Search results for " Middle"

showing 10 items of 1097 documents

Real-world evidence from a European cohort study of patients with treatment resistant depression : Baseline patient characteristics

2021

Journal of affective disorders 283, 115-122 (2021). doi:10.1016/j.jad.2020.11.124

AdultMaleDisease burden; Health-related quality of life; Major depressive disorder; Observational study; Patient-reported outcomes; Socio-economic status; Adult; Cohort Studies; Europe; Female; Humans; Male; Middle Aged; Quality of Life; Depressive Disorder Major; Depressive Disorder Treatment-Resistantmedicine.medical_specialtyHealth-related quality of lifeSocio-economic statusMajor depressive disorderCohort Studies03 medical and health sciencesDepressive Disorder Treatment-Resistant0302 clinical medicineQuality of lifeObservational studyInternal medicinemedicineHumansMedical historyDepression (differential diagnoses)Disease burdenDepressive DisorderDepressive Disorder MajorPatient-reported outcomesDisease burden Health-related quality of life Major depressive disorder Observational study Patient-reported outcomes Socio-economic statusbusiness.industryTreatment-ResistantMajorDisease burdenMiddle Agedmedicine.disease030227 psychiatry3. Good healthEuropePsychiatry and Mental healthClinical PsychologyPresenteeismQuality of LifeMajor depressive disorderFemalebusinessTreatment-resistant depression030217 neurology & neurosurgeryCohort study
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Recollection and familiarity in hippocampal amnesia

2008

Currently, there is a general agreement that two distinct cognitive operations, recollection and familiarity, contribute to performance on recognition memory tests. However, there is a controversy about whether recollection and familiarity reflect different memory processes, mediated by distinct neural substrates (dual-process models), or whether they are the expression of memory traces of different strength in the context of a unitary declarative memory system (unitary-strength models). Critical in this debate is the status of recognition memory in hippocampal amnesia and, in particular, whether the various structures in the medial temporal lobe (MTL) contribute differentially to the recol…

AdultMaleDissociation (neuropsychology)Cognitive NeuroscienceAmnesiaHippocampal formationRecognition (Psychology)Pattern RecognitionRecognition (Psychology); Hippocampus; Pattern Recognition Visual; Humans; Brain Damage Chronic; Adult; Middle Aged; Mental Recall; Male; AmnesiaHippocampusTemporal lobePerirhinal cortexmedicineHumansBrain DamageChronicRecognition memoryRecallCognitionRecognition PsychologyMiddle Agedamnesia recognition memory recollection familiarity hippocampusmedicine.anatomical_structurePattern Recognition VisualMental RecallBrain Damage ChronicSettore MED/26 - NeurologiaAmnesiamedicine.symptomPsychologyVisualCognitive psychology
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Localization of Congenital Tegmen Tympani Defects

2007

Objective: This study sets out to demonstrate the normal developmental steps of the tegmen tympani and thus explains the typical localization of congenital tegmental defects. Specimens: For this study, 79 macerated and formalin-fixed human temporal bones from 14th fetal week to adults were observed and prepared. Intervention: Macroscopic and microscopic examination of the prenatal and postnatal changes of the tegmen tympani during its development. Main Outcome Measure: Temporal bones from 14th fetal week to adults underwent descriptive anatomic studies to understand the normal development of the tegmen tympani and to find a possible cause of its congenital defects. Results: The medial part …

AdultMaleEar MiddleDehiscencestomatognathic systemOsteogenesisPregnancyTemporal bonemedicineHumansInner earProcess (anatomy)Tympanic Membrane PerforationOssificationbusiness.industryInfant NewbornInfantTemporal BoneAnatomyGeniculate GanglionSensory Systemsmedicine.anatomical_structureOtorhinolaryngologyChild PreschoolIntramembranous ossificationMiddle earFemalesense organsNeurology (clinical)Geniculate ganglionmedicine.symptombusinessOtology & Neurotology
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Anxiety symptoms among informal caregivers in 47 low- and middle-income countries: A cross-sectional analysis of community-based surveys.

2022

Background-\ud \ud There are no multi-country studies on the association between informal caregiving and anxiety from low- and middle-income countries (LMICs). Therefore, we investigated this relationship in a large predominantly nationally representative sample from 47 LMICs.\ud \ud Methods-\ud \ud Cross sectional data from the World Health Survey were analyzed. Anxiety symptoms referred to severe or extreme problems with worries or anxiety in the past 30 days.\ud \ud Information on caregiving in the past 12 months was obtained. Multivariable logistic regression analysis adjusting for age, sex, marital status, education, household size, employment, disability, and country was conducted. Da…

AdultMaleGerontologymedicine.medical_specialtyAdolescentCross-sectional studyEpidemiologyPsychological interventionAnxietyLogistic regressionCare provisiona cross-sectional analysis of community-based surveys.- Journal of affective disorders 2021 [Smith L. Shin J. I. Oh H. López Sánchez G. F. Underwood B. Jacob L. Veronese N. Soysal P. Butler L. Barnett Y. et al. -Anxiety symptoms among informal caregivers in 47 low- and middle-income countries]EpidemiologymedicineHumansDeveloping CountriesPovertyAnxiety Caregivers Low- and middle-income countries EpidemiologyLow- and middle-income countriesbusiness.industryMental healthPsychiatry and Mental healthClinical PsychologyCross-Sectional StudiesCaregiversAnxietyMarital statusFemalemedicine.symptombusiness
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HBV DNA suppression and HBsAg clearance in HBeAg negative chronic hepatitis B patients on lamivudine therapy for over 5 years

2012

Background & Aims In long-term responder patients, it is unclear whether lamivudine (LAM) monotherapy should be continued or switched to a high-genetic-barrier analogue. This study aims at assessing LAM efficacy over a 5-year period and the residual risk of drug resistance. The rate of HBsAg clearance and LAM long-term safety profile were also evaluated. Methods One hundred and ninety-one patients with chronic HBeAg-negative hepatitis B successfully treated with LAM monotherapy for at least 5years were included. Biochemical and virological tests were assessed every 3months in all patients and HBsAg quantification was performed in 45/191. Reverse-transcriptase (RT) region was directly sequen…

AdultMaleHBsAgmedicine.medical_specialtyChronic hepatitis B; Lamivudine; Nucleos(t)ide analogues; Viral resistance; Adult; Aged; Antiviral Agents; DNA Viral; Female; Hepatitis B Surface Antigens; Hepatitis B e Antigens; Hepatitis B Chronic; Humans; Lamivudine; Male; Middle Aged; Real-Time Polymerase Chain Reaction; Time Factors; HepatologyTime FactorsCirrhosisDrug resistanceReal-Time Polymerase Chain Reactionmedicine.disease_causeChronic hepatitis BAntiviral AgentsGastroenterologyHepatitis B ChronicInternal medicineHBVmedicineHumansViralHepatitis B e AntigensChronicAgedHepatitis B virusHepatitis B Surface AntigensHepatologybusiness.industryViral resistanceLamivudineDNAMiddle AgedHepatitis BHepatitis Bmedicine.diseaseNucleos(t)ide analoguesResidual riskHBeAgLamivudineDNA ViralImmunologyFemalebusinessmedicine.drug
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Frequency and correlates of anxiety symptoms during the COVID-19 pandemic in low- and middle-income countries: A multinational study

2021

Objective Studies have documented the significant direct and indirect psychological, social, and economic consequences of the Coronavirus disease 2019 (COVID-19) in many countries but little is known on its impact in low- and middle-income countries (LMICs) already facing difficult living conditions and having vulnerable health systems that create anxiety in individuals for themselves and their loved ones. Using a multinational convenience sample from four LMICs (DR Congo, Haiti, Rwanda, and Togo), this study aims to explore the prevalence of anxiety symptoms and associated risk and protective factors during the COVID-19 pandemic. Methods A total of 1222 individuals (40.9% of women) complet…

AdultMaleHealth Knowledge Attitudes PracticeSocial stigmamedia_common.quotation_subjectShort CommunicationSocial StigmaDeveloping countryAnxietyStigmatizationExposure03 medical and health sciences0302 clinical medicineRisk FactorsEnvironmental healthPandemicPrevalencemedicineHumansDeveloping CountriesBiological PsychiatryLow- and Middle-Income Countriesmedia_commonCommunity resilienceResiliencebusiness.industryRwanda1. No povertyCOVID-19Middle AgedProtective FactorsResilience PsychologicalMental healthHaiti3. Good health030227 psychiatryPsychiatry and Mental healthCongoTogoAnxietyFemaleHealth educationPsychological resiliencemedicine.symptombusiness030217 neurology & neurosurgeryJournal of Psychiatric Research
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The impact of pictorial health warnings on tobacco products in smokers behaviours and knowledge: The first quasi-experimental field trial after the i…

2019

Background. The aim of the study was to evaluate in the Italian smokers, the effects of implementation of the law about Pictorial Health Warnings (PHWs) on tobacco products.Methods. A quasi-experimental longitudinal design was conducted between 2016 and 2017. The data were collected before (pre-PHW/Wave 1) and after (post-PHW/Wave 2) the implementation of the law. The adopted questionnaire included impact of advertisement (Label Impact Index, LII), quitting behavior and knowledge of tobacco related diseases.Results. 455 respondents completed both the Waves. 7.7% of smokers declared to have stopped smoking in Wave 2 and 29% of these declared the PHWs as one of the reasons to quit. The knowle…

AdultMaleHealth Knowledge Attitudes Practicehealth warningQuasi-experimental studyProduct LabelingPictorial warningsPictorial Works as TopicYoung AdultPictorial warningAdvertisingSurveys and QuestionnairesHealth labelHumansLongitudinal StudiesHealth labelsHealth warningsPracticeMotivationpictorial warnings health labels health warnings tobacco advertisement quasi-experimental studyHealth KnowledgeTobacco advertisementTobacco ProductsTobacco Use DisorderMiddle AgedItalyAttitudesFemaleSmoking CessationHealth labels; Health warnings; Pictorial warnings; Quasi-experimental study; Tobacco advertisementpictorial warnings; health labels; health warnings; tobacco advertisement; quasi-experimental studyHealth labels; Health warnings; Pictorial warnings; Quasi-experimental study; Tobacco advertisement; Adult; Advertising; Female; Health Knowledge Attitudes Practice; Humans; Italy; Longitudinal Studies; Male; Middle Aged; Motivation; Pictorial Works as Topic; Smoking Cessation; Surveys and Questionnaires; Tobacco Products; Tobacco Use Disorder; Young Adult; Product Labeling
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Italian Health Care Workers’ Knowledge, Attitudes, and Practices Regarding Human Papillomavirus Infection and Prevention

2020

Objective: To assess healthcare workers&rsquo

AdultMaleHealth Knowledge Attitudes Practicemedicine.medical_specialtyHPVknowledgegenetic structuresHealth PersonnelHealth Toxicology and MutagenesisUterine Cervical Neoplasmslcsh:MedicineScientific literatureimmunizationSettore MED/42 - Igiene Generale E ApplicataArticle03 medical and health sciences0302 clinical medicinepreventionAttitude Awareness Healthcare workers HPV Immunization Knowledge Practice Prevention Sexually transmitted infection Adult Cross-Sectional Studies Female Italy Middle Aged Papillomavirus Vaccines Papillomavirus Infections Uterine Cervical NeoplasmsSurveys and QuestionnairesvaccineIntervention (counseling)Health caremedicineHumansAttitude; Awareness; Healthcare workers; HPV; Immunization; Knowledge; Practice; Prevention; Sexually transmitted infection; VaccineawarenessPapillomavirus Vaccinessexually transmitted infection030212 general & internal medicineHuman papillomavirusbusiness.industryhealthcare workersPapillomavirus Infectionslcsh:RPublic Health Environmental and Occupational HealthMiddle AgedProduct characteristicspracticeCross-Sectional StudiesItaly030220 oncology & carcinogenesisFamily medicineattitudeMulticenter surveyPropensity score matchingFemalebusinessInternational Journal of Environmental Research and Public Health
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Rare NLRP12 variants associated with the NLRP12-autoinflammatory disorder phenotype: an Italian case series.

2013

AdultMaleHeredityAdolescentIntracellular Signaling Peptides and Proteinsautoinflammatory disorder phenotype NLRP12TRAPSMiddle AgedCryopyrin-Associated Periodic SyndromesPedigreePhenotypeTreatment OutcomeSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAItalyMutationHumansFemaleGenetic Predisposition to DiseaseAdolescent; Adult; Child Preschool; Cryopyrin-Associated Periodic Syndromes; Female; Genetic Predisposition to Disease; Heredity; Humans; Immunosuppressive Agents; Intracellular Signaling Peptides and Proteins; Italy; Male; Middle Aged; Pedigree; Phenotype; Treatment Outcome; MutationChildPreschoolImmunosuppressive Agents
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The epidemiology of Varicella Zoster Virus infection in Italy

2008

Abstract Background The epidemiological importance of varicella and zoster and the availability of an efficacious and safe vaccine have led to an important international debate regarding the suitability of mass vaccination. The objective of the study was to describe the epidemiology of varicella and zoster in Italy and to determine whether there have been changes with respect to observations provided by an analogous study conducted 8 years ago, in order to define the most appropriate vaccination strategy. Methods A number of data sources were evaluated, a cross-sectional population-based seroprevalence study was conducted on samples collected in 2004, and the results were compared with data…

AdultMaleHerpesvirus 3 HumanSettore MED/07 - Microbiologia E Microbiologia ClinicaPediatricsmedicine.medical_specialtyAdolescentCross-sectional studyPopulationVaricellamedicine.disease_causeYoung AdultChickenpoxSeroepidemiologic StudiesEnvironmental healthEpidemiologymedicineHumansSeroprevalencePreschoolChildeducationVaricella Zosterepidemiology infection in Italyeducation.field_of_studyChickenpoxbusiness.industrylcsh:Public aspects of medicineHerpesvirus 3Infant NewbornPublic Health Environmental and Occupational HealthVaricella zoster virusInfantvirus diseaseslcsh:RA1-1270Middle AgedNewbornmedicine.diseaseVaccinationCross-Sectional StudiesItalyInfectious disease (medical specialty)Adolescent; Adult; Chickenpox; Child; Child Preschool; Cross-Sectional Studies; Female; Herpesvirus 3 Human; Humans; Infant; Infant Newborn; Italy; Male; Middle Aged; Seroepidemiologic Studies; Young AdultChild PreschoolFemalebusinessHumanResearch ArticleBMC Public Health
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