Search results for " Local"
showing 10 items of 2101 documents
Identification of Trans-Golgi Network Proteins in Arabidopsis thaliana Root Tissue
2014
Knowledge of protein subcellular localization assists in the elucidation of protein function and understanding of different biological mechanisms that occur at discrete subcellular niches. Organelle-centric proteomics enables localization of thousands of proteins simultaneously. Although such techniques have successfully allowed organelle protein catalogues to be achieved, they rely on the purification or significant enrichment of the organelle of interest, which is not achievable for many organelles. Incomplete separation of organelles leads to false discoveries, with erroneous assignments. Proteomics methods that measure the distribution patterns of specific organelle markers along densit…
Understanding the clinical behavior of relapsed colon cancers with microsatellite instability relative to BRAF mutations
2019
Background Microsatellite instable/deficient mismatch repair (MSI/dMMR) metastatic colorectal cancers have been reported to have a poor prognosis. Frequent co-occurrence of MSI/dMMR and BRAFV600E complicates the association. Patients and methods Patients with resected stage III colon cancer (CC) from seven adjuvant studies with available data for disease recurrence and MMR and BRAFV600E status were analyzed. The primary end point was survival after recurrence (SAR). Associations of markers with SAR were analyzed using Cox proportional hazards models adjusted for age, gender, performance status, T stage, N stage, primary tumor location, grade, KRAS status, and timing of recurrence. Results A…
High frequency of BRAF V600E mutation in Iranian population ameloblastomas
2020
Background Ameloblastoma is a common locally invasive but slow-growing neoplasm of the jaws with an odontogenic origin. Association between BRAF V600E mutation and clinicopathologic features and behavior of ameloblastoma remains controversial. This study aimed to evaluate BRAF V600E gene mutation and expression of its related proteins with clinicopathologic parameters in conventional ameloblastoma. Material and Methods 50 Formalin-fixed paraffin-embedded blocks were included in this study. Immunohistochemistry was done using rabbit monoclonal BRAF V600E mutation-specific antibody VE1. Quantitative real-time polymerase chain reaction assay was used for evaluating of BRAF V600E mutation. Resu…
Sviluppo locale: l'indugio tra identità ed emergenza.
2009
Calcifying zooplankton standing stocks and in the North Pacific from the R/V Kilo Moana cruise KM1712
2022
This dataset compiles the standing stocks (ind/m³), the integrated standing stocks (ind/m²) and the integrated CaCO3 standing stocks (mg/m²) for three groups of zooplanktonic calcifying organisms: pteropods, heteropods and foraminifers. The organisms were collected by oblique towing (Ø 0.5 m, 90 μm mesh size, SeaGear mechanical flowmeter) in the North Pacific between Hawaii and the Gulf of Alaska during the R/V Kilo Moana cruise KM1712 in August 2017. The sampling strategy was designed to capture an integrated sample of all foraminifers, pteropods and heteropods from juveniles to adults living throughout the upper water column. Pteropods and heteropods were quantified and shell diameter mea…
Governance in the metropolitan area of Valencia (Spain): an unfinished business
2023
Metropolitan government is still an unfinished business in Spain. An example of this is the metropolitan area of Valencia. The aim of this article is to learn about the process that has led to the current situation of a lack of metropolitan government and to propose actions that will help to make it a reality in the not-too-distant future. To this end, it analyses the history and the current regulations, and it is completed with the opinions and contributions of academics and politicians. The result is that, although there is no political will to include the consolidation of a metropolitan government in Valencia in the current political agenda, it is possible to set in motion initiatives of…
Smart city initiatives, public real estate strategic management and new venture creation.
2015
During the last decade, academics have been involved in an interesting debate around the development of the so called Smart City Initiatives. In the prevailing mind-set, the success of the aforementioned initiatives has been based on pillars like ICT infrastructures, human capital, mobility, environment etc. This chapter focuses on the role played by public property assets within the framework of the Smart City initiatives, with a specific focus on those programs that aim to stimulate the creation of entrepreneurial ecosystem. More in detail, the research provides a theoretical and analytical scheme helping policy makers opt for the most suitable choices relating to the public property port…
Shopping malls as pseudo-public spaces. The shopping mall as an emergent public space in Palermo
2012
Much has been written on the role of public space in contemporary societies, and many scholars agree that public space today is a controversial and arguably critical concept. It may actually seem that even the basic idea of what is or should be ‘public’ is experiencing a deep and troublesome reconsideration, as new forms of privatization slowly but firmly erode its fundaments. Within this conceptual framework, this paper aims at critically analyzing the idea of public space today, with particular attention to the idea of public space as a shopping mall. Characteristics of the Italian way of using shopping malls, and their social and spatial consequences, are investigated and analyzed throug…
Multiple solutions for a Neumann-type differential inclusion problem involving the p(.)-Laplacian
2012
Using a multiple critical points theorem for locally Lipschitz continuous functionals, we establish the existence of at least three distinct solutions for a Neumann-type differential inclusion problem involving the $p(\cdot)$-Laplacian.
An overview on bounded elements in some partial algebraic structures
2015
The notion of bounded element is fundamental in the framework of the spectral theory. Before implanting a spectral theory in some algebraic or topological structure it is needed to establish which are its bounded elements. In this paper, we want to give an overview on bounded elements of some particular algebraic and topological structures, summarizing our most recent results on this matter.