Search results for " Maps"

showing 10 items of 198 documents

Protein expression profiling suggests relevance of noncanonical pathways in isolated pulmonary embolism

2019

Abstract Patients with isolated pulmonary embolism (PE) have a distinct clinical profile from those with deep vein thrombosis (DVT)-associated PE, with more pulmonary conditions and atherosclerosis. These findings suggest a distinct molecular pathophysiology and the potential involvement of alternative pathways in isolated PE. To test this hypothesis, data from 532 individuals from the Genotyping and Molecular Phenotyping of Venous ThromboEmbolism Project, a multicenter prospective cohort study with extensive biobanking, were analyzed. Targeted, high-throughput proteomics, machine learning, and bioinformatic methods were applied to contrast the acute-phase plasma proteomes of isolated PE pa…

MaleProteomeDatasets as TopicComorbidity030204 cardiovascular system & hematologyProteomicsBioinformaticsBiochemistryThrombosis and HemostasisMachine LearningPathogenesis0302 clinical medicineProtein-Arginine Deiminase Type 2Prospective StudiesProtein Interaction MapsProspective cohort study0303 health scienceseducation.field_of_studyVenous ThromboembolismHematologyMiddle AgedThrombosisPhenotypePulmonary embolismProteomeN-AcetylgalactosaminyltransferasesFemaleAdultQuantitative Trait LociImmunologyPopulationInterferon-gamma03 medical and health sciencesInterleukin-15 Receptor alpha SubunitmedicineHumansGlial Cell Line-Derived Neurotrophic FactoreducationAged030304 developmental biologybusiness.industryPulmonary SurfactantsCell BiologyAtherosclerosismedicine.diseaseOxidative StressGene Expression RegulationPulmonary EmbolismTranscriptomebusinessAcute-Phase ProteinsFollow-Up StudiesBlood
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Relative Peripheral Myopia Induced by Fractal Contact Lenses

2018

[EN] Purpose: To assess the peripheral refraction induced by Fractal Contact Lenses (FCLs) in myopic eyes by means of a two-dimensional Relative Peripheral Refractive Error (RPRE) map. Materials and Methods: This study involved 26 myopic subjects ranging from -0.50 D to -7.00 D. FCLs prototypes were custom-manufactured and characterized. Corneal topographies were taken in order to assess correlations between corneal asphericity and lens decentration. Two-dimensional RPREs were measured with an open-field autorefractor at 67 points, covering the central 60 x 30 degrees of the visual field. The bidimensional RPRE vector components: M, J(0) and J(45) of the difference between the values obtain…

MaleRefractive errorMaterials sciencegenetic structuresContact LensesRefraction OcularMyopia progressionlaw.inventionCorneaYoung Adult03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineFractalOpticslawMyopiamedicineHumansContact lensesbusiness.industryCorneal TopographyTwo-dimensional mapsmedicine.diseaseRefractioneye diseasesSensory SystemsSagittal planePeripheralVisual fieldLens (optics)OphthalmologyFractalsmedicine.anatomical_structureAutorefractorFISICA APLICADADisease Progression030221 ophthalmology & optometryFemalesense organsVisual FieldsFractalMATEMATICA APLICADAbusiness030217 neurology & neurosurgeryPeripheral refractive errorCurrent Eye Research
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Joint Estimation of Relative Risk for Dengue and Zika Infections, Colombia, 2015–2016

2019

We jointly estimated relative risk for dengue and Zika virus disease (Zika) in Colombia, establishing the spatial association between them at the department and city levels for October 2015–December 2016. Cases of dengue and Zika were allocated to the 87 municipalities of 1 department and the 293 census sections of 1 city in Colombia. We fitted 8 hierarchical Bayesian Poisson joint models of relative risk for dengue and Zika, including area- and disease-specific random effects accounting for several spatial patterns of disease risk (clustered or uncorrelated heterogeneity) within and between both diseases. Most of the dengue and Zika high-risk municipalities varied in their risk distributio…

MaleZika virus diseaseEpidemiologylcsh:MedicineDengue virusmedicine.disease_causeZika virusZika virusDengue feverDengueconditional auto-regressive prior0302 clinical medicineRisk FactorsPrevalence030212 general & internal medicineGeography MedicalChildBayesian modelsbiologyZika Virus InfectionMiddle AgedRandom effects modelmultivariate risk modelsInfectious DiseasesGeographyChild PreschoolFemaleAdultMicrobiology (medical)medicine.medical_specialtyAdolescent030231 tropical medicineColombiaRisk mapsHistory 21st CenturyRisk Assessmentlcsh:Infectious and parasitic diseasesYoung Adult03 medical and health sciencesAge DistributionEnvironmental healthmedicineHumanslcsh:RC109-216Estimationdengue virusResearchPublic healthlcsh:RInfant NewbornInfantBayes Theorembiology.organism_classificationmedicine.diseaseRelative riskEmerging Infectious Diseases
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Striated muscle-specific serine/threonine-protein kinase beta (SPEGβ) segregates with high- versus low-responsiveness to endurance exercise training

2019

Bidirectional selection for either high or low responsiveness to endurance running has created divergent rat phenotypes of high-response trainers (HRT) and low-response trainers (LRT). We conducted proteome profiling of HRT and LRT gastrocnemius of 10 female rats (body weight 279 ± 35 g; n = 5 LRT and n = 5 HRT) from generation 8 of selection. Differential analysis of soluble proteins from gastrocnemius was conducted by label-free quantitation. Genetic association studies were conducted in 384 Russian international-level athletes (age 23.8 ± 3.4 yr; 202 men and 182 women) stratified to endurance or power disciplines. Proteomic analysis encompassed 1,024 proteins, 76 of which exhibited stat…

MaleentsyymitPhysiologykestävyysharjoitteluliquid chromatography mass spectrometryMuscle ProteinslihaksetSerine threonine protein kinaseRC1200Gene Frequencyendurance trainingProtein Interaction MapsliikuntafysiologiaExercise capacityPhenotypeexercise capacitymedicine.anatomical_structureOrgan SpecificityFemalesportsGlycolysisResearch Articlekinaasitmedicine.medical_specialtymassaspektrometriaresponsiveness to exerciseBiologyProtein Serine-Threonine KinasesPolymorphism Single NucleotideYoung Adultartificial selection modelEndurance trainingInternal medicinePhysical Conditioning AnimalGeneticsmedicineAnimalsHumansco‐immunopreciptiationskeletal muscleBeta (finance)Muscle SkeletalQH426Skeletal musclelabel‐free quantitationMuscle StriatedRatsharjoitusvasteEndocrinologyProtein Kinases
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Plasmon Excitations in Mixed Metallic Nanoarrays

2019

Features of the surface plasmon from macroscopic materials emerge in molecular systems, but differentiating collective excitations from single-particle excitations in molecular systems remains elusive. The rich interactions between single-particle electron-hole and collective electron excitations produce phenomena related to the chemical physics aspects within the atomic array. We study the plasmonic properties of atomic arrays of noble (Au, Ag, and Cu) and transition-metal (Pd, Pt) homonuclear chains using time-dependent density functional theory and their Kohn-Sham transition contributions. The response to the electromagnetic radiation is related to both the geometry-dependent confinement…

Materials scienceGeneral Physics and AstronomyFOS: Physical sciences02 engineering and technologyElectronoptiset ominaisuudet01 natural sciencesMolecular physicsElectromagnetic radiationHomonuclear moleculeplasmonicsnanorakenteet0103 physical sciencesMesoscale and Nanoscale Physics (cond-mat.mes-hall)Physics::Atomic and Molecular Clusterstransition contribution mapsGeneral Materials ScienceSurface plasmon resonance010306 general physicsPlasmonCondensed Matter - Materials ScienceCondensed Matter - Mesoscale and Nanoscale Physicsta114Surface plasmontiheysfunktionaaliteoriaGeneral EngineeringMaterials Science (cond-mat.mtrl-sci)molecular plasmonics021001 nanoscience & nanotechnologytime-dependent density-functional theorytime-dependent density functional theorycollective excitationQuasiparticleDensity functional theory0210 nano-technology
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Unmixing of human skin optical reflectance maps by Non-negative Matrix Factorization algorithm

2013

International audience; We present in this paper the decomposition of human skin absorption spectra with a Non-negative Matrix Factorization method. In doing so, we are able to quantify the relative proportion of the main chromophores present in the epidermis and the dermis. We present experimental results showing that we obtain a good estimate of melanin and hemoglobin concentrations. Our approach has been validated by analyzing the human skin absorption spectra in areas of healthy skin and areas affected by melasma on eight patients.

Materials science[ INFO.INFO-TS ] Computer Science [cs]/Signal and Image ProcessingAbsorption spectroscopyMelasmaHealth InformaticsHuman skin02 engineering and technology[ SPI.SIGNAL ] Engineering Sciences [physics]/Signal and Image processing01 natural sciencesNon-negative Matrix FactorizationNon-negative matrix factorizationMatrix decomposition010309 opticsSpectral reconstructionOpticsDermis[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing0103 physical sciences0202 electrical engineering electronic engineering information engineeringmedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingChromophores quantificationOptical reflectance[ INFO.INFO-IM ] Computer Science [cs]/Medical Imagingintegumentary systembusiness.industrymedicine.diseasemedicine.anatomical_structureSignal Processing020201 artificial intelligence & image processingEpidermisSkin optical reflectance mapsbusinessBiological system[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing
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Optimal maps and exponentiation on finite dimensional spaces with Ricci curvature bounded from below

2013

We prove existence and uniqueness of optimal maps on $RCD^*(K,N)$ spaces under the assumption that the starting measure is absolutely continuous. We also discuss how this result naturally leads to the notion of exponentiation.

Mathematics - Differential GeometryExponentiationLower Ricci bounds; Optimal maps; Optimal transport; RCD spaces01 natural sciencesMeasure (mathematics)Combinatoricssymbols.namesakeMathematics - Metric GeometryRCD spacesSettore MAT/05 - Analisi MatematicaFOS: MathematicsOptimal transportMathematics::Metric GeometryUniqueness0101 mathematicsLower Ricci bounds[MATH.MATH-MG]Mathematics [math]/Metric Geometry [math.MG]Ricci curvatureMathematicsDiscrete mathematics010102 general mathematicsMetric Geometry (math.MG)Absolute continuity16. Peace & justice010101 applied mathematicsMathematics::LogicDifferential geometryDifferential Geometry (math.DG)Fourier analysisBounded functionsymbolsOptimal mapsGeometry and Topology
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Polynomial and horizontally polynomial functions on Lie groups

2022

We generalize both the notion of polynomial functions on Lie groups and the notion of horizontally affine maps on Carnot groups. We fix a subset $S$ of the algebra $\mathfrak g$ of left-invariant vector fields on a Lie group $\mathbb G$ and we assume that $S$ Lie generates $\mathfrak g$. We say that a function $f:\mathbb G\to \mathbb R$ (or more generally a distribution on $\mathbb G$) is $S$-polynomial if for all $X\in S$ there exists $k\in \mathbb N$ such that the iterated derivative $X^k f$ is zero in the sense of distributions. First, we show that all $S$-polynomial functions (as well as distributions) are represented by analytic functions and, if the exponent $k$ in the previous defini…

Mathematics - Differential GeometryLeibman Polynomialnilpotent Lie groupsApplied Mathematicspolynomithorizontally affine functionsryhmäteoriaMetric Geometry (math.MG)polynomial mapsGroup Theory (math.GR)harmoninen analyysiFunctional Analysis (math.FA)Mathematics - Functional AnalysisdifferentiaaligeometriaMathematics - Metric GeometryDifferential Geometry (math.DG)precisely monotone setsFOS: Mathematicspolynomial on groupsMathematics - Group TheoryAnnali di Matematica Pura ed Applicata (1923 -)
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Invariant Jordan curves of Sierpinski carpet rational maps

2015

In this paper, we prove that if $R\colon\widehat{\mathbb{C}}\to\widehat{\mathbb{C}}$ is a postcritically finite rational map with Julia set homeomorphic to the Sierpi\'nski carpet, then there is an integer $n_0$, such that, for any $n\ge n_0$, there exists an $R^n$-invariant Jordan curve $\Gamma$ containing the postcritical set of $R$.

Mathematics::Dynamical SystemsGeneral Mathematics[MATH.MATH-DS]Mathematics [math]/Dynamical Systems [math.DS]rational functionsMathematics::General TopologyDynamical Systems (math.DS)01 natural sciences37F10Combinatoricsexpanding Thusrston mapssymbols.namesakeHigh Energy Physics::TheoryMathematics::Quantum AlgebraFOS: MathematicsMathematics::Metric GeometryMathematics - Dynamical Systems0101 mathematicsInvariant (mathematics)MathematicsmatematiikkamathematicsSierpinski carpet Julia setsApplied Mathematicsta111010102 general mathematicsinvariant Jordan curveJulia setJordan curve theoremrationaalifunktiot010101 applied mathematicsrational mapsSierpinski carpetsymbols
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METRIC DIFFERENTIABILITY OF LIPSCHITZ MAPS

2013

AbstractAn extension of Rademacher’s theorem is proved for Lipschitz mappings between Banach spaces without the Radon–Nikodým property.

Mathematics::Functional AnalysisPure mathematicsGeneral MathematicsBanach spaceLipschitz continuityRadon-Nikodym PropertyLipschitz domainSettore MAT/05 - Analisi MatematicaLipschitz mapsMetric (mathematics)Metric mapMetric Diff erentiability.Differentiable functionMetric differentialSemi-differentiabilityMathematicsJournal of the Australian Mathematical Society
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