Search results for " Nuclear Medicine and Imaging"

Novel simple templates for reproducible positioning of skin applicators in brachytherapy.

2016

Purpose : Esteya and Valencia surface applicators are designed to treat skin tumors using brachytherapy. In clinical practice, in order to avoid errors that may affect the treatment outcome, there are two issues that need to be carefully addressed. First, the selected applicator for the treatment should provide adequate margin for the target, and second, the applicator has to be precisely positioned before each treatment fraction. In this work, we describe the development and use of a new acrylic templates named Template La Fe-ITIC. They have been designed specifically to help the clinical user in the selection of the correct applicator, and to assist the medical staff in reproducing the po…

Ecografía intestinal y abdomen agudo: más allá de la apendicitis aguda

2021

Resumen El abdomen agudo es un motivo de consulta habitual en los servicios de urgencias. Sus causas son multiples, y entre ellas se encuentran diversas enfermedades del tracto gastrointestinal. Si bien la tomografia computarizada es la tecnica mas aceptada, con frecuencia se lleva a cabo una ecografia abdominal inicialmente, mediante la cual es posible establecer la sospecha de patologia intestinal. Este articulo describe las caracteristicas ecograficas de diversos trastornos intestinales que cursan con abdomen agudo, como la diverticulitis aguda, la obstruccion intestinal, la perforacion gastrointestinal, la isquemia intestinal, la necrosis aguda de la grasa intraabdominal y una miscelane…

Paraganglioma carotídeo maligno. A propósito de un caso

2019

Resumen Los tumores del cuerpo carotideo son neoplasias poco frecuentes, de lento crecimiento, muy destructivos y vascularizados, que tienen un origen neuroectodermico. Los tumores malignos representan el 5-13% de los casos y presentan un comportamiento agresivo local con infiltracion de los ganglios linfaticos adyacentes o metastasis a distancia. Presentamos el caso de un varon de 60 anos al que en el estudio por dolor y parestesias en miembro superior se le realiza una resonancia magnetica donde se visualiza una gran tumoracion en el espacio carotideo izquierdo, la cual se biopsio obteniendo el diagnostico histologico de paraganglioma. Al realizar el estudio de extension se identifico la …

Anatomia e patologia del labirinto membranoso studio con sequenze RM sensibili al flusso

1994

Nonostante i deludenti esordi nella valutazione delle strutture labirintiche costituenti l'orecchio interno, la risonanza magnetica costituisce oggi, grazie anche al miglioramento dell'hardware e del software disponibili, una modalità diagnostica di grande efficacia non solo nell'analisi della patologia espansiva o infiammatoria coinvolgente il VII ed VIII nervo cranico, ma anche nella valutazione delle alterazioni patologiche del segnale endolabirintico in rapporto a focolai emorragici o, come recentemente dimostrato mediante uso di Gd-DTPA, nell'analisi delle alterazioni a carico della capsula oticanella fase spongiotica dell'otosclerosi. Tuttavia, lo scarso contrasto esistente tra liqui…

Análisis estructural cuantitativo del hueso alveolar trabecular de la mandíbula en tomografía computarizada multidetector: diferencias por tipo y est…

2019

Resumen Antecedentes y objetivo Existe una carencia de metricas cuantitativas de la calidad del hueso trabecular alveolar, factor determinante en implantologia. El objetivo de este estudio es desarrollar una metodologia con tomografia computarizada multidetector para objetivar la calidad del hueso trabecular y establecer diferencias entre los distintos tipos y el estado de las piezas dentarias mediante procesado de imagenes y analisis estructural. Materiales y metodos Se analizan 20 pacientes con exploracion de tomografia computarizada multidetector dental para la valoracion del hueso mandibular y posiciones dentales. El analisis de las imagenes incluyo la segmentacion automatica de la mand…

WITHDRAWN: Nouvelles stratégies innovantes en immunothérapie

2018

UVER and UV index at high altitude in Northwestern Argentina

2016

Measurements of ultraviolet erythemal radiation (UVER) made during two years at three sites located at altitudes over 1000 m a.s.l. in Northwestern Argentina (Salta, San Carlos, and El Rosal) have been used to estimate and analyze the UV Index (UVI) and the cumulative doses at these locations. For the UVER irradiance, data of January (maximum values) and June (minimum values) have been analyzed as representative of the year for all locations. The UVI reaches extreme (> 11) values in > 20% of the analyzed days in Salta (1190 m a.s.l.), while these are reached in San Carlos (1611 m a.s.l.) and El Rosal (3355 m a.s.l.) in > 40% of the analyzed days. Finally, the cumulative doses over an averag…

The role of tumor-associated macrophages in gastric cancer development and their potential as a therapeutic target.

2020

Gastric cancer (GC) represents the fifth cause of cancer-related death worldwide. Molecular biology has become a central area of research in GC and there are currently at least three major classifications available to elucidate the mechanisms that drive GC oncogenesis. Further, tumor microenvironment seems to play a crucial role, and tumor-associated macrophages (TAMs) are emerging as key players in GC development. TAMs are cells derived from circulating chemokine- receptor-type 2 (CCR2) inflammatory monocytes in blood and can be divided into two main types, M1 and M2 TAMs. M2 TAMs play an important role in tumor progression, promoting a pro-angiogenic and immunosuppressive signal in the tu…

Toll like receptor mediated immune stimulation can be visualized in vivo by [ 18 F]FDG-PET

2016

Abstract Introduction High uptake of [ 18 F]-2-fluorodeoxyglucose ([ 18 F]FDG) by inflammatory cells is a frequent cause of false positive results in [ 18 F]FDG-positron-emission tomography (PET) for cancer diagnostics. Similar to cancer cells, immune cells undergo significant increases in glucose utilization following activation, e.g., in infectious diseases or after vaccination during cancer therapy. The aim of this study was to quantify certain immune effects in vitro and in vivo by [ 18 F]FDG-PET after stimulation with TLR ligands and specific antibodies. Methods In vivo [ 18 F]FDG-PET/magnetic resonance imaging (MRI) and biodistribution was performed with C57BL/6 mice immunized with Cp…

The Barrett‐associated variants at GDF 7 and TBX 5 also increase esophageal adenocarcinoma risk

2016

Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) represent two stages within the esophagitis-metaplasia-dysplasia-adenocarcinoma sequence. Previously genetic risk factors have been identified that confer risk to BE and EAC development. However, to which extent the genetic variants confer risk to different stages of the BE/EAC sequence remains mainly unknown. In this study we analyzed three most recently identified BE variants at the genes GDF7 (rs3072), TBX5 (rs2701108), and ALDH1A2 (rs3784262) separately in BE and EAC samples in order to determine their risk effects during BE/EAC sequence. Our data show that rs3072 at GDF7 and rs2701108 at TBX5 are also associated with EAC and …