Search results for " Models"
showing 10 items of 4240 documents
Latvijas alus iespēju analīze eksportam uz Latīņameriku
2022
Maģistra darba tēma ir “Analīze par Latvijas alus eksporta iespējām Latīņamerikā”. Darba autore ir Jarlotte Camila Quintero Martinez un darba vadītājs - Prof., Erika Sumilo. Maģistra darba mērķis ir noteikt, kurš modelis tiks izmantots starptautiskā tirgus atlasei, un veikt Latīņamerikas tirgus izpēti, lai noskaidrotu, kura šī reģiona valsts būtu piemērotākā Latvijas alus eksportam. Lai sasniegtu maģistra darba mērķi, tiek veikta Latīņamerikas valstu izpēte, īstenota teorētiskā materiāla analīze par starptautisko tirgus atlases modeļu raksturojumu, kā arī riska pārvaldības un eksporta barjerām, tā rezultātā nosakot valsti ar labāko vidi Latvijas alus eksportam. Maģistra darbs sastāv no piec…
New Business Models In-The-Making in Extant MNCs: Digital Transformation in a Telco
2017
In recent years, we can observe the emergence of firms, born both digital and global, that have disrupted existing industries. Deploying digital technologies, they have developed innovative value chains and business models that threaten established multinational companies (MNCs). In this chapter, we examine how MNCs can and do respond to the challenge digital technologies represent. We describe the main facets of digital technologies and discus the potential these have to undermine the value chains and business models of established MNCs. In order to illustrate this, we employ longitudinal data from Telenor, a leading multinational mobile telecom company. Telenor perceives digitalization as…
Effects of COVID-19 on Business Models in Romania and the Netherlands, A Digitalization Perspective
2020
Abstract The research objective is to study how Romanian and Dutch organizations’ business models have changed under COVID-19 conditions. The role of digitalization in adapting business models and business practices is studied. The theoretical background reviews literature about business models and their dimensions. Literature review investigated digitalization in Romanian and Dutch organizations. Research questions were: To what extent do Romanian and Dutch organizations use: • more digital methods in their offer to their clients now than before the crisis? • more digital methods in their business processes now than before the crisis? • more digital methods in communicating with their clie…
Dynamic business modeling for sustainability: Exploring a system dynamics perspective to develop sustainable business models
2019
In the last decade, business models for sustainability have gained increasing attraction by corporate sustainability scholars with international conferences and scientific journals encouraging the development of the debate on their design, use and innovation processes. Capitalizing on the basic principles, requirements, and methodological limitations found in the literature on sustainability‐oriented business model design, this paper aims to conceptualize a dynamic business modeling for sustainability approach, which combines an adapted sustainable business model canvas and system dynamics modeling. To this end, the paper also illustrates the key operating principles of the proposed approac…
Business continuity of business models : Evaluating the resilience of business models for contingencies
2019
Company business models are vulnerable to various contingencies in the business environment that may unexpectedly render their business logic ineffective. In particular, technological advancements, such as the Internet of things, big data, sharing economy and crowdsourcing, have enabled new forms of business models that can effectively and abruptly make traditional business models obsolete. By disrupting or even diminishing companies’ revenue streams, environmental contingencies may present a significant threat to business continuity (BC). Evaluating the resilience of business models against these contingencies should therefore be a core area of BC. However, existing BC approaches tend to f…
Estimation of Value-at-Risk on Romanian Stock Exchange Using Volatility Forecasting Models
2013
This paper aims to analyse the market risk (estimated by Value-at-Risk) on the Romanian capital market using modern econometric tools to estimate volatility, such as EWMA, GARCH models. In this respect, I want to identify the most appropriate volatility forecasting model to estimate the Value-at-Risk (VaR) of a portofolio of representative indices (BET, BET-FI and RASDAQ-C). VaR depends on the volatility, time horizon and confidence interval for the continuous returns under analysis. Volatility tends to happen in clusters. The assumption that volatility remains constant at all times can be fatal. It is determined that the most recent data have asserted more influence on future volatility th…
Exploiting Valve Timing for Pneumatic Energy Savings
2018
This research paper aims at addressing solutions that reduce air consumption in generic pneumatic systems used for pick-and-place operations. The investigation considers different system architectures both with a single control valve and two control valves arranged according to an independent metering configuration. Suitable control strategies are then proposed exploiting multiple timings to shut off the non-proportional switching valve(s). The resulting scenarios are experimentally evaluated on a dedicated test-bed. The main conclusion is that reduction of air consumption up to 73% is possible in comparison to the state-of-the-art layout for the reference application. Numerical simulations…
Ovine Carotid Artery-Derived Cells as an Optimized Supportive Cell Layer in 2-D Capillary Network Assays
2014
PLoS one 9(3), e91664 (2014). doi:10.1371/journal.pone.0091664
Molecular imaging of VEGF in gastrointestinal cancer in vivo using confocal laser endomicroscopy
2010
Vascular endothelial growth factor (VEGF) is a therapeutic target in gastrointestinal cancer (GiC). However, its in vivo visualisation could not be achieved to date with endoscopic techniques. Confocal laser endomicroscopy (CLE) is a novel imaging technique for gastrointestinal endoscopy providing in vivo microscopy at subcellular resolution. The aim of the study was to evaluate CLE for in vivo molecular imaging of VEGF in GiC.Molecular imaging of tumours in APCmin mice, in xenograft models and in surgical specimens of patients with colorectal cancer (CRC) was achieved after application of labelled antibodies. The tumour sites were scanned with the probe for the strongest specific fluoresce…
Microphthalmia, persistent hyperplastic hyaloid vasculature and lens anomalies following overexpression of VEGF-A188 from the αA-crystallin promoter
2007
Purpose During growth of the embryonic eye, dose- and site-specific expression of heparin-binding growth factors is critical for the formation of an appropriate vascular supply. Overexpression of vascular endothelial growth factor-A188 (VEGF-A188), a strongly heparin-binding, endothelial-specific mitogen, leads to severe disturbance of vascular and overall ocular morphology. This study aimed to evaluate the effects of VEGF-A188 overexpression on growth of ocular tissue components. Methods Stereological and immunohistochemical methods were employed to identify the vascular profiles, ocular tissue proportions, and cell types in VEGF-A188 transgenic mice and compare them with wild-type mice. R…