Search results for " Major"

showing 10 items of 361 documents

A higher incidence of moult–breeding overlap in great tits across time is linked to an increased frequency of second clutches: a possible effect of g…

2021

The rise of temperatures due to global warming is related to a lengthening of the breeding season in many bird species. This allows more pairs to attempt two clutches within the breeding season, thus finishing their breeding activity later in the season and therefore potentially overlapping these with post–breeding moult. We tested whether this occurred in two Spanish great tit Parus major populations. The proportion of pairs laying second clutches increased from 1 % to 32 % over the study period in one of the populations (Sagunto, 1995–2019), while it did not change in the other (Quintos, 2006–2019; mean 5 %). We did not find any temporal trend for moult start date of late–breeding birds i…

Great titEspañaPopulationZoologyPost–breeding moultEffects of global warmingParus majorSeasonal breederCambio climáticoClimate changeClutcheducationNature and Landscape ConservationParuseducation.field_of_studyCambios fenológicosbiologyIncidence (epidemiology)Global warmingMuda post–nupcialbiology.organism_classificationPhenological changesQL1-991SpainCarbonero comúnAnimal Science and ZoologyZoologyMoultingAnimal Biodiversity and Conservation
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Grundsätzliche Überlegungen zur Problematik der Abbrüche des Trochanter major bei und nach Winkelplattenosteosynthesen

1991

Intra- und postoperative Abbruche des Trochanter major bei der operativen Versorgung von pertrochanteren Femurfrakturen sind keine Seltenheit. In der vorliegenden Arbeit werden die wichtigsten Ursachen dargelegt und Empfehlungen zur Vermeidung dieser Komplikationen gegeben. Ein wichtiger Kritikpunkt beim operativen Zugang ist die allgemein empfohlene, aber vollig uberflussige L-formige Abtrennung des M.-vastus-lateralis-Ursprunges. Den entscheidenden Schwachpunkt stellt jedoch das fur die Einbringung der Implantate notwendige grose Knochenfenster in der lateralen Femurkortikalis dar.

Gynecologymedicine.medical_specialtyPlate osteosynthesisTrochanter majorbusiness.industrymedicineSurgerybusinessUnfallchirurgie
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Experimentelle Untersuchungen zur Schwächung der Stabilität des Trochanter major durch laterale Fensterung

1993

Ubliche 130°-Winkelplatten zur Versorgung huftgelenknaher Femurfrakturen haben den Nachteil, das durch das breite Einschlagfenster die laterale Femurkortikalis an biomechanisch wichtiger und hoch beanspruchter Stelle weitgehend unterbrochen wird; dies fuhrt haufig zu Komplikationen wie Abris des Trochanter major, mangelnde Stabilitat usw. Bei anderen Osteosyntheseverfahren, zum Beispiel der dynamischen Huftschraube, wird ein rundes Loch gebohrt. An zehn Femurpaaren wurde experimentell die Minderung der Stabilitat objektiviert, die durch die laterale Fensterung fur eine Osteosynthese entsteht, wobei die rechteckige Fensterung fur Winkelplatten und die kreisrunde Fensterung fur die dynamische…

Gynecologymedicine.medical_specialtyTrochanter majorbusiness.industrymedicineSurgeryFenestrationbusinessUnfallchirurgie
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Real-world evidence from a European cohort study of patients with treatment resistant depression:Healthcare resource utilization

2022

Journal of affective disorders 298, Part A 442-450 (2022). doi:10.1016/j.jad.2021.11.004 special issue: "Special Issue on Corona Virus / Edited by Allan Young, Ron Acierno, Xiang Yang Zhang"

Healthcare resource utilization Major depressive disorder Observational study Real-world evidence Treatment resistant depressionmedicine.medical_specialtyMajor depressive disorderTreatment resistant depressionCohort StudiesIndirect costsDepressive Disorder Treatment-ResistantHealthcare resource utilization; Major depressive disorder; Observational study; Real-world evidence; Treatment resistant depressionObservational studyHealth careHealthcare resource utilizationmedicineHumansMajor depressive episodeDepression (differential diagnoses)Retrospective StudiesReal-world evidenceDepressive DisorderDepressive Disorder Majorbusiness.industryTreatment-ResistantMajorHealth Care Costsmedicine.diseasePsychiatry and Mental healthClinical PsychologyEmergency medicineMajor depressive disorderObservational studymedicine.symptombusinessHealthcare resource utilization; Major depressive disorder; Observational study; Real-world evidence; Treatment resistant depression; Cohort Studies; Delivery of Health Care; Health Care Costs; Humans; Retrospective Studies; Depressive Disorder Major; Depressive Disorder Treatment-ResistantTreatment-resistant depressionDelivery of Health CareCohort study
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From Spain to Sicily after the Expulsion: Conversos between Economic Networks and the Aristocratic Elite

2018

Abstract This article focuses on a group of conversos families from Spain, who established themselves in Palermo after the Expulsion of the Jews in 1492. There they supported financial activities of the Nazione Catalana and established strong relationships with the local aristocracy. Thanks to this alliance, they managed to avoid persecution by the Spanish Inquisition, “cleanse” their “impure” blood and reach high positions within politics and society: feudal titles, political and financial offices, habits of military orders, ecclesiastical appointments and sometimes even sainthood. Firstly, the paper will give a brief sketch of the phenomenon of conversos in Sicily as well as the activitie…

HistoryHistorymedia_common.quotation_subjectFeudalismSettore M-STO/02 - Storia ModernaAncient historySettore M-STO/07 - Storia Del Cristianesimo E Delle ChiesePoliticsAllianceEliteConversos Sicily Majorca Spanish Inquisition purity of blood Torongi family Fardella family military ordersAristocracyPersecutionmedia_commonJournal of Early Modern History
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Recent results on heavy-ion induced reactions of interest for neutrinoless double beta decay at INFN-LNS

2019

Abstract The NUMEN project aims at accessing experimentally driven information on Nuclear Matrix Elements (NME) involved in the half-life of the neutrinoless double beta decay (0νββ). In this view measurements of Heavy Ion (HI) induced Double Charge Exchange (DCE) reaction cross sections are performed with high-accuracy. In particular, the (18O,18Ne) and (20Ne,20O) reactions are used as tools for β+β+ and β-β- decays, respectively. In the experiments, performed at INFN - Laboratory Nazionali del Sud (LNS) in Catania, the beams are accelerated by the Superconducting Cyclotron (CS) and the reaction ejectiles are detected the MAGNEX magnetic spectrometer. The measured cross sections are challe…

Historyexperimental methodsheavy ion: scatteringQC1-999heavy ion: charge exchange[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]hiukkasfysiikka7. Clean energy01 natural sciencesEducationNuclear physicsdouble-beta decay: (0neutrino)Double beta decay0103 physical sciencesneutrino: mass010306 general physicsnucleus: semileptonic decayPhysics010308 nuclear & particles physicsPhysicsparticle: MajoranaNuclear structurecross section: measuredSpecial classmagnetic spectrometercharge exchangedetector: upgradeneon: nuclideComputer Science Applicationsheavy ion induced double charge exchange reactionsneutrino: MajoranaHeavy ionenergy resolution: highydinfysiikkaCharge exchangeexperimental resultsEPJ Web of Conferences
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Recent results on Heavy-Ion induced reactions of interest for 0νββ decay

2019

An updated overview of recent results on Heavy-Ion induced reactions of interest for neutrinoless double beta decay is reported in the framework of the NUMEN project. The NUMEN idea is to study heavy-ion induced Double Charge Exchange (DCE) reactions with the aim to get information on the nuclear matrix elements for neutrinoless double beta (0νββ) decay. Moreover, to infer the neutrino average masses from the possible measurement of the half- life of 0νββ decay, the knowledge of the nuclear matrix elements is a crucial aspect. Uma visão geral atualizada dos resultados recentes sobre reações induzidas por íons pesados ​​de interesse para o decaimento beta duplo sem neutrinos é relatada na es…

Historymeasurement methodsnuclear matrix elements[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]heavy-ion induced Double Charge Exchange; nuclear matrix elements; neutrinoless double beta decay01 natural sciencesneutrinoless double beta decayEducationNuclear physicsoxygen: nuclidedouble-beta decay: (0neutrino)Double beta decay0103 physical sciencesBeta (velocity)neutrino: mass010306 general physicsNuclear ExperimentPhysicsnucleus: semileptonic decayMeasurement methodoperator: transition010308 nuclear & particles physicsHigh Energy Physics::Phenomenologyparticle: Majoranacharge exchangemagnetic spectrometerBeta decayheavy ionComputer Science Applicationsneon: nuclideheavy-ion induced Double Charge ExchangeHeavy ionHigh Energy Physics::ExperimentNeutrinoCharge exchange
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Hydrogeochemistry and Water Balance in the Coastal Wetland Area of “Biviere di Gela,” Sicily, Italy

2006

In the study area physical and chemical factors control the composition of surface and groundwaters, which in turn determine the water quality of the "Biviere di Gela" lake. These factors combine to create diverse water types which change their compositional character spatially as rainfall infiltrates the soil zone, moves down a topographically defined flow path, and interacts with bedrock minerals. Low-salinity waters, which represent the initial stage of underground circulation, start dissolving calcium carbonate from the local rocks. The progressive increase in salinity, characterized by substantially higher Ca, SO4, Na and Cl concentrations, suggests that dissolution of CaSO4 and NaCl i…

HydrologygeographyEnvironmental Engineeringgeography.geographical_feature_categoryhydrogeochemistry major elements trace elements coastal wetland areaEcological ModelingInfiltration basinWetlandPollutionSettore GEO/08 - Geochimica E VulcanologiaSalinityWater balanceEnvironmental ChemistryPrecipitationWater qualityEutrophicationSurface waterGeologyWater Science and TechnologyWater, Air, and Soil Pollution
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Impaired Th1 responses in mice deficient in Epstein-Barr virus-induced gene 3 and challenged with physiological doses of Leishmania major.

2005

Protection against Leishmania major is dependent on IL-12 release from L. major-infected dendritic cells (DC) that induce IFN-gamma-producing Th1/Tc1 cells. IL-27, a novel member of the IL-12 family, is a heterodimer composed of p28 and IL-12p40-related Epstein-Barr virus-induced gene 3 (EBI3), and was shown to be produced by DC. In this study, we utilized EBI3-deficient mice to investigate the role of IL-27 in leishmaniasis using physiological low-dose infections that mimic natural transmissions. Lesions in EBI3(-/-) mice were significantly larger between weeks 3 and 10 post infection, reaching up to approximately threefold increased lesion volumes compared to wild types. In parallel, derm…

ImmunologyPopulationCD11cLeishmaniasis CutaneousBiologyLesionMinor Histocompatibility AntigensMiceT-Lymphocyte SubsetsmedicineImmunology and AllergyAnimalsLeishmania majorRNA MessengerReceptors CytokineeducationLeishmania majoreducation.field_of_studyEBI3Dendritic cellDendritic CellsTh1 Cellsbiology.organism_classificationImmunologyInterleukin 12Lymphmedicine.symptomEuropean journal of immunology
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Updated insights into the mechanism of action and clinical profile of the immunoadjuvant QS-21: A review

2019

Background Vaccine adjuvants are compounds that significantly enhance/prolong the immune response to a co-administered antigen. The limitations of the use of aluminium salts that are unable to elicite cell responses against intracellular pathogens such as those causing malaria, tuberculosis, or AIDS, have driven the development of new alternative adjuvants such as QS-21, a triterpene saponin purified from Quillaja saponaria. Purpose The aim of this review is to attempt to clarify the mechanism of action of QS-21 through either receptors or signaling pathways in vitro and in vivo with special emphasis on the co-administration with other immunostimulants in new adjuvant formulations, called a…

InflammasomesT-Lymphocytesmedicine.medical_treatmentHerpes zosterPharmaceutical ScienceMonophosphoryl Lipid AAPCs antigen presenting cellsMiceCMI cell mediated immunity0302 clinical medicineDrug DiscoveryHerpes Zoster VaccineMedicineNSCLC non small cell lung carcinomaCancerImmunity CellularVaccines Synthetic0303 health sciencesImmunogenicityIl-2 interleukine 2HIV human immunodeficiency virusLipid A030220 oncology & carcinogenesisCytokinesMolecular MedicineDCs dendritic cellsNK natural killerAdjuvantTLR Toll-like receptorHerpes Zoster VaccineCD cluster of differentiationAntigen-Presenting CellsCTL cytotoxic T lymphocytesHZ herpes zosterMPL 3-deacylated monophosphoryl lipidVaccine adjuvantImmunoadjuvantArticleVZV varicella zoster virus03 medical and health sciencesImmune systemAdjuvants ImmunologicAntigenPAMPs pathogen-associated molecular patternsMalaria VaccinesPRRs pathogen recognition receptorsQS-21 Quillaja saponaria Molina-fraction 21AnimalsMHC major histocompatibility complexMtb Mycobacterium tuberculosis bacteriaSARS severe acute respiratory syndromeAntigen-presenting cellIFN-γ interferon-gamma030304 developmental biologyPharmacologybusiness.industryA-β amyloid-betaTNF-α tumor necrosis factor-alphaSaponinsQS-21MalariaQuillaja saponariaComplementary and alternative medicineTCR T-cell receptorLiposomesImmunologyKLH keyhole limpet hemocyaninbusinessdLN draining lymph nodesMAPK mitogen activated protein kinasePhytomedicine
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