Search results for " Nucleotide"

showing 10 items of 1184 documents

Three chromosomal rearrangements promote genomic divergence between migratory and stationary ecotypes of Atlantic cod

2016

AbstractIdentification of genome-wide patterns of divergence provides insight on how genomes are influenced by selection and can reveal the potential for local adaptation in spatially structured populations. In Atlantic cod – historically a major marine resource – Northeast-Arctic- and Norwegian coastal cod are recognized by fundamental differences in migratory and non-migratory behavior, respectively. However, the genomic architecture underlying such behavioral ecotypes is unclear. Here, we have analyzed more than 8.000 polymorphic SNPs distributed throughout all 23 linkage groups and show that loci putatively under selection are localized within three distinct genomic regions, each of sev…

0106 biological sciences0301 basic medicineLinkage disequilibriumHeterozygoteGenotypePopulation010603 evolutionary biology01 natural sciencesGenomePolymorphism Single NucleotideArticleLinkage Disequilibrium03 medical and health sciencesVDP::Matematikk og naturvitenskap: 400::Basale biofag: 470::Genetikk og genomikk: 474Genetic variationAnimals14. Life underwatereducationLocal adaptationGeneticsEcotypeGene Rearrangementeducation.field_of_studyMultidisciplinaryGenomeEcotypebiologyGenetic VariationBayes TheoremGene rearrangementbiology.organism_classificationVDP::Mathematics and natural scienses: 400::Basic biosciences: 470::Genetics and genomics: 474030104 developmental biologyGadus morhuaEvolutionary biologyAnimal MigrationAtlantic codScientific Reports
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Genomic processes underlying rapid adaptation of a natural Chironomus riparius population to unintendedly applied experimental selection pressures

2020

Evolve and Resquence (E&R) studies are a useful tool to study genomic processes during rapid adaptation, e.g., in the framework of adaptive responses to global climate change. We applied different thermal regimes to a natural Chironomus riparius (Diptera) population in an E&R framework to infer its evolutionary potential for rapid thermal adaptation. We exposed two replicates to three temperatures each (14°C, 20°C and 26°C) for more than two years, the experiment thus lasting 22, 44 or 65 generations, respectively. The two higher temperatures presented a priori moderate, respectively strong selection pressures. Life-cycle fitness tests revealed no appreciable adaptation to thermal regimes b…

0106 biological sciences0301 basic medicineMultifactorial InheritanceClimate ChangePopulationved/biology.organism_classification_rank.speciesSingle-nucleotide polymorphismBiologyPolymorphism Single Nucleotide010603 evolutionary biology01 natural sciencesChironomidae03 medical and health sciencesGene FrequencyGenetic variationGeneticsAnimalsSelection GeneticeducationGeneAllele frequencyEcology Evolution Behavior and SystematicsChironomus ripariusLife Cycle Stageseducation.field_of_studyved/biologySelection coefficientTemperatureGenomicsAdaptation PhysiologicalBiological EvolutionGenetics Population030104 developmental biologyEvolutionary biologyMolecular Ecology
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Sorting Motifs Involved in the Trafficking and Localization of the PIN1 Auxin Efflux Carrier

2016

In contrast with the wealth of recent reports about the function of μ-adaptins and clathrin adaptor protein (AP) complexes, there is very little information about the motifs that determine the sorting of membrane proteins within clathrin-coated vesicles in plants. Here, we investigated putative sorting signals in the large cytosolic loop of the Arabidopsis (Arabidopsis thaliana) PIN-FORMED1 (PIN1) auxin transporter, which are involved in binding μ-adaptins and thus in PIN1 trafficking and localization. We found that Phe-165 and Tyr-280, Tyr-328, and Tyr-394 are involved in the binding of different μ-adaptins in vitro. However, only Phe-165, which binds μA(μ2)- and μD(μ3)-adaptin, was found …

0106 biological sciences0301 basic medicinePhysiologyPhenylalanineGreen Fluorescent ProteinsMutantArabidopsisPlant ScienceProtein Sorting SignalsEndoplasmic ReticulumEndocytosis01 natural sciencesClathrin03 medical and health sciencesCytosolGeneticsGuanine Nucleotide Exchange FactorsSecretory pathwaybiologyArabidopsis ProteinsEndoplasmic reticulumMembrane Transport ProteinsSignal transducing adaptor proteinArticlesPlants Genetically ModifiedClathrinEndocytosisAdaptor Protein Complex mu SubunitsTransport proteinCell biologyProtein Transport030104 developmental biologyProtein Sorting SignalsMutationbiology.protein010606 plant biology & botanyPlant Physiology
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Not that clean: Aquaculture-mediated translocation of cleaner fish has led to hybridization on the northern edge of the species' range

2021

Translocation and introduction of non-native organisms can have major impacts on local populations and ecosystems. Nevertheless, translocations are common practices in agri- and aquaculture. Each year, millions of wild-caught wrasses are transported large distances to be used as cleaner fish for parasite control in marine salmon farms. Recently, it was documented that translocated cleaner fish are able to escape and reproduce with local wild populations. This is especially a challenge in Norway, which is the world's largest salmon producer. Here, a panel of 84 informative SNPs was developed to identify the presence of nonlocal corkwing wrasse (Symphodus melops) escapees and admixed individu…

0106 biological sciences0301 basic medicineRange (biology)EvolutionSpecies distributionContext (language use)VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920::Akvakultur: 922parasitesCleaner fish010603 evolutionary biology01 natural sciences03 medical and health sciencesAquacultureLabridaesingle nucleotide polymorphismGeneticsQH359-425Ecology Evolution Behavior and SystematicsLocal adaptationhuman‐mediated gene flowbiologybusiness.industryEcologyOriginal Articlesgenetic hybridizationbiology.organism_classification030104 developmental biologyaquacultureWrasseOriginal ArticleGeneral Agricultural and Biological SciencesbusinessCorkwing wrasse
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50,000 years of ice and seals: Impacts of the Last Glacial Maximum on Antarctic fur seals

2021

Abstract Ice is one of the most important drivers of population dynamics in polar organisms, influencing the locations, sizes, and connectivity of populations. Antarctic fur seals, Arctocephalus gazella, are particularly interesting in this regard, as they are concomitantly reliant on both ice‐associated prey and ice‐free coastal breeding areas. We reconstructed the history of this species through the Last Glacial Maximum (LGM) using genomic sequence data from seals across their range. Population size trends and divergence events were investigated using continuous‐time size estimation analysis and divergence time estimation models. The combined results indicated that a panmictic population …

0106 biological sciences570Demographic historyRange (biology)Population590010603 evolutionary biology01 natural sciences03 medical and health sciencessingle nucleotide polymorphismsPeninsulaVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 47014. Life underwaterglacial refugiaeducationEcology Evolution Behavior and SystematicsQH540-549.5030304 developmental biologyNature and Landscape ConservationOriginal Research0303 health sciencesPanmixiaeducation.field_of_studygeography.geographical_feature_categorybiologyEcologyPopulation sizeArctocephalus gazellaLast Glacial Maximumbiology.organism_classificationdemographic historyGeographyPhysical geographyArctocephalus gazella
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How challenging RADseq data turned out to favor coalescent-based species tree inference. A case study in Aichryson (Crassulaceae)

2022

Analysing multiple genomic regions while incorporating detection and qualification of discordance among regions has become standard for understanding phylogenetic relationships. In plants, which usually have comparatively large genomes, this is feasible by the combination of reduced-representation library (RRL) methods and high-throughput sequencing enabling the cost effective acquisition of genomic data for thousands of loci from hundreds of samples. One popular RRL method is RADseq. A major disadvantage of established RADseq approaches is the rather short fragment and sequencing range, leading to loci of little individual phylogenetic information. This issue hampers the application of coa…

0106 biological sciences570clustering threshold selectionInferenceLocus (genetics)Computational biologyBiologyCrassulaceaedata bias010603 evolutionary biology01 natural sciencesGenomeCoalescent theoryspecies tree inference03 medical and health scienceslocus filteringGeneticscoalescent-based summary methodCluster analysisMolecular BiologyEcology Evolution Behavior and SystematicsSelection (genetic algorithm)Phylogeny030304 developmental biology0303 health sciencesGenomePhylogenetic treeHigh-Throughput Nucleotide SequencingGenomicsRADseq500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; BiologieTree (data structure)
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Phylogenomics Identifies an Ancestral Burst of Gene Duplications Predating the Diversification of Aphidomorpha

2019

Aphids (Aphidoidea) are a diverse group of hemipteran insects that feed on plant phloem sap. A common finding in studies of aphid genomes is the presence of a large number of duplicated genes. However, when these duplications occurred remains unclear, partly due to the high relatedness of sequenced species. To better understand the origin of aphid duplications we sequenced and assembled the genome of Cinara cedri, an early branching lineage (Lachninae) of the Aphididae family. We performed a phylogenomic comparison of this genome with 20 other sequenced genomes, including the available genomes of five other aphids, along with the transcriptomes of two species belonging to Adelgidae (a close…

0106 biological sciences:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]Gene duplicationAphidomorphaLineage (evolution)010603 evolutionary biology01 natural sciencesGenomeSyntenyDNA sequencingFilogèniaEvolution Molecular03 medical and health sciencessequencia genómicaSpecies SpecificityPhylogenomicsGene duplicationBioinformaticaGeneticsAdelgidaeAnimalsMolecular BiologyEcology Evolution Behavior and SystematicsDiscoveriesPhylogeny030304 developmental biologySegmental duplication0303 health sciencesAphidbiologyWhole Genome SequencingGene Expression Profilinggene duplicationfood and beveragesHigh-Throughput Nucleotide SequencingAfidomorfabiochemical phenomena metabolism and nutritionbiology.organism_classificationaphidsGenòmicaGene Expression RegulationEvolutionary biologyAphidsInsect ProteinsGenèticaMolecular Biology and Evolution
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The Spodoptera exigua ABCC2 Acts as a Cry1A Receptor Independently of its Nucleotide Binding Domain II

2019

ABC proteins are primary-active transporters that require the binding and hydrolysis of ATP to transport substrates across the membrane. Since the first report of an ABCC2 transporter as receptor of Cry1A toxins, the number of ABC transporters known to be involved in the mode of action of Cry toxins has increased. In Spodoptera exigua, a mutation in the SeABCC2 gene is described as genetically linked to resistance to the Bt-product XentariTM. This mutation affects an intracellular domain involved in ATP binding, but not the extracellular loops. We analyzed whether this mutation affects the role of the SeABCC2 as a functional receptor to Cry1A toxins. The results show that Sf21 cells express…

0106 biological sciencesCell SurvivalHealth Toxicology and Mutagenesislcsh:MedicineReceptors Cell SurfaceATP-binding cassette transporterSpodopteraSpodopteraToxicologymedicine.disease_causeBt resistance01 natural sciencesArticleCell LineHemolysin Proteins03 medical and health sciencesBacterial Proteinsmode of actionGTP-Binding ProteinsATP hydrolysismedicineAnimalsReceptor030304 developmental biology0303 health sciencesMutationBacillus thuringiensis ToxinsbiologyChemistryfungilcsh:Rheterologous expressionTransporterbiology.organism_classificationMultidrug Resistance-Associated Protein 2Cell biologyEndotoxins010602 entomologyCyclic nucleotide-binding domainSf21 cellstruncated transporterInsect ProteinsHeterologous expressionMultidrug Resistance-Associated ProteinsToxins
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The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild

2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.

0106 biological sciencesConservation geneticsMalegenotype phenotype correlationGorillaComputingMilieux_LEGALASPECTSOFCOMPUTINGarginineGenoma humà01 natural sciencesOculocutaneous albinism type 4single nucleotide polymorphismAlbinismegenetic variabilityGorillaInbreedinggenetic conservationGenetics0303 health sciencesGenomebiologyarticlecopy number variationHigh-Throughput Nucleotide SequencingSLC45A2 geneGenomicszygosityOculocutaneous albinismFloquet de neu (Goril·la)AlbinismFemaleBiotechnologyamino acid substitutionResearch ArticleSLC45A2Gorilla gorilla gorillaHeterozygoteAlbinismMolecular Sequence Datacomparative genomic hybridizationgene sequenceConservation010603 evolutionary biology03 medical and health sciencesWestern lowland gorillabiology.animalmedicineGeneticsheterozygosityAnimalsAmino Acid Sequencegene030304 developmental biologygene identificationWhole genome sequencingnonhumanGorilla gorillaMembrane Transport ProteinsSequence Analysis DNA15. Life on landbiology.organism_classificationmedicine.diseaseGenòmicaData_GENERALMutationbiology.proteinGenèticaoculocutaneous albinismglycineMicrosatellite RepeatsBMC Genomics
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Nested core collections maximizing genetic diversity in Arabidopsis thaliana.

2004

Summary The successful exploitation of natural genetic diversity requires a basic knowledge of the extent of the variation present in a species. To study natural variation in Arabidopsis thaliana, we defined nested core collections maximizing the diversity present among a worldwide set of 265 accessions. The core collections were generated based on DNA sequence data from a limited number of fragments evenly distributed in the genome and were shown to successfully capture the molecular diversity in other loci as well as the morphological diversity. The core collections are available to the scientific community and thus provide an important resource for the study of genetic variation and its …

0106 biological sciencesDNA PlantArabidopsisSingle-nucleotide polymorphismPlant Science01 natural sciencesGenomePolymorphism Single NucleotideDNA sequencing[SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics03 medical and health sciencesArabidopsis[SDV.GEN.GPL] Life Sciences [q-bio]/Genetics/Plants geneticsGenetic variationGeneticsArabidopsis thalianaComputingMilieux_MISCELLANEOUS030304 developmental biologyGenetic associationGenetics0303 health sciencesGenetic diversitybiologyGenetic VariationCell Biology15. Life on landbiology.organism_classificationPhenotypeEvolutionary biologyhuman activitiesGenome Plant010606 plant biology & botanyThe Plant journal : for cell and molecular biology
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