Search results for " Ly"

showing 10 items of 2487 documents

Evaluation of Clotting Factor Concentrates for Treatment of Thrombotic Thrombocytopenic Purpura.

2010

Abstract Abstract 3678 Introduction: Thrombotic thrombocytopenic purpura (TTP) is characterized by microthrombi, hemolytic anemia as well as thrombocytopenia. These symptoms are caused by a decreased activity of the protease ADAMTS13 which cleaves the von Willebrand Factor (VWF), due to mutation of the ADAMTS13-gene or autoantibodies. At the moment, the only available immediate therapy is plasmapheresis with Fresh Frozen Plasma (FFP) which may induce side effects. Therefore an alternative therapy might be the treatment with clotting factor concentrates. Methods: 40 plasma samples were tested, consisting of FFP and solvent/detergent treated plasma, four batches of each blood group; VWF/VIII …

Clotting factorHemolytic anemiamedicine.medical_specialtybiologyChemistrymedicine.medical_treatmentImmunologyAutoantibodyThrombotic thrombocytopenic purpuraCell BiologyHematologymedicine.diseaseBiochemistryADAMTS13EndocrinologyVon Willebrand factorhemic and lymphatic diseasesInternal medicineImmunologymedicinebiology.proteinPlasmapheresisFresh frozen plasmaBlood
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Vascular Microarchitecture of Murine Colitis-Associated Lymphoid Angiogenesis

2009

In permissive tissues, such as the gut and synovium, chronic inflammation can result in the ectopic development of anatomic structures that resemble lymph nodes. These inflammation-induced structures, termed lymphoid neogenesis or tertiary lymphoid organs, may reflect differential stromal responsiveness to the process of lymphoid neogenesis. To investigate the structural reorganization of the microcirculation involved in colonic lymphoid neogenesis, we studied a murine model of dextran sodium sulfate (DSS)-induced colitis. Standard 2-dimensional histology demonstrated both submucosal and intramucosal lymphoid structures in DSS-induced colitis. A spatial frequency analysis of serial histolog…

Colitis LymphocyticPathologymedicine.medical_specialtyHistologyStromal cellLymphoid TissueAngiogenesisBiologyArticleMicrocirculationMicemedicineAnimalsIntestinal MucosaColoring AgentsEcology Evolution Behavior and SystematicsMicrodissectionMicroscopy ConfocalNeovascularization PathologicStaining and LabelingMicrocirculationDextran SulfateHistologyMatrix MetalloproteinasesCapillariesMice Inbred C57BLDisease Models AnimalLymphatic systemRegional Blood FlowCytokinesLymphChemokinesAnatomyIntravital microscopyBiotechnologyThe Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
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Colonization pattern of primary tomato roots by Pseudomonas fluorescens A6RI characterized by dilution plating, flow cytometry, fluorescence, confoca…

2004

Early colonization of primary tomato roots, grown in vitro, by Pseudomonas fluorescens A6RI, introduced by seed bacterization, was monitored for 7 days in three different root zones (zone A, apex+elongation+young hairy zone; zone B, hairy zone; zone C, old hairy zone+collar). Bacterial quantification was assessed by enumeration of (i) colony forming units (cfu) after dilution plating and of (ii) total bacterial cells by flow cytometry. Bacterial distribution and organization in the root zones were analyzed by fluorescence, confocal and scanning electron microscopy. For all sampling dates and zones, the densities of total bacterial cells were significantly higher than those of the cfu. The k…

Colony Count MicrobialPseudomonas fluorescensPseudomonas fluorescensPlant RootsApplied Microbiology and BiotechnologyMicrobiologylaw.inventionFlow cytometry03 medical and health sciencesSolanum lycopersicumlawConfocal microscopyBotanymedicine[SDV.MP] Life Sciences [q-bio]/Microbiology and ParasitologyComputingMilieux_MISCELLANEOUS030304 developmental biologyColony-forming unit0303 health sciencesMicroscopy ConfocalEcologybiologyEpidermis (botany)medicine.diagnostic_test030306 microbiologyFlow Cytometrybiology.organism_classificationApex (geometry)Horticulture[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyMicroscopy FluorescenceMicroscopy Electron ScanningDNS root zoneElectron microscope
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Complement receptors on lymphocytes

1981

Complement component 5Cancer ResearchErythrocytesRosette FormationSheepComplement component 2CD46ChemistryComplement C3General MedicineComplement receptorImmune receptorBurkitt LymphomaComplement factor BCell LineReceptors ComplementClassical complement pathwayOncologyImmunologyAnimalsHumansLymphocytesCFHR5Journal of Cancer Research and Clinical Oncology
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Fault detection for continuous-time switched systems under asynchronous switching

2013

In this chapter, the problem of FD for continuous-time switched systems under asynchronous switching is investigated. The designed FD filter is assumed to be asynchronous with the original systems. Attention is focused on designing a FD filter such that the estimation error between the residual and the fault is minimized in the sense of H ∞ norm. By employing piecewise Lyapunov function and ADT techniques, a sufficient condition for the existence of such a filter is exploited in terms of certain LMIs. Finally, an example is provided to illustrate the effectiveness of the proposed approach.

Computer scienceMechanical EngineeringGeneral Chemical EngineeringBiomedical EngineeringAerospace EngineeringPiecewise lyapunov functionResidualIndustrial and Manufacturing EngineeringFault detection and isolationStuck-at faultControl and Systems EngineeringControl theoryAsynchronous communicationNorm (mathematics)Electrical and Electronic EngineeringInternational Journal of Robust and Nonlinear Control
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Interobserver and intraobserver variability in the radiological assessment of sialolithiasis using cone beam computed tomography

2021

Background Data regarding the inter- and intraobserver variability in the radiological assessment of sialolithiasis using cone beam computed tomography are missing in the current literature. This study assessed the inter- and intraobserver variability in the radiological assessment of sialolithiasis using cone beam computed tomography (CBCT). Material and Methods In 107 patients, 130 salivary glands (65 parotid and 65 submandibular) with clinical signs of obstruction were assessed by four independent observers; 2 residents OMFS and 2 experienced OMFS. The observers analyzed the CBCT images and determined the absence or presence of one or more salivary stones in the affected gland. This proc…

Cone beam computed tomographycone-beam computed tomographyACCURACYSALIVARY STONESSalivary gland calculiSigns and symptomsnon-hodgkin lymphomahivSONOGRAPHYsurvivalstomatognathic systemMedicineHumansParotid GlandGeneral DentistryUNESCO:CIENCIAS MÉDICASOral Medicine and Pathologybusiness.industryResearchBackground dataSignificant differenceCone-beam computed tomographyCBCToral cancerSubmandibular glandobserver variationParotid glandmedicine.anatomical_structureObserver variationOtorhinolaryngologyRadiological weaponSurgeryprognosisbusinessNuclear medicineSIALENDOSCOPYKappa
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Interim 18f-PDGPET for Aggressive Non-Hodgking's Lymphoma: A Systematic Review and Meta-Analysis

2011

Abstract Abstract 5183 Background: The advantage of using interim 18F-fluorodeoxyglucose (FDG) positron-emission tomography (PET) scan in the clinical work-up of patients with non-Hodgkin's lymphoma (NLH) is unclear. Data from meta-analyses are inconclusive, mainly because of the low number of patients evaluated and heterogeneity among studies. New clinical investigations, focused on this topic, have been recently published. We conducted an updated systematic review on the role of 18PDG-PET for the interim evaluation in patients with aggressive lymphomas. Materials and Methods: Medline, Embase, Scopus and Databases were searched for relevant studies through March 2011. We included studies t…

Contingency tablemedicine.medical_specialtybusiness.industryImmunologyMEDLINECell BiologyHematologymedicine.diseaseBiochemistryChemotherapy regimenTreatment failureLymphomaMeta-analysisInternal medicineInterimMedicineNuclear medicinebusinessDiffuse large B-cell lymphomaBlood
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Defining Kawasaki disease and pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in…

2021

Abstract Background There is mounting evidence on the existence of a Pediatric Inflammatory Multisystem Syndrome-temporally associated to SARS-CoV-2 infection (PIMS-TS), sharing similarities with Kawasaki Disease (KD). The main outcome of the study were to better characterize the clinical features and the treatment response of PIMS-TS and to explore its relationship with KD determining whether KD and PIMS are two distinct entities. Methods The Rheumatology Study Group of the Italian Pediatric Society launched a survey to enroll patients diagnosed with KD (Kawasaki Disease Group – KDG) or KD-like (Kawacovid Group - KCG) disease between February 1st 2020, and May 31st 2020. Demographic, clini…

Coronary artery abnormalities; Hypotension; Kawasaki disease; Multisystem inflammatory syndrome associated with coronavirus disease; Myocarditis; Pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection; SARS-CoV-2; Age Distribution; Antirheumatic Agents; Aspirin; C-Reactive Protein; COVID-19; Child; Child Preschool; Coronary Artery Disease; Cough; Diarrhea; Dyspnea; Female; Glucocorticoids; Heart Failure; Humans; Hyperferritinemia; Hypotension; Immunoglobulins Intravenous; Immunologic Factors; Infant; Intensive Care Units Pediatric; Interleukin 1 Receptor Antagonist Protein; Italy; Lymphopenia; Male; Mucocutaneous Lymph Node Syndrome; Myocarditis; Platelet Aggregation Inhibitors; SARS-CoV-2; Shock; Systemic Inflammatory Response Syndrome; Tachypnea; Troponin T; VomitingMalelcsh:Diseases of the musculoskeletal systemcoronary artery abnormalities; hypotension; kawasaki disease; multisystem inflammatory syndrome associated with coronavirus disease; myocarditis; pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection; SARS-CoV-2; age distribution; antirheumatic agents; aspirin; C-reactive protein; COVID-19; child ; preschool; coronary artery disease; cough; diarrhea; yspnea; female; glucocorticoids; heart failure; humans; hyperferritinemia; hypotension; immunoglobulins; intravenous; immunologic factors; infant; intensive care units; pediatric; interleukin 1 receptor antagonist protein; italy; lymphopenia; male; mucocutaneous lymph node syndrome; myocarditis; platelet aggregation inhibitors; SARS-CoV-2; shock; systemic inflammatory response syndrome; tachypnea; troponin T; vomitingMyocarditiCoronary Artery Disease030204 cardiovascular system & hematologySARS-CoV-2 Kawasaki disease Pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection Myocarditis Hypotension Multisystem inflammatory syndrome associated with coronavirus disease Coronary artery abnormalitiesCoronary artery diseaseSettore MED/38 - Pediatria Generale E Specialistica0302 clinical medicineGlucocorticoidImmunologic FactorMultisystem inflammatory syndrome associated with coronavirus diseaseImmunology and AllergyChildCoronary artery abnormalitieFisher's exact testPediatricTachypneabiologylcsh:RJ1-570Antirheumatic AgentImmunoglobulins IntravenousShockPediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infectionSettore MED/38Systemic Inflammatory Response SyndromeIntensive Care UnitsMyocarditisC-Reactive ProteinItalyAntirheumatic AgentsChild PreschoolCohortsymbolsPlatelet aggregation inhibitorFemaleHypotensionIntravenousCoronary artery abnormalitiesHumanResearch ArticleDiarrheamedicine.medical_specialtyMyocarditisVomitingImmunoglobulinsMucocutaneous Lymph Node SyndromeIntensive Care Units Pediatric03 medical and health sciencessymbols.namesakeAge DistributionRheumatologyTroponin TInternal medicineLymphopeniamedicineHumansImmunologic FactorsPreschoolGlucocorticoids030203 arthritis & rheumatologyHeart FailureAspirinKawasaki diseasebusiness.industrySARS-CoV-2Platelet Aggregation InhibitorC-reactive proteinCOVID-19Infantlcsh:Pediatricsmedicine.diseaseSystemic inflammatory response syndromeInterleukin 1 Receptor Antagonist ProteinDyspneaCoughImmunoglobulins IntravenouPediatrics Perinatology and Child Healthbiology.proteinKawasaki diseaseHyperferritinemialcsh:RC925-935businessPlatelet Aggregation InhibitorsPediatric rheumatology online journal
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Miltirone Induces G2/M Cell Cycle Arrest and Apoptosis in CCRF-CEM Acute Lymphoblastic Leukemia Cells

2015

Miltirone (1) is a diterpene quinone extracted from a well-known Chinese traditional herb (Salvia miltiorrhiza). We investigated the cytotoxic effects of miltirone toward sensitive and multidrug-resistant acute lymphoblastic leukemia cell lines. Miltirone inhibited multidrug-resistant P-glycoprotein (P-gp)-overexpressing CEM/ADR5000 cells better than drug-sensitive CCRF-CEM wild-type cells, a phenomenon termed collateral sensitivity. Flow cytometric analyses revealed that miltirone induced G2/M arrest and apoptosis. Furthermore, miltirone stimulated reactive oxygen species (ROS) generation and mitochondrial membrane potential (MMP) disruption, which in turn induced DNA damage and activation…

Cyclin-Dependent Kinase Inhibitor p21ATP Binding Cassette Transporter Subfamily BDNA damagePoly ADP ribose polymeraseCellPharmaceutical ScienceApoptosisSalvia miltiorrhizaAnalytical ChemistryDrug DiscoverymedicineHumansCyclin B1CaspaseMembrane Potential MitochondrialPharmacologyCyclin-dependent kinase 1Molecular StructurebiologyOrganic ChemistryPhenanthrenesPrecursor Cell Lymphoblastic Leukemia-LymphomaMolecular biologyG2 Phase Cell Cycle Checkpointsmedicine.anatomical_structureComplementary and alternative medicineApoptosisCell cultureCaspasesbiology.proteinMolecular MedicineReactive Oxygen SpeciesJournal of Natural Products
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Fluorescent Sensing of Maleate versus Fumarate by a Neutral Cyclohexane Based Thiourea Receptor.

2006

A new cyclohexyl based fluorescent anion receptor, is able to recognize maleate versus fumarate both as their TMA salts. Costero Nieto, Ana Maria, Ana.Costero@uv.es ; Colera Llavata, Manuel, Manuel.Colera@uv.es ; Gaviña Costero, Pablo, Pablo.Gavina@uv.es ; Gil Grau, Salvador, Salvador.Gil@uv.es

CyclohexaneUNESCO::QUÍMICAurologic and male genital diseases:QUÍMICA [UNESCO]Medicinal chemistryCatalysischemistry.chemical_compoundhemic and lymphatic diseasesNeutral cyclohexaneMaterials ChemistryFluorescentOrganic chemistryUNESCO::QUÍMICA::Química orgánicaReceptorneoplasmsAnion receptorThiourea receptorFumarateMaleate:QUÍMICA::Química orgánica [UNESCO]Metals and AlloysGeneral ChemistryGeneral MedicineFluorescenceSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsFluorescent ; Neutral cyclohexane ; Thiourea receptor ; Maleate ; FumarateThioureachemistryCeramics and CompositesChemInform
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