of-mass energies of 183 GeV and 189 GeV. A previously published analysis of events with multi-photon final states accompanied by missing energy has been updated with 189 GeV data. The data were collected with the DELPHI detector and correspond to integrated luminosities of about 51 pb^{-1} and 158 pb^{-1} at the two energies. The number of light neutrino families is measured to be 2.84 +/- 0.15(stat) +/- 0.14(syst). The absence of an excess of events beyond that expected from Standard Model processes is used to set limits on new physics as described by supersymmetric and compos…