Search results for " Mal"
showing 10 items of 5318 documents
Novità in tema di IOL multifocali.
2008
Value of Combined PET Imaging with [18F]FDG and [68Ga]Ga-PSMA-11 in mCRPC Patients with Worsening Disease during [177Lu]Lu-PSMA-617 RLT
2021
Despite the promising results of prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) in metastatic castration-resistant prostate cancer (mCRPC), some patients show worsening disease during PSMA-RLT. We investigated the value of combined [18F]FDG and [68Ga]Ga-PSMA-11 PET imaging in this setting. In n = 29 mCRPC patients with worsening disease after a median of four cycles of [177Lu]Lu-PSMA-617 RLT, combined [18F]FDG and [68Ga]Ga-PSMA-11 PET imaging was performed to detect [18F]FDG-avid lesions with low or no PSMA expression (mismatch lesions). To evaluate prognostic implication of mismatch, survival analyses regarding presence, location, and [18F]FDG PET-derived para…
La raffigurazione della malattia neuropsichiatrica nell'iconografia barocca ovvero l'interpretazione della fenomenologia mistica nell'arte.
2012
PROTAGONISTI DELLE RAPPRESENTAZIONI DELL'ABUSO ALL'INFANZIA: ATTORI E CONTESTI
2009
RIASSUNTO. Il modello di ricerca-intervento presentato si riferisce ad un’indagine esplorativa sulle rappresentazioni sociali dell’abuso all’infanzia degli operatori delle forze dell’ordine e socio-assistenziali. L’obiettivo è stato, nello specifico, quello di riconoscere eventuali influenze del sistema di credenze, espresse attraverso stereotipi e pregiudizi, nelle valutazioni delle situazioni di abuso. Le variabili sono rappresentate dall’appartenenza ad una specifica professione ( Forze armate, psicologi, pedagogisti, assistenti sociali) e dalla città presso la quale si svolge tale attività lavorativa (Palermo e Trapani). L’analisi svolta è di tipo qualitativo e si basa sulle risposte li…
L’effetto broncodilatatore dell’inspirazione profonda nell’asma
2005
Toisteiset viestit multimodaalien käyttöliittymien suunnitteluperiaatteena
2000
Les médecins et la justice au XVe siècle à travers l'exemple dijonnais
1995
Antitumor Effect of Cabozantinib in Bone Metastatic Models of Renal Cell Carcinoma
2021
Background: The presence of bone metastases in renal cell carcinoma (RCC) negatively affects patients’ survival. Data from clinical trials has highlighted a significant benefit of cabozantinib in bone metastatic RCC patients. Here, we evaluated the antitumor effect of cabozantinib in coculture models of renal cell carcinoma (RCC) and osteoblasts (OBs) to investigate whether and how its antiproliferative activity is influenced by OBs. Methods: Bone/RCC models were generated, coculturing green fluorescent protein (GFP)-tagged Caki-1 and 786-O cells with human primary OBs in a “cell–cell contact” system. RCC proliferation and the OB molecular profile were evaluated after the cabozantinib treat…
La ricerca clinica tra scienza ed etica nella malattia di Parkinson.
2008
Cardiovascular disease: pathophysiological mechanisms
2015
OSA is a common disease that affects approximately 10% of the middle-aged population and becomes more prevalent with age. It is caused by intermittent and repetitive collapse of the UA during sleep. The main acute physiological consequences of OSA are oxygen desaturation, intrathoracic pressure changes and arousals. OSA is associated with significant cardiovascular morbidity and mortality and is an independent risk factor for CVD. The pathogenesis of CVD in OSA is not completely understood but is likely to be multifactorial, involving a diverse range of closely interrelated and detrimental intermediate mechanisms that predispose patients to atherosclerosis, including oxidative stress, sympa…