Search results for " MIC"

Detection of natural killer T cells in mice infected with Rickettsia conorii.

2013

Little information is available regarding the role of natural killer T (NKT) cells during the early stage of Rickettsia conorii infection. Herein, C3H/HeN mice were infected with the Malish 7 strain of R. conorii. Splenocytes from these mice were analysed in the early stage of the infection by flow cytometry and compared with uninfected controls. Our results showed an increase in NKT cells in infected mice. Additionally, NKT interleukin (IL)-17(+) cells increased three days after infection, together with a concurrent decrease in the relative amount of NKT interferon (IFN)-γ(+) cells. We also confirmed a higher amount of NK IFN-γ(+) cells in infected mice. Taken together, our data showed tha…

Il Microbiota delle piante, ovvero le piante hanno bisogno dei microrganismi

2017

Le relazioni tra le piante e i fattori ambientali (il clima, i nutrienti, l’acqua, la composizione del suolo, etc) sono da tempo ampiamente studiate. Resta invece ancora molto da capire sul ruolo che la componente biologica del suolo (ci sono oltre cento milioni di cellule microbiche in un grammo di suolo!) ha sullo sviluppo e la salute delle piante. Nella rizosfera soprattutto (la porzione di suolo influenzata dalla presenza di radici), gli essudati radicali favoriscono lo sviluppo di microrganismi (batteri, funghi, protozoi, virus) che interagiscono con le radici e con il suolo nell’influenzare i processi di trasformazione ed assorbimento dei nutrienti, la crescita della pianta e le infez…

Efficacy and safety of photodynamic therapy with RLP068 for diabetic foot ulcers: a review of the literature and clinical experience

2020

This article is the second part of a literature review concerning diabetic foot ulcers (DFUs) and the use of antimicrobial photodynamic therapy (PDT). PDT involves the topical application of a photosensitiser into the tissue, followed by illumination that induces the formation of reactive oxygen species (ROS). PDT provides bacterial inactivation and promotes wound healing, and it can be used to manage the infection and microbial colonisation of DFUs. It has pivotal advantages in comparison with chemotherapeutics, such as no potential to induce resistance, and a wide spectrum of activity. Tetracationic Zn(II) phthalocyanine derivatives have been developed for PDT. Among these, we would like …

Pavement Management System model using a LCCA- microsimulation integrated approach

2014

The maintenance and the rehabilitation of the urban road pavements are not often based on systematic program and scheduling but rather on emergency or on other not identified reasons. Moreover the Life Cycle Cost Analysis (LCCA), the only peculiar procedure for the management pavement, finds its own application for highway and motorway, even if it is possible to search the best investment for the urban interstate and arterials. By the light of the quantity of the involved resources, it seems necessary to define an operative methodology for programming the maintenance and rehabilitation activities for the urban pavement. The paper is oriented towards the development of a multidisciplinary ap…

A multidisciplinary approach using LCCA and micro-simulation 10 model for the management of the urban pavements

2013

The maintenance and the rehabilitation of the urban road pavements are not often based on systematic program and scheduling but rather on emergency or on other not identified reasons. Moreover the Life Cycle Cost Analysis (LCCA), the only peculiar procedure for the management pavement, finds its own application for highway and motorway, even if it is possible to search the best investment for the urban interstate and arterials. By the light of the quantity of the involved resources, it seems necessary to define an operative methodology for programming the maintenance and rehabilitation activities for the urban pavement. The paper is oriented towards the development of a multidisciplinary ap…

Gut microbiome and atrial fibrillation - results from a large population-based study

2023

Background Atrial fibrillation (AF) is an important heart rhythm disorder in aging populations. The gut microbiome composition has been previously related to cardiovascular disease risk factors. Whether the gut microbial profile is also associated with the risk of AF remains unknown. Methods We examined the associations of prevalent and incident AF with gut microbiota in the FINRISK 2002 study, a random population sample of 6763 individuals. We replicated our findings in an independent case–control cohort of 138 individuals in Hamburg, Germany. Findings Multivariable-adjusted regression models revealed that prevalent AF (N = 116) was associated with nine microbial genera. Incident AF (N = 5…

Genome Characterization of natural Saccharomyces hybrids of biotechnological interest

2012

At present, the genus Saccharomyces comprises seven species according to their patterns of breeding. The species boundaries are not clear due to the description of several reticulate events due to introgression and hybridization. In the last decade, new natural hybrids have been described in wine and brewing, such as S. cerevisiae x S. kudriavzevii. Due to new practices in wine and beer production, together with consequences in grape properties due to climatic change, led biotechnological companies to search for new yeast strains. In this context, hybrids have become of importance to biotechnological industries because they show good fermentative performance at low temperatures and produce …

MicroRNAs in Extracellular Vesicles in Sweat Change in Response to Endurance Exercise

2020

Background: To date, microRNAs (miRs) carried in extracellular vesicles (EVs) in response to exercise have been studied in blood but not in non-invasively collectable body fluids. In the present study, we examined whether six exercise–responsive miRs, miRs-21, -26, -126, -146, -221, and -222, respond to acute endurance exercise stimuli of different intensities in sweat. Methods: We investigated the response of miRs isolated from sweat and serum EVs to three endurance exercise protocols: (1) maximal aerobic capacity (VO2max), (2) anaerobic threshold (AnaT), and (3) aerobic threshold (AerT) tests. Sauna bathing was used as a control test to induce sweating through increased body temperature i…

Isolation and characterization of sea urchin P. lividus microbiota from coelomic fluid

2015

Dynamics of soil organic matter pools after agricultural abandonment

2014

Changes of land use from croplands to natural vegetation usually increase Carbon (C) stocks in soil. However, the contribution of old and new C to various pools still is not clearly analyzed.We measured the 13C signature of soil organic carbon (SOC) pools after vegetation change from vineyard (C3) to grassland (C4) under Mediterranean climate to assess the changes of old and new C in total SOC, microbial biomass (MB), dissolved organic C (DOC), and CO2 efflux from soil. Development of the perennial grass Hyparrhenia hirta (C4) on vineyard abandoned for 15 or 35 years ago increased C stocks for 13% and 16%, respectively (in the upper 15 cm). This increase was linked to the incorporation of n…