Search results for " Mal"

showing 10 items of 5318 documents

Long-term outcome of patients with or without osseointegrated implants after resection of mandibular ameloblastoma and reconstruction with vasculariz…

2018

BACKGROUND: The optimal management after the resection of mandibular ameloblastoma has been very challenging to surgeons. The aim of this study is to evaluate the functional, aesthetic, and quality of life outcomes of patients who had a segmental mandibular resection and immediate reconstruction with or without osseointegrated implants. METHOD: Patients' demographics, tumor characteristics, treatment, and complications were retrieved. Patients were divided into two groups: dental rehabilitated vs. nondental rehabilitated depending on the placement of osseointegrated implants followed by an implanted-retained prosthesis. Functional outcomes and quality of life were assessed using the Perform…

AdultMaleRadical treatmentmedicine.medical_specialtyMandibular Ameloblastoma Radical treatment Segmental Resection Fibular flap Dental rehabilitation.AdolescentVisual Analog ScaleVisual analogue scalemedicine.medical_treatmentMandibular OsteotomyMandibular NeoplasmsMandibular AmeloblastomaDental rehabilitation; Fibular flap; Mandibular Ameloblastoma; Radical treatment; Segmental Resection; Adolescent; Adult; Aged; Ameloblastoma; Child; Female; Fibula; Humans; Male; Mandibular Neoplasms; Mandibular Osteotomy; Middle Aged; Osseointegration; Patient Satisfaction; Quality of Life; Surgical Flaps; Visual Analog Scale; Young Adult; Dental Implantation Endosseous; Dental Implants; Mandibular ReconstructionProsthesisOsseointegrationSurgical FlapsAmeloblastoma03 medical and health sciencesYoung Adult0302 clinical medicinePatient satisfactionQuality of lifeOsseointegrationMedicineHumansFibular flapChildAgedSegmental ResectionDental ImplantsPerformance statusbusiness.industryDental Implantation Endosseous030206 dentistryMiddle AgedSurgeryDental ImplantationMandibular NeoplasmsFibulaPatient Satisfaction030220 oncology & carcinogenesisQuality of LifeSurgeryFemaleSegmental resectionMandibular ReconstructionEndosseousbusinessDental rehabilitationJournal of plastic, reconstructiveaesthetic surgery : JPRAS
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Prevalence of peripheral artery disease by abnormal ankle-brachial index in atrial fibrillation: implications for risk and therapy.

2013

AdultMaleRegistrieRiskMiddle AgedPeripheral Arterial Diseaseatrial fibrillation; cardiovascular disease; peripheral vascular disease; Adult; Aged; Atrial Fibrillation; Female; Humans; Internal Medicine; Italy; Male; Middle Aged; Peripheral Arterial Disease; Prevalence; Registries; Risk; Societies Medical; Ankle Brachial Index; Cardiology and Cardiovascular MedicineItalycardiovascular diseaseperipheral vascular diseaseMedicalAtrial FibrillationInternal MedicinePrevalenceHumansFemaleAnkle Brachial IndexRegistriesSocietiesCardiology and Cardiovascular MedicineSocieties MedicalAgedHuman
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Clinical analysis following lumbar interspinous devices implant: where we are and where we go

2014

Objectives:We present our experience with patients treated with interspinous devices who are affected by neurogenic intermittent claudication (NIC) or lumbar disc herniation (LDH) where the interspinous system has been inserted following microdiscectomy.Study design:Retrospective study.Methods:This study included patients (n=100) with NIC secondary to lumbar spinal stenosis (group 1), and patients (n=100) with LDH (group 2) in whom the interspinous device has been implanted following radicular decompression in a period spanning 6 years. The latter have been compared with a homogenous group of patients (n=100) where no interspinous system has been implanted following microdiscectomy (group 3…

AdultMaleReoperationMicrosurgerymedicine.medical_specialtyTime FactorsVisual analogue scaleDecompressionlumbar interspinous devicesAdult Prostheses and Implants Aged Decompression Surgical Disability Evaluation Female Follow-Up Studies Intermittent Claudication Intervertebral Disc Displacement Humans Lumbar Vertebrae Microsurgery Minimally Invasive Surgical Procedures Middle Aged Male Retrospective Studies Pain Measurement Patient Satisfaction Surveys and Questionnaires Reoperation Recurrence Treatment Outcome Spinal StenosisDisability EvaluationSpinal StenosisLumbarRecurrenceSurveys and QuestionnairesmedicineHumansMinimally Invasive Surgical ProceduresAgedPain MeasurementRetrospective StudiesLumbar VertebraeSettore MED/27 - Neurochirurgiabusiness.industryLumbar spinal stenosisProstheses and ImplantsGeneral MedicineIntermittent ClaudicationMiddle AgedDecompression Surgicalmedicine.diseaseIntermittent claudicationOswestry Disability IndexSurgeryTreatment OutcomeNeurologyPatient SatisfactionFemaleNeurology (clinical)Implantmedicine.symptombusinessClaudicationIntervertebral Disc DisplacementFollow-Up StudiesSpinal Cord
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Refined cytogenetic-risk categorization for overall and leukemia-free survival in primary myelofibrosis: a single center study of 433 patients.

2011

We have previously identified sole +9, 13q- or 20q-, as 'favorable' and sole +8 or complex karyotype as 'unfavorable' cytogenetic abnormalities in primary myelofibrosis (PMF). In this study of 433 PMF patients, we describe additional sole abnormalities with favorable (chromosome 1 translocations/duplications) or unfavorable (-7/7q-) prognosis and also show that other sole or two abnormalities that do not include i(17q), -5/5q-, 12p-, inv(3) or 11q23 rearrangement are prognostically aligned with normal karyotype, which is prognostically favorable. These findings were incorporated into a refined two-tired cytogenetic-risk stratification: unfavorable and favorable karyotype. The respective 5-y…

AdultMaleRiskCancer Researchmedicine.medical_specialtyPathologyAdolescentChromosomal translocationmyelofibrosisGastroenterologycytogeneticsDisease-Free SurvivalSettore MED/15 - Malattie Del SangueInternal medicineComplex KaryotypemedicineHumansMyelofibrosisAgedAged 80 and overChromosome AberrationsLeukemiaHematologyPlatelet Countbusiness.industryHazard ratioKaryotypeHematologyMiddle AgedPrognosismedicine.diseaseConfidence intervalkaryotypeOncologyPrimary MyelofibrosisInternational Prognostic Scoring SystemKaryotypingOriginal ArticleFemalemyeloproliferativebusiness
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Association of a dietary score with incident type 2 Diabetes: the dietary-based diabetes-risk score (DDS)

2015

Background Strong evidence supports that dietary modifications may decrease incident type 2 diabetes mellitus (T2DM). Numerous diabetes risk models/scores have been developed, but most do not rely specifically on dietary variables or do not fully capture the overall dietary pattern. We prospectively assessed the association of a dietary-based diabetes-risk score (DDS), which integrates optimal food patterns, with the risk of developing T2DM in the SUN (“Seguimiento Universidad de Navarra”) longitudinal study. Methods We assessed 17,292 participants initially free of diabetes, followed-up for a mean of 9.2 years. A validated 136-item FFQ was administered at baseline. Taking into account prev…

AdultMaleRiskGerontologymedicine.medical_specialtySettore MED/09 - Medicina InternaDiabetes riskAdult; Body Mass Index; Diabetes Mellitus Type 2; Female; Humans; Incidence; Male; Risk; Diet; Agricultural and Biological Sciences (all); Biochemistry Genetics and Molecular Biology (all); Medicine (all)lcsh:MedicineType 2 diabetesChronic diseaseBody Mass IndexInternal medicineType 2 diabetes mellitusHumansMedicineMortalitylcsh:ScienceDietary modificationsBiochemistry Genetics and Molecular Biology (all)Multidisciplinarybusiness.industryProportional hazards modelIncidenceMedicine (all)lcsh:RHazard ratioType 2 Diabetes Mellitusmedicine.diseaseConfidence intervalDietDiabetes Mellitus Type 2Agricultural and Biological Sciences (all)Red meatlcsh:QFemalebusinessBody mass indexResearch ArticleHuman
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The impact of prior TURP on radical prostatectomy surgical margins: A multicenter analysis and members of the mirror study, LUNA foundation

2013

Objective: To analyze positive surgical margins (PSM) after radical prostatectomy (RP) in the overall population and in patients previously treated with transurethral resection of the prostate (TURP). Materials and Methods: 2,408 patients treated with RP for clinically localized prostate cancer (PCa) were consecutively enrolled in 135 departments. We correlated PSM rates and all preoperative, surgical and pathological features. We stratified the site of PSM as unique or multifocal. Moreover, we analyzed differences between 75 patients who had undergone previous TURP and the remaining 2,333 patients. Results: In the entire study population, we identified 702 patients with PSM (29%). Using un…

AdultMaleRiskPrognosiBiopsyUrologyUrinary BladderPositive surgical marginurologic and male genital diseasesAgedAged 80 and overProstatectomyProstate cancerfungiProstateTransurethral Resection of ProstateMiddle AgedProstate-Specific AntigenRadical prostatectomyTransurethral prostate resectionPositive surgical margins; Prostate cancer; Radical prostatectomy; Transurethral prostate resection; Adult; Aged; Aged 80 and over; Biopsy; Humans; Italy; Male; Middle Aged; Neoplasm Grading; Prognosis; Prostate; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Risk; Transurethral Resection of Prostate; Treatment Outcome; Urinary Bladder; UrologyTreatment OutcomeItalyProstatic NeoplasmNeoplasm GradingHuman
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Natural history of mesenteric venous thrombosis in patients treated with vitamin K antagonists: a multi-centre, retrospective cohort study.

2009

summaryKnowledge on the natural history of mesenteric vein thrombosis (MVT) and of the efficacy and safety of long-term oral anticoagulant therapy (OAT) in this setting is based on small uncontrolled series of patients with a limited follow-up. It was the aim of the study to assess the natural history of MVT in a cohort of patients treated with OAT. The charts of all MVT patients currently attending or who have attended four anticoagulation clinics were reviewed. Information on risk factors, treatment, recurrence, major bleeding and mortality was collected. Seventyseven patients (mean age 49.2 years; 45 males) were included with a median follow-up of 36 months (range 2–204 months). Forty-si…

AdultMaleRiskmedicine.medical_specialtyVitamin Kmedicine.drug_classmedicine.medical_treatmentSettore MED/15 - Malattie Del SangueCohort StudiesRisk FactorsmedicineHumansVeinAgedRetrospective StudiesAged 80 and overVenous ThrombosisChemotherapybusiness.industryAnticoagulantAnticoagulantsRetrospective cohort studyHematologyMiddle Agedmedicine.diseaseSurgeryMesenteric ArteriesNatural historyVenous thrombosismedicine.anatomical_structuremesenteric vein thrombosisCohortFemalebusinessCohort study
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Cancer patients requiring interruption of long-term warfarin because of surgery or chemotherapy induced thrombocytopenia: The use of fixed sub-therap…

2012

No data are available regarding the management of cancer patients requiring interruption of long-term vitamin-K antagonist (VKA) therapy. For this purpose, we tested the efficacy and safety of fixed doses of low-molecular weight heparin (LMWH) in substitution of VKA because of invasive procedures or chemotherapy-induced thrombocytopenia. In cancer patients on VKA, therapy was discontinued 5 ± 1 days before surgery or chemotherapy. Heparin was given at prophylactic dosage in patients at low risk and at fixed subtherapeutic doses (3,800 or 4,000 UI anti-FXa, b.i.d.) in those at high-risk for thrombosis. LMWH was reinitiated 12 hr after surgery and VKA the day after. In patients receiving chem…

AdultMaleRiskmedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentLow molecular weight heparinAntineoplastic AgentsHemorrhagelow-molecular weight heparin (LMWH); long-term vitamin-K antagonist (VKA) therapy; cancer patientsSettore MED/15 - Malattie Del SanguePostoperative ComplicationsNeoplasmsThromboembolismAtrial FibrillationHumansThrombophiliaMedicinecancer thrombocytopenia low molecular weight heparinProspective StudiesProspective cohort studyAgedAged 80 and overChemotherapybusiness.industryIncidenceWarfarinAnticoagulantsCancerHematologyHeparinHeparin Low-Molecular-WeightMiddle Agedmedicine.diseaseThrombocytopeniaThrombosisSurgeryClinical trialHeart Valve ProsthesisAnesthesialow-molecular weight heparin (LMWH)FemaleWarfarinlong-term vitamin-K antagonist (VKA) therapycancer patientsbusinessmedicine.drugAmerican Journal of Hematology
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Sacral bladder denervation for treatment of detrusor hyperreflexia and autonomic dysreflexia

2001

Objectives. Detrusor hyperreflexia after spinal cord injury may cause urinary incontinence and chronic renal failure. In patients refractory to conservative treatment and not eligible for ventral sacral root stimulation for electrically induced micturition, we investigated the therapeutic value of sacral bladder denervation as a stand-alone procedure. Methods. Nine patients (8 men and 1 woman) between 21 and 58 years old (mean 30.2) with traumatic suprasacral spinal cord lesions underwent sacral bladder denervation for treatment of detrusor hyperreflexia and/or autonomic dysreflexia. Results. Detrusor hyperreflexia and autonomic dysreflexia were eliminated in all cases. Bladder capacity inc…

AdultMaleSacrumUrologymedicine.medical_treatmentmedia_common.quotation_subjectUrinary systemUrinary BladderUrinary incontinenceQuadriplegiaurologic and male genital diseasesUrinationRhizotomyMuscle HypertoniamedicineHumansSpinal cord injurySpinal Cord Injuriesmedia_commonParaplegiaDenervationLumbar VertebraeReflex Abnormalbusiness.industryUrinary diversionMiddle Agedmedicine.diseasefemale genital diseases and pregnancy complicationsCystostomyTreatment OutcomeUrinary IncontinenceBladder augmentationAnesthesiaUrinary Tract InfectionsAutonomic DysreflexiaFemaleAutonomic dysreflexiamedicine.symptomUrinary CatheterizationbusinessFollow-Up StudiesUrology
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Physical capacity in performing daily activities is reduced in scleroderma patients with early lung involvement

2014

BACKGROUND: Patients with systemic sclerosis (SSc) often complain reduced capacity at submaximal exercise; conversely physical capacity in performing daily duties has never been measured in SSc. OBJECTIVES: To evaluate this performance and its correlates, in patients with SSc compared to healthy controls, in a free-living setting. METHODS: Twenty-seven outpatients with stable SSc and 11 controls were recruited. Physical activity was assessed by portable multiple sensor device (SenseWear Armband) worn for at least six days. Physical activity duration (PAD; in minutes) for non-sedentary activities and physical activity level (PAL= total daily energy/resting energy expenditure) per day were ca…

AdultMaleScleroderma SystemicPhysical activityHypertension PulmonaryMiddle AgedSettore MED/10 - Malattie Dell'Apparato RespiratorioLung functionSclerodermaNutrition AssessmentSpirometryActivities of Daily LivingHumansMotion sensorFemaleExerciseAged
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