Search results for " Low"
showing 10 items of 972 documents
Über die pharmakologische Prüfung von 2-Skatyl-alkylpyridinen
1968
2-Skatyl-alkylpyridine wurden an verschiedenen isolierten Organen untersucht. Die Substanzen zeigten am isolierten Rattendarm eine kompetitiv-nichtkompetitive anticholinerge Wirkung, am isolierten Meerschweinchendarm eine kompetitiv-nichtkompetitive Antihistaminwirkung. An isolierten Meerschweinchenvorhofen trat nach Gabe der tertiaren 2-Skatyl-alkylpyridine eine durch Atropin aufzuhebende negativ inotrope Wirkung auf, die quartaren Substanzen waren dagegen positiv inotrop wirksam. Die tertiaren Stoffe wirkten blutdrucksenkend, die quartaren bei kleinen Dosen blutdrucksteigernd, bei hoheren Dosen blutdrucksenkend. 2-Skatyl-alkyl-pyridines have been studied on different isolated organs. The …
Multi-Resource Management for Multi-Tier Space Information Networks: A Cooperative Game
2019
With the drastic increase of space information network (SIN) traffic and the diversity of network traffic types, the optimal allocation of the scarce network resources is of great significance for optimizing the SIN system capability. In this paper, we propose a multi-resource management method for multi-tier SIN using the cooperative Nash bargaining solution. Since the original problem is a non-convex problem, we firstly make logarithmic transition, and then find a tightest lower bound function to convert the initial problem into a convex one. In order to carry out the optimal bandwidth and power allocation in SIN, we construct a joint bandwidth and power allocation (JBPA) algorithm. Simul…
Successful Treatment of Catastrophic Antiphospholipid Antibody Syndrome (CAPS) Associated With Splenic Marginal-zone Lymphoma With Low-molecular Weig…
2008
ABSTRACT Case report A 69-year-old woman with splenic marginal-zone lymphoma was admitted with progressive abdominal pain and splenomegaly as the suspected cause of pain. Rituximab treatment (375 mg/m 2 ) had been initiated on the day of admission. Abdominal computerized tomography revealed splenic infarction. Laboratory tests showed elevation of liver enzymes and creatinine, low platelet count, prolonged partial thromboplastin time, and lupus anticoagulant positivity. The diagnosis of catastrophic antiphospholipid antibody syndrome was made. Weight-adjusted low-molecular weight heparin therapy was initiated. Freedom from symptoms and normalization of liver enzymes and creatinine occurred w…
Efficient lower and upper bounds of the diagonal-flip distance between triangulations
2006
There remains today an open problem whether the rotation distance between binary trees or equivalently the diagonal-flip distance between triangulations can be computed in polynomial time. We present an efficient algorithm for computing lower and upper bounds of this distance between a pair of triangulations.
An efficient upper bound of the rotation distance of binary trees
2000
A polynomial time algorithm is developed for computing an upper bound for the rotation distance of binary trees and equivalently for the diagonal-flip distance of convex polygons triangulations. Ordinal tools are used.
Application of a low transition temperature mixture for the dispersive liquid–liquid microextraction of illicit drugs from urine samples
2021
© 2021 by the authors.
The evolution of metazoan α-carbonic anhydrases and their roles in calcium carbonate biomineralization
2014
The carbonic anhydrase (CA; EC 4.2.1.1) superfamily is a class of ubiquitous metallo-enzymes that catalyse the reversible hydration of carbon dioxide. The ?-CA family, present in all metazoan clades, is a key enzyme involved in a wide range of physiological functions including pH regulation, respiration, photosynthesis, and biocalcification. This paper reviews the evolution of the ?-CA family, with an emphasis on metazoan ?-CA members involved in biocalcification. Phylogenetic analyses reveal a complex evolutionary history of ?-CAs, and suggest ?-CA was independently co-opted into a variety of skeleton forming roles (e.g. as a provider of HCO3? ions, a structural protein, a nucleation activ…
Influence of dietary fat and carbohydrates proportions on plasma lipids, glucose control and low-grade inflammation in patients with type 2 diabetes—…
2015
Purpose: The optimal macronutrient composition of the diet for the management of type 2 diabetes is debated, particularly with regard to the ideal proportion of fat and carbohydrates. The aim of the study was to explore the association of different proportions of fat and carbohydrates of the diet—within the ranges recommended by different guidelines—with metabolic risk factors. Methods: We studied 1785 people with type 2 diabetes, aged 50–75, enrolled in the TOSCA.IT Study. Dietary habits were assessed using a validated food-frequency questionnaire (EPIC). Anthropometry, fasting lipids, HbA1c and C-reactive protein (CRP) were measured. Results: Increasing fat intake from <25 to ≥35 % is …
Hepatic and very low-density lipoprotein fatty acids in obese offspring of overfed dams.
2010
The combined effects of developmental programming and high-fat feeding at weaning on fatty acid metabolism of the offspring are not well known. In the present study, we aim at characterizing the influence of maternal and offspring's own diets on liver and very low-density lipoprotein (VLDL) lipids; fatty acid profiles of VLDL and liver phospholipids, triglycerides, and cholesteryl esters; and hepatic enzyme activities. Twenty obese male rats born to cafeteria diet-fed dams and 20 control rats born to control diet-fed dams were selected. At weaning, 10 rats of each group were fed control or cafeteria diet. Obese rats had a significant increase in serum glucose, insulin, leptin, VLDL apolipop…
Plasma glycosphingolipids in diabetics and normals
1975
In diabetic patients with hyperlipoproteinemia type IV the monohexosyl ceramide concentration in blood plasma is significantly elevated. This augmentation can be attributed to an increased monohexosyl ceramide content of the BLDL plasma fraction. In contrast, the di-, tri-, the tetrahexosyl ceramide levels remain within normal limits. In normolipidemic diabetics of comparable age, sex, and weight classes and of comparable metabolic control no elevations of glycolipid fractions could be found. However, patients with primary hyperlipoproteinemia type IV show an increase of monohexosyl ceramide concentrations in blood plasma. Therefore, the augmentation of monohexosyl ceramide levels in plasma…