Search results for " NASH"
showing 8 items of 48 documents
New Optimization and Security Approaches to Enhance the Smart Grid Performance and Reliability
2016
International audience; Nowadays, the Smart Grid (SG) is becoming smarter thanks to the integration of different information and communication technologies to enhance the reliability and efficiency of the power grid. However, several issues should be met to ensure high SG performance. Among these issues, we cite the problem of electric vehicles (EVs) integration into the SG to avoid electricity intermittence due to the important load that EVs can create. Another issue is the SG communication network security that can be attempted by malicious intruders in order to create damages and make the power grid instable. In this context, we propose at a first level a Bayesian game-theory model that …
“‘Bosques distantes”: a matéria dos livros e a pastoral modernista“ (“‘Distant woods’: The matter of books and the modernist pastoral“)
2022
This paper is part of a broader project that aims to examine the importance of the materials used in the making of illustrated books from a medial and ecocritical perspective. I focus on a specific case study in which I explore the attitude to nature encapsulated in the use of and reference to wood in British interwar wood-engraved illustrated books. My departure point is the English artist Paul Nash’s Places (Heinemann, 1922), a short collection of prose poems and wood-engravings. An elegy produced at a time when Nash was trying to come to terms with the aftermath of the First World War, Places was published after he made the great war paintings depicting the human losses and the ecocide p…
Atezolizumab plus bevacizumab versus lenvatinib or sorafenib in non-viral unresectable hepatocellular carcinoma: an international propensity score ma…
2022
Background: A growing body of evidence suggests that non-viral hepatocellular carcinoma (HCC) might benefit less from immunotherapy. Materials and methods: We carried out a retrospective analysis of prospectively collected data from consecutive patients with non-viral advanced HCC, treated with atezolizumab plus bevacizumab, lenvatinib, or sorafenib, in 36 centers in 4 countries (Italy, Japan, Republic of Korea, and UK). The primary endpoint was overall survival (OS) with atezolizumab plus bevacizumab versus lenvatinib. Secondary endpoints were progression-free survival (PFS) with atezolizumab plus bevacizumab versus lenvatinib, and OS and PFS with atezolizumab plus bevacizumab versus soraf…
Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease.
2022
Background & Aims: Obesity-associated inflammation is a key player in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, the role of macrophage scavenger receptor 1 (MSR1, CD204) remains incompletely understood. Methods: A total of 170 NAFLD liver biopsies were processed for transcriptomic analysis and correlated with clinicopathological features. Msr1(-/-) and wild-type mice were subjected to a 16-week high-fat and high-cholesterol diet. Mice and ex vivo human liver slices were treated with a monoclonal antibody against MSR1. Genetic susceptibility was assessed using genome-wide association study data from 1,483 patients with NAFLD and 430,101 participants of the U…
Delegated agency in multiproduct oligopolies with indivisible goods
2010
This paper focuses on oligopolistic markets in which indivisible goods are sold by multiproduct firms to a continuum of homogeneous buyers, with measure normalized to one, who have preferences over bundles of products. Our analysis contributes to the literature on delegated agency games with direct externalities and complete information, extending the insights by Berheim and Whinston (1986, a , b) to markets with indivisibilities. By analyzing a kind of extended contract schedules - mixed bundling prices - that discriminate on exclusivity, the paper shows that efficient equilibria always exist in such settings. There may also exist inefficient equilibria in which the agent chooses a subopti…
On Capturing Oil Rents with a National Excise Tax Revisited
2004
In this paper the scope of Bergstrom’s (1982) results is studied. Moreover, his analysis is extended assuming that extraction cost is directly related to accumulated extractions. For the case of a competitive market it is found that the optimal policy is a constant tariff if extraction is costless. However, with depletion effects, the optimal tariff must ultimately be decreasing. For the case of a monopolistic market the results depend crucially on the kind of strategies the importing country governments can play and on whether the monopolist chooses the price or extraction rate. For a price-setting monopolist it is shown that the importing countries cannot use a tariff to capture monopoly …
A New Score Unveils a High Prevalence of Mild Cognitive Impairment in Patients with Nonalcoholic Fatty Liver Disease
2021
Patients with nonalcoholic fatty liver disease (NAFLD) may show mild cognitive impairment (MCI). The neurological functions affected remain unclear. The aims were to: (1) Characterize the neuropsychological alterations in NAFLD patients; (2) assess the prevalence of impairment of neurological functions evaluated; (3) develop a new score for sensitive and rapid MCI detection in NAFLD; (4) assess differences in MCI features between patients with nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH); and (5) compare neuropsychological alterations in NAFLD patients with cirrhotic patients with MCI. Fifty-nine NAFLD patients and 53 controls performed psychometric tests assessin…
Socially-aware Dynamic Computation Offloading Scheme for Fog Computing System with Energy Harvesting Devices
2018
Fog computing is considered as a promising technology to meet the ever-increasing computation requests from a wide variety of mobile applications. By offloading the computation-intensive requests to the fog node or the central cloud, the performance of the applications, such as energy consumption and delay, are able to be significantly enhanced. Meanwhile, utilizing the recent advances of social network and energy harvesting (EH) techniques, the system performance could be further improved. In this paper, we take the social relationships of the EH mobile devices (MDs) into the design of computational offloading scheme in fog computing. With the objective to minimize the social group executi…