Search results for " Methods"
showing 10 items of 4102 documents
In Vivo Reprogramming for Brain and Spinal Cord Repair.
2015
AbstractCell reprogramming technologies have enabled the generation of various specific cell types including neurons from readily accessible patient cells, such as skin fibroblasts, providing an intriguing novel cell source for autologous cell transplantation. However, cell transplantation faces several difficult hurdles such as cell production and purification, long-term survival, and functional integration after transplantation. Recently,in vivoreprogramming, which makes use of endogenous cells for regeneration purpose, emerged as a new approach to circumvent cell transplantation. There has been evidence forin vivoreprogramming in the mouse pancreas, heart, and brain and spinal cord with …
"Table 3" of "Measurements of the charge asymmetry in top-quark pair production in the dilepton final state at $\sqrt{s}=8$ TeV with the ATLAS detect…
2017
The leptonic inclusive asymmetry in the fiducial volume.
Combined Innovation Policy: Linking Scientific and Practical Knowledge in Innovation Systems
2012
New research indicates that firms combining the science-based STI (Science, Technology, Innovation) and the experience-based DUI (Doing, Using, Interacting) modes of innovation are more efficient when it comes to improving innovation capacity and competitiveness. With regard to innovation policy, the STI mode calls for a supply driven policy, typically aimed to commercialise research results. The DUI mode suggests a demand driven policy approach, such as supporting the development of new products or services to specific markets. This paper analyses how the two types of innovation policy and the two innovation modes can be combined in regional innovation systems. The analysis builds on studi…
Formulations and exact algorithms for the distance-constrained generalized directed rural postman problem
2017
[EN] The generalized directed rural postman problem is an arc routing problem with many interesting real-life applications, such as routing for meter reading. In this application, a vehicle with a receiver travels through a series of neighborhoods. If the vehicle gets closer than a certain distance to a meter, the receiver is able to record the gas, water, or electricity consumption. Therefore, the vehicle does not need to traverse every street, but only a few, to get close enough to each meter. We study an extension of this problem in which a fleet of vehicles is available. Given the characteristics of the mentioned application, the vehicles have no capacities but there is a maximum distan…
Servicios de intermediación en línea en Europa : diseño de un sistema específico de solución de controversias
2021
Este trabajo analiza el sistema de solución de controversias específicamente diseñado, con la introducción de alternativas a la jurisdicción, en el Reglamento (UE) 2019/1150 sobre el fomento de la equidad y la transparencia para los usuarios profesionales de servicios de intermediación en línea, que ha entrado recientemente en vigor.
Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycl…
2009
Background The prevalence of and risk factors for central nervous system recurrence in patients with acute promyelocytic leukemia are not well established and remain a controversial matter. Design and Methods Between 1996 and 2005, 739 patients with newly diagnosed acute promyelocytic leukemia enrolled in two consecutive trials (PETHEMA LPA96 and LPA99) received induction therapy-with all-trans retinoic acid and idarubicin. Consolidation therapy comprised three courses of anthracycline monochemotherapy (LPA96), with all-trans retinoic acid and reinforced doses of idarubicin in patients with an intermediate or high risk of relapse (LPA99). Central nervous system prophylaxis was not given. Re…
Patients' and physicians' preferences for type 2 diabetes mellitus treatments in Spain and Portugal: a discrete choice experiment.
2015
Objective: To assess Spanish and Portuguese patients' and physicians' preferences regarding type 2 diabetes mellitus (T2DM) treatments and the monthly willingness to pay (WTP) to gain benefits or avoid side effects. Methods: An observational, multicenter, exploratory study focused on routine clinical practice in Spain and Portugal. Physicians were recruited from multiple hospitals and outpatient clinics, while patients were recruited from eleven centers operating in the public health care system in different autonomous communities in Spain and Portugal. Preferences were measured via a discrete choice experiment by rating multiple T2DM medication attributes. Data were analyzed using the cond…
Calibration of the photon spectrometer PHOS of the ALICE experiment
2019
Journal of Instrumentation 14(05), P05025 - P05025 (2019). doi:10.1088/1748-0221/14/05/P05025
Visibilidad internacional de la investigación de la Universitat de València (Web of Science 2000-2009)
2013
En esta publicación se ofrecen los primeros resultados del análisis de la producción científica de la Universitat de València para la década 2000-2009 realizado mediante la explotación de las bases de datos de la Web of Science (SCI, SSCI y A&HCI). La información está organizada en dos capítulos. El primero, dedicado a ofrecer una imagen general de la producción de la Universitat, permite apreciar el volumen de publicaciones circulantes en esas bases de datos, su crecimiento en el periodo estudiado, la tipología documental, el idioma de publicación y su clasificación temática. Para esto se han utilizado dos clasificaciones, la primera más detallada basada en las 247 categorías temáticas en …