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showing 10 items of 2101 documents
Posterior compartment of the lower leg reconstruction with free functional rectus femoris transfer after sarcoma resection.
2009
A 72-year-old man with the third recurrence of a low-grade liposarcoma of the right lower leg came to our attention seeking limb-salvage surgery. The tumour was removed en bloc with all the superficial posterior compartment of the leg. Appropriate foot flexion was restored by means of a free-functional rectus femoris musculocutaneous flap harvested from the ipsilateral thigh. The patient was kept on a postoperative splint for 6 weeks. Three months after the operation, clinical and elecromyographic signs of reinnervation were observed. The patient was able to walk, run and climb stairs and no donor-site morbidity was observed. Thigh extension was rated M4, comparable to the contralateral thi…
Preoperative radiochemotherapy and radical surgery in comparison with radical surgery alone. A prospective, multicentric, randomized DÖSAK study of a…
1994
Abstract A multicentric, randomized study of squamous cell carcinoma (SCC) of the oral cavity and the oropharynx has been undertaken by DOSAK. The results after radical surgery alone have been compared with the results of combined preoperative radiochemotherapy followed by radical surgery. Patients with primary (biopsy proven) SCC of the oral cavity or the oropharynx with tumor nodes metastasis (TNM) stages T2–4, N0–3, M0 were included in the study. A total of 141 patients were treated by radical surgery alone, whereas 127 patients were treated by radical surgery preceded by preoperative radiochemotherapy. The preoperative treatment consisted of conventionally fractioned irradiation on the …
Time to recurrence is a significant predictor of cancer-specific survival after recurrence in patients with recurrent renal cell carcinoma - Results …
2013
Objectives To assess the prognostic impact of time to recurrence (TTR) on cancer-specific survival (CSS) after recurrence in patients with renal cell carcinoma (RCC) undergoing radical nephrectomy or nephron-sparing surgery. To analyse differences in clinical and histopathological criteria between patients with early and late recurrence. Patients and Methods Of 13 107 patients with RCC from an international multicentre database, 1712 patients developed recurrence in the follow-up (FU), at a median (interquartile range) of 50.1 (25-106) months. In all, 1402 patients had recurrence at ≤5 years (Group A) and 310 patients beyond this time (Group B). Differences in clinical and histopathological…
Intrinsic Subtypes and Gene Expression Profiles in Primary and Metastatic Breast Cancer.
2017
Biological changes that occur during metastatic progression of breast cancer are still incompletely characterized. In this study, we compared intrinsic molecular subtypes and gene expression in 123 paired primary and metastatic tissues from breast cancer patients. Intrinsic subtype was identified using a PAM50 classifier and χ2 tests determined the differences in variable distribution. The rate of subtype conversion was 0% in basal-like tumors, 23.1% in HER2-enriched (HER2-E) tumors, 30.0% in luminal B tumors, and 55.3% in luminal A tumors. In 40.2% of cases, luminal A tumors converted to luminal B tumors, whereas in 14.3% of cases luminal A and B tumors converted to HER2-E tumors. We ident…
Issues of adopting benefits management practices of IT investments in municipalities: A Delphi study in Norway
2007
Author's version of a chapter in Proceedings of the 40th Annual Hawaii International Conference on System Sciences. Also available from the publisher at http://dx.doi.org/10.1109/HICSS.2007.303 The concept of benefits management highlights explicit practices to facilitate benefits realization from information technology (IT) investments, in addition to plain project management focusing on information systems (IS) deliverables as such. This article presents preliminary results from a Delphi study of identifying critical issues to facilitate adoption of benefits management practices in Norwegian municipalities. Three expert panels were established, representing three stakeholder groups within…
Marginalità e bioeconomia per lo sviluppo regionale
2014
La bioeconomia si riferisce ad un sistema che si fonda sull'uso intelligente delle risorse biologiche e rinnovabili provenienti dalla terra e dal mare come input industriali e della produzione di alimenti. La Commissione Europea, facendo seguito al lungo dibattito e al percorso effettuato negli ultimi anni sulla strada della sostenibilità, ha approvato la Strategia per l'innovazione per una crescita sostenibile e una bioeconomia per l'Europa. Il lavoro si propone di approfondire come la marginalità territoriale collegata alle disparità socio-economiche, possa essere elemento di vantaggio per la sfida proposta dalla bioeconomia in aree marginali come la Sicilia che hanno le potenzialità di c…
MARGINALITÀ E BIOECONOMIA PER LO SVILUPPO REGIONALE
2013
L'analisi dell'interazioni fra ecosistema e società assume un ruolo rilevante nello studio del sistema economico. La bioeconomia si riferisce ad un sistema che si fonda sull'uso intelligente delle risorse biologiche e rinnovabili provenienti dalla terra e dal mare come input industriali e della produzione di alimenti e mangimi. La bioeconomia, inoltre, comprende l'uso di rifiuti organici e di processi fondati su bioprodotti per un comparto industriale sostenibile. La Commissione Europa, facendo seguito al lungo dibattito e al percorso effettuato negli ultimi anni sulla strada della sostenibilità , ha approvato la strategia per L' innovazione per una crescita sostenibile: una bioeconomia per…
Non-competitive Elections at the Local Level and the Incumbency Advantage of Mayors – Research Experiences from Poland
2021
The objective of this paper is an attempt to answer if non-competitive elections to commune councils in Poland may be the result of incumbency advantage of mayors. The author assumes, that the effects of incumbency advantage of mayors in influence not only the competition for the office of mayor, but also the entire local political scene. These effects may weaken the competitiveness of elections and lead to the cartelisation of local political scenes. In extreme cases, it may even cause the degeneration of political pluralism and lead to non-competitive elections at both the executive and legislative levels. The paper analyses relationships between the competitiveness of elections at the lo…
Accrual financial reporting in the public sector: is it a reality?
2014
Although modernization of governmental accounting has led to the implementation of accrual financial reporting, budgets in most continental european countries, including spain, continue to be based on cash or modified cash methods. Consequently, cash-based and accrual- based financial information coexist. this may create problems for the full implementation of accrual financial statements. this paper analyzes the differences in practice between the results disclosed in financial and budgetary statements under both bases of accounting in order to identify to what extent accrual accounting has been implemented and to verify whether budgetary and accrual- based financial figures are significan…
Local structure of ball-milled LaNi5 hydrogen storage material by Ni K-edge EXAFS
2010
Abstract Local structure of the nanostructured LaNi5 hydrogen storage alloys, prepared by ball-milling, has been studied using Ni K-edge extended X-ray absorption fine structure spectroscopy. Results indicate that the ball-milling up to 100 h results in the production of nanoparticles characterized by large atomic disorder and slightly reduced unit-cell volume, compared to the bulk LaNi5. High temperature annealing appears to help in partial recovery of atomic order in the ball-milled samples; however, long-time ball-milled samples retain large disorder even after the high temperature annealing. The results suggest that the large disorder and the reduced unit-cell volume might be causing a …