Search results for " MORPHOLOGY"

showing 10 items of 543 documents

Correlation between the visibility of submandibular fossa and mandibular canal cortication on panoramic radiographs and submandibular fossa depth on …

2017

Background To identify a correlation between the submandibular fossa (SF) visibility and mandibular canal (MC) cortication on panoramic image and the depth of SF measured on CBCT and also correlation between the depth of SF and vertical and horizontal location of MC on CBCT. Material and Methods 500 CBCT scans and panoramic radiographs were evaluated. SF depth types were classified as type I ( 3mm) on CBCT. Visibility of SF and the cortication of MC on panoramic radiographs were compared with the depth of SF on CBCT. Distances between MC and mandibular inferior, buccal and lingual cortices were measured. Results No statistically significant correlation was found between radiolucent appearan…

0301 basic medicineMaleCone beam computed tomographyPanoramic RadiographyMandibular NerveRadiographyMandibular nerveMandibular canalSubmandibular fossaMandibleMandibular second molarCone Beam Computed Tomography0302 clinical medicineIntraoperative ComplicationsChildSubmandibular FossaOrthodonticsAged 80 and overbiologyMandiblerespiratory systemCone-Beam Computed TomographyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.anatomical_structureUNESCO::CIENCIAS MÉDICASFemaleOral SurgeryAdultFossaAdolescent03 medical and health sciencesYoung Adultstomatognathic systemRadiography PanoramicmedicineHumansGeneral DentistryAgedRetrospective StudiesDental Implantsbusiness.industryResearch030206 dentistrybiology.organism_classificationstomatognathic diseasesOtorhinolaryngologySurgery030101 anatomy & morphologybusinessMedicina oral, patologia oral y cirugia bucal
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PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability

2020

Small bowel adenocarcinomas (SBAs) are often associated with poor prognosis and have limited therapeutic options. Programmed cell death protein-1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway blockade is an effective treatment in many microsatellite instability-high (MSI-H) solid tumors. We aimed at investigating PD-L1 and PD-1 expression in non-hereditary, non-ampullary SBAs, associated with celiac disease (CeD), Crohn’s disease (CrD), or sporadic, recruited through the Small Bowel Cancer Italian Consortium. We assessed PD-L1 and PD-1 by immunohistochemistry in a series of 121 surgically resected SBAs, including 34 CeD-SBAs, 49 CrD-SBAs, and 38 sporadic SBAs. PD-L1 and PD-1 express…

0301 basic medicineMalePD-L1 - small bowel adenocarcinoma - tumor-infiltrating lymphocytes - microsatellite instabilityPathologyBLOCKADEColorectal cancerLymphocyteSmall bowel adenocarcinomaGastroenterologyB7-H1 AntigenSettore MED/120302 clinical medicineCrohn DiseaseIntestine Smallsmall bowel adenocarcinomaSmall bowel adenocarcinomasMEDULLARY CARCINOMA; MORPHOLOGY; EXPRESSION; BLOCKADE; CANCERbiologymicrosatelliteinstabilityMiddle AgedCANCERmedicine.anatomical_structureMedullary carcinomatumor infiltrating lymphocytes030220 oncology & carcinogenesistumor-infiltrating lymphocytesAdenocarcinomaFemaleMicrosatellite InstabilityPD-L1Adultmedicine.medical_specialtysmall bowel adenocarcinoma tumor-infiltrating lymphocytes microsatelliteinstabilitySettore MED/08 - Anatomia PatologicaAdenocarcinomaMEDULLARY CARCINOMAPD-L1 small bowel adenocarcinomaNOPathology and Forensic Medicine03 medical and health sciencesLymphocytes Tumor-InfiltratingInternal medicinePD-L1expressionIntestinal NeoplasmsBiomarkers TumormedicineHumansPD-L1; small bowel adenocarcinoma; tumor infiltrating lymphocytesPD-L1 in small bowel adenocarcinoma MSI-HSmall bowel adenocarcinoma expression microsatellite instability biomarkersAgedRetrospective Studiesbusiness.industryTumor-infiltrating lymphocytesbiomarkersCancerCorrectionMicrosatellite instabilitymedicine.diseaseCeliac Disease030104 developmental biologybiology.proteinEtiologyMORPHOLOGYbusiness
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Distance of the alveolar antral artery from the alveolar crest. Related factors and surgical considerations in sinus floor elevation

2016

Background In a variable proportion of maxillary sinuses alveolar antral artery is located close to the residual ridge, increasing the chances for haemorrhagic complications during sinus floor elevation procedures. Material and Methods Retrospective observational study of CBCT explorations performed for implant-treatment planning. The upper first molar area was selected for this study. The relative uncertainty (standard deviation of the measurement divided by its mean and expressed as a percentage from 0% to 100%) was chosen for determining the observational errors. For modeling the chances of AAA detection, the generalized additive models (GAM) approach was chosen. Results A total of 240 m…

0301 basic medicineMaleSinus Floor AugmentationDentistrySinus Floor AugmentationSurgical planningMandibular first molar03 medical and health sciences0302 clinical medicinemedicineAlveolar ProcessMaxillaHumansGeneral DentistrySinus (anatomy)AgedRetrospective Studiesgeographygeography.geographical_feature_categorybusiness.industryResearch030206 dentistryArteriesMaxillary SinusMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.anatomical_structureOtorhinolaryngologyRidgeMaxillaUNESCO::CIENCIAS MÉDICASSurgeryCrest030101 anatomy & morphologyOral SurgerybusinessArtery
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Induced post-traumatic apexification: 20 year follow-up and morphological study after new fracture.

2018

Apexification is an endodontic technique used in immature necrotic teeth, the primary goal of which is to induce a calcified barrier in roots with open apices and to promote the continuation of apical root development. A 7-year-old patient with a coronal fracture in a maxillary central incisor was treated with an apexification technique using calcium hydroxide. The apical closure was obtained after one year, then a permanent root canal filling was performed. The tooth was monitored for a period of 20 years, up to when a trauma caused its extraction. The newly formed root was analyzed macroscopically, histologically and through scanning electron microscopy. A morphologically normal root was …

0301 basic medicineMaleTertiary dentineRoot canalDentistryCalcium Hydroxide03 medical and health scienceschemistry.chemical_compoundTooth Fractures0302 clinical medicinestomatognathic systemDental Pulp NecrosisMedicineHumansMaxillary central incisorTooth RootChildDental PulpPulp necrosisCalcium hydroxidebusiness.industryApexification030206 dentistryGeneral MedicineApex (geometry)Root Canal TherapyIncisorstomatognathic diseasesmedicine.anatomical_structurechemistryCoronal planeMicroscopy Electron ScanningApexification030101 anatomy & morphologyAnatomybusinessDevelopmental BiologyFollow-Up StudiesAnnals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
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Variability and reliability of the vastus lateralis muscle anatomy.

2016

The aims of this study are to investigate the variability of the morphological and neurovascular anatomy of the vastus lateralis (VL) muscle and to describe the relationships among its intramuscular partitions and with the other muscles of the quadriceps femoris. Clinical implications in its reliability as a flap donor are also discussed.In 2012, the extra- and intramuscular neurovascular anatomy of the VL was investigated in 10 cadaveric lower limbs. In three specimens, the segmental arterial pedicles were injected with latex of different colors to point out their anastomotic connections. The morphological anatomy was investigated with regard to the mutual relationship of the three muscula…

0301 basic medicineMalebusiness.industryVastus lateralis muscleDissectionquadriceps femoriSettore MED/19 - Chirurgia PlasticaGeneral MedicineAnatomyNeurovascular bundleQuadriceps Muscle03 medical and health sciences0302 clinical medicinevastus lateralisMyocutaneous FlapsCadaverMedicineHumansSurgeryFemale030101 anatomy & morphologyAnatomy030223 otorhinolaryngologyCadaveric spasmbusinessActa chirurgica Belgica
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Multimodal determinants of phase-locked dynamics across deep-superficial hippocampal sublayers during theta oscillations

2020

Theta oscillations play a major role in temporarily defining the hippocampal rate code by translating behavioral sequences into neuronal representations. However, mechanisms constraining phase timing and cell-type-specific phase preference are unknown. Here, we employ computational models tuned with evolutionary algorithms to evaluate phase preference of individual CA1 pyramidal cells recorded in mice and rats not engaged in any particular memory task. We applied unbiased and hypothesis-free approaches to identify effects of intrinsic and synaptic factors, as well as cell morphology, in determining phase preference. We found that perisomatic inhibition delivered by complementary populations…

0301 basic medicineMaleneural circuits.Patch-Clamp TechniquesGeneral Physics and AstronomyAction PotentialsHippocampal formationCell morphologySettore BIO/09 - Fisiologia0302 clinical medicineTheta Rhythmlcsh:ScienceBiophysical modelPhysicsNeurons0303 health sciencesComputational modelMultidisciplinaryBiología molecularPyramidal CellsQDynamics (mechanics)Theta oscillationsFemaleAlgorithmsScienceNeurocienciasModels NeurologicalPhase (waves)Mice TransgenicNeural circuitsGeneral Biochemistry Genetics and Molecular BiologyArticle03 medical and health sciencesGlutamatergicMemory taskAnimalsComputer SimulationRats WistarCA1 Region Hippocampal030304 developmental biologyGeneral ChemistryMice Inbred C57BLKinetics030104 developmental biologySynapseslcsh:QNeuroscience030217 neurology & neurosurgeryBiophysical models
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Evaluation of cytocompatibility of calcium silicate-based endodontic sealers and their effects on the biological responses of mesenchymal dental stem…

2015

Aim To investigate in vitro the cytocompatibility of the calcium silicate-containing endodontic sealers MTA Fillapex and TotalFill BC Sealer on human periodontal ligament stem cells (hPDLSCs) by assaying their biological responses and compare them with that observed when using an epoxy resin-based sealer (AH Plus). Methodology Specimens from the three different endodontic sealers were eluated with culture medium for 24 h. The cytotoxicity of these eluates was evaluated using the MTT assay. In addition, an in vitro scratch wound healing model was used to determine their effects on cell migration. Cell adhesion to collagen type I after treatment with the different sealer eluates was also meas…

0301 basic medicineMineral trioxide aggregateMaterials sciencePeriodontal ligament stem cellsCell SurvivalPeriodontal LigamentCell morphologyAndrologyRoot Canal Filling Materials03 medical and health sciences0302 clinical medicineCell MovementMaterials TestingCell AdhesionHumansMTT assayCytotoxicityGeneral DentistryCells CulturedCell ProliferationCell growthSilicatesStem CellsMesenchymal stem cell030206 dentistryAdhesionCalcium Compounds030104 developmental biologyBiomedical engineeringInternational endodontic journal
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Dental pulp calcifications in prehistoric and historical skeletal remains

2020

Abstract Background The prevalence of hard tissue formations in the dental pulp varies considerably. Beside ageing processes and irritations of the dental pulp, etiological associations with cardiovascular disease and dietary habits have been discussed, which are of particular research interest. The aim of this pilot study is to provide new insights on structural and etiological factors involved in the development of pulp calcifications by investigating skeletal remains from different (pre)historic periods. Methods The jaws of 46 skeletons excavated in central Germany, were examined for the presence of pulp stones using digital volume tomography (DVT). A total of 1122 teeth were examined wi…

0301 basic medicineMolarDental radiographyDental WearDentistryPilot Projects03 medical and health sciencesstomatognathic systemBioarchaeologymedicineAnimalsHumansPulp calcificationsDigital volume tomographyDental Pulpmedicine.diagnostic_testbusiness.industrySmall sampleX-Ray MicrotomographyGeneral MedicineCone-Beam Computed TomographyPulp stoneBody Remainsstomatognathic diseases030104 developmental biologyDental Pulp Calcification030101 anatomy & morphologyAnatomybusinessDevelopmental BiologyAnnals of Anatomy - Anatomischer Anzeiger
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Three-dimensional analysis of the physiological foramen geometry of maxillary and mandibular molars by means of micro-CT.

2017

The aim of this study was to investigate the physiological foramen diameter, shape and distance between physiological and anatomical apex of maxillary and mandibular first and second molars. Accurate knowledge of the physiological foramina morphology; thus, inherent mechanical shaping technical hindrances, is decisive when taking the corresponding root canal final preparation decision. The morphological dimensions of a total of 1727 physiological foramina were investigated by means of micro-computed tomography. Mean narrow and wide (to a high number, oval) diameters of the physiological foramen were 0.24, 0.22 and 0.33 mm and 0.33, 0.31 and 0.42 mm in mesiobuccal (MB), distobuccal (DB) and …

0301 basic medicineMolarThree dimensional analysisRoot canalDecision MakingDentistry610 Medicine & healthIn Vitro TechniquesMandibular first molarMandibular second molar03 medical and health sciencesmaxillary and mandibular molars morphology0302 clinical medicineTooth Apexstomatognathic system10066 Clinic of Conservative and Preventive DentistryForamenmedicineHumansapical constrictionphysiological foramenmicro-computed tomography610 Medicine & healthGeneral DentistryMathematicsbusiness.industryDistobuccalX-Ray Microtomography030206 dentistryMolar3500 General DentistryApex (geometry)030104 developmental biologymedicine.anatomical_structureOriginal ArticleDental Pulp Cavitybusinessfinal apical fileRoot Canal Preparation
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Sensory disturbances of buccal and lingual nerve by muscle compression: a case report and review of the literature

2016

Introduction Several studies on cadavers dissection have shown that collateral branches of the trigeminal nerve cross muscle bundles on their way, being a possible etiological factor of some nerve disturbances. Case Report A 45-year-old man attended to the Temporomandibular Joint and Orofacial Pain Unit of the Master of Oral Surgery and Implantology in Hospital Odontològic of Barcelona University, referring tingling in the left hemifacial región and ipsilateral lingual side for one year, with discomfort when shaving or skin compression. Discussion Several branches of the trigeminal nerve follow a path through the masticatory muscles, being the lingual nerve and buccal nerve the most involve…

0301 basic medicineNervous systemOrofacial painNeuràlgia del trigeminNervi trigeminTrigeminal nerveCase ReportOdontologíaMalalties de la bocaOrofacial pain-TMJD03 medical and health sciencesstomatognathic systemCadavermedicineSistema nerviósGeneral Dentistrymedicine.cranial_nerveLingual nerveTrigeminal nervebusiness.industryAnatomy:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludMasticatory forceTemporomandibular jointDissectionstomatognathic diseasesmedicine.anatomical_structureMouth diseasesUNESCO::CIENCIAS MÉDICAS030101 anatomy & morphologyBuccal nervemedicine.symptombusinessTrigeminal neuralgia
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