Search results for " Methods"

showing 10 items of 4102 documents

SMART: Unique splitting-while-merging framework for gene clustering

2014

© 2014 Fa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Successful clustering algorithms are highly dependent on parameter settings. The clustering performance degrades significantly unless parameters are properly set, and yet, it is difficult to set these parameters a priori. To address this issue, in this paper, we propose a unique splitting-while-merging clustering framework, named "splitting merging awareness tactics" (SMART), which does not require any a priori knowledge of either the number …

Clustering algorithmsMicroarrayslcsh:MedicineGene ExpressionBioinformaticscomputer.software_genreCell SignalingData MiningCluster Analysislcsh:ScienceFinite mixture modelOligonucleotide Array Sequence AnalysisPhysicsMultidisciplinarySMART frameworkConstrained clusteringCompetitive learning modelBioassays and Physiological AnalysisMultigene FamilyCanopy clustering algorithmEngineering and TechnologyData miningInformation TechnologyGenomic Signal ProcessingAlgorithmsResearch ArticleSignal TransductionComputer and Information SciencesFuzzy clusteringCorrelation clusteringResearch and Analysis MethodsClusteringMolecular GeneticsCURE data clustering algorithmGeneticsGene RegulationCluster analysista113Gene Expression Profilinglcsh:RBiology and Life SciencesComputational BiologyCell BiologyDetermining the number of clusters in a data setComputingMethodologies_PATTERNRECOGNITIONSplitting-merging awareness tactics (SMART)Signal ProcessingAffinity propagationlcsh:QGene expressionClustering frameworkcomputer
researchProduct

Co-simulation and Formal Verification of Co-operative Drone Control With Logic-Based Specifications

2021

Abstract Unmanned aerial vehicle (UAV) co-operative systems are complex cyber-physical systems that integrate a high-level control algorithm with pre-existing closed implementations of lower-level vehicle kinematics. In model-driven development, simulation is one of the techniques that are usually applied, together with testing, in the analysis of system behaviours. This work proposes a method and tools to validate the design of UAV co-operative systems based on co-simulation and formal verification. The method uses the Prototype Verification System, an interactive theorem prover based on a higher-order logic language, and the Functional Mock-up Interface, a widely accepted standard for co-…

Co operativeformal methodsGeneral Computer Sciencetheorem proverComputer scienceControl (management)formal methods co-operative control co-simulation verification theorem proverCo-simulationDroneco-operative controlSettore ING-INF/04 - Automaticaformal methodco-simulationverificationFormal verificationSimulation
researchProduct

Combined approaches to identify genomic regions involved in phenotypic differentiation between low divergent breeds: Application in Sardinian sheep p…

2019

Selective breeding has led to modifications in the genome of many livestock breeds. In this study, we identified the genomic regions that may explain some of the phenotypic differences between two closely related breeds from Sardinia. A total of 44 animals, 20 Sardinian Ancestral Black (SAB) and 24 Sardinian White (SW), were genotyped using the Illumina Ovine 50K array. A total of 68, 38 and 15 significant markers were identified using the case–control genome-wide association study (GWAS), the Bayesian population differentiation analysis (FST) and the Rsb metric, respectively. Comparisons among the approaches revealed a total of 22 overlapping markers between GWAS and FST and one marker bet…

CoatGenotypePopulationGenome-wide association studygenome-wide methodsBiologySelective breedingGenomePolymorphism Single NucleotideSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoFood Animalsgenome-wide methods; genomic regions; Ovine BeadChip50K; Sardinian sheep breedsSardinian sheep breedsAnimalsGenetic variabilitygenomic regionseducationGeneOvine BeadChip50Keducation.field_of_studySheepHomozygoteMolecular Sequence AnnotationGeneral MedicineGenomicsgenome-wide methodgenomic regionWhite (mutation)PhenotypeEvolutionary biologyAnimal Science and ZoologyJournal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und ZuchtungsbiologieREFERENCES
researchProduct

Applying the Techniques on Materials I

2012

The knowledge of the composition of the natural dye mixtures gives hints on appropriate procedures for restoration strategies. Identification of the dyes used, the establishment of their biological source, how they have been prepared, how these historical textiles were made, can provide important information. The dyestuffs used up to nineteenth century were either of plant (weld, madder, indigo, etc.) or animal origin (cochineal, shellfish, etc.) and belonged to various chemical types, such as flavonoids (yellow), anthraquinones (red) and indigoids (blue and violet). In this study microsamples (19) were examined from 11 Mevlana’s kaftans, dervishs’ dresses and dated from the thirteenth cent…

CochinealChromatographybiologyChemistryExtraction methodsbiology.organism_classificationAnimal originNatural dyeIndigo
researchProduct

Reflections on Connectionist Modeling

2018

International audience

Cognition[SCCO.PSYC] Cognitive science/PsychologyPsychology Research Methods and Statistics[SCCO.PSYC]Cognitive science/PsychologyPsychology[ SCCO.PSYC ] Cognitive science/PsychologyComputingMilieux_MISCELLANEOUS
researchProduct

The Psychology of Thinking in Creating AI

2021

The broad-scale emergence of AI in industry calls forth basic questions in terms of the knowledge bases and approaches relevant for its design. Engineering design has been mainly developed for electromechanical artifacts. In practice, this has meant that the scientific knowledge required for creating technical artifacts such as engines, cars, ships, cranes, telephones, radios, TVs, and simple data processing units has been natural science. However, one cannot find intelligent processes by means of physics and chemistry. Natural scientific phenomena follow their deterministic laws, but intelligence is based on selection and decision processes. The conceptual landscape of natural science is o…

Cognitive modelPhysicsSociology of scientific knowledge/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyOperationalizationGRASPInformation processingPsychology of ThinkingData scienceEngineering DesignKnowledge-based systemsAIArtificial IntelligenceComputer ScienceDesign MethodsSDG 7 - Affordable and Clean EnergyPsychologyEngineering design processDesign technologyCognitive Models
researchProduct

Teaching types with a cognitively effective worked example format

2015

AbstractTeaching functional programming as a second programming paradigm is often difficult as students can have strong preconceptions about programming. When most of these preconceived ideas fail to be confirmed, functional programming may be seen as an unnecessarily difficult topic. A typical topic that causes such difficulties is the language of types employed by many modern functional languages. In this paper, we focus on addressing this difficulty through the use of step-by-step calculations of type expressions. The outcome of the study is an elaboration of a worked example format and a methodical approach for teaching types to beginner functional programmers.

Cognitive scienceta113Functional programmingFocus (computing)Computer scienceteaching methodsProgramming paradigmfunctional programmingOutcome (game theory)SoftwareElaborationJournal of Functional Programming
researchProduct

Effect of inter-crystal scatter on estimation methods for random coincidences and subsequent correction.

2008

Random coincidences can contribute substantially to the background in positron emission tomography (PET). Several estimation methods are being used for correcting them. The goal of this study was to investigate the validity of techniques for random coincidence estimation, with various low-energy thresholds (LETs). Simulated singles list-mode data of the MADPET-II small animal PET scanner were used as input. The simulations have been performed using the GATE simulation toolkit. Several sources with different geometries have been employed. We evaluated the number of random events using three methods: delayed window (DW), singles rate (SR) and time histogram fitting (TH). Since the GATE simula…

CoincidenceCrystalRandom AllocationImaging Three-DimensionalHOT RegionHistogramSmall animalStatisticsImage Processing Computer-AssistedAnimalsScattering RadiationRadiology Nuclear Medicine and imagingMathematicsTomography Emission-Computed Single-PhotonModels StatisticalRadiological and Ultrasound TechnologyComputersCompton scatteringReproducibility of ResultsReconstruction algorithmEquipment DesignModels TheoreticalComputational physicsPositron-Emission TomographyEstimation methodsCrystallizationMonte Carlo MethodSoftwarePhysics in medicine and biology
researchProduct

A Generalised RBF Finite Difference Approach to Solve Nonlinear Heat Conduction Problems on Unstructured Datasets

2011

Radial Basis Functions have traditionally been used to provide a continuous interpolation of scattered data sets. However, this interpolation also allows for the reconstruction of partial derivatives throughout the solution field, which can then be used to drive the solution of a partial differential equation. Since the interpolation takes place on a scattered dataset with no local connectivity, the solution is essentially meshless. RBF-based methods have been successfully used to solve a wide variety of PDEs in this fashion. Such full-domain RBF methods are highly flexible and can exhibit spectral convergence rates Madych & Nelson (1990). However, in their traditional implementation the fu…

CollocationPartial differential equationMeshless freezing nonlinear heat conduction phase change radial basis functionLinear systemMathematical analysisFinite differenceApplied mathematicsBasis functionDomain decomposition methodsRadial basis functionInterpolationMathematics
researchProduct

Probing dynamics of dense suspensions: three-dimensional cross-correlation technique

1997

We describe the realization of a novel three-dimensional (3D) cross-correlation scheme, which provides the possibility to measure dynamic structure factors of highly concentrated colloidal samples without contributions of multiply scattered light. The apparatus is easier to align and more compact than the two-colour cross-correlation apparatus, which is commercially available. This should make the 3D cross-correlation set-up more convenient for routine applications, for example in industrial laboratories. We describe the set-up and discuss some special features of the optical components.

Colloid and Surface ChemistryOpticsInvestigation methodsCross-correlationbusiness.industryChemistryMeasure (physics)Scattered lightbusinessBiological systemRealization (systems)Light scatteringColloids and Surfaces A: Physicochemical and Engineering Aspects
researchProduct