Search results for " MIR"
showing 10 items of 304 documents
Graduació de la promoció 2011 de la Facultat d'Economia
2011
Acte de Graduació i lliurament de premis extraordinaris del curs 2009/2010, De la Facultat d'Economia.
El controlador de movimiento a través de la mirada. Una aproximación hacia la aplicación en un alumno con PCI
2013
Artículo recibido: 11/04/13; evaluado: 15/05/13 - 29/05/13; aceptado: 31/05/13
 ResumenLa utilización de las tecnologías de ayuda en los alumnos con necesidades educativas especiales derivadas de un trastorno motor, es un elemento esencial en su proceso de enseñanza y aprendizaje. Sin embargo, las dificultades en la utilización de dichas tecnologías, deben ser abordadas y mostradas para su conocimiento por aquellos interesados en el tema de la innovación tecnológica, como es el caso del controlador de movimiento a través de la mirada. En la investigación que se presenta, se realizó una revisión bibliográfica y se empleó un diseño de estudio de caso intrínseco, con instrumentos de recog…
Femminismo islamico e cosmopolitismo
2021
The chapter introduces Islamic feminism as a movement with a focus on three study cases from Egypt (Omaima Abou-Bakr), Iran (Ziba Mir-Hosseini), and the United States (Amina Wadud). In my section, I claim that besides being a social commitment, Islamic feminism is a form of moral cosmopolitanism, for it is a global and transnational movement. The advocacy of Islamic feminists is rooted in local contexts, at the same time they are involved in empowering international networks which allow them to meet activists from other domains, enforce their projects, share their experiences and work together for achieving their goals. The name “cosmopolitan Islamic feminist” is not an oxymoron, since it d…
Medicīna (Latvijas Universitātes Raksti; 806. sēj.)
2015
Zvaigžņotā Debess: 2015, Rudens (229)
2015
Latvijas Universitāte
Lesbas meliķu pēdas romiešu lirikā: maģistra darbs
1944
The secularization of Marian miracles in Miquel Peres’ La vida de la Verge Maria
2017
En aquest treball analitze el conjunt de miracles marians inclosos per Miquel Peres en La vida de la sacratíssima Verge Maria (València, N. Spindeler, 1494). Aquest conjunt de miracles no només destaca per la funcionalitat concreta que adquireixen en l’estructura de l’obra, sinó perquè, a més, aquests mostren unes característiques determinades que els allunyen de les col·leccions de miracula marians, ja que no presenten alguns dels trets més significatius del gènere. Els miracles de Miquel Peres constitueixen una mostra de la transformació i la secularització del gènere, i ens parlen dels nous usos que se’n deriven i dels nous lectors a qui s’adrecen. In this paper I discuss the whole of Ma…
Transcriptional regulation of miR-224 upregulated in human HCCs by NFκB inflammatory pathways
2012
Background & Aims: miR-224 is up-regulated in human HCCs as compared to both paired peri-tumoral cirrhotic tissues and cirrhotic livers without HCC. Here, we have cloned the miR-224 regulatory region and characterized its transcriptional regulation by the NFκB-dependent inflammatory pathways. Methods: Mature miRNA expression was evaluated by a 2 step stem-loop real-time RT-PCR. The recruitment of polymerase II and transcription factors on the pre-miR-224 promoter has been assessed by ChIPSeq and ChIP. Results: We found miR-224 levels strongly up-regulated in both peri-tumoral cirrhotic livers and HCC samples as compared to normal livers. In silico analysis of the putative miR-224 promoter r…
Quaking and miR-155 interactions in inflammation and leukemogenesis.
2015
Quaking (QKI) is a tumor-suppressor gene encoding a conserved RNA-binding protein, whose expression is downregulated in several solid tumors. Here we report that QKI plays an important role in the immune response and suppression of leukemogenesis. We show that the expression of Qki is reduced in lipopolysaccharide (LPS)-challenged macrophages, suggesting that Qki is a key regulator of LPS signaling pathway. Furthermore, LPS-induced downregulation of Qki expression is miR-155-dependent. Qki overexpression impairs LPS-induced phosphorylation of JNK and particularly p38 MAPKs, in addition to increasing the production of anti-inflammatory cytokine IL-10. In contrast, Qki ablation decreases Fas …
Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells
2015
Pancreatic cancer is currently the fourth most common cancer, is increasing in incidence and soon will be the second leading cause of cancer death in the USA. This is a deadly malignancy with an incidence that approximates the mortality with 44,000 new cases and 36,000 deaths each year. Surgery, although only modestly successful, is the only curative option. However, due the locally aggressive nature and early metastasis, surgery can be performed on less than 20% of patients. Cytotoxic chemotherapy is palliative, has significant toxicity and improves survival very little. Thus new treatment paradigms are needed desperately. Due to the extremely high frequency of KRAS gene mutations (>90%) d…