Search results for " Order"

showing 10 items of 827 documents

Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1)

2001

Human chromosome 11p15.3 is associated with chromosome aberrations in the Beckwith Wiedemann Syndrome and implicated in the pathogenesis of different tumor types including lung cancer and leukemias. To date, only single tumor-relevant genes with linkage to this region (e.g. LMO1) have been found suggesting that this region may harbor additional potential disease associated genes. Although this genomic area has been studied for years, the exact order of genes/chromosome markers between D11S572 and the WEE1 gene locus remained unclear. Using the FISH technique and PAC clones of the flanking markers we determined the order of the genomic markers. Based on these clones we established a PAC cont…

Genetic Markerscongenital hereditary and neonatal diseases and abnormalitiesBeckwith–Wiedemann syndromeCell Cycle ProteinsBiologyChromosomesEvolution MolecularContig MappingMiceChromosome regionsGene OrderMetalloproteinsGeneticsmedicineAnimalsHumansCloning MolecularMolecular BiologyGeneConserved SequenceIn Situ Hybridization FluorescenceGenetics (clinical)Repetitive Sequences Nucleic AcidSyntenyOncogene ProteinsGeneticsChromosome 7 (human)Base CompositionChromosomes Human Pair 11Nuclear ProteinsChromosomeSequence Analysis DNALIM Domain ProteinsProtein-Tyrosine Kinasesmedicine.diseaseAT Rich SequenceGC Rich SequenceDNA-Binding ProteinsChromosome 3CpG IslandsChromosome 21Transcription FactorsCytogenetic and Genome Research
researchProduct

Liver-specific overexpression of matrix metalloproteinase 9 (MMP-9) in transgenic mice accelerates development of hepatocellular carcinoma.

2010

Matrix metalloproteinase-9 (MMP-9) plays a central role in tumor invasion and development of metastases. Expression of MMP-9 had been shown in human hepatocellular carcinomas (HCCs). However, it remained unclear whether MMP-9 could influence development of HCC. In order to address this issue, we generated transgenic mice overexpressing MMP-9 in the liver. In order to avoid embryonic lethality a Cre-lox system was utilized for conditional overexpression of MMP-9 under control of an albumin enhancer and promoter. Induction of MMP-9 overexpression in transgenic mice was achieved by i.v. injection of an adenovirus coding for the Cre recombinase. Initiation of liver carcinogenesis was achieved b…

Genetically modified mouseCancer ResearchLiver tumorTransgeneGenetic VectorsCre recombinaseGene ExpressionMice TransgenicBiologymedicine.disease_causeMiceLiver Neoplasms ExperimentalIn vivoGene OrdermedicineAnimalsHomeostasisHumansHomologous RecombinationMolecular BiologyIntegrasesHCCSmedicine.diseaseMolecular biologyCell Transformation NeoplasticPhenotypeLiverMatrix Metalloproteinase 9Organ SpecificityHepatocellular carcinomaCarcinogenesisMolecular carcinogenesis
researchProduct

Geomorphologic Risk Modelling of the Sibiu Depression Using Geospatial Surface Analyses

2011

Extreme events in general, and the geomorphologic ones in particular, are highly topical problems. There were addresses by many researchers in the field of geology and physical geography (more specific by the climatologists and geomorphologists), but also by biologists, chemists, ecologists, etc. These are studied through the analysis of some types of processes and production mechanisms, and secondly by the effects they create on other environmental subsystems.

Geospatial analysisGeographybusiness.industryEnvironmental resource managementExtreme eventsStream orderRill erosioncomputer.software_genrebusinesscomputerCartographyField (geography)
researchProduct

How we compensate for memory loss in old age: adapting and validating the Memory Compensation Questionnaire (MCQ) for Spanish populations.

2012

Compensating entails using external strategies and mechanisms that help overcome or alleviate the decreasing memory function that comes with age. This study aims to adapt and validate the MCQ in the elderly Spanish population. A total of 403 elderly people aged between 65 and 92 in the city of Valencia (Spain) completed the questionnaire for the validation process. The factorial validity of the scale was tested using confirmatory factor analysis. The result showed a first order five-factor model with 23 items that met the criteria for model fit according to multiple fit indices. As a general conclusion, the adaptation into Spanish provided a reliable and valid measure of compensation in the…

GerontologyMaleAgingHealth (social science)Structural equation modelingSurveys and QuestionnairesAdaptation PsychologicalElderly peopleHumansAgedAged 80 and overMemory DisordersPsychological TestsCompensation (psychology)Reproducibility of ResultsFirst orderConfirmatory factor analysisSpanish populationClinical PracticeSpainScale (social sciences)FemaleGeriatrics and GerontologyPsychologyFactor Analysis StatisticalGerontologyArchives of gerontology and geriatrics
researchProduct

Can New Information and Communication Technologies Influence the World Order?

2012

The paper aims to shocase that new ICTs do influence the world order. It gives examples and concrete cases and showcases how ICTs are used to impact the world order.

GlobalizationEconomic growthGeographyInformation and Communications TechnologyComputerApplications_MISCELLANEOUSRegional scienceICTSWorld orderSSRN Electronic Journal
researchProduct

From Cottesloe (1961) to Trondheim (2016): The journey of the Dutch Reformed Church back into the ecumenical family of the World Council of Churches

2018

This article presents an analysis of the journey of the Dutch Reformed Church (South Africa) back into the ecumenical fellowship of the World Council of Churches (WCC). The first part contains a brief historical review of the relationships between the WCC and the Dutch Reformed Church family, underlining the fact that the Dutch Reformed Church family in South Africa is a founding member of WCC and that it was never excluded from WCC fellowship; rather, this church itself resigned membership in the WCC after the Cottesloe Consultation (1961) at the pressure of the South African government of that time. The last part presents in detail the process of the readmission of the Dutch Reformed Chur…

Governmentlcsh:BS1-2970Cottesloe; Dutch Reformed Church; membership in WCC; WCC Central Committee in Trondheim; Faith and Order Commission meeting in JohannesburgReligious studiesFaith and Order Commission meeting in JohannesburgWCC Central Committee in TrondheimDutch Reformed Churchlcsh:The Biblelcsh:BV1-5099membership in WCCPolitical scienceLawlcsh:Practical TheologyCottesloeHTS Teologiese Studies / Theological Studies
researchProduct

Gravity Anomalies Over The Gongola Arm, Upper Benue Trough, Nigeria

2005

A regional gravity survey of the Gongola Arm of the Benue trough was carried out with the aim of determining structures of interest. The results of the gravity interpretation showed that the area of study is characterized by negative Bouguer anomalies that trend in the NE-SW direction and range in value from -75 to -15 mGal with an average of -42 mGal. A first order polynomial was used to approximate the regional anomalies in the area. The residual gravity anomaly map shows anomalies that range in value from -32 to +20 mGal. 2.5-D modeling of the residual gravity anomalies suggests that the area has a horst and graben structure, with the grabens being as large as 60 km in width and filled w…

GrabenGravity (chemistry)Horst and grabenHalf-grabenTrough (geology)First orderSeismologyGravity anomalyGeologyGlobal Journal of Geological Sciences
researchProduct

Parallel Algorithms for Listing Well-Formed Parentheses Strings

1998

We present two cost-optimal parallel algorithms generating the set of all well-formed parentheses strings of length 2n with constant delay for each generated string. In our first algorithm we generate in lexicographic order well-formed parentheses strings represented by bitstrings, and in the second one we use the representation by weight sequences. In both cases the computational model is based on an architecture CREW PRAM, where each processor performs the same algorithm simultaneously on a different set of data. Different processors can access the shared memory at the same time to read different data in the same or different memory locations, but no two processors are allowed to write i…

Gray codeSet (abstract data type)Shared memoryHardware and ArchitectureComputer scienceString (computer science)Parallel algorithmParallel random-access machineLexicographical orderTime complexityAlgorithmSoftwareTheoretical Computer ScienceParallel Processing Letters
researchProduct

Datorzinātne un informācijas tehnoloģijas

2011

Grover’s algorithmHigher order transformationsOntologyBusiness process controlSoftware development:TECHNOLOGY::Information technology::Computer science [Research Subject Categories]Quantum computingModel-driven developmentTool definition metamodelData browsingTransformation-driven architectureGraphical tool buildingCubic spline interpolationGUILanguages for model-driven developmentRelational databases
researchProduct

Campagnes, migrations internationales et nouvel ordre social ethnicisé. La zone viticole Utiel-Requena (Espagne)

2021

Utiel-Requena est une zone viticole traditionnelle de la province de Valence (Espagne), qui a connu une importante restructuration productive, l’arrivée de travailleurs immigrants et leur enracinement familial. Cet article aborde cette installation et les changements qu’elle a générés dans ces municipalités. Notre analyse des différentes sphères de la vie locale, telles que le travail, les espaces et services publics, la coexistence et les représentations symboliques, montre la constitution d’un ordre social ethnicisé qui consolide la position subalterne des immigrants et de leurs descendants. Utiel-Requena is a traditional wine-growing area in the province of Valencia (Spain), which has un…

H1-99ordre social ethniciséEspagneGeography Planning and Developmenttravailleurs immigrésenracinement familialDesenvolupament ruralrestructuration du secteur vitivinicolefamily rootingwine sector restructuringethnicized social orderGSocial sciences (General)ValenceSpainGeography. Anthropology. RecreationValenciaimmigrant workersDemographyEspace populations sociétés
researchProduct