Search results for " Molecular structure"

showing 3 items of 23 documents

New 1,2,4-oxadiazole nortopsentin derivatives with cytotoxic activity

2019

New analogs of nortopsentin, a natural 2,4-bis(3&prime

anti-cancer agentCell SurvivalAnti-cancer agentsPharmaceutical ScienceAntineoplastic AgentsAntiproliferative activity01 natural sciencesArticlechemistry.chemical_compoundStructure-Activity RelationshipMarine alkaloidsSettore BIO/10 - BiochimicaDrug DiscoveryMoietyHumansPharmacology Toxicology and Pharmaceutics (miscellaneous)lcsh:QH301-705.5Cell ProliferationIndole testMolecular Structure010405 organic chemistryAcridine orangeImidazoles2 4-oxadiazole derivativesnortopsentin analogs2 4-oxadiazole derivatives; Anti-cancer agents; Antiproliferative activity; Marine alkaloids; Nortopsentin analogs 1; Antineoplastic Agents; Caco-2 Cells; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; HCT116 Cells; Humans; Imidazoles; MCF-7 Cells; Molecular Structure; Structure-Activity RelationshipPhosphatidylserineCell Cycle CheckpointsNortopsentin analogs 1HCT116 CellsSettore CHIM/08 - Chimica Farmaceutica0104 chemical sciences124-oxadiazole derivative010404 medicinal & biomolecular chemistrychemistryBiochemistry124-oxadiazole derivativeslcsh:Biology (General)ApoptosisCell cultureCancer cellMCF-7 CellsMarine alkaloid2 4-oxadiazole derivativeCaco-2 CellsEthidium bromide
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High temperature ferro-paraelectric phase transition in tris(trimethylammonium) nonachlorodiantimonate(III) (TMACA) studied by X-ray diffraction meth…

2000

Abstract The structure of [NH(CH3)3]3Sb2Cl9, tris(trimethylammonium) nonachlorodiantimonate(III) (TMACA) has been determined at 295 K and 373 K, below and above the high temperature ferro-paraelectric phase transition. In both phases the anionic sublattice of TMACA is built of characteristic two-dimensional (Sb2Cl93−)n polyanionic layers lying in the bc plane. In room temperature, ferroelectric phase (monoclinic, Pc space group) there are three crystallographically non-equivalent trimethylammonium [NH(CH3)3]+ cations. Two of them are located between polyanionic layers and the third one, disordered, inside the cavity formed by six SbCl63− octahedra. In the high temperature paraelectric phase…

ferro-paraelectric phase transitionTrisPhase transitionMaterials sciencedisorderGeneral ChemistryDielectricantimony(III)Ferroelectricitychemistry.chemical_compoundCrystallographychemistryOctahedronStructural BiologyLattice (order)Phase (matter)X-ray crystallographyMaterials Chemistrycrystal and molecular structurehalogenoantimonates(III)Monoclinic crystal systemActa Crystallographica Section A Foundations of Crystallography
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Johnson-Nyquist Noise Effects in Neutron Electric-Dipole-Moment Experiments

2021

Magnetic Johnson-Nyquist noise (JNN) originating from metal electrodes, used to create a static electric field in neutron electric-dipole-moment (nEDM) experiments, may limit the sensitivity of measurements. We present here the first dedicated study on JNN applied to a large-scale long-measurement-time experiment with the implementation of a co-magnetometry. In this study, we derive surface- and volume-averaged root-mean-square normal noise amplitudes at a certain frequency bandwidth for a cylindrical geometry. In addition, we model the source of noise as a finite number of current dipoles and demonstrate a method to simulate temporal and three-dimensional spatial dependencies of JNN. The c…

noiseNeutron electric dipole momentMagnetometerAtomic Physics (physics.atom-ph)FOS: Physical sciencesNeutron Physics[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]01 natural sciencesNoise (electronics)010305 fluids & plasmaslaw.inventionPhysics - Atomic PhysicslawElectric field0103 physical sciencesNeutronNuclear Experiment (nucl-ex)010306 general physicsNuclear ExperimentPhysicshigh-precision experimentsprecision measurementJohnson–Nyquist noiseAtomic and molecular structure and dynamics[PHYS.PHYS.PHYS-GEN-PH]Physics [physics]/Physics [physics]/General Physics [physics.gen-ph]Computational physicsDipoleNuclear Spin ResonanceAmplitudeElectromagnetic Field Calculations
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