Search results for " Left"

showing 10 items of 417 documents

2015

The execution of unilateral hand contractions before performance has been reported to produce behavioral aftereffects in various tasks. These effects have been regularly attributed to an induced shift in activation asymmetry to the contralateral hemisphere produced by the contractions. An alternative explanation proposes a generalized state of reduced bilateral cortical activity following unilateral hand contractions. The current experiment contrasted the above explanation models and tested the state of cortical activity after the termination of unilateral hand contractions. Twenty right-handed participants performed hand contractions in two blocks, one for each hand. Using electroencephalo…

Multidisciplinarymedicine.diagnostic_testContralateral hemisphereAlpha (ethology)ElectroencephalographyBiologyUnilateral leftmedicine.anatomical_structureHemispheric asymmetryScalpmedicinemedicine.symptomNeuroscienceMotor cortexMuscle contractionPLOS ONE
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Association between biomarkers of inflammation and left ventricular hypertrophy in moderate chronic kidney disease.

2007

Aims: Left ventricular hyper- trophy (LVH) is a predictor for cardiovascu- lar mortality, and it is considered to be a surro- gate marker of preclinical cardiovascular dis- ease. This study aimed at evaluating whether fetuin-A plasma levels are decreased in pa- tients with moderate chronic kidney disease (CKD) and their linkage to plasma concentra- tions of hs-C-reactive protein (CRP), cardio- trophyn-1 (CT-1), tumor necrosis factor- (TNF-), propeptide of collagen Type I (PIP) and to LVH. Material and methods: We enrolled 64 moderate CKD and 55 essential hypertensives (EH) with normal renal func- tion as controls. All the patients underwent an echocardiographic examination; plasma sam- ples…

NephrologyAdultMalePhosphopeptidesmedicine.medical_specialtyInflammationEnzyme-Linked Immunosorbent AssayLeft ventricular hypertrophyMuscle hypertrophyinflammation left ventricular hypertrophy chronic kidney diseaseStatistical significanceInternal medicineMedicineHumansMass indexcardiovascular diseasesInflammationAnalysis of Variancebusiness.industryTumor Necrosis Factor-alphaCase-control studyGeneral MedicineMiddle Agedmedicine.diseaseEndocrinologyC-Reactive ProteinNephrologyEchocardiographyCase-Control StudiesCardiologyCytokinesKidney Failure ChronicRegression AnalysisFemaleHypertrophy Left Ventricularalpha-Fetoproteinsmedicine.symptombusinessBiomarkersProcollagenKidney diseaseClinical nephrology
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The Risk of Toxicities from Trastuzumab, Alone or in Combination, in an Elderly Breast Cancer Population

2013

<b><i>Background:</i></b> Breast cancer in the elderly is associated with high recurrence and death rates, due mostly to undertreatment. Human epidermal growth factor receptor type 2 (HER2) overexpression is infrequent in older patients. Trastuzumab-based chemotherapy is often withheld from elderly patients because of its cardiotoxicity. <b><i>Patients and Methods:</i></b> Medical records of consecutive HER2-positive breast cancer patients aged ≥70 years old treated between 2005 and 2010 in the participating centers were retrospectively reviewed. All patients underwent multidimensional geriatric assessment (MGA). <b><i>Results:<…

OncologyCancer Researchmedicine.medical_specialtyAnthracyclineSettore MED/06 - Oncologia MedicaReceptor ErbB-2medicine.medical_treatmentPopulationAntineoplastic AgentsBreast NeoplasmsAntibodies Monoclonal HumanizedVentricular Function LeftBreast cancer; Elderly patients; Human epidermal growth factor receptor type 2; TrastuzumabBreast cancerBreast cancerTrastuzumabInternal medicinemedicineHumansAdverse effecteducationGeriatric AssessmentAgedRetrospective StudiesAged 80 and overChemotherapyCardiotoxicityeducation.field_of_studybusiness.industryRetrospective cohort studyGeneral MedicineTrastuzumabmedicine.diseaseHuman epidermal growth factor receptor type 2OncologyFemalebusinessElderly patientmedicine.drugOncology
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The evaluation of root fracture with cone beam computed tomography (CBCT) : an epidemiological study

2018

Background The aim of this study was evaluation of the cone-beam computed tomography (CBCT) image of 50 patients at the ages of 8-15 suspecting root fracture and root fracture occurred, exposed to dental traumatic. In additionally, this study was showed effect of crown fracture on root fracture healing. Material and methods All of the individuals included in the study were obtained images with the cone-beam computed tomography range of 0,3 voxel and 8.9 seconds.(i-CAT®, Model 17-19, Imaging SciencesInternational, Hatfield, Pa USA).The information obtained from the history and CBCT images of patients were evaluated using chi-square test statistical method the mean and the distribution of the…

OrthodonticsCone beam computed tomographybusiness.industrymedicine.medical_treatmentResearch030206 dentistryBone healing:CIENCIAS MÉDICAS [UNESCO]Crown (dentistry)Community and Preventive Dentistry030218 nuclear medicine & medical imagingMandibular central incisorConventional radiography03 medical and health sciencesstomatognathic diseases0302 clinical medicinestomatognathic systemMaxillary left lateral incisorUNESCO::CIENCIAS MÉDICASFracture (geology)MedicineMaxillary central incisorbusinessGeneral Dentistry
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Anterior teeth root inclination prediction derived from digital models: A comparative study of plaster study casts and CBCT images

2018

Background To assess the accuracy of digital models generated using commercially available software to predict anterior teeth root inclination characteristics and compare the results to relevant data obtained from CBCT images. Material and Methods Following sample size calculation and after application of inclusion and exclusion criteria, pre-treatment maxillary and mandibular plaster models and the corresponding CBCT scans of 31 patients attending a private orthodontic clinic were selected. The subjects were 10 males and 21 females with age range 12 to 40 years. Plaster models were scanned using the high resolution mode of an Ortho Insight 3D scanner and CBCT scans were taken using a Kodak…

OrthodonticsScannerbusiness.industryRadiographyResearchRoot (chord)Orthodontics030206 dentistry:CIENCIAS MÉDICAS [UNESCO]03 medical and health sciences0302 clinical medicineSoftwarestomatognathic systemSample size determinationUpper left canineUNESCO::CIENCIAS MÉDICASMaxillary central incisor030212 general & internal medicine10. No inequalitybusinessGeneral DentistryAnterior teethMathematicsJournal of Clinical and Experimental Dentistry
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Oxidant stress and endothelial activation in hypertensive patients with and without left ventricular hypertrophy

2006

Oxidant stress endothelial activation hypertension left ventricular hypertrophy
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Lepton Number Violation in Higgs Decay at LHC

2015

We show that within the Left-Right symmetric model, lepton number violating decays of the Higgs boson can be discovered at the LHC. The process is due to the mixing of the Higgs with the triplet that breaks parity. As a result, the Higgs can act as a gateway to the origin of heavy Majorana neutrino mass. To assess the LHC reach, a detailed collider study of the same-sign di-leptons plus jets channel is provided. This process is complementary to the existing nuclear and collider searches for lepton number violation and can probe the scale of parity restoration even beyond other direct searches.

Particle physicsPhysics::Instrumentation and DetectorsPhysics beyond the Standard ModelSymmetric modelFOS: Physical sciencesGeneral Physics and AstronomyLepton number violation Higgs Large Hadron Collider left-right symmetryHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)left-right symmetryPhysicsLepton number violationLarge Hadron ColliderPhysicsHigh Energy Physics::PhenomenologyParity (physics)Lepton number3. Good healthMAJORANAHigh Energy Physics - PhenomenologyLepton number violation; Higgs; Large Hadron Collider; left-right symmetryLarge Hadron ColliderHiggs bosonHigh Energy Physics::ExperimentNeutrinoparticle physics ; higgs ; neutrinoHiggHiggsPhysical Review Letters
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Perlecan is critical for heart stability

2008

Aims Perlecan is a heparansulfate proteoglycan found in basement membranes, cartilage, and several mesenchymal tissues that form during development, tumour growth, and tissue repair. Loss-of-function mutations in the perlecan gene in mice are associated with embryonic lethality caused primarily by cardiac abnormalities probably due to hemopericards. The aim of the present study was to investigate the mechanism underlying the early embryonic lethality and the pathophysiological relevance of perlecan for heart function. Methods and results Perlecan-deficient murine embryonic stem cells were used to investigate the myofibrillar network and the electrophysiological properties of single cardiomy…

Patch-Clamp TechniquesPhysiologyMyocardial InfarctionMice TransgenicCell CommunicationPerlecanSarcomereBasement MembraneVentricular Function LeftAdherens junctionExtracellular matrixMicePhysiology (medical)medicineAnimalsMyocytes CardiacCells CulturedEmbryonic Stem CellsBasement membranebiologyCartilageCell DifferentiationHeartAnatomyEmbryonic stem cellCell biologyMice Inbred C57BLcarbohydrates (lipids)Disease Models Animalmedicine.anatomical_structurebiology.proteinFemaleCardiology and Cardiovascular MedicineMyofibrilHeparan Sulfate ProteoglycansCardiovascular Research
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Half-width plots, a simple tool to predict peak shape, reveal column kinetics and characterise chromatographic columns in liquid chromatography: Stat…

2013

Peak profiles in chromatography are characterised by their height, position, width and asymmetry; the two latter depend on the values of the left and right peak half-widths. Simple correlations have been found between the peak half-widths and the retention times. The representation of such correlations has been called half-width plots. For isocratic elution, the plots are parabolic, although often, the parabolas can be approximated to straight-lines. The plots can be obtained with the half-widths/retention time data for a set of solutes experiencing the same kinetics, eluted with a mobile phase at fixed or varying composition. When the analysed solutes experience different resistance to mas…

Peak profiles in chromatography are characterised by their height position width and asymmetry; the two latter depend on the values of the left and right peak half-widths. Simple correlations have been found between the peak half-widths and the retention times. The representation of such correlations has been called half-width plots. For isocratic elution the plots are parabolic although often the parabolas can be approximated to straight-lines. The plots can be obtained with the half-widths/retention time data for a set of solutes experiencing the same kinetics eluted with a mobile phase at fixed or varying composition. When the analysed solutes experience different resistance to mass transfer the plots will be solute dependent and should be obtained with the data for each solute eluted with mobile phases at varying composition. The half-width plots approach is a simple tool that facilitates the prediction of peak shape (width and asymmetry) with optimisation purposes reveal the interaction kinetics of solutes in different columns and characterise chromatographic columns. This work shows half-width plots for different situations in isocratic elution including the use of different flows the effect of temperature the modification of the stationary phase surface by an additive the existence of specific interactions within the column and the comparison of columns. The adaptation to gradient elution is also described. Previous knowledge on half-width plots is structured and analysed to which new results are added.Work (thermodynamics)Column characterisationmedia_common.quotation_subjectKineticsLiquid chromatographyAnalytical chemistryHalf-widthsInteraction kineticsBiochemistryAsymmetryAnalytical ChemistryPeak shapeColumn (typography)Position (vector)Mass transferPhase (matter)media_commonChromatographyElutionChemistryOrganic ChemistryGeneral MedicineModels TheoreticalKineticsPredictionChromatography LiquidJournal of Chromatography A
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Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates.

1994

The relationship between intracellular energy parameters and myocardial O2 consumption (VO2) was studied in control and volume-overloaded hearts perfused with different lipid substrates and over a range of left ventricular work loads. In control hearts, a unique linear relationship between log of cytosolic [ATP]/[ADPf].[Pi] (where [ADPf] is concentration of free ADP) and myocardial VO2 was observed between low and high work loads for both fatty acids studied. In volume-overloaded hearts perfused in the presence of exogenous palmitate, the slope of the relationship between log [ATP]/[ADPf].[Pi] and myocardial VO2 was considerably depressed. It would seem that, under these conditions, much o…

PhosphocreatinePhysiologyRespiratory chainPalmitic AcidCardiomegalyPalmitic AcidsIn Vitro TechniquesVentricular Function LeftPhosphatesAdenosine TriphosphateOxygen ConsumptionPhysiology (medical)RespirationPiAnimalsRespiratory systemRats WistarATP synthasebiologyMyocardiumSubstrate (chemistry)HeartCreatineNADRatsAdenosine DiphosphateCytosolBiochemistrybiology.proteinCaprylatesCardiology and Cardiovascular MedicineEnergy MetabolismIntracellularThe American journal of physiology
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