Search results for " Neurologic"

Inclusive Design for Alzheimer’s Disease: Low-cost Treatments, Design and ICT

2019

Inability to acquire new memories, difficulty to remember recent events and to recognize objects, places and people, visual-spatial disorientation, these are some of the disorders with which who is affected by neurological diseases must learn to live with. In a continuously evolving society, where the decreasing birth rate and the drops in mortality are consistent, the job of Architecture is precisely to interpret the requirements and needs of people who have lost the canonical relationship with the world and give them the possibility to recover it or maintain it through communication channels that use their remaining ability to understand. The indoors and outdoors acquire a “prosthesis fun…

Multi-subject fMRI analysis via combined independent component analysis and shift-invariant canonical polyadic decomposition

2014

Canonical polyadic decomposition (CPD) may face a local optimal problem when analyzing multi-subject fMRI data with inter-subject variability. Beckmann and Smith proposed a tensor PICA approach that incorporated an independence constraint to the spatial modality by combining CPD with ICA, and alleviated the problem of inter-subject spatial map (SM) variability.This study extends tensor PICA to incorporate additional inter-subject time course (TC) variability and to connect CPD and ICA in a new way. Assuming multiple subjects share common TCs but with different time delays, we accommodate subject-dependent TC delays into the CP model based on the idea of shift-invariant CP (SCP). We use ICA …

The Tachykinin Neuroimmune Connection in Inflammatory Pain

1991

Modelling the insect Mushroom Bodies: Application to sequence learning

2015

Learning and reproducing temporal sequences is a fundamental ability used by living beings to adapt behaviour repertoire to environmental constraints. This paper is focused on the description of a model based on spiking neurons, able to learn and autonomously generate a sequence of events. The neural architecture is inspired by the insect Mushroom Bodies (MBs) that are a crucial centre for multimodal sensory integration and behaviour modulation. The sequence learning capability coexists, within the insect brain computational model, with all the other features already addressed like attention, expectation, learning classification and others. This is a clear example that a unique neural struc…

A Dichoptic Edge Effect Resulting from Binocular Contour Dominance

1980

If one eye sees a bright field on a dark surround while a homogeneous background is presented to the other eye, then a distinct dark zone appears at the outer borders of the field.If the surround is coloured, then the zone is of corresponding hue. The effect disappears if the edge of the field can be fused with a bar of appropriate contrast. The influence of parameters such as pattern contrast and size were studied quantitatively. A model is proposed relating the effect to receptive-field organisation and the fusion process.

Implementations of a novel algorithm for colour constancy

1997

AbstractIn agreement with the principles of the relativistic model proposed by Creutzfeldtet al., with the photometric rule (lightness anchoring rule) and with the influence of simultaneous contrast in the appearance of a visual scene, we propose a first-stage mechanism yielding substantial colour constancy. We have defined a set of first-stage colour descriptors, and to test their utility, we have performed a simulation using a Machine Vision System (MVS). The statistical stability of the descriptors for Munsell samples under different illuminants is good.

Reconciling time, space and function: a new dorsal-ventral stream model of sentence comprehension.

2013

We present a new dorsal–ventral stream framework for language comprehension which unifies basic neurobiological assumptions (Rauschecker & Scott, 2009) with a cross-linguistic neurocognitive sentence comprehension model (eADM; Bornkessel & Schlesewsky, 2006). The dissociation between (time-dependent)syntactic structure-building and (time-independent) sentence interpretation assumed within thee ADM provides a basis for the division of labour between the dorsal and ventral streams in comprehension.We posit that the ventral stream performs time-independent unifications of conceptual schemata,serving to create auditory objects of increasing complexity. The dorsal stream engages in the time-depe…

Temporally precise control of single-neuron spiking by juxtacellular nanostimulation

2017

Temporal patterns of action potentials influence a variety of activity-dependent intra- and intercellular processes and play an important role in theories of neural coding. Elucidating the mechanisms underlying these phenomena requires imposing spike trains with precisely defined patterns, but this has been challenging due to the limitations of existing stimulation techniques. Here we present a new nanostimulation method providing control over the action potential output of individual cortical neurons. Spikes are elicited through the juxtacellular application of short-duration fluctuating currents (“kurzpulses”), allowing for the sub-millisecond precise and reproducible induction of arbitr…

Comparison of Different Hypotheses Regarding the Spread of Alzheimer’s Disease Using Markov Random Fields and Multimodal Imaging

2018

Alzheimer’s disease (AD) is characterized by a cascade of pathological processes that can be assessed in vivo using different neuroimaging methods. Recent research suggests a systematic sequence of pathogenic events on a global biomarker level, but little is known about the associations and dependencies of distinct lesion patterns on a regional level. Markov random fields are a probabilistic graphical modeling approach that represent the interaction between individual random variables by an undirected graph. We propose the novel application of this approach to study the interregional associations and dependencies between multimodal imaging markers of AD pathology and to compare different hy…

Associations between cognitive performance and the rehabilitation, medical care and social support provided to French children with Prader-Willi synd…

2020

International audience; Prader-Willi syndrome (PWS) is a rare genetic neurodevelopmental disorder with a characteristic behavioural phenotype. A multidisciplinary approach to care is required to prevent multiple medical complications in individuals affected by PWS. The aim of this study was to describe the rehabilitation, medical care, educational and social support provided to school-aged French PWS patients with varying neuropsychological profiles. Data were obtained from a French multicentre study that included patients aged 4-20 years with diverse genetic syndromes. Nineteen PWS subjects with a mean age of 9.2 years were included. The mean full-scale intellectual quotient (IQ) was 58 (W…