Search results for " Mucosal"
showing 10 items of 72 documents
Endoscopic mucosal resection: an evolving therapeutic strategy for non-polypoid colorectal neoplasia
2004
Endoscopic management for laterally spreading tumours of the colorectum is a safe and effective treatment and may be an alternative to surgery in selected patients Colorectal cancer develops in approximately 5–6% of the adult population and is one of the leading causes of cancer death in Europe and the USA.1,2 Screening colonoscopy is the widely accepted gold standard for early diagnosis of colorectal cancer and should be offered to patients older than 50 years.3–5 However, colonoscopy is increasingly in competition with computed tomographic virtual endoscopy.6 Therefore, it is essential to understand whether total colonoscopy rather than virtual endoscopy enables the detection of all relev…
Histology of the Oral Mucosa in Patients With BRONJ at III Stage: A Microscopic Study Proves the Unsuitability of Local Mucosal Flaps.
2012
Background: Bisphosphonate Osteonecrosis of the Jaw (BRONJ) is a newly recognized condition reported in patients treated with aminobisphosphonates (BF). BRONJ is defined as the presence of exposed necrotic alveolar bone that does not resolve over a period of 8 weeks in a patient taking bisphosphonates who has not had radiotherapy to the jaw. Treatment protocols have been outlined, but trials and outcomes of treatment and long-term follow-up data are not yet available. In 2004 an expert panel outlined recommendations for the management of bisphosphonate-associated osteonecrosis of the jaws. Through the histological study of the oral mucosa over the bone necrosis and around the osteonecrosis …
T1078 The Validity of a Biomarker Method for Indirect Detection of Gastric Mucosal Atrophy Versus Standard Histopathology
2008
Background Atrophy of the stomach mucosa is considered to be premalignant lesion for gastric cancer development; easy identification of this condition from a blood-sample would allow identifying the group of individuals at increased risk for cancer development.
Minimal Lesions of the Small Intestinal Mucosa: More than Morphology
2020
Minimal lesions of the small bowel are mucosal changes characterized by an increased number of intraepithelial lymphocytes (with or without crypt hyperplasia) and normal villous architecture. Such changes are associated with a wide spectrum of conditions, ranging from food intolerances to infections, and from drugs to immune diseases, with different clinical profiles and manifestations, which complicates the formulation of a differential diagnosis. Patient history, symptom evaluation, and histopathology are the diagnostic features needed to establish a correct diagnosis. Physicians should assist pathologists in formulating a precise morphological evaluation by taking well-oriented small int…
Oral mucosal lesions and their association with tobacco use and qat chewing among Yemeni dental patients.
2014
Objectives: This study aimed to assess the prevalence of oral mucosal lesions (OMLs) in patients attending outpa - tient dental clinics in Sana`a university, Yemen, and to evaluate the association of such lesions with age, gender, and oral habits. Materials and Methods: This cross-sectional study included 409 subjects (272 males, 137 females, age: 15-86 years). Detailed clinical examination was performed in accordance with international criteria. Patient history in - cluded age, gender, education, denture wearing and risk habits (tobacco use and qat chewing). Data were analyzed using SPSS 19.00. Results: The prevalence of OMLs was 58.4% with a significant difference between men (63.6%) and …
Prevalence of oral mucosal lesions in a brazilian military police population.
2014
Background Data obtained from oral health surveys are very important for identifying disease-susceptible groups and for developing dental care and prevention programs. So, the purpose of the current article was to investigate the prevalence of oral mucosa lesions (OMLs) in a population of Brazilian police. Material and Methods Interviews and oral cavity examinations were performed on a sample of 395 police officers who were randomly selected by the calibrated researcher. The number of individuals was obtained by a sample calculation using the finite population correction. The diagnostic criteria were based on the WHO (1997) criteria and adapted to Brazilian surveys. Results In total, 8.61% …
The prevalence of oral mucosal lesions in the patients visiting a dental school in Northern India in relation to sex, site and distribution: A retros…
2011
Objective: To determine the distribution of oro-mucosal lesions in patients of Maharishi Markendeshwer College of Dental Sciences and Research, (MMCDSR), Mullana. Further to identify sex predilection and different sites which are more susceptible to different oro-mucosal lesions. Materials and methods: A hospital based retrospective study was carried out from 1st January 2007 till 31st December 2009 at (MMCDSR), Mullana. A total of 451 biopsy reports were studied. Distribution and prevalence of oro-mucosal lesions among the data were analyzed using SPSS software package version 13. Results: There was no mention of habits in the biopsy reports of 85.4 % (385 patients) of the subjects. Out of…
The impact of COVID-19 on access to dental care for people with disabilities:a global survey during the COVID-19 first wave lockdown
2021
Background It is unclear what immediate impact the COVID-19 pandemic has had on delivery of oral healthcare to people with disabilities worldwide. Aim: To report the international impact of COVID-19 lockdown on oral healthcare provision for people with disabilities before, during and after the first lockdown (March to July 2020). Material and Methods Cross-sectional online self-administered survey of dentists who treat people with disabilities completed 10th to 31st of July 2020. Responses allowed comparison from before, during and immediately after the first wave lockdowns of the COVID-19 pandemic. Data were analysed using McNemar’s test to compare reported practice before to during lockdo…
Cytokine components and mucosal immunity in the oviduct of Xenopus laevis (amphibia, pipidae)
2011
Abstract Most studies on the mucosal immunity in female reproductive tissues have been performed in mammals. In all species, apart from their reproductive strategies, immunity in the genital mucosa is required to defend the host against luminal pathogens. In this study we investigated the role of the innate immunity of the oviductal mucosa of Xenopus laevis , an amphibian characterized by external fertilization. In particular we examined the expression and localization of Interleukin-1β (IL1B), Macrophage migration inhibitory factor (MIF) and Interleukin-1 receptor type 1 (IL1R1) in different oviductal portions including an upper glandular region, an intermediate and a lower aglandular regi…
Evaluation of waterborne exposure to heavy metals in innate immune defences present on skin mucus of gilthead seabream (Sparus aurata)
2015
Aquatic animals are continuously exposed to chemical pollutants but the effects evoked in skin surfaces, which receive the most direct contact with them, are poorly investigated. Terminal carbohydrate composition and immunological components present in skin mucus of gilthead seabream (Sparus aurata L.) specimens exposed to waterborne sublethal dosages of heavy metals [arsenic (As2O3), cadmium (CdCl2) and mercury (CH3HgCl) at 5, 5 and 0.04 μM, respectively for 2, 10 and 30 days were analysed. Moreover, the presence of a fucose binding lectin (FBL) was evaluated by western blot and the protein profiles were by SDS-PAGE and HPLC. Results showed little effects of heavy metals in the presence of…