Search results for " Mimetics"
showing 7 items of 17 documents
Verbal, linguistique et langagier. Enunciazione e antropologia del gesto mentale.
2018
The paper aims to explain the metalinguistic value of three distinct but related concepts of the Theory of Predicative and Enunciative Operations (henceforth, TOPE). This research program, conceived by the french linguist Antoine Culioli, introduced a fundamental theoretical distinction between the concepts of “verbal” “linguistique” et “langagier”. The first concept refer to the complementary processes of phonation and audition that characterize every interlocutory exchange. The second one refer to the rules that characterize the formal system of a specific natural language. The third and last concept refer to the language operations viewed as processes of construction of meaning. With par…
Chemoenzymatic Synthesis of Functional Sialyl LewisX Mimetics with a Heteroaromatic Core
2014
Functional mimetics of the sialyl Lewis(X) tetrasaccharide were prepared by the enzymatic sialylation of a 1,3-diglycosylated indole and a glycosyl azide, which was subsequently transformed into a 1,4-diglycosylated 1,2,3-triazole, by using the trans-sialidase of Trypanosoma cruzi. These compounds inhibited the binding of E-, L-, and P-selectin-coated nanoparticles to polyacrylamide-bound sialyl-Lewis(X) -containing neighboring sulfated tyrosine residues (sTyr/sLe(X) -PAA) at low or sub-millimolar concentrations. Except for E-selectin, the mimetics showed higher activities than the natural tetrasaccharide.
Cognitive Mimetics for AI Ethics : Tacit Knowledge, Action Ontologies and Problem Restructuring
2020
Ethics and ethical information processing are an important problem for AI development. It is important for self-evident reasons, but also challenging in its’ implications and should be welcomed by designers and developers as an interesting technical challenge. This article explores AI ethics as a design problem and lays out how cognitive mimetics could be used a method for its design. AI ethics is conceptualized as a problem of implementation on the one hand, and as a problem of ethical contents on the other. From the viewpoint of human information processing, ethics becomes a special case of ethical information processing - one that has deep implications in terms of AI abilities and inform…
Affective Mimetics, Emotional Information Space, and Metaverse
2021
Current technology design pursues applying human-like features to AI technologies. These attempts have faced many challenges due to the essential complexities of the human mind. Cognitive mimetics is a design approach to mimic human information processes in designing intelligent technologies. The focus is on mimicking cognition, human knowledge structures, and represented mental information contents which addresses a fundamental issue in technology design. However, cognition is one aspect of information processing in the human mind. Affective information processing also plays an essential role in addressing the meaningfulness of cognitive processes. This paper discusses affective mimetics (…
Human Digital Twins in Acquiring Information About Human Mental Processes for Cognitive Mimetics
2022
Modern information technology makes it possible to redesign the ways people work. In the future, machines can carry out intelligence-requiring tasks, which previously were done by people. It is thus good to develop methodologies for designing intelligent systems. An example of such methods is cognitive mimetics, i.e. imitating human information processing. Today, machines cannot by themselves navigate in archipelagos. However, the fact that people can take care of ship steering and navigation means that there is an information process, which makes it possible to navigate ships. This information process takes place inside the minds of navigating people. If we are able to explicate the inform…
IAP proteins as targets for drug development in oncology.
2013
The inhibitors of apoptosis (IAPs) constitute a family of proteins involved in the regulation of various cellular processes, including cell death, immune and inflammatory responses, cell proliferation, cell differentiation, and cell motility. There is accumulating evidence supporting IAP-targeting in tumors: IAPs regulate various cellular processes that contribute to tumor development, such as cell death, cell proliferation, and cell migration; their expression is increased in a number of human tumor samples, and IAP overexpression has been correlated with tumor growth, and poor prognosis or low response to treatment; and IAP expression can be rapidly induced in response to chemotherapy or …
Cognitive Mimetics and Human Digital Twins : Towards Holistic AI Design
2023
AI is replacing and supporting people in many intelligence-requiring tasks. Therefore, it is essential to consider the conceptual grounds of designing future technical artefacts and technologies for practical use. We are developing two new practical design tools: cognitive mimetics and human digital twins for AI designers. Cognitive mimetics analyses human information processing to be mimicked by intelligent technologies. Human digital twins provide a tool for modelling what people do based on the results of cognitive mimetics. Together they provide a new way of designing intelligent technology in individual tasks and industrial contexts. nonPeerReviewed