Search results for " MIC"

Bacterial biofilms: a challenge in the discovery of new anti-infective agents.

2010

The ability to form a biofilm, bacterial communities able to grow on surfaces and surrounded by an extracellular polymeric substance biofilm agents.Our research group focused on discovering of novel chemical agents of potential therapeutic utility in the treatment of staphylococcal biofilm-associatedinfections by screening novel compounds (synthetic or natural). In a recent study, the antistaphylococcalbiofilm activity of pyrrolomycins C,D, F1, F2a, F2b, F3 a family of halogenated pyrroles which are naturally produced byActinosporangium vitaminophylum and of the synthesized related compounds I, II, III were investigated and compared (Schillaci et al, 2010). We also focused on marine inverte…

Vapaus, valtio ja politiikka

2008

Englantilaisen politiikan filosofin Michael Oakeshottin (1901–1990) käsitys vapaudesta ja sen kehittyminen toisen maailmansodan jälkeisistä vuosista aina hänen pääteokseensa On Human Conduct (1975) saakka muodostaa tarinan, jota tässä artikkelissa seurataan. Näinä vuosina hänen tuotantonsa pääpaino oli poliittisessa ajattelussa, joten myös hänen vapauden käsityksensä on suhteutettava tähän. Vapautta voidaan pitää yhtenä politiikan teorian peruskäsitteistä – ideana tai kulmakivenä – ja näin ollen myös Oakeshottia on hyvä verrata aiempiin ja nykyisiin politiikan teorian perinteisiin. peerReviewed

Statistical analysis of the relation between metallic microstructures and mechanical properties

2020

This thesis aims at the development of physical relations between the intricate 3D features of metallic microstructures and the mechanical properties of the material. For understanding which are the microstructural determinants of the resultingmechanical behaviour of metals, a deep quantitative characterisation of the microstructure is needed. The main steps of quantitative characterisation of the microstructures are: identification of the phases distribution and their chemical composition, study of the microstructure morphology (geometrical arrangement of grains, grain boundaries, grain orientations, grain size and grain shape). An accurate description of the microstructure features enrich…

Understanding the microbial biogeography of ancient human dentitions to guide study design and interpretation

2021

AbstractThe oral cavity is a heterogeneous environment, varying in factors such as pH, oxygen levels, and salivary flow. These factors affect the microbial community composition and distribution of species in dental plaque, but it is not known how well these patterns are reflected in archaeological dental calculus. In most archaeological studies, a single sample of dental calculus is studied per individual and is assumed to represent the entire oral cavity. However, it is not known if this sampling strategy introduces biases into studies of the ancient oral microbiome. Here, we present the results of a shotgun metagenomic study of a dense sampling of dental calculus from four Chalcolithic i…

Zróżnicowanie uzębienia u nornika zwyczajnego Microtus arvalis Pallas, 1778 z okolic Częstochowy (Wyżyna Śląska)

2021

An analysis of the diversity in the dentition of the common vole, Microtus arvalis, from three localities near Częstochowa (Panki, Przystajń and Mstów) is provided. Populations from these areas were compared to each other in these terms. The teeth were analyzed – the first lower molar (M1) and the upper third molar of the maxilla (M3). Four basic forms of Simplex, Typica, Duplicata and Variabilis were used to study the diversity of the upper tooth. We developed our own model for studying the differentiation of the lower tooth. The present research and a comparison with literature data confirm that the subspecies M. a. duplicatus does occur in the study area.

Exploring long chain n-alkane metabolism in Gordonia sp. strain SoCg

2011

An Integrated Approach to Skeletal Muscle Health in Aging

2023

A decline in muscle mass and function represents one of the most problematic changes associated with aging, and has dramatic effects on autonomy and quality of life. Several factors contribute to the inexorable process of sarcopenia, such as mitochondrial and autophagy dysfunction, and the lack of regeneration capacity of satellite cells. The physiologic decline in muscle mass and in motoneuron functionality associated with aging is exacerbated by the sedentary lifestyle that accompanies elderly people. Regular physical activity is beneficial to most people, but the elderly need well-designed and carefully administered training programs that improve muscle mass and, consequently, both funct…

Review: Mass spectrometry of surfactant aggregates

2011

In contrast with the enormous amount of literature produced during many decades in the field of surfactant aggregation in liquid, liquid crystalline and solid phases, only a few investigations concerning surfactant self-assembling in the gas phase as charged aggregates have been carried out until now. This lack of interest is disappointing in view of the remarkable theoretical and practical importance of the inherent knowledge. The absence of surfactant–solvent interactions makes it easier to study the role of surfactant–surfactant forces in determining their peculiar self-assembling features as well as the ability of these assemblies to incorporate selected solubilizate molecules. Thus, th…

Sviluppo regionale e marginalità. Aspetti finanziari di realtà economiche in divenire

2012

L'economia dei flussi di cassa è il Leitmotiv di questi anni, e il denaro condiziona i comportamenti individuali e collettivi. Economie tradizionalmente solide entrano in crisi se non riscuotono la fiducia dei mercati, e le famiglie, come le imprese, difficilmente riescono a programmare il proprio futuro senza le risorse finanziarie occorrenti per le proprie attività. Nel complesso periodo che stiamo vivendo, è opinione diffusa che l'uscita dalla crisi economica derivi da cambiamenti epocali nell'organizzazione dei sistemi produttivi e finanziari nonché negli stili di vita, rivisitando il significato stesso di sviluppo economico. In tale contesto la marginalità finanziaria, intesa come vant…

Effects of arbuscular mycorrhizal symbiosis on nitrogen dynamics in Mediterranean agro-ecosystems

2010

Le simbiosi arbuscolo micorriziche (AM) sono formate dai funghi appartenenti al phylum Glomeromicota e piante superiori. Le simbiosi (AM) sono caratterizzate dalla penetrazione attiva del fungo dentro negli spazi intercellulari della cortaccia radicale e dalla formazione di strutture di scambio (chiamate ‘arbuscoli’) all’interno della parere cellulare. Gli arbuscoli sono strutture ramificate formate dal fungo AM all’interno della cellula vegetale invasa e sono indubbiamente gli organi chiave della simbiosi. Durante la loro formazione, la cellula vegetale si trasforma radicalmente. In particolare, la membrana cellulare si invagina e una membrana periarbuscolare con una ampia superficie di sc…