Search results for " Open source"
showing 10 items of 19 documents
Dry selection and wet evaluation for the rational discovery of new anthelmintics
2017
Helminths infections remain a major problem in medical and public health. In this report, atom-based 2D bilinear indices, a TOMOCOMD-CARDD (QuBiLs-MAS module) molecular descriptor family and linear discriminant analysis (LDA) were used to find models that differentiate among anthelmintic and non-anthelmintic compounds. Two classification models obtained by using non-stochastic and stochastic 2D bilinear indices, classified correctly 86.64% and 84.66%, respectively, in the training set. Equation 1(2) correctly classified 141(135) out of 165 [85.45%(81.82%)] compounds in external validation set. Another LDA models were performed in order to get the most likely mechanism of action of anthelmin…
QuBiLS-MAS, open source multi-platform software for atom- and bond-based topological (2D) and chiral (2.5D) algebraic molecular descriptors computati…
2017
Background In previous reports, Marrero-Ponce et al. proposed algebraic formalisms for characterizing topological (2D) and chiral (2.5D) molecular features through atom- and bond-based ToMoCoMD-CARDD (acronym for Topological Molecular Computational Design-Computer Aided Rational Drug Design) molecular descriptors. These MDs codify molecular information based on the bilinear, quadratic and linear algebraic forms and the graph-theoretical electronic-density and edge-adjacency matrices in order to consider atom- and bond-based relations, respectively. These MDs have been successfully applied in the screening of chemical compounds of different therapeutic applications ranging from antimalarials…
A More Simple G-Code Programming within an Open Source CNC System
2006
In this paper we introduce the utilization of a new CNC programming language, named O-Word, a way to implement several branching routines into the EMC interpreter. It opens new interesting possibilities to programmers who can build subroutines, loops, and conditionals while taking advantage of the interpreter's use of variables and computation. Therefore, it allows us to make pieces describing theirs features instead of tool's movements. We will demonstrate a new complex routine in order to show both the language syntax and its potential for advanced applications.
INTERNET BASED DEVELOPMENT OF AN OPEN SOURCE LOW-COST CNC
2006
In this paper we show how to realize a low-cost numerical system, based on an “open source” software called EMC (Enhanced Machine Control). First, we assembled a low cost CNC workstation with a remote control by means of an online computer with a webcam, as an example of the software's potentiality. Moreover, we translated a graphical user interface (AXIS), in co-operation with the international development community, in order to improve its userfriendliness.
A Web based remote control of CNC machines
2009
Due to the large variety of products in small batch sizes, a modern machining shop floor requires an advanced real-time control system able to both monitor all the features and adapt the manufacturing system to the rapid changes of production capability and functionality. This is especially true when the shop floors are combined with the e-Manufacturing concept. e-Manufacturing is a transformation system which enables the manufacturing operations to achieve a predictive near-zero-downtime performance as well as to synchronize with the management systems through the use of infotronics technologies (i.e., wireless connections, web applications, networking systems, etc.). In recent years, the …
Low‐cost, High‐Capability, Embedded Systems for CNC Education and Research
2015
Teaching of CNC and CAD/CAM technologies has recently taken a great importance, due to their development, to the great number of solutions available on the market, and to the frequent updates. Nevertheless, one of the most urgent need is to improve the quality of education coping with a rapidly growing number of students. Nowadays, in comparison to the past, many Open-Source technical solutions, both hardware and software, are available to realise easily and cheaply some scaled-down prototypes of numerical control machine tools: these are able to work perfectly and can be employed as a learning method. This paper shows some past experiences regarding the development of some degree thesis wo…
UN SIT PER IL PPE DEL CENTRO STORICO DI PALERMO: IL CASO STUDIO DEL MANDAMENTO CASTELLAMMARE
2015
In this work a Geographic Information System was realised at the service of municipal administration of Palermo, to integrate, manage and store city plan information regarding the urban district Castellammare whereof detailed executive plan of inner city, correlating basic cartography, current urban instrument, cadastral cartography, current restriction schemes, monumental and historical monuments, street numbers and street network. Quantum GIS vers. 1.8 of Free and Open-Source Software (FOSS) community was exclusively utilized to the fulfilment of GIS. To the experimentation and the fulfilment of WebGIS a free server was used in cloud on the Amazon, where a virtual machine, based on MapSer…
An Efficient NURBS Path Generator for a Open Source CNC
2014
In this paper a NURBS path generator (on the plane XY) is proposed to be developed for those CNC machine tools and robot which are Open Source or Opening Architecture. The goal is to use simple and efficient techniques to manufacture geometries which are very complex, whose main feature is the presence of free-form surfaces and contours. To reach this goal, the NURBS path generator has been optimized in order to enable the user to select among three different options to generate the tool path, using a specific parameter. The three options are respectively called “NURBS interpolation with constant increments of u parameter” (NICU), “NURBS interpolation with constant displacement increments b…
Aula Virtual. Evolució del maquinari i millora de resultats
2009
Las Tecnologías de la Información y la Comunicación (TIC) han contribuido al desarrollo de plataformas e.learning de apoyo a los procesos de enseñanza-aprendizaje. Actualmente, la mayoría de universidades cuentan con algún tipo de sistema de gestión del aprendizaje (en inglés, LMS). El óptimo uso de estas plataformas requiere que integren las aplicaciones preexistentes de forma transparente. Esto se consigue con el uso de una arquitectura robusta. En este artículo expondremos la implementación y arquitectura del LMS integrado de la Universitat de València y la evolución de su hardware para adecuarse de manera óptima a las necesidades de la universidad.
Il paradigma proprietario e l'appropriazione dell'immateriale
2014
Uno studio sui paradigmi dell'appropriazione materiale e immateriale, con particolare attenzione per il diritto privato europeo e dalle prospettive dei limiti dei diritti e dell'evoluzione tecnologica. A study on the paradigms of the material and immaterial appropriation, with particular attention to the european private law and from the perspective of limitations to the rights and technological innovation.