Search results for " Low"

showing 10 items of 972 documents

Carbohydrate antigen 125: an emerging prognostic risk factor in acute heart failure?

2007

To assess whether circulating levels of carbohydrate antigen 125 (CA125) predict subsequent 6-month all-cause mortality in patients after the index hospitalisation for acute heart failure (HF).Prospective cohort study at a single teaching centre in Spain.529 consecutive patients with acute HF admitted in a single university centre were analysed. In addition to the traditional clinical information, CA125 (U/ml) was measured during the early course of hospitalisation. The independent association between baseline CA125 and mortality was assessed with Cox regression analysis. The follow-up was limited to 6 months.349 (66%) patients showed serum levels of CA12535 U/ml (established cut-off point …

Malemedicine.medical_specialtyendocrine system diseasesCardiac Output LowKaplan-Meier EstimateCohort StudiesRisk FactorsInternal medicineEpidemiologymedicineHumansRisk factorProspective cohort studyAgedProportional Hazards ModelsHeart FailureProportional hazards modelbusiness.industryCase-control studyMiddle AgedPrognosismedicine.diseasefemale genital diseases and pregnancy complicationsSurgeryHospitalizationHeart Failure and CardiomyopathyQuartileCA-125 AntigenCase-Control StudiesHeart failureAcute DiseaseFemaleCardiology and Cardiovascular MedicinebusinessBiomarkersCohort studyHeart
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Clinical magnification and residual refraction after implantation of a double intraocular lens system in patients with macular degeneration

2007

Purpose To evaluate the efficacy of a standard double intraocular lens (IOL) system (IOL-Vip) in patients with low vision and central scotoma due to macular degeneration and assess the predictability of the residual refraction and magnification. Setting Ophthalmology Department, Hospital General Universitario, Valencia, Spain. Methods This interventional prospective noncomparative case series comprised 13 consecutive surgical procedures in 10 patients with central scotoma. Follow-up was 12 months. Evaluation included the difference between preoperative and postoperative best corrected visual acuity (BCVA), refraction, position of the IOLs, endothelial cell density, and occurrence of postope…

Malemedicine.medical_specialtygenetic structuresmedicine.medical_treatmentEye diseaseVisual AcuityVision LowMagnificationIntraocular lensRefraction OcularMacular DegenerationLens Implantation IntraocularOphthalmologyHumansMedicineProspective StudiesScotomaCentral scotomaAgedAged 80 and overLenses IntraocularPhacoemulsificationbusiness.industryMiddle AgedMacular degenerationmedicine.diseaseRefractioneye diseasesSensory SystemsSurgeryOphthalmologyTreatment OutcomeMaculopathyFemaleSurgerysense organsbusinessRetinopathyJournal of Cataract and Refractive Surgery
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Acute dialysis: PMN-elastase as a new parameter for controlling individual anticoagulation with low molecular weight heparin (Fragmin).

1991

Despite the improvements in the development of dialyzer membranes with greater hemocompatibility, an activation of the coagulation system occurs when blood comes into contact with exogenous surfaces. The large number of heparin dosage regimens demonstrate the difficulty to adapt general therapeutic guidelines. Low molecular weight heparin (Fragmin®) was administered as a single bolus dose for anticoagulation during 58 acute dialyses. Anti-Xa-activity, the plasma levels of the lysosomal elastase of the polymorphnuclear granulocytes (“PMN-elastase”) and of the thrombin-antithrombin III-complex (TAT) were measured at hourly intervals. Therapeutic anti-Xa-levels did not show evidence of suffici…

Malemedicine.medical_specialtymedicine.drug_classAntithrombin IIILow molecular weight heparinPharmacologyCritical Care and Intensive Care MedicineRenal DialysismedicineHumansPancreatic elastaseAgedbiologyPancreatic Elastasebusiness.industryElastaseAnticoagulantThrombosisHeparinAcute Kidney InjuryHeparin Low-Molecular-WeightMiddle Agedmedicine.diseaseThrombosisSurgeryCoagulationNeutrophil elastasebiology.proteinFemalebusinessLeukocyte Elastasemedicine.drugPeptide HydrolasesIntensive care medicine
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The control of anti-coagulation in acute dialyses with sensitive laboratory parameters.

1992

In seven patients who had to be dialysed between four and 13 times due to acute renal failure, low molecular weight heparin (LMWH) Fragmin was used for anticoagulation. According to dose-finding studies, 80-90 U kg-1 body weight of LMWH as a single bolus were administered initially, producing dose-related levels of 0.3-1.5 anti-factor Xa U ml-1 in plasma. Apart from the anti-Xa activity in the plasma, the thrombin anti-thrombin III complex (TAT complex) and a fibrin degradation product (D-dimer) were measured as parameters of a coagulation activation. A sufficient anti-coagulation during dialysis was supposed to exist at a normal range (5.0 micrograms l-1 or below) of TAT complex. Pathologi…

Malemedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentClinical BiochemistryAntithrombin IIILow molecular weight heparinPharmacologyFibrin Fibrinogen Degradation ProductsThrombinRenal DialysisD-dimermedicineHumansBlood CoagulationDialysisAgedFibrin degradation productbusiness.industryAnticoagulantExtracorporeal circulationAnticoagulantsGeneral MedicineHeparinAcute Kidney InjuryHeparin Low-Molecular-WeightMiddle AgedSurgerybusinessmedicine.drugFactor Xa InhibitorsPeptide HydrolasesScandinavian journal of clinical and laboratory investigation
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Posterior compartment of the lower leg reconstruction with free functional rectus femoris transfer after sarcoma resection.

2009

A 72-year-old man with the third recurrence of a low-grade liposarcoma of the right lower leg came to our attention seeking limb-salvage surgery. The tumour was removed en bloc with all the superficial posterior compartment of the leg. Appropriate foot flexion was restored by means of a free-functional rectus femoris musculocutaneous flap harvested from the ipsilateral thigh. The patient was kept on a postoperative splint for 6 weeks. Three months after the operation, clinical and elecromyographic signs of reinnervation were observed. The patient was able to walk, run and climb stairs and no donor-site morbidity was observed. Thigh extension was rated M4, comparable to the contralateral thi…

Malemedicine.medical_specialtymedicine.medical_treatmentPosterior compartment of the lower leg reconstruction with free functional rectus femoris transfer after sarcoma resection.LiposarcomaThighSurgical FlapsQuadriceps MuscleMedicineHumansSurgical FlapsCompartment (pharmacokinetics)Anterior compartment of thighAgedLegMuscle Neoplasmsbusiness.industryAnatomyLiposarcomaPlastic Surgery Proceduresmedicine.diseaseLimb SalvageSurgerybody regionsmedicine.anatomical_structureSurgerySarcomaNeoplasm Recurrence LocalbusinessSplint (medicine)ReinnervationJournal of plastic, reconstructiveaesthetic surgery : JPRAS
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A comparison of three different attachment systems for mandibular two-implant overdentures: one-year report.

2009

Background: There is a lack of clinical studies on the self-aligning attachment system (Locator®; Zest Anchors, Inc. homepage, Escondido, CA, USA) for two-implant-retained overdentures in the edentulous mandible. Therefore, a comparison of the Locator with two traditional designs (a rotational gold matrix and a rubber O-ring type) in clinical 1-year use was conducted. MaterialsandMethods: From 2003 to 2007, 60 patients received two Osseotite® TG Standard implants (BIOMET 3i Implant Innovations, Palm Beach Gardens, FL, USA) in the intraforaminal area of the edentulous mandible. The implants were left unloaded for 3.5 months, randomized to three different attachment systems, and loaded throug…

Malemedicine.medical_treatmentDenture Complete LowerDentistryDental AbutmentsOral HealthMandiblelaw.inventionDental AbutmentsRandomized controlled triallawmedicineDenture Precision AttachmentHumansJaw EdentulousProspective StudiesDental implantProspective cohort studyDenture DesignGeneral DentistryDenture RetentionAgedOrthodonticsAged 80 and overDental Implantsbusiness.industryDental prosthesisDental Implantation EndosseousMiddle AgedDenture OverlayDenture RetentionTreatment OutcomeDenture DesignQuality of LifeFemaleImplantDental Prosthesis Implant-SupportedOral SurgerybusinessClinical implant dentistry and related research
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Patient-centered and clinical outcomes of mandibular overdentures retained with the locator system: A prospective observational study

2017

Whether clinical or demographic variables affect the perception of treatment in terms of quality of life and satisfaction is unknown.The purpose of this prospective study was to make an evidence-based assessment of the treatment outcomes (patient- and clinically based) of locator-retained mandibular overdentures.This prospective observational study assessed patients with edentulism who had worn mandibular overdentures supported by 2 implants and retained by the locator system for at least 1 year of functional life (N=80). Medical histories were reviewed, and patients underwent oral examinations. Prosthetic clinical outcomes and patient well-being were registered using the Oral Health Impact…

Malemedicine.medical_treatmentDenture Complete LowerDentistryOral HealthMandibleAffect (psychology)Prosthesis03 medical and health sciences0302 clinical medicinePatient satisfactionQuality of lifeSurveys and QuestionnairesDenture RebasingHumansJaw EdentulousMedicineProspective StudiesDenture DesignProspective cohort studySurvival analysisAgedDental ImplantsEdentulismbusiness.industry030206 dentistryDenture Overlaymedicine.diseaseDenture RetentionSurvival Analysisstomatognathic diseasesTreatment OutcomePatient SatisfactionSpainQuality of LifeFemaleObservational studyDental Prosthesis Implant-SupportedOral Surgerybusiness030217 neurology & neurosurgeryFollow-Up StudiesThe Journal of Prosthetic Dentistry
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Genome-Wide Expression Profiles in Very Low Birth Weight Infants With Neonatal Sepsis

2014

BACKGROUND: Bacterial sepsis is associated with high morbidity and mortality in preterm infants. However, diagnosis of sepsis and identification of the causative agent remains challenging. Our aim was to determine genome-wide expression profiles of very low birth weight (VLBW) infants with and without bacterial sepsis and assess differences. METHODS: This was a prospective observational double-cohort study conducted in VLBW (<1500 g) infants with culture-positive bacterial sepsis and non-septic matched controls. Blood samples were collected as soon as clinical signs of sepsis were identified and before antibiotics were initiated. Total RNA was processed for genome-wide expression an…

Malemedicine.medical_treatmentInfant Premature DiseasesCohort StudiesSepsisSepsisGene expressionHumansInfant Very Low Birth WeightMedicineProspective StudiesGeneGram-Positive Bacterial InfectionsPrincipal Component AnalysisNeonatal sepsisTumor Necrosis Factor-alphabusiness.industryInfant NewbornBacterial Infectionsmedicine.diseaseImmunity InnateReverse transcription polymerase chain reactionLow birth weightEarly DiagnosisCytokinePediatrics Perinatology and Child HealthImmunologyCytokinesFemaleTumor necrosis factor alphamedicine.symptomGram-Negative Bacterial InfectionsTranscriptomebusinessGenome-Wide Association StudySignal TransductionPediatrics
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Global variation in anastomosis and end colostomy formation following left-sided colorectal resection

2019

Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods: This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associ…

Malemodelos logísticosmedicine.medical_treatmenthumanossurgial careColorectal Neoplasmpaíses desarrolladosLogistic regressionoutcomesGlobal Healthurgencias médicas0302 clinical medicinepaíses en desarrolloSurgicalestudios prospectivosColostomy80 and overglobalsurg030212 general & internal medicineProspective StudiesProspective cohort studyMultivariate Analysimediana edadCancerAged 80 and overEmergencieancianoAnastomosis colorectal resection colostomyAnastomosis SurgicalColostomyGeneral MedicineMiddle Agedadultocolostomy; colorectal cancer; human developlment index3. Good healthColo-Rectal Cancertraditional healersElective Surgical Procedures030220 oncology & carcinogenesisFemaleColorectal Neoplasms6.4 Surgerylow incomeCohort studyHumanDeveloped CountrieAdultAdult; Aged; Aged 80 and over; Anastomosis Surgical; Colorectal Neoplasms; Colostomy; Elective Surgical Procedures; Emergencies; Female; Global Health; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Developed Countries; Developing Countriesmedicine.medical_specialtyneoplasias colorrectalesLogistic Modelcancer anastomosis surgical income stomas colostomy procedure colorectal resection end colostomy emergency surgical procedure human development indexdelayAnastomosishuman developlment indexPerforation (oil well)lcsh:Surgerycolorectal cancerAnastomosisGlobalSurg CollaborativeNO03 medical and health sciencesCase mix indexClinical ResearchmedicinecancerHumansanálisis multifactorialDeveloping CountriesAgedemergency abdominal surgery low income surgial care traditional healers cancer mortality outcomes delayElective Surgical Procedurebusiness.industryKirurgiDeveloped Countriesleft colon resection anastomosis end colostomyEvaluation of treatments and therapeutic interventionslcsh:RD1-811Odds ratiomortalitySurgeryProspective StudieLogistic ModelsMultivariate AnalysisSurgeryEmergenciesbusinessDigestive Diseasescolostomíaemergency abdominal surgery
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Effects and underlying mechanisms of unstable shoes on chronic low back pain : a randomized controlled trial

2018

Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://journals.sagepub.com/doi/abs/10.1177/0269215517753972?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=crea Este es el postprint del siguiente artículo: Lisón, JF., Ortega-Santana, B., Antón-Nogués, Á., González-Requena, P., Vera-Hervás, C., Doménech-Fernández, J. et al. (2018). Effects and underlying mechanisms of unstable shoes on chronic low back pain : a randomized controlled trial. Clinical Rehabilitationol. 32, n. 5 (may), pp. 654-662, que se ha publicado de forma definitiva en https://doi.org/10.1177/0269215517753972 This is the pre-peer reviewed ve…

Malemusculoskeletal diseasesmedicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationElectromyographylaw.invention03 medical and health sciencesDisability Evaluation0302 clinical medicineRandomized controlled triallawmedicineHumansIn patientRange of Motion ArticularBackache - Treatment.Spine - Electromyography.Abdominal MusclesChronic pain - Treatment.Lumbar Vertebraemedicine.diagnostic_testbusiness.industryElectromyographyBack MusclesRehabilitation030229 sport sciencesMiddle AgedGaitChronic low back painShoesDolor crónico - Tratamiento.Lumbago - Tratamiento.Orthopedic surgeryPhysical therapyColumna vertebral - Electromiografía.Lumbar spineFemaleChronic PainRange of motionbusinessLow Back Pain030217 neurology & neurosurgery
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