Search results for " MODELS"

Vaginal infection of mice with HSV type 2 variant ER−: A new animal model for human primary genital HSV type 2 infections

1992

Abstract Studying the pathogenesis of vaginal infections in mice with two variants of Herpes simplex virus type 2 (HSV-2) strain ER we observed that both variants ER+ and ER− caused severe vaginitis but only ER+ invaded the CNS leading to lethal neurological disease. In contrast, mice infected with ER− cleared the virus from the vagina and recovered from infection. ER+ and ER− expressed equal levels of thymidine kinase (TK) indicating a TK-independent difference in neurovirulence. Using the non-neurovirulent variant ER−, we were able to investigate humoral immune responses late after infection. Vaginal infection with ER− suppressed serum antibody formation after a secondary systemic HSV-1 i…

Mouse models of cytomegalovirus latency: overview.

2002

Abstract Background: The molecular regulation of viral latency and reactivation is a central unsolved issue in the understanding of cytomegalovirus (CMV) biology. Like human CMV (hCMV), murine CMV (mCMV) can establish a latent infection in cells of the myeloid lineage. Since mCMV genome remains present in various organs after its clearance from hematopoietic cells first in bone marrow and much later in blood, there must exist one or more widely distributed cell type(s) representing the cellular site(s) of enduring mCMV latency in host tissues. Endothelial cells and histiocytes are candidates, but the question is not yet settled. Another long debated problem appears to be solved: mCMV establ…

MODELING OF VOLATILITY IN THE ROMANIAN CAPITAL MARKET

2012

This paper aims to analyze the volatility of capital market in Romania by selecting a portfolio of representative indices (BET BET_FI and RASDAQ_C). In this respect, we want to identify the most appropriate model to estimate volatility by using modern econometric tools and useful GARCH models respectively. The study results highlight that EGARCH(1,1) model has managed to eliminate all traces of statistically significant autocorrelation and ARCH effects from the residuals from daily series, giving an accurate image of the Romanian capital market volatility.

Ultraviolet imaging of volcanic plumes: A new paradigm in volcanology

2017

Ultraviolet imaging has been applied in volcanology over the last ten years or so. This provides considerably higher temporal and spatial resolution volcanic gas emission rate data than available previously, enabling the volcanology community to investigate a range of far faster plume degassing processes than achievable hitherto. To date, this has covered rapid oscillations in passive degassing through conduits and lava lakes, as well as puffing and explosions, facilitating exciting connections to be made for the first time between previously rather separate sub-disciplines of volcanology. Firstly, there has been corroboration between geophysical and degassing datasets at ≈1 Hz, expeditin…

The relationships between urbanization and bird functional traits across the streetscape

2023

Publisher Copyright: © 2023 The Authors The urbanization process leads to changes in bird communities’ taxonomic and functional compositions. Highly urbanized areas generally exhibit a reduced number of bird species sharing few functional traits. However, most urban bird studies focused on vegetation patches in temperate cities. In this study, we investigate how urban environmental attributes – noise, height of buildings, and urban vegetation characteristics – modulate species occurrences and the distribution of functional traits across the streetscape of a tropical metropolis. We predicted diverse trait-environment relationships, but that highly urbanized contexts (e.g., noisy streets with…

Predator response to the coloured eyespots and defensive posture of Colombian four‐eyed frogs

2023

Deimatic displays, where sudden changes in prey appearance elicit aversive predator reactions, have been suggested to occur in many taxa. These (often only putative) displays frequently involve different components that may also serve antipredator functions via other mechanisms (e.g., mimicry, warning signalling, body inflation). The Colombian four-eyed frog, Pleurodema brachyops, has been suggested to gain protection against predation through putative deimatic displays where they inflate and elevate the posterior part of their body revealing eye-like colour markings. We exposed stationary artificial frogs to wild predators to test whether the two components (eyespot/colour markings, defens…

Habitat area and local habitat conditions outweigh fragmentation effects on insect communities in vineyards

2022

Fragmentation of habitat, for example by intensive agricultural practices, can be detrimental to local biodiversity. However, it often remains unclear whether such biodiversity declines are caused by loss of habitat area or increased fragmentation, and how habitat quality factors into it. In our study system, vegetated vineyards are typically small, and isolated from one another, potentially limiting the distribution and dispersal of organisms. In a full-factorial experiment of a priori selected vegetated vineyard patches of differing size and fragmentation, we aimed to disentangle the effects of habitat area (area of vegetated vineyards), habitat fragmentation (number of vegetated vineyard…

Learn to Cache: Machine Learning for Network Edge Caching in the Big Data Era

2018

The unprecedented growth of wireless data traffic not only challenges the design and evolution of the wireless network architecture, but also brings about profound opportunities to drive and improve future networks. Meanwhile, the evolution of communications and computing technologies can make the network edge, such as BSs or UEs, become intelligent and rich in terms of computing and communications capabilities, which intuitively enables big data analytics at the network edge. In this article, we propose to explore big data analytics to advance edge caching capability, which is considered as a promising approach to improve network efficiency and alleviate the high demand for the radio resou…

Over-dispersion in Oral Health: The state of art of statistical methodology

2011

Faktoru modeļu priekšrocības ekonomiskās aktivitātes īstermiņa prognozēšanā

2014

Promocijas darba anotācija Pēdējā desmitgadē Latvijas tautsaimniecības attīstība bijusi īpaši svārstīga, kas sarežģīja ekonomiskās politikas lēmumu pieņemšanu ekonomiskās situācijas stabilizēšanai. Lai atvieglotu lēmumu pieņemšanu, ekonomisko aktivitāti īstermiņā var prognozēt ar ekonometriskiem modeļiem. Promocijas darba mērķis ir novērtēt faktoru modeļu priekšrocības ekonomiskās aktivitātes prognozēšanas kontekstā un noteikt Latvijas gadījumā nepieciešamo instrumentu un metožu klāstu īstermiņa prognozēšanai. Promocijas darbā tiek sniegtas atbildes uz faktoru modeļu lietošanas problēmjautājumiem īstermiņa prognozēšanā, kā arī novērtēti daži faktoru modeļu lietošanas aspekti. Faktoru modeļu…